DE69332610D1 - Screeningverfahren für das down-syndrom unter verwendung von getrockneten blutproben - Google Patents

Screeningverfahren für das down-syndrom unter verwendung von getrockneten blutproben

Info

Publication number
DE69332610D1
DE69332610D1 DE69332610T DE69332610T DE69332610D1 DE 69332610 D1 DE69332610 D1 DE 69332610D1 DE 69332610 T DE69332610 T DE 69332610T DE 69332610 T DE69332610 T DE 69332610T DE 69332610 D1 DE69332610 D1 DE 69332610D1
Authority
DE
Germany
Prior art keywords
dried blood
trisomy
hcg
blood samples
down syndrome
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69332610T
Other languages
English (en)
Other versions
DE69332610T2 (de
Inventor
James N Marci
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Application granted granted Critical
Publication of DE69332610D1 publication Critical patent/DE69332610D1/de
Publication of DE69332610T2 publication Critical patent/DE69332610T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/74Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
    • G01N33/76Human chorionic gonadotropin including luteinising hormone, follicle stimulating hormone, thyroid stimulating hormone or their receptors
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00Chemistry: analytical and immunological testing
    • Y10S436/815Test for named compound or class of compounds
    • Y10S436/817Steroids or hormones
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00Chemistry: analytical and immunological testing
    • Y10S436/815Test for named compound or class of compounds
    • Y10S436/817Steroids or hormones
    • Y10S436/818Human chorionic gonadotropin

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Endocrinology (AREA)
  • Hematology (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Reproductive Health (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Cell Biology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
DE69332610T 1992-08-07 1993-08-06 Screeningverfahren für das down-syndrom unter verwendung von getrockneten blutproben Expired - Lifetime DE69332610T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US07/925,683 US5252489A (en) 1989-01-17 1992-08-07 Down syndrome screening method utilizing dried blood samples
PCT/US1993/007507 WO1994003805A1 (en) 1992-08-07 1993-08-06 Down syndrome screening method utilizing dried blood samples

Publications (2)

Publication Number Publication Date
DE69332610D1 true DE69332610D1 (de) 2003-02-06
DE69332610T2 DE69332610T2 (de) 2003-10-16

Family

ID=25452087

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69332610T Expired - Lifetime DE69332610T2 (de) 1992-08-07 1993-08-06 Screeningverfahren für das down-syndrom unter verwendung von getrockneten blutproben

Country Status (10)

Country Link
US (1) US5252489A (de)
EP (1) EP0667958B1 (de)
JP (1) JP3529777B2 (de)
KR (1) KR100344085B1 (de)
AT (1) ATE230488T1 (de)
AU (1) AU688279B2 (de)
CA (1) CA2141870C (de)
DE (1) DE69332610T2 (de)
ES (1) ES2189799T3 (de)
WO (1) WO1994003805A1 (de)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5668117A (en) * 1991-02-22 1997-09-16 Shapiro; Howard K. Methods of treating neurological diseases and etiologically related symptomology using carbonyl trapping agents in combination with previously known medicaments
GB9224965D0 (en) * 1992-11-28 1993-01-20 Kodak Ltd Antenatal screening for chromosomal abnormalities
US5594637A (en) * 1993-05-26 1997-01-14 Base Ten Systems, Inc. System and method for assessing medical risk
US5583612A (en) * 1994-07-14 1996-12-10 Xerox Corporation Flexible latch with relaxed engagement
US5427953A (en) * 1993-11-08 1995-06-27 The Detroit Medical Center Blood testing method
US5432097A (en) * 1993-11-09 1995-07-11 Yourno; Joseph Method for recovery of blood cells from dried blood spots on filter paper
US5674727A (en) * 1994-08-31 1997-10-07 Cole; Laurence A. Human chorionic gonadotropin beta-subunit nicking enzyme
US5606164A (en) * 1996-01-16 1997-02-25 Boehringer Mannheim Corporation Method and apparatus for biological fluid analyte concentration measurement using generalized distance outlier detection
GB9606261D0 (en) * 1996-03-25 1996-05-29 Johnson & Johnson Clin Diag Prenatal screening for fetal abnormalities
ES2317656T3 (es) * 1996-09-06 2009-04-16 Yale University Cribado prenatal del sindrome de down utilizando gonadotropina hiperglicosilada.
US6066464A (en) * 1996-12-10 2000-05-23 Diagnostic Systems Laboratories, Inc. Immunoassay of IGF family of peptides, their binding proteins and related molecules in dried whole blood filter paper spots
US6177283B1 (en) * 1997-05-28 2001-01-23 Flexsite Diagnostics, Inc. Diagnostic assay
US6265223B1 (en) 1997-05-28 2001-07-24 Flexsite Diagnostics, Inc. Diagnostic assay
US5888740A (en) * 1997-09-19 1999-03-30 Genaco Biomedical Products, Inc. Detection of aneuploidy and gene deletion by PCR-based gene- dose co-amplification of chromosome specific sequences with synthetic sequences with synthetic internal controls
US6677123B1 (en) * 1998-02-03 2004-01-13 Wako Pure Chemical Industries, Ltd. Process for detecting increased risk of fetal chromosomal abnormality
JP2002533722A (ja) * 1998-12-29 2002-10-08 フレックスサイト ダイアノスティックス,インク. 遠隔地での生体サンプル採取装置および採取方法
US7238531B2 (en) 1999-01-30 2007-07-03 Pediatrix Screening, Inc. Method for interpreting tandem mass spectrometry data for clinical diagnosis
US7011977B2 (en) * 1999-01-30 2006-03-14 Sigma-Tau Pharmaceuticals, Inc. Quantification of carnitine levels in dialysis patients
US7297545B2 (en) * 1999-01-30 2007-11-20 Pediatrix Screening, Inc. Clinical method for the genetic screening of newborns using tandem mass spectrometry and internal standards therefor
BR0111473A (pt) * 2000-06-07 2004-01-13 Univ Duke Métodos para triar um indivìduo quanto a uma doença de armazenagem de glicogênio, para triar um indivìduo quanto à doença de pompe, para monitorar a condição clìnica de um indivìduo com doença de pompe, para estimar a eficácia de um regime terapêutico em um indivìduo com doença de pompe e para determinar a concentração de um oligossacarìdeo em uma amostra biológica
US7244233B2 (en) * 2003-07-29 2007-07-17 Ntd Laboratories, Inc. System and method for utilizing shape analysis to assess fetal abnormality
EP1663007A4 (de) * 2003-07-29 2009-05-13 Ntd Lab Inc System und verfahren zur beurteilung von fötalen abnormalitäten auf basis von bestimmten merkmalen
US7315787B2 (en) * 2003-10-07 2008-01-01 Ntd Laboratories, Inc. Multi-marker screening protocol for fetal abnormalities
CA2602963A1 (en) * 2005-03-24 2006-09-28 Beth Israel Deaconess Medical Center Methods of diagnosing fetal trisomy 13 or a risk of fetal trisomy 13 during pregnancy
WO2007121276A2 (en) * 2006-04-12 2007-10-25 Biocept, Inc. Enrichment of circulating fetal dna
US20100240054A1 (en) * 2008-09-22 2010-09-23 Biocept, Inc. Identification and isolation of fetal cells and nucleic acid
US20100216250A1 (en) * 2009-02-20 2010-08-26 Lopez Mary Frances Methods for Predicting Trisomy 21 in a Fetus
GB2496122A (en) * 2011-10-31 2013-05-08 Ge Healthcare Bio Sciences Ab Biological sample preservation on paper
CN108473932B (zh) 2015-09-09 2022-07-15 集联健康有限公司 用于样品收集、稳定化和保存的系统、方法和装置
TW202425920A (zh) 2017-01-10 2024-07-01 美商集聯健康有限公司 筒匣組裝件
SG11202112776QA (en) * 2019-05-17 2021-12-30 Irepertoire Inc Immunorepertoire wellness assessment systems and methods
WO2022091418A1 (ja) * 2020-11-02 2022-05-05 株式会社ヘルスケアシステムズ 尿検体を保存するための試薬、キット及び方法

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4016250A (en) * 1974-03-22 1977-04-05 Cornell Research Foundation, Inc. Method for testing for pregnancy
US4123224A (en) * 1975-12-17 1978-10-31 American Home Products Corporation Diagnostic test device
JPS54126723A (en) * 1978-03-23 1979-10-02 Teikoku Hormone Mfg Co Ltd Preparation of specific hcg and specific anti-hcg-beta-subunit antibody
US4565687A (en) * 1981-11-16 1986-01-21 The Reagents Of The University Of Michigan Monoclonal antibodies specific for the unbound β subunit of human chorionic gonadotropin
GR850899B (de) * 1984-04-12 1985-11-25 Gen Hospital Corp
US4874693A (en) * 1986-10-10 1989-10-17 Mark Bogart Method for assessing placental dysfunction
EP0362294B1 (de) * 1987-07-09 1993-06-30 3i RESEARCH EXPLOITATION LIMITED Pränatales screening für downs-syndrom
US5037305A (en) * 1988-11-16 1991-08-06 Vivigen, Inc. Graphic method for reporting risk to a patient
EP0666477B1 (de) * 1989-01-17 2003-10-15 JN Macri Technologies LLC, Inc. Einrichtung zum Nachweis vom Down syndrom durch nichtinvasive Siebtestung des mütterlichen Blutes
US5324667A (en) * 1989-01-17 1994-06-28 Macri James N Method for detecting down sydrown by non-invasive maternal blood screening
US5103836A (en) * 1990-02-28 1992-04-14 Epitope, Inc. Oral collection device and kit for immunoassay

Also Published As

Publication number Publication date
EP0667958A4 (de) 1997-07-16
WO1994003805A1 (en) 1994-02-17
US5252489A (en) 1993-10-12
KR100344085B1 (ko) 2002-11-04
JP3529777B2 (ja) 2004-05-24
AU5003593A (en) 1994-03-03
EP0667958A1 (de) 1995-08-23
ATE230488T1 (de) 2003-01-15
CA2141870A1 (en) 1994-02-17
AU688279B2 (en) 1998-03-12
JPH08500181A (ja) 1996-01-09
DE69332610T2 (de) 2003-10-16
ES2189799T3 (es) 2003-07-16
CA2141870C (en) 2004-10-19
EP0667958B1 (de) 2003-01-02

Similar Documents

Publication Publication Date Title
ATE230488T1 (de) Screeningverfahren für das down-syndrom unter verwendung von getrockneten blutproben
DE69739072D1 (de) Pränatales down-syndrom-testverfahren unter benutzung von hyperglykosyliertem gonadotropin
DE69729186T2 (de) Einstufiger immunoasssay mit einem trockenen "alles-in-einem"-reagens
WO2003001964A3 (en) Measurement testing of blood specimens
ATE227024T1 (de) Verfahren und vorrichtung zur feststellung des down-syndroms durch nichtinvasive analyse von mütterlichem blut
DE69931910D1 (en) Pränatales screening für downs-syndrom
DE69132269D1 (de) Verfahren zur gewinnung fötaler zellen
ATE496288T1 (de) Gleichzeitige mehrfachanalyse klinischer proben
IL129382A0 (en) Use of anti-embryonic hemoglobin antibodies to identify fetal cells
BR9707214A (pt) Processo para analisar uma amostra de constituição desconhecida por meio de um aparelho analìtico.
CA2482686A1 (en) A marker for measuring liver cirrhosis
Krantz et al. Maternal weight and ethnic adjustment within a first‐trimester Down syndrome and trisomy 18 screening program
Qin et al. Dual-label time-resolved immunofluorometric assay for simultaneous determination of pregnancy-associated plasma protein A and free β-subunit of human chorionic gonadotrophin
Spencer et al. Is maternal serum total hCG a marker of trisomy 21 in the first trimester of pregnancy?
ATE226415T1 (de) Leberfunktionstest
DE69525400D1 (de) Vorgeburtliche Überprüfung von Schwangerschaftsabnormitäten
DK115489A (da) Foerfoedselscreening for down's syndrom
Fuhrmann et al. First‐trimester alpha‐fetoprotein screening for Down syndrome
SE8904100D0 (sv) New analysis method
IT1270978B (it) Metodo per valutare automaticamente tipi di configurazioni di frazioni relativi ad una malattia
IT1231773B (it) Metodo e dispositivo fotometrico per analisi di campioni trattati con reattivi fluorescenti.
Conard et al. Automated amidolytic method for AT III determination
Evans et al. Standardization of methods reduces variability: explanation for historical discrepancies in biochemical screening
Talbot et al. Detection of maternal serum hCG glycoform variants in the second trimester of pregnancies affected by Down syndrome using a lectin immunoassay
Spencer et al. Evaluation of effect of analytical imprecision in maternal serum screening for Down's syndrome/Author's reply