DE69409237T2 - Orale, pharmazeutische zusammensetzungen das ein protein oder peptide, eine antikoerper und polymerkugeln enthalten - Google Patents
Orale, pharmazeutische zusammensetzungen das ein protein oder peptide, eine antikoerper und polymerkugeln enthaltenInfo
- Publication number
- DE69409237T2 DE69409237T2 DE69409237T DE69409237T DE69409237T2 DE 69409237 T2 DE69409237 T2 DE 69409237T2 DE 69409237 T DE69409237 T DE 69409237T DE 69409237 T DE69409237 T DE 69409237T DE 69409237 T2 DE69409237 T2 DE 69409237T2
- Authority
- DE
- Germany
- Prior art keywords
- peptide
- protein
- antibody
- pharmaceutical compositions
- oral
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/167—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/69—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
- A61K47/6943—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit the form being a pill, a tablet, a lozenge or a capsule
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB939311454A GB9311454D0 (en) | 1993-06-03 | 1993-06-03 | Pharmaceutical compositions |
| PCT/GB1994/001201 WO1994028879A1 (en) | 1993-06-03 | 1994-06-02 | Oral pharmaceutical compositions comprising a protein or peptide, an antibody and polymeric beads |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE69409237D1 DE69409237D1 (de) | 1998-04-30 |
| DE69409237T2 true DE69409237T2 (de) | 1998-10-29 |
Family
ID=10736565
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE69409237T Expired - Fee Related DE69409237T2 (de) | 1993-06-03 | 1994-06-02 | Orale, pharmazeutische zusammensetzungen das ein protein oder peptide, eine antikoerper und polymerkugeln enthalten |
Country Status (9)
| Country | Link |
|---|---|
| EP (1) | EP0707473B1 (de) |
| AT (1) | ATE164311T1 (de) |
| AU (1) | AU6804394A (de) |
| DE (1) | DE69409237T2 (de) |
| DK (1) | DK0707473T3 (de) |
| ES (1) | ES2117272T3 (de) |
| GB (1) | GB9311454D0 (de) |
| WO (1) | WO1994028879A1 (de) |
| ZA (1) | ZA943920B (de) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK0991403T3 (da) | 1997-01-30 | 2003-07-28 | Chiron Corp | Anvendelse af mikropartikler med adsorberet antigen til stimulering af immunresponser |
| EP1275380A1 (de) * | 1997-01-30 | 2003-01-15 | Chiron Corporation | Verwendung von Mikropartikeln mit adsorbiertem Antigen zur Stimulierung der Immunabwehr |
| US6884435B1 (en) | 1997-01-30 | 2005-04-26 | Chiron Corporation | Microparticles with adsorbent surfaces, methods of making same, and uses thereof |
| IT1291559B1 (it) | 1997-04-14 | 1999-01-11 | Univ Degli Studi Milano | Uso di microparticelle su cui sono stati adsorbiti una proteina ed un anticorpo per preparare una composizione farmaceutica somministrabile |
| CA2420621C (en) | 2000-09-28 | 2011-05-24 | Chiron Corporation | Microparticle compositions and methods for the manufacture thereof |
| EP2267032A3 (de) | 2002-11-08 | 2011-11-09 | Ablynx N.V. | Verfahren zur Verabreichung therapeutischer Polypeptide und Polypeptide dafür |
| WO2004041865A2 (en) | 2002-11-08 | 2004-05-21 | Ablynx N.V. | Stabilized single domain antibodies |
| CN101412759A (zh) | 2003-01-10 | 2009-04-22 | 埃博灵克斯股份有限公司 | 治疗性多肽,其同源物、其片段及其在调节血小板介导的聚集方面的应用 |
| WO2005020964A1 (en) | 2003-06-02 | 2005-03-10 | Chiron Corporation | Immunogenic compositions based on microparticles comprising adsorbed toxoid and a polysaccharide-containing antigen |
| DK1687338T3 (da) | 2003-11-07 | 2011-02-07 | Ablynx Nv | Camelidae enkeltdomæne-antistoffer VHH, der er rettet mod epidermal vækstfaktor-receptor og anvendelser deraf |
| EP1888640B1 (de) | 2005-05-18 | 2012-03-14 | Ablynx N.V. | Verbesserte nanokörper gegen tumornekrosefaktor-alpha |
| PL3415535T3 (pl) | 2005-05-20 | 2021-06-14 | Ablynx N.V. | Ulepszone Nanociała TM do leczenia zaburzeń, w których pośredniczy agregacja |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2595826B1 (fr) * | 1986-03-13 | 1990-09-07 | Lurhuma Zirimwabagabo | Produit d'immuno-essai, son procede de preparation, son utilisation, complexe immunogene le comportant et utilisation de ce complexe |
| NZ242220A (en) * | 1991-04-02 | 1994-04-27 | Biotech Australia Pty Ltd | Complex for oral delivery of a substance to the circulatory or lymphatic drainage system comprising microparticle coupled to at least one carrier, the substance being encapsulated by the microparticle |
-
1993
- 1993-06-03 GB GB939311454A patent/GB9311454D0/en active Pending
-
1994
- 1994-06-02 AU AU68043/94A patent/AU6804394A/en not_active Abandoned
- 1994-06-02 DK DK94916352T patent/DK0707473T3/da active
- 1994-06-02 EP EP94916352A patent/EP0707473B1/de not_active Expired - Lifetime
- 1994-06-02 WO PCT/GB1994/001201 patent/WO1994028879A1/en active IP Right Grant
- 1994-06-02 DE DE69409237T patent/DE69409237T2/de not_active Expired - Fee Related
- 1994-06-02 ES ES94916352T patent/ES2117272T3/es not_active Expired - Lifetime
- 1994-06-02 AT AT94916352T patent/ATE164311T1/de not_active IP Right Cessation
- 1994-06-03 ZA ZA943920A patent/ZA943920B/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| DE69409237D1 (de) | 1998-04-30 |
| EP0707473B1 (de) | 1998-03-25 |
| ZA943920B (en) | 1995-12-04 |
| ES2117272T3 (es) | 1998-08-01 |
| WO1994028879A1 (en) | 1994-12-22 |
| GB9311454D0 (en) | 1993-07-21 |
| DK0707473T3 (da) | 1999-01-04 |
| ATE164311T1 (de) | 1998-04-15 |
| EP0707473A1 (de) | 1996-04-24 |
| AU6804394A (en) | 1995-01-03 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition | ||
| 8339 | Ceased/non-payment of the annual fee |