DE69333020D1 - Metallinduzierte kreuzkopplung mit ringmetallisierten porphyrinen - Google Patents

Metallinduzierte kreuzkopplung mit ringmetallisierten porphyrinen

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Publication number
DE69333020D1
DE69333020D1 DE69333020T DE69333020T DE69333020D1 DE 69333020 D1 DE69333020 D1 DE 69333020D1 DE 69333020 T DE69333020 T DE 69333020T DE 69333020 T DE69333020 T DE 69333020T DE 69333020 D1 DE69333020 D1 DE 69333020D1
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Germany
Prior art keywords
porphyrines
metalized
coupling
ring
metal
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69333020T
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English (en)
Other versions
DE69333020T2 (de
Inventor
J Therien
G Dimagno
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University of Pennsylvania Penn
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University of Pennsylvania Penn
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Filing date
Publication date
Priority claimed from US08/064,468 external-priority patent/US5493017A/en
Application filed by University of Pennsylvania Penn filed Critical University of Pennsylvania Penn
Application granted granted Critical
Publication of DE69333020D1 publication Critical patent/DE69333020D1/de
Publication of DE69333020T2 publication Critical patent/DE69333020T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/0057—Photodynamic therapy with a photosensitizer, i.e. agent able to produce reactive oxygen species upon exposure to light or radiation, e.g. UV or visible light; photocleavage of nucleic acids with an agent
    • A61K41/0071—PDT with porphyrins having exactly 20 ring atoms, i.e. based on the non-expanded tetrapyrrolic ring system, e.g. bacteriochlorin, chlorin-e6, or phthalocyanines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/555—Heterocyclic compounds containing heavy metals, e.g. hemin, hematin, melarsoprol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
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    • A61K47/545—Heterocyclic compounds
    • A61K47/546—Porphyrines; Porphyrine with an expanded ring system, e.g. texaphyrine
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    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/0474—Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group
    • A61K51/0485—Porphyrins, texaphyrins wherein the nitrogen atoms forming the central ring system complex the radioactive metal
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    • B01J31/181—Cyclic ligands, including e.g. non-condensed polycyclic ligands, comprising at least one complexing nitrogen atom as ring member, e.g. pyridine
    • B01J31/1815—Cyclic ligands, including e.g. non-condensed polycyclic ligands, comprising at least one complexing nitrogen atom as ring member, e.g. pyridine with more than one complexing nitrogen atom, e.g. bipyridyl, 2-aminopyridine
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    • B01J31/24—Phosphines, i.e. phosphorus bonded to only carbon atoms, or to both carbon and hydrogen atoms, including e.g. sp2-hybridised phosphorus compounds such as phosphabenzene, phosphole or anionic phospholide ligands
    • B01J31/2404—Cyclic ligands, including e.g. non-condensed polycyclic ligands, the phosphine-P atom being a ring member or a substituent on the ring
    • B01J31/2409—Cyclic ligands, including e.g. non-condensed polycyclic ligands, the phosphine-P atom being a ring member or a substituent on the ring with more than one complexing phosphine-P atom
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    • C07C29/48—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by oxidation reactions with formation of hydroxy groups
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    • C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
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    • C07D207/33—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with substituted hydrocarbon radicals, directly attached to ring carbon atoms
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    • C07D207/32—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
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    • B01J2531/48—Zirconium
    • B—PERFORMING OPERATIONS; TRANSPORTING
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    • B01J2531/00—Additional information regarding catalytic systems classified in B01J31/00
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DE69333020T 1992-08-14 1993-08-16 Metallinduzierte kreuzkopplung mit ringmetallisierten porphyrinen Expired - Lifetime DE69333020T2 (de)

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US07929943 US5371199B1 (en) 1992-08-14 1992-08-14 Substituted porphyrins porphyrin-containing polymers and synthetic methods therefor
US08/064,468 US5493017A (en) 1992-08-14 1993-05-20 Ring-metalated porphyrins
US64468 1993-05-20
PCT/US1993/007686 WO1994004614A1 (en) 1992-08-14 1993-08-16 Metal-mediated cross-coupling with ring-metalated porphyrins

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Families Citing this family (67)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5457183A (en) * 1989-03-06 1995-10-10 Board Of Regents, The University Of Texas System Hydroxylated texaphyrins
US5599923A (en) * 1989-03-06 1997-02-04 Board Of Regents, University Of Tx Texaphyrin metal complexes having improved functionalization
US5543514A (en) * 1989-12-21 1996-08-06 Board Of Regents, The University Of Texas System Water-soluble sapphyrins
US5457195A (en) * 1989-12-21 1995-10-10 Board Of Regents, The University Of Texas System Sapphyrin derivatives and conjugates
US5594136A (en) * 1989-12-21 1997-01-14 Pharmacyclics, Inc. Texaphyrin solid supports and devices
US5565552A (en) * 1992-01-21 1996-10-15 Pharmacyclics, Inc. Method of expanded porphyrin-oligonucleotide conjugate synthesis
US5595726A (en) * 1992-01-21 1997-01-21 Pharmacyclics, Inc. Chromophore probe for detection of nucleic acid
US5607924A (en) * 1992-01-21 1997-03-04 Pharmacyclics, Inc. DNA photocleavage using texaphyrins
US5763172A (en) * 1992-01-21 1998-06-09 Board Of Regents, The University Of Texas System Method of phosphate ester hydrolysis
US5888997A (en) * 1994-04-14 1999-03-30 Pharmacyclics, Inc. Radiation sensitization using texaphyrins
US5371199B1 (en) * 1992-08-14 1995-12-26 Univ Pennsylvania Substituted porphyrins porphyrin-containing polymers and synthetic methods therefor
US5817830A (en) * 1992-08-14 1998-10-06 Trustees Of The University Of Pennsylvania Pyrrolic compounds
US5599924A (en) * 1992-08-14 1997-02-04 Trustees Of The University Of Pennsylvania Electron-deficient porphyrins and processes and intermediates for preparing same
US5783306A (en) * 1992-08-14 1998-07-21 Trustees Of The University Of Pennsylvania Hyperpolarizable compounds and devices fabricated therefrom
DE4232925A1 (de) * 1992-09-28 1994-03-31 Diagnostikforschung Inst 3-,8-substituierte Deuteroporphyrinderivate, diese enthaltende pharmazeutische Mittel und Verfahren zu ihrer Herstellung
US5798491A (en) * 1993-06-09 1998-08-25 Board Of Regents, The University Of Texas System Multi-mechanistic chemical cleavage using certain metal complexes
US6127356A (en) * 1993-10-15 2000-10-03 Duke University Oxidant scavengers
US5994339A (en) * 1993-10-15 1999-11-30 University Of Alabama At Birmingham Research Foundation Oxidant scavengers
US5608054A (en) * 1993-12-29 1997-03-04 Sun Company, Inc. (R&M) Porphyrins and metal complexes thereof having haloalkyl side chains
US5969111A (en) * 1994-04-14 1999-10-19 Board Of Regents, The University Of Texas System Texaphyrins substituted with imidazole are provided
WO1996009053A1 (en) * 1994-09-20 1996-03-28 Duke University Oxidoreductase activity of manganic porphyrins
US5633354A (en) * 1994-09-21 1997-05-27 Pharmacyclics, Inc. Phosphoramidite derivatives of texaphyrins
US5837866A (en) * 1994-09-21 1998-11-17 Board Of Regents, The University Of Texas Phosphoramidite derivatives of macrocycles
US5591422A (en) * 1995-06-02 1997-01-07 Pharmacyclics, Inc. Texaphyrin complexes having improved functionalization
US5714328A (en) * 1995-06-07 1998-02-03 Board Of Regents, The University Of Texas System RNA photocleavage using texaphyrins
GB9616353D0 (en) * 1996-08-03 1996-09-11 Secr Defence Metallo-porphyrins
US6124452A (en) * 1997-12-19 2000-09-26 University Of Nebraska-Lincoln Octafluoro-meso-tetraarylporphyrins and methods for making these compounds
CA2309154C (en) 1997-11-03 2010-02-16 Duke University Substituted porphyrins
ES2257858T3 (es) 1998-04-24 2006-08-01 Duke University Porfirinas sustituidas.
