DE69328618D1 - Medikamente auf der Basis von Docosahexaensäure, als Plättchenaggregationshemmer und gegen cerebralen Mangel an Fettsäuren, und Verfahren zur Herstellung. - Google Patents
Medikamente auf der Basis von Docosahexaensäure, als Plättchenaggregationshemmer und gegen cerebralen Mangel an Fettsäuren, und Verfahren zur Herstellung.Info
- Publication number
- DE69328618D1 DE69328618D1 DE69328618T DE69328618T DE69328618D1 DE 69328618 D1 DE69328618 D1 DE 69328618D1 DE 69328618 T DE69328618 T DE 69328618T DE 69328618 T DE69328618 T DE 69328618T DE 69328618 D1 DE69328618 D1 DE 69328618D1
- Authority
- DE
- Germany
- Prior art keywords
- pct
- dha
- manufacture
- fatty acids
- platelet aggregation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
- A61K31/23—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Epidemiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Urology & Nephrology (AREA)
- Emergency Medicine (AREA)
- Vascular Medicine (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR9214078A FR2698269B1 (fr) | 1992-11-24 | 1992-11-24 | Nouveaux médicaments à base d'acides gras insaturés, utilisables notamment comme antiagrégants plaquettaires et/ou comme transporteurs privilégiés vers le cerveau. |
PCT/FR1993/001158 WO1994012170A2 (fr) | 1992-11-24 | 1993-11-24 | Medicaments a base d'acides gras polyinsatures, notamment d'acides docosahexaenoique comme antiagregants plaquettaires et contre des carences cerebrales en acides gras essentiels. |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69328618D1 true DE69328618D1 (de) | 2000-06-15 |
DE69328618T2 DE69328618T2 (de) | 2001-02-01 |
Family
ID=9435824
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69328618T Expired - Fee Related DE69328618T2 (de) | 1992-11-24 | 1993-11-24 | Medikamente auf der Basis von Docosahexaensäure, als Plättchenaggregationshemmer und gegen cerebralen Mangel an Fettsäuren, und Verfahren zur Herstellung. |
Country Status (10)
Country | Link |
---|---|
US (1) | US5654290A (de) |
EP (1) | EP0623019B1 (de) |
JP (1) | JPH07503488A (de) |
AT (1) | ATE192647T1 (de) |
CA (1) | CA2128706C (de) |
DE (1) | DE69328618T2 (de) |
DK (1) | DK0623019T3 (de) |
ES (1) | ES2149253T3 (de) |
FR (1) | FR2698269B1 (de) |
WO (1) | WO1994012170A2 (de) |
Families Citing this family (24)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6107499A (en) * | 1988-02-26 | 2000-08-22 | Neuromedica, Inc. | Dopamine analog amide |
US5795909A (en) | 1996-05-22 | 1998-08-18 | Neuromedica, Inc. | DHA-pharmaceutical agent conjugates of taxanes |
US6576636B2 (en) | 1996-05-22 | 2003-06-10 | Protarga, Inc. | Method of treating a liver disorder with fatty acid-antiviral agent conjugates |
US6153653A (en) * | 1997-11-26 | 2000-11-28 | Protarga, Inc. | Choline compositions and uses thereof |
US5955459A (en) * | 1997-11-26 | 1999-09-21 | Neuromedica, Inc. | Fatty acid-antipsychotic compositions and uses thereof |
US5977174A (en) * | 1997-11-26 | 1999-11-02 | Neuromedica, Inc. | Cholinergic compositions and uses thereof |
US6197764B1 (en) | 1997-11-26 | 2001-03-06 | Protarga, Inc. | Clozapine compositions and uses thereof |
US6225444B1 (en) | 1998-02-10 | 2001-05-01 | Protarga, Inc. | Neuroprotective peptides and uses thereof |
US7235583B1 (en) * | 1999-03-09 | 2007-06-26 | Luitpold Pharmaceuticals, Inc., | Fatty acid-anticancer conjugates and uses thereof |
JP4634694B2 (ja) | 2001-03-23 | 2011-02-16 | ルイトポルド・ファーマシューティカルズ・インコーポレーテッド | 脂肪アルコール薬物複合体 |
EP1427407A4 (de) | 2001-03-23 | 2005-05-11 | Luitpold Pharm Inc | Fettamin-arzneimittel-konjugate |
IL142952A (en) * | 2001-05-03 | 2005-12-18 | Enzmotec Ltd | Process for enzyme-catalyzed production of 1,2 diacylated phospholipids |
EP1466597A1 (de) * | 2003-04-07 | 2004-10-13 | Clinigenetics | Verwendung von dha-Esteren in der Behandlung kardiovasculärer Krankheiten |
WO2004091603A1 (fr) * | 2003-04-07 | 2004-10-28 | Clinigenetics | Utilisation d’un ester de dha pour le traitement des malades cardiovasculaires |
FR2857265A1 (fr) * | 2003-07-08 | 2005-01-14 | Clinigenetics | Utilisation de lyso-pcdha pour le traitement des maladies cardiovasculaires |
CN1898370A (zh) * | 2003-12-22 | 2007-01-17 | 湧永制药株式会社 | 油脂组合物 |
JP5352961B2 (ja) * | 2006-03-28 | 2013-11-27 | Jnc株式会社 | 生活習慣病予防・治療剤 |
FR2979825B1 (fr) | 2011-09-13 | 2013-11-29 | Inst Nat Sciences Appliq | Phosphatidylcholines specifiques en tant que modulateurs de l'activite du facteur d'activation plaquettaire |
AU2014203179C1 (en) | 2013-06-14 | 2017-05-04 | Aker Biomarine Antarctic As | Lipid extraction processes |
US9233114B2 (en) | 2013-12-05 | 2016-01-12 | Buriva, LLC | Dietary supplement containing phospholipid-DHA derived from eggs |
US9216199B2 (en) | 2013-12-05 | 2015-12-22 | Buriva, LLC | Nutritional supplement containing phospholipid-DHA derived from eggs |
US9549937B2 (en) | 2013-12-05 | 2017-01-24 | Burvia, LLC. | Composition containing phospholipid-DHA and folate |
US9610302B2 (en) | 2013-12-05 | 2017-04-04 | Buriva, LLC. | Composition containing phospholipid-DHA and B vitamins |
SG11202005905TA (en) | 2017-12-21 | 2020-07-29 | Aker Biomarine Antarctic As | Lysophosphatidylcholine compositions |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB2098065A (en) * | 1981-04-14 | 1982-11-17 | Nippon Suisan Kaisha Ltd | Antithrombotic compositions containing docosahexaenoic acid |
IT1223290B (it) * | 1987-07-27 | 1990-09-19 | Indena Spa | Acidi poliinsaturi ad azione vasocinetica e relative formulazioni farmaceutiche e cosmetiche |
JPS6450890A (en) * | 1987-08-20 | 1989-02-27 | Nippon Oils & Fats Co Ltd | Production of docosahexaenoic acid-containing phosphatidyl choline |
JP2537645B2 (ja) * | 1987-11-13 | 1996-09-25 | 雪印乳業株式会社 | 薬剤的活性を有する栄養組成物 |
JPH01203330A (ja) * | 1988-02-05 | 1989-08-16 | Rikagaku Kenkyusho | 制癌剤 |
JP2524217B2 (ja) * | 1988-04-18 | 1996-08-14 | マルハ株式会社 | 脳機能改善組成物、学習能力増強剤、記憶力増強剤、痴呆予防剤または痴呆治療剤 |
GB2218904A (en) * | 1988-05-27 | 1989-11-29 | Renafield Limited | Pharmaceutical composition based on high-concentration esters of docosahexaenoic acid |
IT1230141B (it) * | 1989-05-03 | 1991-10-14 | Fidia Spa | Impiego di derivati della fosfatidil carnitina per la preparazione di composizioni farmaceutiche aventi attivita' nella terapia delle patologie dell'uomo associate con un danno neuronale. |
JPH03178931A (ja) * | 1989-09-08 | 1991-08-02 | Nippon Oil & Fats Co Ltd | 睡眠増加剤 |
JPH0748992B2 (ja) * | 1990-04-16 | 1995-05-31 | 日本油脂株式会社 | 血栓防止用粉末組成物 |
JP3092180B2 (ja) * | 1991-02-27 | 2000-09-25 | 日本油脂株式会社 | 低密度リポ蛋白受容体活性化剤 |
-
1992
- 1992-11-24 FR FR9214078A patent/FR2698269B1/fr not_active Expired - Fee Related
-
1993
- 1993-11-24 CA CA002128706A patent/CA2128706C/en not_active Expired - Fee Related
- 1993-11-24 WO PCT/FR1993/001158 patent/WO1994012170A2/fr active IP Right Grant
- 1993-11-24 ES ES94900873T patent/ES2149253T3/es not_active Expired - Lifetime
- 1993-11-24 DE DE69328618T patent/DE69328618T2/de not_active Expired - Fee Related
- 1993-11-24 EP EP94900873A patent/EP0623019B1/de not_active Expired - Lifetime
- 1993-11-24 US US08/256,825 patent/US5654290A/en not_active Expired - Fee Related
- 1993-11-24 AT AT94900873T patent/ATE192647T1/de not_active IP Right Cessation
- 1993-11-24 DK DK94900873T patent/DK0623019T3/da active
- 1993-11-24 JP JP6512847A patent/JPH07503488A/ja not_active Ceased
Also Published As
Publication number | Publication date |
---|---|
CA2128706A1 (en) | 1994-06-09 |
FR2698269B1 (fr) | 1995-01-06 |
DK0623019T3 (da) | 2000-10-02 |
US5654290A (en) | 1997-08-05 |
ES2149253T3 (es) | 2000-11-01 |
WO1994012170A3 (fr) | 1994-07-21 |
EP0623019B1 (de) | 2000-05-10 |
DE69328618T2 (de) | 2001-02-01 |
ATE192647T1 (de) | 2000-05-15 |
CA2128706C (en) | 2007-07-10 |
JPH07503488A (ja) | 1995-04-13 |
FR2698269A1 (fr) | 1994-05-27 |
EP0623019A1 (de) | 1994-11-09 |
WO1994012170A2 (fr) | 1994-06-09 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee |