DK0707473T3 - Orale farmaceutiske præparater omfattende et protein eller et peptid, et antistof og polymerkugler - Google Patents

Orale farmaceutiske præparater omfattende et protein eller et peptid, et antistof og polymerkugler

Info

Publication number
DK0707473T3
DK0707473T3 DK94916352T DK94916352T DK0707473T3 DK 0707473 T3 DK0707473 T3 DK 0707473T3 DK 94916352 T DK94916352 T DK 94916352T DK 94916352 T DK94916352 T DK 94916352T DK 0707473 T3 DK0707473 T3 DK 0707473T3
Authority
DK
Denmark
Prior art keywords
peptide
protein
antibody
pharmaceutical compositions
polymer beads
Prior art date
Application number
DK94916352T
Other languages
Danish (da)
English (en)
Inventor
Michael Waddington Smith
Original Assignee
Babraham Inst
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Babraham Inst filed Critical Babraham Inst
Application granted granted Critical
Publication of DK0707473T3 publication Critical patent/DK0707473T3/da

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/167Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/69Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
    • A61K47/6943Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit the form being a pill, a tablet, a lozenge or a capsule
DK94916352T 1993-06-03 1994-06-02 Orale farmaceutiske præparater omfattende et protein eller et peptid, et antistof og polymerkugler DK0707473T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB939311454A GB9311454D0 (en) 1993-06-03 1993-06-03 Pharmaceutical compositions
PCT/GB1994/001201 WO1994028879A1 (en) 1993-06-03 1994-06-02 Oral pharmaceutical compositions comprising a protein or peptide, an antibody and polymeric beads

Publications (1)

Publication Number Publication Date
DK0707473T3 true DK0707473T3 (da) 1999-01-04

Family

ID=10736565

Family Applications (1)

Application Number Title Priority Date Filing Date
DK94916352T DK0707473T3 (da) 1993-06-03 1994-06-02 Orale farmaceutiske præparater omfattende et protein eller et peptid, et antistof og polymerkugler

Country Status (9)

Country Link
EP (1) EP0707473B1 (de)
AT (1) ATE164311T1 (de)
AU (1) AU6804394A (de)
DE (1) DE69409237T2 (de)
DK (1) DK0707473T3 (de)
ES (1) ES2117272T3 (de)
GB (1) GB9311454D0 (de)
WO (1) WO1994028879A1 (de)
ZA (1) ZA943920B (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK0991403T3 (da) 1997-01-30 2003-07-28 Chiron Corp Anvendelse af mikropartikler med adsorberet antigen til stimulering af immunresponser
EP1275380A1 (de) * 1997-01-30 2003-01-15 Chiron Corporation Verwendung von Mikropartikeln mit adsorbiertem Antigen zur Stimulierung der Immunabwehr
US6884435B1 (en) 1997-01-30 2005-04-26 Chiron Corporation Microparticles with adsorbent surfaces, methods of making same, and uses thereof
IT1291559B1 (it) 1997-04-14 1999-01-11 Univ Degli Studi Milano Uso di microparticelle su cui sono stati adsorbiti una proteina ed un anticorpo per preparare una composizione farmaceutica somministrabile
CA2420621C (en) 2000-09-28 2011-05-24 Chiron Corporation Microparticle compositions and methods for the manufacture thereof
EP2267032A3 (de) 2002-11-08 2011-11-09 Ablynx N.V. Verfahren zur Verabreichung therapeutischer Polypeptide und Polypeptide dafür
WO2004041865A2 (en) 2002-11-08 2004-05-21 Ablynx N.V. Stabilized single domain antibodies
CN101412759A (zh) 2003-01-10 2009-04-22 埃博灵克斯股份有限公司 治疗性多肽,其同源物、其片段及其在调节血小板介导的聚集方面的应用
WO2005020964A1 (en) 2003-06-02 2005-03-10 Chiron Corporation Immunogenic compositions based on microparticles comprising adsorbed toxoid and a polysaccharide-containing antigen
DK1687338T3 (da) 2003-11-07 2011-02-07 Ablynx Nv Camelidae enkeltdomæne-antistoffer VHH, der er rettet mod epidermal vækstfaktor-receptor og anvendelser deraf
EP1888640B1 (de) 2005-05-18 2012-03-14 Ablynx N.V. Verbesserte nanokörper gegen tumornekrosefaktor-alpha
PL3415535T3 (pl) 2005-05-20 2021-06-14 Ablynx N.V. Ulepszone Nanociała TM do leczenia zaburzeń, w których pośredniczy agregacja

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2595826B1 (fr) * 1986-03-13 1990-09-07 Lurhuma Zirimwabagabo Produit d'immuno-essai, son procede de preparation, son utilisation, complexe immunogene le comportant et utilisation de ce complexe
NZ242220A (en) * 1991-04-02 1994-04-27 Biotech Australia Pty Ltd Complex for oral delivery of a substance to the circulatory or lymphatic drainage system comprising microparticle coupled to at least one carrier, the substance being encapsulated by the microparticle

Also Published As

Publication number Publication date
DE69409237D1 (de) 1998-04-30
EP0707473B1 (de) 1998-03-25
ZA943920B (en) 1995-12-04
ES2117272T3 (es) 1998-08-01
WO1994028879A1 (en) 1994-12-22
GB9311454D0 (en) 1993-07-21
ATE164311T1 (de) 1998-04-15
EP0707473A1 (de) 1996-04-24
DE69409237T2 (de) 1998-10-29
AU6804394A (en) 1995-01-03

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