AU765509B2 (en) 1998-08-28 2003-09-18 Destiny Pharma Limited Porphyrin derivatives, their use in photodynamic therapy and medical devices containing them
EP1616869B1 (de) 1999-01-25 2012-04-04 National Jewish Health Substituierte Porphyrine und deren therapeutische Verwendung
AU3503200A (en) * 1999-02-26 2000-09-14 Advanced Research And Technology Institute, Inc. Compounds, compositions, and methods for photodynamic therapy
US6828439B1 (en) 1999-02-26 2004-12-07 Advanced Research And Technology Institute, Inc. Compounds, composition, and methods for photodynamic therapy
US6765092B2 (en) * 2000-07-21 2004-07-20 North Carolina State University Regioisomerically pure oxochlorins and methods of synthesis
US6603070B2 (en) * 2000-07-21 2003-08-05 North Carolina State University Convergent synthesis of multiporphyrin light-harvesting rods
US7211603B1 (en) 2000-09-25 2007-05-01 Indiana University Research And Technology Corporation Enediyne compounds and methods related thereto
US6514995B1 (en) 2000-09-25 2003-02-04 Advanced Research And Technology Institute, Inc. Enediyne compounds and methods related thereto
WO2002104072A2 (en) * 2001-02-26 2002-12-27 The Trustees Of The University Of Pennsylvania Emissive multichromophoric systems
GB0115201D0 (en) * 2001-06-21 2001-08-15 Univ Manchester Organic microporous materials
DE60233163D1 (de) * 2001-12-06 2009-09-10 Cornell Res Foundation Inc Katalytische carbonylierung von drei- und viergliedrigen heterocyklen
US20040067198A1 (en) * 2002-02-26 2004-04-08 Therien Michael J Emissive multichromophoric systems
US7445845B2 (en) * 2002-03-28 2008-11-04 The Trustees Of The University Of Pennsylvania Synthesis, spectroscopy, photophysics of multi-chromophoric ZN(II) group 8 metal complexes
US7375216B2 (en) * 2002-06-04 2008-05-20 Infacare Pharmaceutical Corporation Preparation of metal mesoporphyrin compounds
CA2487426C (en) 2002-06-04 2010-09-07 Wellspring Pharmaceutical Corporation Preparation of metal mesoporphyrin halide compounds
US7485721B2 (en) 2002-06-07 2009-02-03 Duke University Substituted porphyrins
GB2397067B (en) 2002-12-23 2005-05-11 Destiny Pharma Ltd Porphin & azaporphin derivatives with at least one cationic-nitrogen-containing meso-substituent for use in photodynamic therapy & in vitro sterilisation
JP3760265B2 (ja) * 2003-02-06 2006-03-29 独立行政法人科学技術振興機構 キラル化合物の絶対配置決定方法
US7884280B2 (en) * 2003-05-27 2011-02-08 North Carolina State University Stepwise fabrication of molecular-based, cross linked, light harvesting arrays
US7682603B2 (en) * 2003-07-25 2010-03-23 The Trustees Of The University Of Pennsylvania Polymersomes incorporating highly emissive probes
GB2415372A (en) 2004-06-23 2005-12-28 Destiny Pharma Ltd Non photodynamical or sonodynamical antimicrobial use of porphyrins and azaporphyrins containing at least one cationic-nitrogen-containing substituent
US7378520B2 (en) * 2004-07-08 2008-05-27 North Carolina State University Synthesis of porphyrins designed for attachment to electroactive surfaces via one or more carbon tethers
US20060222668A1 (en) * 2005-04-01 2006-10-05 Wellspring Pharmaceutical Corporation Stannsoporfin compositions, drug products and methods of manufacture
PL2079472T3 (pl) 2006-10-04 2012-01-31 Infacare Pharmaceutical Corp Wytwarzanie stannsoporfiny o wysokiej czystości na dużą skalę
