ES2189799T3 - Metodo para detectar sindrome de down utilizando muestras de sangre seca. - Google Patents
Metodo para detectar sindrome de down utilizando muestras de sangre seca.Info
- Publication number
- ES2189799T3 ES2189799T3 ES94906738T ES94906738T ES2189799T3 ES 2189799 T3 ES2189799 T3 ES 2189799T3 ES 94906738 T ES94906738 T ES 94906738T ES 94906738 T ES94906738 T ES 94906738T ES 2189799 T3 ES2189799 T3 ES 2189799T3
- Authority
- ES
- Spain
- Prior art keywords
- trisomy
- hcg
- blood samples
- down syndrome
- free beta
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/74—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
- G01N33/76—Human chorionic gonadotropin including luteinising hormone, follicle stimulating hormone, thyroid stimulating hormone or their receptors
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/815—Test for named compound or class of compounds
- Y10S436/817—Steroids or hormones
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/815—Test for named compound or class of compounds
- Y10S436/817—Steroids or hormones
- Y10S436/818—Human chorionic gonadotropin
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Endocrinology (AREA)
- Hematology (AREA)
- Physics & Mathematics (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Reproductive Health (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Cell Biology (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Abstract
LA PRESENTE INVENCION SE REFIERE A UN METODO PARA DETECTAR EL SINDROME DE DOWN (TRISOMY 21), TRISOMY 13, TRISOMY 18 Y OTRAS ANOMALIAS DE LOS CROMOSOMAS DURANTE LA INVESTIGACION PRENATAL, POR ANALISIS DE UNA MUESTRA DE SANGRE SECA DE UNA MUJER EMBARAZADA. EN PARTICULAR, LA PRESENTE INVENCION SE REFIERE A UN METODO PARA MEJORAR LA EFICACIA DE DETECCION EN LA INVESTIGACION CONTRA ANOMALIAS MEDIANTE MEDICION DE LA CANTIDAD DE GONADOTROPIN CORIONICO HUMANO BETA LIBRE (HCG) Y FORMAS MARCADAS O FRAGMENTADAS O ABERRANTES DE (HCG) BETA LIBRE, TODO LO CUAL ESTA REFERENCIADO MEDIANTE ESTA APLICACION COMO (HCG) BETA LIBRE EN MUESTRAS DE SANGRE SECA DE UNA MUJER EMBARAZADA.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US07/925,683 US5252489A (en) | 1989-01-17 | 1992-08-07 | Down syndrome screening method utilizing dried blood samples |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2189799T3 true ES2189799T3 (es) | 2003-07-16 |
Family
ID=25452087
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES94906738T Expired - Lifetime ES2189799T3 (es) | 1992-08-07 | 1993-08-06 | Metodo para detectar sindrome de down utilizando muestras de sangre seca. |
Country Status (10)
Country | Link |
---|---|
US (1) | US5252489A (es) |
EP (1) | EP0667958B1 (es) |
JP (1) | JP3529777B2 (es) |
KR (1) | KR100344085B1 (es) |
AT (1) | ATE230488T1 (es) |
AU (1) | AU688279B2 (es) |
CA (1) | CA2141870C (es) |
DE (1) | DE69332610T2 (es) |
ES (1) | ES2189799T3 (es) |
WO (1) | WO1994003805A1 (es) |
Families Citing this family (32)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5668117A (en) * | 1991-02-22 | 1997-09-16 | Shapiro; Howard K. | Methods of treating neurological diseases and etiologically related symptomology using carbonyl trapping agents in combination with previously known medicaments |
GB9224965D0 (en) * | 1992-11-28 | 1993-01-20 | Kodak Ltd | Antenatal screening for chromosomal abnormalities |
US5594637A (en) * | 1993-05-26 | 1997-01-14 | Base Ten Systems, Inc. | System and method for assessing medical risk |
US5583612A (en) * | 1994-07-14 | 1996-12-10 | Xerox Corporation | Flexible latch with relaxed engagement |
US5427953A (en) * | 1993-11-08 | 1995-06-27 | The Detroit Medical Center | Blood testing method |
US5432097A (en) * | 1993-11-09 | 1995-07-11 | Yourno; Joseph | Method for recovery of blood cells from dried blood spots on filter paper |
US5674727A (en) * | 1994-08-31 | 1997-10-07 | Cole; Laurence A. | Human chorionic gonadotropin beta-subunit nicking enzyme |
US5606164A (en) * | 1996-01-16 | 1997-02-25 | Boehringer Mannheim Corporation | Method and apparatus for biological fluid analyte concentration measurement using generalized distance outlier detection |
GB9606261D0 (en) * | 1996-03-25 | 1996-05-29 | Johnson & Johnson Clin Diag | Prenatal screening for fetal abnormalities |
DK0923730T3 (da) * | 1996-09-06 | 2009-02-09 | Univ Yale | Prænatal screening for Down's syndrom ved anvendelse af hyperglykosyleret gonadotropin |
US6066464A (en) * | 1996-12-10 | 2000-05-23 | Diagnostic Systems Laboratories, Inc. | Immunoassay of IGF family of peptides, their binding proteins and related molecules in dried whole blood filter paper spots |
US6177283B1 (en) * | 1997-05-28 | 2001-01-23 | Flexsite Diagnostics, Inc. | Diagnostic assay |
US6265223B1 (en) | 1997-05-28 | 2001-07-24 | Flexsite Diagnostics, Inc. | Diagnostic assay |
US5888740A (en) * | 1997-09-19 | 1999-03-30 | Genaco Biomedical Products, Inc. | Detection of aneuploidy and gene deletion by PCR-based gene- dose co-amplification of chromosome specific sequences with synthetic sequences with synthetic internal controls |
US6677123B1 (en) * | 1998-02-03 | 2004-01-13 | Wako Pure Chemical Industries, Ltd. | Process for detecting increased risk of fetal chromosomal abnormality |
CA2353066A1 (en) * | 1998-12-29 | 2000-07-06 | Flexsite Diagnostics, Inc. | Remote site urine collection device and method of use |
US7011977B2 (en) * | 1999-01-30 | 2006-03-14 | Sigma-Tau Pharmaceuticals, Inc. | Quantification of carnitine levels in dialysis patients |
US7297545B2 (en) * | 1999-01-30 | 2007-11-20 | Pediatrix Screening, Inc. | Clinical method for the genetic screening of newborns using tandem mass spectrometry and internal standards therefor |
US7238531B2 (en) * | 1999-01-30 | 2007-07-03 | Pediatrix Screening, Inc. | Method for interpreting tandem mass spectrometry data for clinical diagnosis |
AU2001266733A1 (en) * | 2000-06-07 | 2001-12-17 | Duke University | Diagnostic methods for pompe disease and other glycogen storage diseases |
US7244233B2 (en) * | 2003-07-29 | 2007-07-17 | Ntd Laboratories, Inc. | System and method for utilizing shape analysis to assess fetal abnormality |
CA2576646C (en) * | 2003-07-29 | 2011-02-08 | Ntd Laboratories, Inc. | System and method for assessing fetal abnormality based on landmarks |
US7315787B2 (en) * | 2003-10-07 | 2008-01-01 | Ntd Laboratories, Inc. | Multi-marker screening protocol for fetal abnormalities |
CA2602963A1 (en) * | 2005-03-24 | 2006-09-28 | Beth Israel Deaconess Medical Center | Methods of diagnosing fetal trisomy 13 or a risk of fetal trisomy 13 during pregnancy |
WO2007121276A2 (en) * | 2006-04-12 | 2007-10-25 | Biocept, Inc. | Enrichment of circulating fetal dna |
US20100240054A1 (en) * | 2008-09-22 | 2010-09-23 | Biocept, Inc. | Identification and isolation of fetal cells and nucleic acid |
US20100216250A1 (en) * | 2009-02-20 | 2010-08-26 | Lopez Mary Frances | Methods for Predicting Trisomy 21 in a Fetus |
GB2496122A (en) * | 2011-10-31 | 2013-05-08 | Ge Healthcare Bio Sciences Ab | Biological sample preservation on paper |
EP4289356A3 (en) | 2015-09-09 | 2024-02-28 | Drawbridge Health, Inc. | Devices for sample collection, stabilization and preservation |
GB2576635B (en) | 2017-01-10 | 2020-08-05 | Drawbridge Health Inc | Devices, systems, and methods for sample collection |
SG11202112776QA (en) * | 2019-05-17 | 2021-12-30 | Irepertoire Inc | Immunorepertoire wellness assessment systems and methods |
WO2022091418A1 (ja) * | 2020-11-02 | 2022-05-05 | 株式会社ヘルスケアシステムズ | 尿検体を保存するための試薬、キット及び方法 |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4016250A (en) * | 1974-03-22 | 1977-04-05 | Cornell Research Foundation, Inc. | Method for testing for pregnancy |
US4123224A (en) * | 1975-12-17 | 1978-10-31 | American Home Products Corporation | Diagnostic test device |
JPS54126723A (en) * | 1978-03-23 | 1979-10-02 | Teikoku Hormone Mfg Co Ltd | Preparation of specific hcg and specific anti-hcg-beta-subunit antibody |
US4565687A (en) * | 1981-11-16 | 1986-01-21 | The Reagents Of The University Of Michigan | Monoclonal antibodies specific for the unbound β subunit of human chorionic gonadotropin |
GR850899B (es) * | 1984-04-12 | 1985-11-25 | Gen Hospital Corp | |
US4874693A (en) * | 1986-10-10 | 1989-10-17 | Mark Bogart | Method for assessing placental dysfunction |
ATE91182T1 (de) * | 1987-07-09 | 1993-07-15 | 3I Res Expl Ltd | Praenatales screening fuer downs-syndrom. |
US5037305A (en) * | 1988-11-16 | 1991-08-06 | Vivigen, Inc. | Graphic method for reporting risk to a patient |
US5324667A (en) * | 1989-01-17 | 1994-06-28 | Macri James N | Method for detecting down sydrown by non-invasive maternal blood screening |
DK0666477T3 (da) * | 1989-01-17 | 2004-02-23 | Jn Macri Technologies Llc | Apparat til detektering af Downs syndrom ved hjælp af non-invasiv maternel blodscreening |
US5103836A (en) * | 1990-02-28 | 1992-04-14 | Epitope, Inc. | Oral collection device and kit for immunoassay |
-
1992
- 1992-08-07 US US07/925,683 patent/US5252489A/en not_active Expired - Lifetime
-
1993
- 1993-08-06 CA CA002141870A patent/CA2141870C/en not_active Expired - Lifetime
- 1993-08-06 KR KR1019950700506A patent/KR100344085B1/ko not_active IP Right Cessation
- 1993-08-06 AU AU50035/93A patent/AU688279B2/en not_active Expired
- 1993-08-06 WO PCT/US1993/007507 patent/WO1994003805A1/en active IP Right Grant
- 1993-08-06 ES ES94906738T patent/ES2189799T3/es not_active Expired - Lifetime
- 1993-08-06 AT AT94906738T patent/ATE230488T1/de not_active IP Right Cessation
- 1993-08-06 DE DE69332610T patent/DE69332610T2/de not_active Expired - Lifetime
- 1993-08-06 JP JP50562094A patent/JP3529777B2/ja not_active Expired - Lifetime
- 1993-08-06 EP EP94906738A patent/EP0667958B1/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
JPH08500181A (ja) | 1996-01-09 |
EP0667958A1 (en) | 1995-08-23 |
AU5003593A (en) | 1994-03-03 |
DE69332610T2 (de) | 2003-10-16 |
DE69332610D1 (de) | 2003-02-06 |
US5252489A (en) | 1993-10-12 |
WO1994003805A1 (en) | 1994-02-17 |
AU688279B2 (en) | 1998-03-12 |
EP0667958B1 (en) | 2003-01-02 |
EP0667958A4 (en) | 1997-07-16 |
KR100344085B1 (ko) | 2002-11-04 |
CA2141870A1 (en) | 1994-02-17 |
CA2141870C (en) | 2004-10-19 |
JP3529777B2 (ja) | 2004-05-24 |
ATE230488T1 (de) | 2003-01-15 |
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