DE69328489T2 - Stress-proteine epitopen - Google Patents

Stress-proteine epitopen

Info

Publication number
DE69328489T2
DE69328489T2 DE69328489T DE69328489T DE69328489T2 DE 69328489 T2 DE69328489 T2 DE 69328489T2 DE 69328489 T DE69328489 T DE 69328489T DE 69328489 T DE69328489 T DE 69328489T DE 69328489 T2 DE69328489 T2 DE 69328489T2
Authority
DE
Germany
Prior art keywords
purified
epitope
stress proteins
synthesised
substitution
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69328489T
Other languages
English (en)
Other versions
DE69328489D1 (de
Inventor
Peter Burnie
Christine Matthews
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Neutec Pharma Ltd
Original Assignee
Neutec Pharma Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Neutec Pharma Ltd filed Critical Neutec Pharma Ltd
Publication of DE69328489D1 publication Critical patent/DE69328489D1/de
Application granted granted Critical
Publication of DE69328489T2 publication Critical patent/DE69328489T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/37—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from fungi
    • C07K14/39—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from fungi from yeasts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Genetics & Genomics (AREA)
  • Mycology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Veterinary Medicine (AREA)
  • Microbiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Toxicology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Zoology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Peptides Or Proteins (AREA)
  • Saccharide Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DE69328489T 1992-08-18 1993-08-17 Stress-proteine epitopen Expired - Lifetime DE69328489T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB9217542A GB2270076A (en) 1992-08-18 1992-08-18 Human HSP 90 Epitopes
PCT/GB1993/001745 WO1994004676A1 (en) 1992-08-18 1993-08-17 Stress protein epitopes

Publications (2)

Publication Number Publication Date
DE69328489D1 DE69328489D1 (de) 2000-05-31
DE69328489T2 true DE69328489T2 (de) 2000-11-30

Family

ID=10720544

Family Applications (2)

Application Number Title Priority Date Filing Date
DE69333673T Expired - Lifetime DE69333673T2 (de) 1992-08-18 1993-08-17 Epitope von Stress Proteinen
DE69328489T Expired - Lifetime DE69328489T2 (de) 1992-08-18 1993-08-17 Stress-proteine epitopen

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DE69333673T Expired - Lifetime DE69333673T2 (de) 1992-08-18 1993-08-17 Epitope von Stress Proteinen

Country Status (12)

Country Link
US (1) US5777083A (de)
EP (2) EP0656945B1 (de)
JP (1) JP3439213B2 (de)
AT (2) ATE192192T1 (de)
AU (1) AU4727593A (de)
DE (2) DE69333673T2 (de)
DK (2) DK0861892T3 (de)
ES (2) ES2231907T3 (de)
GB (1) GB2270076A (de)
GR (1) GR3033809T3 (de)
PT (2) PT861892E (de)
WO (1) WO1994004676A1 (de)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10161051B4 (de) * 2001-12-12 2005-09-15 Wieland, Heinrich, Prof. Dr. Diagnose der Malaria