KR20090079916A (ko) * 2006-10-04 2009-07-22 인파케어 파마슈티칼 코포레이션 저 투여량의 스탄소포르핀을 이용한 유아 고빌리루빈혈증의 치료
WO2008144750A1 (en) * 2007-05-21 2008-11-27 Plextronics, Inc. Porphyrin and conductive polymer compositions for use in solid-state electronic devices
US11382895B2 (en) 2008-05-23 2022-07-12 National Jewish Health Methods for treating injury associated with exposure to an alkylating species
EP2230242B1 (de) 2009-03-16 2013-08-14 Johannes Kepler Universität Synthese von neuen asymmetrisch mesosubstituierten wasserlöslichen, als zytostatische Mittel wirkenden Porphyrinen
CN102686592B (zh) * 2010-01-30 2013-11-27 海洋王照明科技股份有限公司 含芴卟啉-蒽共聚物、其制备方法和应用
WO2011143806A1 (zh) * 2010-05-18 2011-11-24 海洋王照明科技股份有限公司 含喹喔啉单元卟啉共聚物及其制备方法和应用
WO2012034267A1 (zh) * 2010-09-13 2012-03-22 海洋王照明科技股份有限公司 硅芴金属卟啉-苯有机半导体材料及其制备方法和应用
DK2691398T3 (en) 2011-03-30 2017-01-16 Infacare Pharmaceutical Corp Methods for synthesizing metal mesoporphyrins
CN104364292B (zh) 2012-04-13 2018-02-02 韦克森林大学 低带隙结合聚合组合物及其应用
JP5906522B2 (ja) * 2012-05-18 2016-04-20 新日鉄住金化学株式会社 フタロシアニン色素並びにフタロシアニン色素を用いた色素増感太陽電池及び光電変換素子
US9090742B2 (en) 2013-06-28 2015-07-28 Sharp Laboratories Of America, Inc. Facile synthesis of metalloporphyrin polymers
CN109867770B (zh) * 2019-03-11 2021-11-30 吉林大学 基于卟啉官能团的共轭微孔聚合物及其制备方法与应用
CN110964179B (zh) * 2019-12-19 2022-06-21 湘潭大学 一种卟啉聚合物及其制备方法和在正极材料中的应用
CN113698579B (zh) * 2021-07-23 2023-09-01 西北民族大学 卟啉型共轭微孔聚合物及其合成方法和应用

Family Cites Families (65)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3579533A (en) * 1968-03-18 1971-05-18 Antioch College Preparation of porphin,substituted porphin and metal chelates thereof
US3687863A (en) * 1970-05-25 1972-08-29 Gen Telephone & Elect Optical filters containing tetraphenyl-porphins and method of making same
US3899334A (en) * 1971-10-18 1975-08-12 Monsanto Co Photoimaging procedures and compositions
US3897255A (en) * 1971-10-18 1975-07-29 Monsanto Co Photoimaging compositions comprising complex of prophyrin-SO{HD 2 {B as sensitizer
US4104466A (en) * 1974-03-13 1978-08-01 Eishun Tsuchida Polymeric metal complex and method of manufacturing the same
US4360703A (en) * 1981-04-28 1982-11-23 National Research Council Of Canada Photovoltaic cell having P-N junction of organic materials
US4649151A (en) * 1982-09-27 1987-03-10 Health Research, Inc. Drugs comprising porphyrins
CA1258313A (en) * 1983-09-26 1989-08-08 Branimir Simic-Glavaski Molecular electro-optical transistor and switch
DE3410789A1 (de) * 1984-03-23 1985-09-26 Siemens AG, 1000 Berlin und 8000 München Verfahren zur orientierung einer fluessigkristallinen substanz bezueglich einer unterlage
US4565799A (en) * 1984-07-12 1986-01-21 The Standard Oil Company (Ohio) Ionically polymer-bound transition metal complex for photochemical conversion of light energy
IN165525B (de) * 1984-07-23 1989-11-04 Shinetsu Chemical Co
US5242892A (en) * 1984-07-27 1993-09-07 The Board Of Trustees Of The University Of Illinois Chlorophyll biosynthesis modulators
US4986256A (en) * 1985-02-28 1991-01-22 The United States Of America As Represented By The Department Of Health And Human Services Use of paramagnetic metalloporphyrins as contrast agents for tumors in MRI imaging
US4657902A (en) * 1985-03-25 1987-04-14 The Rockefeller University Therapeutic use of tin mesoporphyrin
EP0227815A4 (de) * 1985-07-03 1988-06-23 Internat Biomedics Inc Messverfahren für die sauerstoffkonzentration.
JPS62180263A (ja) * 1986-02-04 1987-08-07 Terumo Corp 酸素センサ−
US4668670A (en) * 1986-06-20 1987-05-26 The Rockefeller University Tin diiododeuteroporphyrin and therapeutic use thereof
US4792836A (en) * 1986-12-01 1988-12-20 The United States Of America As Represented By The Secretary Of The Air Force Ion-sensitive photodetector
US4895682A (en) * 1987-01-02 1990-01-23 Sun Refining And Marketing Copany Hydrocarbon oxidations catalyzed by azide-activated metal coordination complexes
US4892941A (en) * 1987-04-17 1990-01-09 Dolphin David H Porphyrins
US5051337A (en) * 1987-06-10 1991-09-24 Director-General Of Agency Of Industrial Science And Technology Optical recording material
CA1341460C (en) * 1988-01-11 2004-10-19 The Medical College Of Ohio Production and use of porphyrin derivatives and of compositions containing such derivates
EP0340968A3 (de) * 1988-04-30 1992-05-06 Seiko Epson Corporation Dünnschichtvorrichtung und Herstellungsverfahren derselben
JPH03504450A (ja) * 1988-05-09 1991-10-03 ザ・パブリツク・ヘルス・ラボラタリイ・サーヴイス・ボード 脱ハロゲン化における金属キレート錯体の使用
US5192788A (en) * 1988-05-23 1993-03-09 Georgia State University Foundation, Inc. Porphyrin antiviral compositions
DE3827640A1 (de) * 1988-08-16 1990-02-22 Basf Ag Elektrisch leitfaehige copolymerisate auf der basis von verbindungen mit porphyrinstruktur
US5091502A (en) * 1988-09-23 1992-02-25 General Petrochemical Industries Ltd Tetraketone porphyrin monomers and the porphyrin-based polymers thereof
GB8827123D0 (en) * 1988-11-21 1988-12-29 Atomic Energy Authority Uk Supported oxidation catalyst
US5106753A (en) * 1989-01-26 1992-04-21 Miles Inc. Method for determining manganese level in blood using a porphyrin composition
DE69020380T2 (de) * 1989-02-22 1995-12-07 Unilever Nv Metallporphyrine zur Verwendung als Bleichkatalysatoren.
US5041078A (en) * 1989-03-06 1991-08-20 Baylor Research Foundation, A Nonprofit Corporation Of The State Of Texas Photodynamic viral deactivation with sapphyrins
JP2752687B2 (ja) * 1989-03-29 1998-05-18 三菱電機株式会社 ヘテロ分子接合に基づく光素子
PT93772A (pt) * 1989-04-17 1991-01-08 Searle & Co Processo para a preparacao de composicoes para o tratamento de neoplasias, contendo um agente anti-neoplastico, por exemplo doxorubicina e um agente protector para reduzir os efeitos secundarios, por exemplo carbetimer
US5171741A (en) * 1989-04-21 1992-12-15 Health Research, Inc. Bacteriochlorophyll-a derivatives useful in photodynamic therapy
AU634307B2 (en) * 1989-09-25 1993-02-18 Rockefeller University, The Orally administered porphyrins to control intestinal iron absorption
US4970348A (en) * 1989-11-06 1990-11-13 Sun Refining And Marketing Company Chromium halogenated coordination complexes for the oxidation of butane to methylethylketone
GB2239705B (en) * 1989-11-08 1993-05-12 Nat Res Dev Gas sensors and compounds suitable therefor
EP0428214B1 (de) * 1989-11-13 1995-03-29 Agfa-Gevaert N.V. Elektrophotographisches Aufzeichnungsmaterial
US5102625A (en) * 1990-02-16 1992-04-07 Boc Health Care, Inc. Apparatus for monitoring a chemical concentration
ATE206395T1 (de) * 1990-05-15 2001-10-15 Hyperion Inc Fluoreszierende porphyrin- und fluoreszierende phthalocyanin-polyethylenglykol-, polyol- und saccharidderivate als fluoreszierende sonden
WO1991018007A1 (en) * 1990-05-15 1991-11-28 Diatron Corporation Phthalocyanatopolyethylene glycol, and phthalocyanato saccharides as fluorescent digoxin reagents
US5164944A (en) * 1990-06-08 1992-11-17 Unisys Corporation Method and apparatus for effecting multiple error correction in a computer memory
US5364654A (en) * 1990-06-14 1994-11-15 Idemitsu Kosan Co., Ltd. Process for production of a thin film electrode and an electroluminescence device
JP2533014B2 (ja) * 1990-06-30 1996-09-11 ユニオン・カーバイド・インダストリアル・ガセズ・テクノロジー・コーポレーション 酸素透過高分子膜
DE69130361T2 (de) * 1990-07-06 1999-06-17 Univ Australian Polymerisierbare porphyrine
NO913150L (no) * 1990-08-16 1992-02-17 Sun Refining & Marketing Katalysator.
US5202317A (en) * 1990-09-13 1993-04-13 The Regents Of The University Of California Synthetic drug molecules that mimic metalloenzymes
CA2093361C (en) * 1990-10-05 2002-04-23 Michel Ringuet Porphyrin derivative
EP0480361A3 (en) * 1990-10-11 1992-11-25 Takeda Chemical Industries, Ltd. Quantitation by chemiluminescence using photosenstive substance
US5149801A (en) * 1990-11-21 1992-09-22 The Regents Of The University Of California Boronated porphyrin compounds
CA2056245A1 (en) * 1990-12-07 1992-06-08 Paul E. Ellis, Jr. Process for preparing perhaloporphyrin complexes
US5120453A (en) * 1990-12-24 1992-06-09 Uop Oxidative removal of cyanide from aqueous streams
GB9103991D0 (en) * 1991-02-26 1991-04-10 Nat Res Dev Molecular electronic devices
US5169944A (en) * 1991-04-12 1992-12-08 Board Of Regents Of The University Of Washington Methods and compositions for the enteral administration of hepatobiliary MRI contrast agents
US5120886A (en) * 1991-07-09 1992-06-09 Sun Refining And Marketing Company Decomposition of organic hydroperoxides
US5200481A (en) * 1991-07-15 1993-04-06 Hoechst Celanese Corp. Tetraazaporphyrin monomers and polymers
US5103027A (en) * 1991-07-23 1992-04-07 Arco Chemical Technology, L.P. Olefin expoxidation using an oxorhenium porphyrin complex catalyst and an organic hydroperoxide
US5120882A (en) * 1991-09-12 1992-06-09 Sun Refining And Marketing Company Nitrated metalloporphyrins as catalysts for alkane oxidation
US5280115A (en) * 1991-09-12 1994-01-18 Sun Company, Inc. (R&M) Nitrated metalloporphyrins as catalysts for alkane oxidation
US5212300A (en) * 1991-09-12 1993-05-18 Sun Company, Inc. (R&M) Cyano- and polycyanometallo-porphyrins as catalysts for alkane oxidation
US5118886A (en) * 1991-09-12 1992-06-02 Sun Refining And Marketing Company Cyano- and polycyanometalloporphyrins as catalysts for alkane oxidation
US5252730A (en) * 1992-04-10 1993-10-12 Northrop Corporation Polymer composition having intense magnetic properties and method for preparation thereof
US5244914A (en) * 1992-04-27 1993-09-14 American Cyanamid Company Stable porfimer sodium compositions and methods for their manufacture
US5371199B1 (en) * 1992-08-14 1995-12-26 Univ Pennsylvania Substituted porphyrins porphyrin-containing polymers and synthetic methods therefor
US5675001A (en) * 1995-03-14 1997-10-07 Hoffman/Barrett, L.L.C. Heteroatom-functionalized porphyrazines and multimetallic complexes and polymers derived therefrom

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DE69333020T2 (de) 2004-02-26
AU5013993A (en) 1994-03-15
JP2002515001A (ja) 2002-05-21
CA2142280A1 (en) 1994-03-03
US5986090A (en) 1999-11-16
DK0656037T3 (da) 2003-10-06
US5371199B1 (en) 1995-12-26
EP0656037A4 (de) 1997-07-30
US5371199A (en) 1994-12-06
CA2142280C (en) 2007-03-20
EP0656037A1 (de) 1995-06-07
WO1994004614A1 (en) 1994-03-03
EP0656037B1 (de) 2003-06-04
US5756723A (en) 1998-05-26

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