DE69427126D1 - Hydrophobe polymer mikropartikel - Google Patents

Hydrophobe polymer mikropartikel

Info

Publication number
DE69427126D1
DE69427126D1 DE69427126T DE69427126T DE69427126D1 DE 69427126 D1 DE69427126 D1 DE 69427126D1 DE 69427126 T DE69427126 T DE 69427126T DE 69427126 T DE69427126 T DE 69427126T DE 69427126 D1 DE69427126 D1 DE 69427126D1
Authority
DE
Germany
Prior art keywords
microparticle
substance
polymer
ionic
hydrophobic polymer
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69427126T
Other languages
English (en)
Other versions
DE69427126T2 (de
Inventor
K Andrianov
S Langer
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Celldex Therapeutics Inc
Original Assignee
Virus Research Institute Inc
Massachusetts Institute of Technology
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Virus Research Institute Inc, Massachusetts Institute of Technology filed Critical Virus Research Institute Inc
Publication of DE69427126D1 publication Critical patent/DE69427126D1/de
Application granted granted Critical
Publication of DE69427126T2 publication Critical patent/DE69427126T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1635—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Processes Of Treating Macromolecular Substances (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
DE69427126T 1993-09-21 1994-09-21 Hydrophobe polymer mikropartikel Expired - Fee Related DE69427126T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/124,816 US5500161A (en) 1993-09-21 1993-09-21 Method for making hydrophobic polymeric microparticles
PCT/US1994/010692 WO1995008320A1 (en) 1993-09-21 1994-09-21 Hydrophobic polymeric microparticles

Publications (2)

Publication Number Publication Date
DE69427126D1 true DE69427126D1 (de) 2001-05-23
DE69427126T2 DE69427126T2 (de) 2001-08-23

Family

ID=22416932

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69427126T Expired - Fee Related DE69427126T2 (de) 1993-09-21 1994-09-21 Hydrophobe polymer mikropartikel

Country Status (11)

Country Link
US (1) US5500161A (de)
EP (1) EP0720471B1 (de)
AT (1) ATE200616T1 (de)
AU (1) AU7800194A (de)
CA (1) CA2172040A1 (de)
DE (1) DE69427126T2 (de)
DK (1) DK0720471T3 (de)
ES (1) ES2159305T3 (de)
GR (1) GR3036224T3 (de)
PT (1) PT720471E (de)
WO (1) WO1995008320A1 (de)

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Also Published As

Publication number Publication date
PT720471E (pt) 2001-08-30
GR3036224T3 (en) 2001-10-31
ES2159305T3 (es) 2001-10-01
WO1995008320A1 (en) 1995-03-30
AU7800194A (en) 1995-04-10
DK0720471T3 (da) 2001-05-07
EP0720471A1 (de) 1996-07-10
CA2172040A1 (en) 1995-03-30
DE69427126T2 (de) 2001-08-23
US5500161A (en) 1996-03-19
EP0720471B1 (de) 2001-04-18
ATE200616T1 (de) 2001-05-15

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