DE69332610D1 - Screeningverfahren für das down-syndrom unter verwendung von getrockneten blutproben - Google Patents
Screeningverfahren für das down-syndrom unter verwendung von getrockneten blutprobenInfo
- Publication number
- DE69332610D1 DE69332610D1 DE69332610T DE69332610T DE69332610D1 DE 69332610 D1 DE69332610 D1 DE 69332610D1 DE 69332610 T DE69332610 T DE 69332610T DE 69332610 T DE69332610 T DE 69332610T DE 69332610 D1 DE69332610 D1 DE 69332610D1
- Authority
- DE
- Germany
- Prior art keywords
- dried blood
- trisomy
- hcg
- blood samples
- down syndrome
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/74—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
- G01N33/76—Human chorionic gonadotropin including luteinising hormone, follicle stimulating hormone, thyroid stimulating hormone or their receptors
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/815—Test for named compound or class of compounds
- Y10S436/817—Steroids or hormones
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/815—Test for named compound or class of compounds
- Y10S436/817—Steroids or hormones
- Y10S436/818—Human chorionic gonadotropin
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Endocrinology (AREA)
- Hematology (AREA)
- Physics & Mathematics (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Reproductive Health (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Cell Biology (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US07/925,683 US5252489A (en) | 1989-01-17 | 1992-08-07 | Down syndrome screening method utilizing dried blood samples |
PCT/US1993/007507 WO1994003805A1 (en) | 1992-08-07 | 1993-08-06 | Down syndrome screening method utilizing dried blood samples |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69332610D1 true DE69332610D1 (de) | 2003-02-06 |
DE69332610T2 DE69332610T2 (de) | 2003-10-16 |
Family
ID=25452087
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69332610T Expired - Lifetime DE69332610T2 (de) | 1992-08-07 | 1993-08-06 | Screeningverfahren für das down-syndrom unter verwendung von getrockneten blutproben |
Country Status (10)
Country | Link |
---|---|
US (1) | US5252489A (de) |
EP (1) | EP0667958B1 (de) |
JP (1) | JP3529777B2 (de) |
KR (1) | KR100344085B1 (de) |
AT (1) | ATE230488T1 (de) |
AU (1) | AU688279B2 (de) |
CA (1) | CA2141870C (de) |
DE (1) | DE69332610T2 (de) |
ES (1) | ES2189799T3 (de) |
WO (1) | WO1994003805A1 (de) |
Families Citing this family (32)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5668117A (en) * | 1991-02-22 | 1997-09-16 | Shapiro; Howard K. | Methods of treating neurological diseases and etiologically related symptomology using carbonyl trapping agents in combination with previously known medicaments |
GB9224965D0 (en) * | 1992-11-28 | 1993-01-20 | Kodak Ltd | Antenatal screening for chromosomal abnormalities |
US5594637A (en) * | 1993-05-26 | 1997-01-14 | Base Ten Systems, Inc. | System and method for assessing medical risk |
US5583612A (en) * | 1994-07-14 | 1996-12-10 | Xerox Corporation | Flexible latch with relaxed engagement |
US5427953A (en) * | 1993-11-08 | 1995-06-27 | The Detroit Medical Center | Blood testing method |
US5432097A (en) * | 1993-11-09 | 1995-07-11 | Yourno; Joseph | Method for recovery of blood cells from dried blood spots on filter paper |
