DE69328618D1 - Medikamente auf der Basis von Docosahexaensäure, als Plättchenaggregationshemmer und gegen cerebralen Mangel an Fettsäuren, und Verfahren zur Herstellung. - Google Patents

Medikamente auf der Basis von Docosahexaensäure, als Plättchenaggregationshemmer und gegen cerebralen Mangel an Fettsäuren, und Verfahren zur Herstellung.

Info

Publication number
DE69328618D1
DE69328618D1 DE69328618T DE69328618T DE69328618D1 DE 69328618 D1 DE69328618 D1 DE 69328618D1 DE 69328618 T DE69328618 T DE 69328618T DE 69328618 T DE69328618 T DE 69328618T DE 69328618 D1 DE69328618 D1 DE 69328618D1
Authority
DE
Germany
Prior art keywords
pct
dha
manufacture
fatty acids
platelet aggregation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69328618T
Other languages
English (en)
Other versions
DE69328618T2 (de
Inventor
Yves Bayon
Martine Croset
Michel Lagarde
Jean Lecerf
Frank Thies
Jean-Louis Tayot
Veronique Chirouze
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
IMEDEX CHAPONOST
Institut National de la Sante et de la Recherche Medicale INSERM
Original Assignee
IMEDEX CHAPONOST
Institut National de la Sante et de la Recherche Medicale INSERM
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by IMEDEX CHAPONOST, Institut National de la Sante et de la Recherche Medicale INSERM filed Critical IMEDEX CHAPONOST
Publication of DE69328618D1 publication Critical patent/DE69328618D1/de
Application granted granted Critical
Publication of DE69328618T2 publication Critical patent/DE69328618T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A61K31/23—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Urology & Nephrology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Emergency Medicine (AREA)
  • Epidemiology (AREA)
  • Vascular Medicine (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
DE69328618T 1992-11-24 1993-11-24 Medikamente auf der Basis von Docosahexaensäure, als Plättchenaggregationshemmer und gegen cerebralen Mangel an Fettsäuren, und Verfahren zur Herstellung. Expired - Fee Related DE69328618T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9214078A FR2698269B1 (fr) 1992-11-24 1992-11-24 Nouveaux médicaments à base d'acides gras insaturés, utilisables notamment comme antiagrégants plaquettaires et/ou comme transporteurs privilégiés vers le cerveau.
PCT/FR1993/001158 WO1994012170A2 (fr) 1992-11-24 1993-11-24 Medicaments a base d'acides gras polyinsatures, notamment d'acides docosahexaenoique comme antiagregants plaquettaires et contre des carences cerebrales en acides gras essentiels.

Publications (2)

Publication Number Publication Date
DE69328618D1 true DE69328618D1 (de) 2000-06-15
DE69328618T2 DE69328618T2 (de) 2001-02-01

Family

ID=9435824

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69328618T Expired - Fee Related DE69328618T2 (de) 1992-11-24 1993-11-24 Medikamente auf der Basis von Docosahexaensäure, als Plättchenaggregationshemmer und gegen cerebralen Mangel an Fettsäuren, und Verfahren zur Herstellung.

Country Status (10)

Country Link
US (1) US5654290A (de)
EP (1) EP0623019B1 (de)
JP (1) JPH07503488A (de)
AT (1) ATE192647T1 (de)
CA (1) CA2128706C (de)
DE (1) DE69328618T2 (de)
DK (1) DK0623019T3 (de)
ES (1) ES2149253T3 (de)
FR (1) FR2698269B1 (de)
WO (1) WO1994012170A2 (de)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6107499A (en) * 1988-02-26 2000-08-22 Neuromedica, Inc. Dopamine analog amide
US6576636B2 (en) 1996-05-22 2003-06-10 Protarga, Inc. Method of treating a liver disorder with fatty acid-antiviral agent conjugates
US5795909A (en) 1996-05-22 1998-08-18 Neuromedica, Inc. DHA-pharmaceutical agent conjugates of taxanes
US6197764B1 (en) 1997-11-26 2001-03-06 Protarga, Inc. Clozapine compositions and uses thereof
US5955459A (en) * 1997-11-26 1999-09-21 Neuromedica, Inc. Fatty acid-antipsychotic compositions and uses thereof
US5977174A (en) * 1997-11-26 1999-11-02 Neuromedica, Inc. Cholinergic compositions and uses thereof
US6153653A (en) * 1997-11-26 2000-11-28 Protarga, Inc. Choline compositions and uses thereof
US6225444B1 (en) 1998-02-10 2001-05-01 Protarga, Inc. Neuroprotective peptides and uses thereof
US7235583B1 (en) * 1999-03-09 2007-06-26 Luitpold Pharmaceuticals, Inc., Fatty acid-anticancer conjugates and uses thereof
ATE556706T1 (de) 2001-03-23 2012-05-15 Luitpold Pharm Inc Fettalkohol-arzneimittel-konjugate
JP2005500988A (ja) 2001-03-23 2005-01-13 ルイトポルド・ファーマシューティカルズ・インコーポレーテッド 脂肪族アミン薬物複合体
IL142952A (en) * 2001-05-03 2005-12-18 Enzmotec Ltd Process for enzyme-catalyzed production of 1,2 diacylated phospholipids
WO2004091603A1 (fr) * 2003-04-07 2004-10-28 Clinigenetics Utilisation d’un ester de dha pour le traitement des malades cardiovasculaires
EP1466597A1 (de) * 2003-04-07 2004-10-13 Clinigenetics Verwendung von dha-Esteren in der Behandlung kardiovasculärer Krankheiten
FR2857265A1 (fr) * 2003-07-08 2005-01-14 Clinigenetics Utilisation de lyso-pcdha pour le traitement des maladies cardiovasculaires
CA2549429A1 (en) * 2003-12-22 2005-07-07 Wakunaga Pharmaceutical Co., Ltd. Fat composition
JP5352961B2 (ja) * 2006-03-28 2013-11-27 Ｊｎｃ株式会社 生活習慣病予防・治療剤
FR2979825B1 (fr) 2011-09-13 2013-11-29 Inst Nat Sciences Appliq Phosphatidylcholines specifiques en tant que modulateurs de l'activite du facteur d'activation plaquettaire
AU2014203179C1 (en) 2013-06-14 2017-05-04 Aker Biomarine Antarctic As Lipid extraction processes
US9216199B2 (en) 2013-12-05 2015-12-22 Buriva, LLC Nutritional supplement containing phospholipid-DHA derived from eggs
US9233114B2 (en) 2013-12-05 2016-01-12 Buriva, LLC Dietary supplement containing phospholipid-DHA derived from eggs
US9549937B2 (en) 2013-12-05 2017-01-24 Burvia, LLC. Composition containing phospholipid-DHA and folate
US9610302B2 (en) 2013-12-05 2017-04-04 Buriva, LLC. Composition containing phospholipid-DHA and B vitamins
WO2019123015A1 (en) 2017-12-21 2019-06-27 Aker Biomarine Antarctic As Lysophosphatidylcholine compositions

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2098065A (en) * 1981-04-14 1982-11-17 Nippon Suisan Kaisha Ltd Antithrombotic compositions containing docosahexaenoic acid
IT1223290B (it) * 1987-07-27 1990-09-19 Indena Spa Acidi poliinsaturi ad azione vasocinetica e relative formulazioni farmaceutiche e cosmetiche
JPS6450890A (en) * 1987-08-20 1989-02-27 Nippon Oils & Fats Co Ltd Production of docosahexaenoic acid-containing phosphatidyl choline
JP2537645B2 (ja) * 1987-11-13 1996-09-25 雪印乳業株式会社 薬剤的活性を有する栄養組成物
JPH01203330A (ja) * 1988-02-05 1989-08-16 Rikagaku Kenkyusho 制癌剤
JP2524217B2 (ja) * 1988-04-18 1996-08-14 マルハ株式会社 脳機能改善組成物、学習能力増強剤、記憶力増強剤、痴呆予防剤または痴呆治療剤
GB2218904A (en) * 1988-05-27 1989-11-29 Renafield Limited Pharmaceutical composition based on high-concentration esters of docosahexaenoic acid
IT1230141B (it) * 1989-05-03 1991-10-14 Fidia Spa Impiego di derivati della fosfatidil carnitina per la preparazione di composizioni farmaceutiche aventi attivita' nella terapia delle patologie dell'uomo associate con un danno neuronale.
JPH03178931A (ja) * 1989-09-08 1991-08-02 Nippon Oil & Fats Co Ltd 睡眠増加剤
JPH0748992B2 (ja) * 1990-04-16 1995-05-31 日本油脂株式会社 血栓防止用粉末組成物
JP3092180B2 (ja) * 1991-02-27 2000-09-25 日本油脂株式会社 低密度リポ蛋白受容体活性化剤

Also Published As

Publication number Publication date
EP0623019B1 (de) 2000-05-10
FR2698269B1 (fr) 1995-01-06
WO1994012170A3 (fr) 1994-07-21
ES2149253T3 (es) 2000-11-01
WO1994012170A2 (fr) 1994-06-09
EP0623019A1 (de) 1994-11-09
JPH07503488A (ja) 1995-04-13
ATE192647T1 (de) 2000-05-15
DK0623019T3 (da) 2000-10-02
DE69328618T2 (de) 2001-02-01
US5654290A (en) 1997-08-05
FR2698269A1 (fr) 1994-05-27
CA2128706A1 (en) 1994-06-09
CA2128706C (en) 2007-07-10

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee