DE69418961D1 - Benzothiazol-derivate, verfahren zur herstellung sowie anwendungen - Google Patents

Benzothiazol-derivate, verfahren zur herstellung sowie anwendungen

Info

Publication number
DE69418961D1
DE69418961D1 DE69418961T DE69418961T DE69418961D1 DE 69418961 D1 DE69418961 D1 DE 69418961D1 DE 69418961 T DE69418961 T DE 69418961T DE 69418961 T DE69418961 T DE 69418961T DE 69418961 D1 DE69418961 D1 DE 69418961D1
Authority
DE
Germany
Prior art keywords
halogen
neurosis
cataract
lower alkyl
applications
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69418961T
Other languages
English (en)
Other versions
DE69418961T2 (de
Inventor
Takema Hase
Takahiro Kumonaka
Chikako Shimizu
Hiroshi Hosono
Tomoji Aotsuka
Yoshiyuki Nakamura
Tetsuo Matsui
Hiromichi Ishikawa
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
WELFIDE CORP., OSAKA, JP SENJU PHARMACEUTICAL CO.,
Original Assignee
Senju Pharmaceutical Co Ltd
Welfide Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Senju Pharmaceutical Co Ltd, Welfide Corp filed Critical Senju Pharmaceutical Co Ltd
Publication of DE69418961D1 publication Critical patent/DE69418961D1/de
Application granted granted Critical
Publication of DE69418961T2 publication Critical patent/DE69418961T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C07C255/01—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms
    • C07C255/24—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms containing cyano groups and singly-bound nitrogen atoms, not being further bound to other hetero atoms, bound to the same saturated acyclic carbon skeleton
    • C07C255/25—Aminoacetonitriles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
    • C07D277/62—Benzothiazoles
    • C07D277/64—Benzothiazoles with only hydrocarbon or substituted hydrocarbon radicals attached in position 2

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Endocrinology (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Emergency Medicine (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DE69418961T 1993-03-26 1994-03-25 Benzothiazol-derivate, verfahren zur herstellung sowie anwendungen Expired - Fee Related DE69418961T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP05090550A JP3126541B2 (ja) 1993-03-26 1993-03-26 ベンゾチアゾール誘導体、その製法及びその用途
PCT/JP1994/000490 WO1994022845A1 (en) 1993-03-26 1994-03-25 Benzothiazole compound, process for producing the same, and use thereof

Publications (2)

Publication Number Publication Date
DE69418961D1 true DE69418961D1 (de) 1999-07-15
DE69418961T2 DE69418961T2 (de) 1999-12-23

Family

ID=14001528

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69418961T Expired - Fee Related DE69418961T2 (de) 1993-03-26 1994-03-25 Benzothiazol-derivate, verfahren zur herstellung sowie anwendungen

Country Status (12)

Country Link
US (1) US5532257A (de)
EP (1) EP0647636B1 (de)
JP (1) JP3126541B2 (de)
KR (1) KR100299558B1 (de)
CN (1) CN1108456A (de)
AT (1) ATE181067T1 (de)
AU (1) AU676894B2 (de)
CA (1) CA2136743A1 (de)
DE (1) DE69418961T2 (de)
ES (1) ES2132394T3 (de)
TW (1) TW245717B (de)
WO (1) WO1994022845A1 (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH05337783A (ja) * 1992-06-08 1993-12-21 Ona Electro Erosion Sa 荷積み荷下ろしパレットのドアの自動開放装置
JPH0782259A (ja) * 1993-09-14 1995-03-28 Senju Pharmaceut Co Ltd スクシンアミド酸誘導体及びそれを含有する糖尿病合併症治療剤
US5700819A (en) * 1994-11-29 1997-12-23 Grelan Pharmaceutical Co., Ltd. 2-substituted benzothiazole derivatives and prophylactic and therapeutic agents for the treatment of diabetic complications
US6121300A (en) * 1998-11-10 2000-09-19 Wagle; Dilip R. Reversing advanced glycosylation cross-links using heterocyclic-substituted thiazolium salts
UA100527C2 (en) * 2007-10-10 2013-01-10 Астразенека Аб Benzothiazoles as ghrelin receptor modulators
US20210347748A1 (en) * 2018-09-25 2021-11-11 Antabio Sas Indane derivatives for use in the treatment of bacterial infection
WO2024003408A1 (en) * 2022-07-01 2024-01-04 Universität Zürich Small-molecule inhibitors of the frs2-fgfr interaction

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3794485A (en) * 1972-06-09 1974-02-26 Polaroid Corp Color diffusion transfer film with incorporated dye and desensitizing agent precursor
JPS5740478A (en) * 1980-08-22 1982-03-06 Ono Pharmaceut Co Ltd Rhodanine derivative, its preparation and aldose reductase inhibitor containing rhodanine derivative
AU602641B2 (en) * 1986-04-17 1990-10-18 Senju Pharmaceutical Co., Ltd. Thiolactam-N-acetic acid derivatives, their production and use
JPH03107970A (ja) * 1989-09-22 1991-05-08 Ricoh Co Ltd 湿式現像の画像形成装置

Also Published As

Publication number Publication date
US5532257A (en) 1996-07-02
EP0647636A4 (de) 1995-04-19
JP3126541B2 (ja) 2001-01-22
WO1994022845A1 (en) 1994-10-13
EP0647636A1 (de) 1995-04-12
ATE181067T1 (de) 1999-06-15
AU6291494A (en) 1994-10-24
CN1108456A (zh) 1995-09-13
EP0647636B1 (de) 1999-06-09
DE69418961T2 (de) 1999-12-23
KR950701627A (ko) 1995-04-28
KR100299558B1 (ko) 2001-11-22
AU676894B2 (en) 1997-03-27
CA2136743A1 (en) 1994-10-13
JPH06279423A (ja) 1994-10-04
ES2132394T3 (es) 1999-08-16
TW245717B (de) 1995-04-21

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: WELFIDE CORP., OSAKA, JP SENJU PHARMACEUTICAL CO.,

8339 Ceased/non-payment of the annual fee