DE69419917D1 - Indazolderivate - Google Patents
IndazolderivateInfo
- Publication number
- DE69419917D1 DE69419917D1 DE69419917T DE69419917T DE69419917D1 DE 69419917 D1 DE69419917 D1 DE 69419917D1 DE 69419917 T DE69419917 T DE 69419917T DE 69419917 T DE69419917 T DE 69419917T DE 69419917 D1 DE69419917 D1 DE 69419917D1
- Authority
- DE
- Germany
- Prior art keywords
- pct
- image
- moiety
- date sep
- sec
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- BAXOFTOLAUCFNW-UHFFFAOYSA-N 1H-indazole Chemical class C1=CC=C2C=NNC2=C1 BAXOFTOLAUCFNW-UHFFFAOYSA-N 0.000 title abstract 2
- VYFYYTLLBUKUHU-UHFFFAOYSA-N dopamine Chemical compound NCCC1=CC=C(O)C(O)=C1 VYFYYTLLBUKUHU-UHFFFAOYSA-N 0.000 abstract 2
- 125000004169 (C1-C6) alkyl group Chemical group 0.000 abstract 1
- 102000015554 Dopamine receptor Human genes 0.000 abstract 1
- 108050004812 Dopamine receptor Proteins 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 229960003638 dopamine Drugs 0.000 abstract 1
- 125000000623 heterocyclic group Chemical group 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 125000003453 indazolyl group Chemical group N1N=C(C2=C1C=CC=C2)* 0.000 abstract 1
- 239000003446 ligand Substances 0.000 abstract 1
- 125000001570 methylene group Chemical group [H]C([H])([*:1])[*:2] 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
- 201000000980 schizophrenia Diseases 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB939305641A GB9305641D0 (en) | 1993-03-18 | 1993-03-18 | Therapeutic agents |
| PCT/GB1994/000503 WO1994021626A1 (en) | 1993-03-18 | 1994-03-14 | Indazole derivatives |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE69419917D1 true DE69419917D1 (de) | 1999-09-09 |
| DE69419917T2 DE69419917T2 (de) | 2000-02-24 |
Family
ID=10732323
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE69419917T Expired - Fee Related DE69419917T2 (de) | 1993-03-18 | 1994-03-14 | Indazolderivate |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US5665732A (de) |
| EP (1) | EP0701555B1 (de) |
| JP (1) | JPH08507780A (de) |
| AT (1) | ATE182891T1 (de) |
| AU (1) | AU679214B2 (de) |
| CA (1) | CA2156839A1 (de) |
| DE (1) | DE69419917T2 (de) |
| ES (1) | ES2133544T3 (de) |
| GB (1) | GB9305641D0 (de) |
| WO (1) | WO1994021626A1 (de) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9305623D0 (en) * | 1993-03-18 | 1993-05-05 | Merck Sharp & Dohme | Therapeutic agents |
| TW421649B (en) * | 1995-01-31 | 2001-02-11 | Janssen Pharmaceutica Nv | 4-(1H-indol-1yl)-1-piperidinyl derivatives |
| GB9523462D0 (en) * | 1995-11-16 | 1996-01-17 | Merck Sharp & Dohme | Therapeutic agents |
| US6187774B1 (en) * | 1996-03-04 | 2001-02-13 | Yoshitomi Pharmaceutical Industries, Ltd. | Fused heterocyclic compounds and pharmaceutical applications thereof |
| ZA9711376B (en) | 1996-12-20 | 1998-07-21 | Lundbeck & Co As H | Indole or dihydroindole derivatives |
| AU6246198A (en) * | 1997-02-18 | 1998-09-08 | American Home Products Corporation | 4-aminoethoxyindazole derivatives |
| US5872144A (en) * | 1997-02-18 | 1999-02-16 | American Home Products Corporation | 4-aminoethoxyindazole derivatives |
| BR9911843A (pt) | 1998-06-19 | 2001-03-20 | Lundbeck & Co As H | 4 5 6 7-indol e derivados de indolina, preparação e utilização dos mesmos |
| HUP0101475A3 (en) * | 1998-06-19 | 2003-01-28 | Lundbeck & Co As H | 4,5,6 and 7-indole and indoline derivatives, their preparation and use |
| KR100704710B1 (ko) * | 1999-10-29 | 2007-04-09 | 주식회사 중외제약 | 간 섬유화 억제작용을 나타내는 벤조[3,4-ｄ]1,3-디옥솔란 유도체 |
| US7094790B2 (en) | 2003-05-07 | 2006-08-22 | Abbott Laboratories | Fused bicyclic-substituted amines as histamine-3 receptor ligands |
| DE102004005172A1 (de) * | 2004-02-02 | 2005-08-18 | Aventis Pharma Deutschland Gmbh | Indazolderivate als Inhibitoren der Hormon Sensitiven Lipase |
| CA2743864A1 (en) * | 2008-11-25 | 2010-06-10 | Merck Sharp & Dohme Corp. | Soluble guanylate cyclase activators |
| WO2017178377A1 (en) * | 2016-04-13 | 2017-10-19 | Ucb Biopharma Sprl | Tetrahydroisoquinoline derivatives |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3488353A (en) * | 1967-05-29 | 1970-01-06 | Sterling Drug Inc | New 1-((2-azaindolyl)-lower-alkyl) 4-substituted-piperazines |
| US3678059A (en) * | 1969-10-07 | 1972-07-18 | Ciba Geigy Corp | 3-aminoalkylidene-indazoles |
| US5116846A (en) * | 1990-03-28 | 1992-05-26 | Du Pont Merck Pharmaceutical Company | N-aralkyl piperidine derivatives as psychotropic drugs |
| NZ243065A (en) * | 1991-06-13 | 1995-07-26 | Lundbeck & Co As H | Piperidine derivatives and pharmaceutical compositions |
| FR2692901B1 (fr) * | 1992-06-26 | 1994-08-19 | Cray Valley Sa | Résines et compositions pour la fabrication de matériaux de haut module résistants à la chaleur et articles moulés obtenus à partir de ces matériaux. |
| HUT71799A (en) * | 1993-03-01 | 1996-02-28 | Merck Sharp & Dohme | Pyrrolo-pyridine derivatives, pharmaceutical compositions containing the same, process for producing them |
-
1993
- 1993-03-18 GB GB939305641A patent/GB9305641D0/en active Pending
-
1994
- 1994-03-14 CA CA002156839A patent/CA2156839A1/en not_active Abandoned
- 1994-03-14 US US08/530,226 patent/US5665732A/en not_active Expired - Fee Related
- 1994-03-14 JP JP6520765A patent/JPH08507780A/ja active Pending
- 1994-03-14 AU AU62139/94A patent/AU679214B2/en not_active Ceased
- 1994-03-14 DE DE69419917T patent/DE69419917T2/de not_active Expired - Fee Related
- 1994-03-14 WO PCT/GB1994/000503 patent/WO1994021626A1/en active IP Right Grant
- 1994-03-14 ES ES94909209T patent/ES2133544T3/es not_active Expired - Lifetime
- 1994-03-14 EP EP94909209A patent/EP0701555B1/de not_active Expired - Lifetime
- 1994-03-14 AT AT94909209T patent/ATE182891T1/de active
Also Published As
| Publication number | Publication date |
|---|---|
| ES2133544T3 (es) | 1999-09-16 |
| WO1994021626A1 (en) | 1994-09-29 |
| CA2156839A1 (en) | 1994-09-29 |
| ATE182891T1 (de) | 1999-08-15 |
| EP0701555A1 (de) | 1996-03-20 |
| JPH08507780A (ja) | 1996-08-20 |
| AU6213994A (en) | 1994-10-11 |
| DE69419917T2 (de) | 2000-02-24 |
| US5665732A (en) | 1997-09-09 |
| GB9305641D0 (en) | 1993-05-05 |
| AU679214B2 (en) | 1997-06-26 |
| EP0701555B1 (de) | 1999-08-04 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8339 | Ceased/non-payment of the annual fee |