ATE182891T1 - Indazolderivate - Google Patents
IndazolderivateInfo
- Publication number
- ATE182891T1 ATE182891T1 AT94909209T AT94909209T ATE182891T1 AT E182891 T1 ATE182891 T1 AT E182891T1 AT 94909209 T AT94909209 T AT 94909209T AT 94909209 T AT94909209 T AT 94909209T AT E182891 T1 ATE182891 T1 AT E182891T1
- Authority
- AT
- Austria
- Prior art keywords
- pct
- image
- moiety
- date sep
- sec
- Prior art date
Links
- BAXOFTOLAUCFNW-UHFFFAOYSA-N 1H-indazole Chemical class C1=CC=C2C=NNC2=C1 BAXOFTOLAUCFNW-UHFFFAOYSA-N 0.000 title abstract 2
- VYFYYTLLBUKUHU-UHFFFAOYSA-N dopamine Chemical compound NCCC1=CC=C(O)C(O)=C1 VYFYYTLLBUKUHU-UHFFFAOYSA-N 0.000 abstract 2
- 125000004169 (C1-C6) alkyl group Chemical group 0.000 abstract 1
- 102000015554 Dopamine receptor Human genes 0.000 abstract 1
- 108050004812 Dopamine receptor Proteins 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 229960003638 dopamine Drugs 0.000 abstract 1
- 125000000623 heterocyclic group Chemical group 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 125000003453 indazolyl group Chemical group N1N=C(C2=C1C=CC=C2)* 0.000 abstract 1
- 239000003446 ligand Substances 0.000 abstract 1
- 125000001570 methylene group Chemical group [H]C([H])([*:1])[*:2] 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
- 201000000980 schizophrenia Diseases 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB939305641A GB9305641D0 (en) | 1993-03-18 | 1993-03-18 | Therapeutic agents |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE182891T1 true ATE182891T1 (de) | 1999-08-15 |
Family
ID=10732323
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT94909209T ATE182891T1 (de) | 1993-03-18 | 1994-03-14 | Indazolderivate |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US5665732A (de) |
| EP (1) | EP0701555B1 (de) |
| JP (1) | JPH08507780A (de) |
| AT (1) | ATE182891T1 (de) |
| AU (1) | AU679214B2 (de) |
| CA (1) | CA2156839A1 (de) |
| DE (1) | DE69419917T2 (de) |
| ES (1) | ES2133544T3 (de) |
| GB (1) | GB9305641D0 (de) |
| WO (1) | WO1994021626A1 (de) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9305623D0 (en) * | 1993-03-18 | 1993-05-05 | Merck Sharp & Dohme | Therapeutic agents |
| TW421649B (en) * | 1995-01-31 | 2001-02-11 | Janssen Pharmaceutica Nv | 4-(1H-indol-1yl)-1-piperidinyl derivatives |
| GB9523462D0 (en) * | 1995-11-16 | 1996-01-17 | Merck Sharp & Dohme | Therapeutic agents |
| US6187774B1 (en) * | 1996-03-04 | 2001-02-13 | Yoshitomi Pharmaceutical Industries, Ltd. | Fused heterocyclic compounds and pharmaceutical applications thereof |
| ZA9711376B (en) | 1996-12-20 | 1998-07-21 | Lundbeck & Co As H | Indole or dihydroindole derivatives |
| US5872144A (en) * | 1997-02-18 | 1999-02-16 | American Home Products Corporation | 4-aminoethoxyindazole derivatives |
| WO1998035942A1 (en) * | 1997-02-18 | 1998-08-20 | American Home Products Corporation | 4-aminoethoxyindazole derivatives |
| AU765317C (en) * | 1998-06-19 | 2004-05-20 | H. Lundbeck A/S | 4,5,6 and 7-indole and indoline derivatives, their preparation and use |
| BR9911843A (pt) | 1998-06-19 | 2001-03-20 | Lundbeck & Co As H | 4 5 6 7-indol e derivados de indolina, preparação e utilização dos mesmos |
| KR100704710B1 (ko) * | 1999-10-29 | 2007-04-09 | 주식회사 중외제약 | 간 섬유화 억제작용을 나타내는 벤조[3,4-ｄ]1,3-디옥솔란 유도체 |
| US7094790B2 (en) | 2003-05-07 | 2006-08-22 | Abbott Laboratories | Fused bicyclic-substituted amines as histamine-3 receptor ligands |
| DE102004005172A1 (de) * | 2004-02-02 | 2005-08-18 | Aventis Pharma Deutschland Gmbh | Indazolderivate als Inhibitoren der Hormon Sensitiven Lipase |
| AU2009322836B2 (en) * | 2008-11-25 | 2013-04-04 | Merck Sharp & Dohme Corp. | Soluble guanylate cyclase activators |
| WO2017178377A1 (en) * | 2016-04-13 | 2017-10-19 | Ucb Biopharma Sprl | Tetrahydroisoquinoline derivatives |
| AU2022375634A1 (en) | 2021-10-25 | 2024-06-06 | Terns Pharmaceuticals, Inc. | Compounds as glp-1r agonists |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3488353A (en) * | 1967-05-29 | 1970-01-06 | Sterling Drug Inc | New 1-((2-azaindolyl)-lower-alkyl) 4-substituted-piperazines |
| US3678059A (en) * | 1969-10-07 | 1972-07-18 | Ciba Geigy Corp | 3-aminoalkylidene-indazoles |
| US5116846A (en) * | 1990-03-28 | 1992-05-26 | Du Pont Merck Pharmaceutical Company | N-aralkyl piperidine derivatives as psychotropic drugs |
| NZ243065A (en) * | 1991-06-13 | 1995-07-26 | Lundbeck & Co As H | Piperidine derivatives and pharmaceutical compositions |
| FR2692901B1 (fr) * | 1992-06-26 | 1994-08-19 | Cray Valley Sa | Résines et compositions pour la fabrication de matériaux de haut module résistants à la chaleur et articles moulés obtenus à partir de ces matériaux. |
| WO1994020497A1 (en) * | 1993-03-01 | 1994-09-15 | Merck Sharp & Dohme Limited | Pyrrolo-pyridine derivatives |
-
1993
- 1993-03-18 GB GB939305641A patent/GB9305641D0/en active Pending
-
1994
- 1994-03-14 DE DE69419917T patent/DE69419917T2/de not_active Expired - Fee Related
- 1994-03-14 EP EP94909209A patent/EP0701555B1/de not_active Expired - Lifetime
- 1994-03-14 CA CA002156839A patent/CA2156839A1/en not_active Abandoned
- 1994-03-14 AU AU62139/94A patent/AU679214B2/en not_active Ceased
- 1994-03-14 ES ES94909209T patent/ES2133544T3/es not_active Expired - Lifetime
- 1994-03-14 AT AT94909209T patent/ATE182891T1/de active
- 1994-03-14 US US08/530,226 patent/US5665732A/en not_active Expired - Fee Related
- 1994-03-14 WO PCT/GB1994/000503 patent/WO1994021626A1/en active IP Right Grant
- 1994-03-14 JP JP6520765A patent/JPH08507780A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| JPH08507780A (ja) | 1996-08-20 |
| EP0701555B1 (de) | 1999-08-04 |
| GB9305641D0 (en) | 1993-05-05 |
| AU679214B2 (en) | 1997-06-26 |
| AU6213994A (en) | 1994-10-11 |
| DE69419917T2 (de) | 2000-02-24 |
| US5665732A (en) | 1997-09-09 |
| EP0701555A1 (de) | 1996-03-20 |
| ES2133544T3 (es) | 1999-09-16 |
| CA2156839A1 (en) | 1994-09-29 |
| WO1994021626A1 (en) | 1994-09-29 |
| DE69419917D1 (de) | 1999-09-09 |
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