US5674727A (en) * | 1994-08-31 | 1997-10-07 | Cole; Laurence A. | Human chorionic gonadotropin beta-subunit nicking enzyme |
US5606164A (en) * | 1996-01-16 | 1997-02-25 | Boehringer Mannheim Corporation | Method and apparatus for biological fluid analyte concentration measurement using generalized distance outlier detection |
GB9606261D0 (en) * | 1996-03-25 | 1996-05-29 | Johnson & Johnson Clin Diag | Prenatal screening for fetal abnormalities |
ES2317656T3 (es) * | 1996-09-06 | 2009-04-16 | Yale University | Cribado prenatal del sindrome de down utilizando gonadotropina hiperglicosilada. |
US6066464A (en) * | 1996-12-10 | 2000-05-23 | Diagnostic Systems Laboratories, Inc. | Immunoassay of IGF family of peptides, their binding proteins and related molecules in dried whole blood filter paper spots |
US6177283B1 (en) * | 1997-05-28 | 2001-01-23 | Flexsite Diagnostics, Inc. | Diagnostic assay |
US6265223B1 (en) | 1997-05-28 | 2001-07-24 | Flexsite Diagnostics, Inc. | Diagnostic assay |
US5888740A (en) * | 1997-09-19 | 1999-03-30 | Genaco Biomedical Products, Inc. | Detection of aneuploidy and gene deletion by PCR-based gene- dose co-amplification of chromosome specific sequences with synthetic sequences with synthetic internal controls |
US6677123B1 (en) * | 1998-02-03 | 2004-01-13 | Wako Pure Chemical Industries, Ltd. | Process for detecting increased risk of fetal chromosomal abnormality |
JP2002533722A (ja) * | 1998-12-29 | 2002-10-08 | フレックスサイト ダイアノスティックス,インク. | 遠隔地での生体サンプル採取装置および採取方法 |
US7238531B2 (en) | 1999-01-30 | 2007-07-03 | Pediatrix Screening, Inc. | Method for interpreting tandem mass spectrometry data for clinical diagnosis |
US7011977B2 (en) * | 1999-01-30 | 2006-03-14 | Sigma-Tau Pharmaceuticals, Inc. | Quantification of carnitine levels in dialysis patients |
US7297545B2 (en) * | 1999-01-30 | 2007-11-20 | Pediatrix Screening, Inc. | Clinical method for the genetic screening of newborns using tandem mass spectrometry and internal standards therefor |
BR0111473A (pt) * | 2000-06-07 | 2004-01-13 | Univ Duke | Métodos para triar um indivìduo quanto a uma doença de armazenagem de glicogênio, para triar um indivìduo quanto à doença de pompe, para monitorar a condição clìnica de um indivìduo com doença de pompe, para estimar a eficácia de um regime terapêutico em um indivìduo com doença de pompe e para determinar a concentração de um oligossacarìdeo em uma amostra biológica |
US7244233B2 (en) * | 2003-07-29 | 2007-07-17 | Ntd Laboratories, Inc. | System and method for utilizing shape analysis to assess fetal abnormality |
EP1663007A4 (de) * | 2003-07-29 | 2009-05-13 | Ntd Lab Inc | System und verfahren zur beurteilung von fötalen abnormalitäten auf basis von bestimmten merkmalen |
US7315787B2 (en) * | 2003-10-07 | 2008-01-01 | Ntd Laboratories, Inc. | Multi-marker screening protocol for fetal abnormalities |
CA2602963A1 (en) * | 2005-03-24 | 2006-09-28 | Beth Israel Deaconess Medical Center | Methods of diagnosing fetal trisomy 13 or a risk of fetal trisomy 13 during pregnancy |
WO2007121276A2 (en) * | 2006-04-12 | 2007-10-25 | Biocept, Inc. | Enrichment of circulating fetal dna |
US20100240054A1 (en) * | 2008-09-22 | 2010-09-23 | Biocept, Inc. | Identification and isolation of fetal cells and nucleic acid |
US20100216250A1 (en) * | 2009-02-20 | 2010-08-26 | Lopez Mary Frances | Methods for Predicting Trisomy 21 in a Fetus |
GB2496122A (en) * | 2011-10-31 | 2013-05-08 | Ge Healthcare Bio Sciences Ab | Biological sample preservation on paper |
CN108473932B (zh) | 2015-09-09 | 2022-07-15 | 集联健康有限公司 | 用于样品收集、稳定化和保存的系统、方法和装置 |
TW202425920A (zh) | 2017-01-10 | 2024-07-01 | 美商集聯健康有限公司 | 筒匣組裝件 |
SG11202112776QA (en) * | 2019-05-17 | 2021-12-30 | Irepertoire Inc | Immunorepertoire wellness assessment systems and methods |
WO2022091418A1 (ja) * | 2020-11-02 | 2022-05-05 | 株式会社ヘルスケアシステムズ | 尿検体を保存するための試薬、キット及び方法 |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4016250A (en) * | 1974-03-22 | 1977-04-05 | Cornell Research Foundation, Inc. | Method for testing for pregnancy |
US4123224A (en) * | 1975-12-17 | 1978-10-31 | American Home Products Corporation | Diagnostic test device |
JPS54126723A (en) * | 1978-03-23 | 1979-10-02 | Teikoku Hormone Mfg Co Ltd | Preparation of specific hcg and specific anti-hcg-beta-subunit antibody |
US4565687A (en) * | 1981-11-16 | 1986-01-21 | The Reagents Of The University Of Michigan | Monoclonal antibodies specific for the unbound β subunit of human chorionic gonadotropin |
GR850899B (de) * | 1984-04-12 | 1985-11-25 | Gen Hospital Corp | |
US4874693A (en) * | 1986-10-10 | 1989-10-17 | Mark Bogart | Method for assessing placental dysfunction |
EP0362294B1 (de) * | 1987-07-09 | 1993-06-30 | 3i RESEARCH EXPLOITATION LIMITED | Pränatales screening für downs-syndrom |
US5037305A (en) * | 1988-11-16 | 1991-08-06 | Vivigen, Inc. | Graphic method for reporting risk to a patient |
EP0666477B1 (de) * | 1989-01-17 | 2003-10-15 | JN Macri Technologies LLC, Inc. | Einrichtung zum Nachweis vom Down syndrom durch nichtinvasive Siebtestung des mütterlichen Blutes |
US5324667A (en) * | 1989-01-17 | 1994-06-28 | Macri James N | Method for detecting down sydrown by non-invasive maternal blood screening |
US5103836A (en) * | 1990-02-28 | 1992-04-14 | Epitope, Inc. | Oral collection device and kit for immunoassay |
-
1992
- 1992-08-07 US US07/925,683 patent/US5252489A/en not_active Expired - Lifetime
-
1993
- 1993-08-06 WO PCT/US1993/007507 patent/WO1994003805A1/en active IP Right Grant
- 1993-08-06 JP JP50562094A patent/JP3529777B2/ja not_active Expired - Lifetime
- 1993-08-06 AU AU50035/93A patent/AU688279B2/en not_active Expired
- 1993-08-06 DE DE69332610T patent/DE69332610T2/de not_active Expired - Lifetime
- 1993-08-06 CA CA002141870A patent/CA2141870C/en not_active Expired - Lifetime
- 1993-08-06 ES ES94906738T patent/ES2189799T3/es not_active Expired - Lifetime
- 1993-08-06 EP EP94906738A patent/EP0667958B1/de not_active Expired - Lifetime
- 1993-08-06 AT AT94906738T patent/ATE230488T1/de not_active IP Right Cessation
- 1993-08-06 KR KR1019950700506A patent/KR100344085B1/ko not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
EP0667958A4 (de) | 1997-07-16 |
WO1994003805A1 (en) | 1994-02-17 |
US5252489A (en) | 1993-10-12 |
KR100344085B1 (ko) | 2002-11-04 |
JP3529777B2 (ja) | 2004-05-24 |
AU5003593A (en) | 1994-03-03 |
EP0667958A1 (de) | 1995-08-23 |
ATE230488T1 (de) | 2003-01-15 |
CA2141870A1 (en) | 1994-02-17 |
AU688279B2 (en) | 1998-03-12 |
JPH08500181A (ja) | 1996-01-09 |
DE69332610T2 (de) | 2003-10-16 |
ES2189799T3 (es) | 2003-07-16 |
CA2141870C (en) | 2004-10-19 |
EP0667958B1 (de) | 2003-01-02 |
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