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5750119A (en) * 1994-01-13 1998-05-12 Mount Sinai School Of Medicine Of The City University Of New York Immunotherapeutic stress protein-peptide complexes against cancer
US5997873A (en) 1994-01-13 1999-12-07 Mount Sinai School Of Medicine Of The City University Of New York Method of preparation of heat shock protein 70-peptide complexes
US5961979A (en) * 1994-03-16 1999-10-05 Mount Sinai School Of Medicine Of The City University Of New York Stress protein-peptide complexes as prophylactic and therapeutic vaccines against intracellular pathogens
EP0739981A1 (de) 1995-04-25 1996-10-30 Vrije Universiteit Brussel Variable Fragmente von Immunglobulinen-Verwendung zur therapeutischen oder veterinären Zwecken
US5837251A (en) * 1995-09-13 1998-11-17 Fordham University Compositions and methods using complexes of heat shock proteins and antigenic molecules for the treatment and prevention of neoplastic diseases
US5935576A (en) 1995-09-13 1999-08-10 Fordham University Compositions and methods for the treatment and prevention of neoplastic diseases using heat shock proteins complexed with exogenous antigens
US5985270A (en) * 1995-09-13 1999-11-16 Fordham University Adoptive immunotherapy using macrophages sensitized with heat shock protein-epitope complexes
EP0877620A4 (de) * 1996-01-16 1999-04-14 Rensselaer Polytech Inst Peptide zur veränderung der adhäsionseigenschaften von osteoblasten
US5830464A (en) 1997-02-07 1998-11-03 Fordham University Compositions and methods for the treatment and growth inhibition of cancer using heat shock/stress protein-peptide complexes in combination with adoptive immunotherapy
US6017540A (en) 1997-02-07 2000-01-25 Fordham University Prevention and treatment of primary and metastatic neoplastic diseases and infectious diseases with heat shock/stress protein-peptide complexes
GB9710762D0 (en) * 1997-05-23 1997-07-23 Cancer Res Inst Royal Binding complexes
US5948646A (en) 1997-12-11 1999-09-07 Fordham University Methods for preparation of vaccines against cancer comprising heat shock protein-peptide complexes
EP2295065B1 (de) 1998-02-20 2013-10-09 The University of Miami Modifizierter Hitzeschockprotein-Antigenpeptid-Komplex
GB0008305D0 (en) * 2000-04-06 2000-05-24 Neutec Pharma Plc Treatment of fungal infections
JP2004505894A (ja) 2000-06-02 2004-02-26 ユニバーシティー　オブ　コネティカット　ヘルス　センター 免疫療法のためのα（２）マクログロブリンと抗原分子との複合体
US7491702B2 (en) * 2001-04-18 2009-02-17 The Open University Polypeptides related to amyloid precursor protein, pharmaceutical compositions thereof, and methods of treatment using the same
US7622446B2 (en) * 2001-04-18 2009-11-24 The Open University Polypeptides, derivatives and uses thereof
US6916626B1 (en) * 2001-04-25 2005-07-12 Rockeby Biomed Ltd. Detection of Candida
EP1536829A4 (de) 2001-08-20 2006-05-31 Univ Connecticut Health Ct Verfahren zur herstellung von zusammensetzungen mit hitzeschock-proteinen oder alpha-2-makroglobulin zur behandlung von krebs und infektionskrankheiten
US7959915B2 (en) * 2003-03-12 2011-06-14 Tufts University Inhibitors of extracellular Hsp90
US7807378B2 (en) * 2005-12-29 2010-10-05 Industrial Technology Research Institute (Itri) Method of diagnosing myasthenia gravis and kits therefor
EP1806582B1 (de) * 2006-01-04 2011-05-11 Industrial Technology Research Institute Verfahren zur Diagnose von Myasthenia gravis
JP4283812B2 (ja) * 2006-01-06 2009-06-24 財団法人工業技術研究院 重症筋無力症の診断方法およびそのキット
US20070207992A1 (en) * 2006-02-21 2007-09-06 Board Of Trustees Of Michigan State University Geldanamycin derivatives and method of use thereof
US20100113355A1 (en) 2007-04-27 2010-05-06 Naresh Chennamsetty Novel antibody molecules and nucleic acids binding to fungal stress protein hsp90
JP2011513399A (ja) 2008-03-03 2011-04-28 ザ ユニバーシティー オブ マイアミ 同種癌細胞による免疫療法
WO2009117116A2 (en) 2008-03-20 2009-09-24 University Of Miami Heat shock protein gp96 vaccination and methods of using same
PL2424889T3 (pl) 2009-04-30 2016-01-29 Ablynx Nv Sposób wytwarzania przeciwciał domenowych
MX2017010159A (es) 2015-02-06 2017-12-18 Heat Biologics Inc Vector que expresa conjuntamente vacunas y moléculas coestimuladoras.
CA3040123A1 (en) 2016-10-11 2018-04-19 University Of Miami Vectors and vaccine cells for immunity against zika virus
WO2018187260A1 (en) 2017-04-04 2018-10-11 Heat Biologics, Inc. Intratumoral vaccination

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8915019D0 (en) * 1989-06-30 1989-08-23 Matthews Ruth C Medicaments
US5188964A (en) * 1990-04-12 1993-02-23 Board Of Regents, The University Of Texas System Method and kit for the prognostication of breast cancer patient via heat shock/stress protein determination
GB9016315D0 (en) * 1990-07-25 1990-09-12 Burnie James P Medicaments
DE4201181A1 (de) * 1992-01-17 1993-07-22 Boehringer Mannheim Gmbh Verfahren zur stabilisierung von proteinen

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10161051B4 (de) * 2001-12-12 2005-09-15 Wieland, Heinrich, Prof. Dr. Diagnose der Malaria

Also Published As

Publication number Publication date
PT656945E (pt) 2000-08-31
JP3439213B2 (ja) 2003-08-25
DE69328489D1 (de) 2000-05-31
EP0656945B1 (de) 2000-04-26
GR3033809T3 (en) 2000-10-31
EP0861892A1 (de) 1998-09-02
DE69333673D1 (de) 2004-11-25
DE69333673T2 (de) 2006-03-09
WO1994004676A1 (en) 1994-03-03
PT861892E (pt) 2005-03-31
US5777083A (en) 1998-07-07
GB2270076A (en) 1994-03-02
ES2147560T3 (es) 2000-09-16
AU4727593A (en) 1994-03-15
ATE280227T1 (de) 2004-11-15
JPH08500016A (ja) 1996-01-09
ATE192192T1 (de) 2000-05-15
EP0656945A1 (de) 1995-06-14
ES2231907T3 (es) 2005-05-16
DK0656945T3 (da) 2000-09-11
DK0861892T3 (da) 2005-02-14
EP0861892B1 (de) 2004-10-20
GB9217542D0 (en) 1992-09-30

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Legal Events

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