DE69330252T2 - Zusammensetzungen für die regulation der cytokinaktivität - Google Patents

Zusammensetzungen für die regulation der cytokinaktivität

Info

Publication number
DE69330252T2
DE69330252T2 DE69330252T DE69330252T DE69330252T2 DE 69330252 T2 DE69330252 T2 DE 69330252T2 DE 69330252 T DE69330252 T DE 69330252T DE 69330252 T DE69330252 T DE 69330252T DE 69330252 T2 DE69330252 T2 DE 69330252T2
Authority
DE
Germany
Prior art keywords
host
compositions
sulfated
acetylated
substances
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69330252T
Other languages
English (en)
Other versions
DE69330252D1 (de
Inventor
Irun R Cohen
Ofer Lider
Liora Cahalon
Oded Shoseyov
Raanan Margalit
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Yeda Research and Development Co Ltd
Original Assignee
Yeda Research and Development Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Yeda Research and Development Co Ltd filed Critical Yeda Research and Development Co Ltd
Publication of DE69330252D1 publication Critical patent/DE69330252D1/de
Application granted granted Critical
Publication of DE69330252T2 publication Critical patent/DE69330252T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7024—Esters of saccharides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7016—Disaccharides, e.g. lactose, lactulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H11/00—Compounds containing saccharide radicals esterified by inorganic acids; Metal salts thereof

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Genetics & Genomics (AREA)
  • Immunology (AREA)
  • Oncology (AREA)
  • Rheumatology (AREA)
  • Communicable Diseases (AREA)
  • Virology (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Cosmetics (AREA)
  • Saccharide Compounds (AREA)
  • Orthopedics, Nursing, And Contraception (AREA)
DE69330252T 1992-11-10 1993-11-09 Zusammensetzungen für die regulation der cytokinaktivität Expired - Fee Related DE69330252T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US97475092A 1992-11-10 1992-11-10
US9673993A 1993-07-23 1993-07-23
PCT/US1993/010868 WO1994011006A1 (en) 1992-11-10 1993-11-09 Compositions for the regulation of cytokine activity

Publications (2)

Publication Number Publication Date
DE69330252D1 DE69330252D1 (de) 2001-06-28
DE69330252T2 true DE69330252T2 (de) 2002-02-07

Family

ID=26792027

Family Applications (2)

Application Number Title Priority Date Filing Date
DE69330252T Expired - Fee Related DE69330252T2 (de) 1992-11-10 1993-11-09 Zusammensetzungen für die regulation der cytokinaktivität
DE69334102T Expired - Fee Related DE69334102T2 (de) 1992-11-10 1993-11-09 Zusammenstellung zur Regulierung der Zytokinaktivität

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE69334102T Expired - Fee Related DE69334102T2 (de) 1992-11-10 1993-11-09 Zusammenstellung zur Regulierung der Zytokinaktivität

Country Status (18)

Country Link
EP (2) EP1095657B1 (de)
JP (1) JPH08506322A (de)
CN (1) CN1093904A (de)
AT (1) ATE201327T1 (de)
AU (2) AU686581B2 (de)
CA (1) CA2149116A1 (de)
DE (2) DE69330252T2 (de)
FI (1) FI952267A (de)
HR (1) HRP931389A2 (de)
HU (1) HUT70945A (de)
IL (1) IL107563A (de)
NO (1) NO951822L (de)
NZ (1) NZ258367A (de)
PL (1) PL309001A1 (de)
SI (1) SI9300586A (de)
TW (1) TW257678B (de)
WO (1) WO1994011006A1 (de)
YU (1) YU71393A (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6750207B1 (en) 1992-05-01 2004-06-15 Yeda Research And Development Co. Ltd. Compositions for the regulation of cytokine activity
WO1994011006A1 (en) * 1992-11-10 1994-05-26 Yeda Research And Development Co. Ltd. Compositions for the regulation of cytokine activity
AU2002243630A1 (en) 2001-01-23 2002-08-06 Massachusetts Institute Of Technology Solid- and solution -phase synthesis of heparin and other glycosaminoglycans
US7285536B2 (en) 2001-12-05 2007-10-23 Yeda Research And Development Co., Ltd. Anti-cancer therapeutic compounds
ITMI20021294A1 (it) * 2002-06-12 2003-12-12 Inalco Spa Polisaccaridi batterici o-solfatati e loro uso
US20060293275A1 (en) * 2004-03-29 2006-12-28 Toshikazu Nakamura Hgf production accelerator containing heparin-like oligosaccharide
ITMI20091445A1 (it) * 2009-08-07 2011-02-08 Inalco S P A A Socio Unico Derivati semi-sintetici del polisaccaride k5 per la prevenzione ed il trattamento del danno tissutale associato a ischemia e/o riperfusione
US8992653B2 (en) 2011-09-08 2015-03-31 Novozymes Bioag A/S Seed treatment methods and compositions
MX351416B (es) * 2011-09-23 2017-10-13 Novozymes Bioag As Quitooligosacaridos y metodos para el uso en el mejoramiento de crecimiento de plantas.
CN102824352B (zh) * 2011-10-11 2013-09-04 泸州医学院 一种双糖化合物在制备抗肿瘤药物中的用途
CN109730006B (zh) * 2019-03-19 2022-10-18 西华大学 提高动物黑色素含量的方法
CN110646557A (zh) * 2019-10-12 2020-01-03 北京航空航天大学 携带idh基因突变的胶质母细胞瘤患者的尿液代谢标志物及其用途
EP4117683A4 (de) 2020-03-12 2024-04-24 Cullis Hill Sydney David Behandlung von coronavirus-infektion und damit verbundener zytokin-toxizität

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL61201A (en) * 1979-10-05 1984-09-30 Choay Sa Oligosaccharides having no more than 8 saccharide moieties,their obtention from heparin and pharmaceutical compositions containing them
US4818816A (en) * 1981-04-28 1989-04-04 Choay, S.A. Process for the organic synthesis of oligosaccharides and derivatives thereof
AU563351C (en) * 1982-01-15 2003-06-19 Glaxo Group Limited Synthesis of oligosaccharides
FR2538404B1 (de) * 1982-12-28 1985-08-23 Anic Spa
IT1195497B (it) * 1983-03-08 1988-10-19 Opocrin Spa Procedimento per la preparazione di frazioni oligosaccaridiche dotate di proprieta' farmacologiche per degradazione chimica di eparina
FR2597484B1 (fr) * 1986-04-17 1988-12-23 Sanofi Sa Glycosaminoglycanes de type heparine ou heparane-sulfate dotes d'une activite sur la division et la differentiation cellulaires, leur preparation et leurs applications therapeutiques.
FR2614026B1 (fr) * 1987-04-16 1992-04-17 Sanofi Sa Heparines de bas poids moleculaire, a structure reguliere, leur preparation et leurs applications biologiques
JPH0818993B2 (ja) * 1989-11-28 1996-02-28 キッセイ薬品工業株式会社 プロスタグランジンｉ▲下２▼産生増強剤
BE1004029A6 (nl) * 1990-11-22 1992-09-08 Mol Omer De Farmaceutische samenstelling en farmaceutische set voor het behandelen van kanker.
DE69232615T2 (de) * 1991-05-02 2003-01-30 Yeda Res & Dev Zusammensetzungen zur verhütung und/oder behandlung von pathologischen prozessen
WO1994011006A1 (en) * 1992-11-10 1994-05-26 Yeda Research And Development Co. Ltd. Compositions for the regulation of cytokine activity

Also Published As

Publication number Publication date
YU71393A (sh) 1997-05-28
EP1095657A2 (de) 2001-05-02
EP1095657A3 (de) 2004-02-25
DE69334102T2 (de) 2007-10-18
HU9501373D0 (en) 1995-06-28
AU686581B2 (en) 1998-02-12
NO951822L (no) 1995-06-29
SI9300586A (en) 1994-09-30
IL107563A (en) 2006-12-31
PL309001A1 (en) 1995-09-18
CA2149116A1 (en) 1994-05-26
HUT70945A (en) 1995-11-28
DE69330252D1 (de) 2001-06-28
EP0669827A1 (de) 1995-09-06
EP0669827A4 (de) 1996-08-28
DE69334102D1 (de) 2007-02-22
CN1093904A (zh) 1994-10-26
EP0669827B1 (de) 2001-05-23
HRP931389A2 (en) 1995-04-30
FI952267A (fi) 1995-07-10
ATE201327T1 (de) 2001-06-15
NZ258367A (en) 1997-02-24
NO951822D0 (no) 1995-05-09
AU5599394A (en) 1994-06-08
FI952267A0 (fi) 1995-05-10
AU6478398A (en) 1998-06-25
IL107563A0 (en) 1994-02-27
EP1095657B1 (de) 2007-01-10
JPH08506322A (ja) 1996-07-09
TW257678B (de) 1995-09-21
AU699624B2 (en) 1998-12-10
WO1994011006A1 (en) 1994-05-26

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee