DE69324595T2 - 7-substituierte oxa-steroid verbindung - Google Patents

7-substituierte oxa-steroid verbindung

Info

Publication number
DE69324595T2
DE69324595T2 DE69324595T DE69324595T DE69324595T2 DE 69324595 T2 DE69324595 T2 DE 69324595T2 DE 69324595 T DE69324595 T DE 69324595T DE 69324595 T DE69324595 T DE 69324595T DE 69324595 T2 DE69324595 T2 DE 69324595T2
Authority
DE
Germany
Prior art keywords
substituted
lower alkyl
amino
steroid
connection
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69324595T
Other languages
English (en)
Other versions
DE69324595D1 (de
Inventor
Naoyuki - - Koizumi
Shigehiro Confort-Mus Takegawa
Shigeki Teikoku Zoki Iwashita
Tomoko Kawachi
Fumiko - Inoue
Seijiro - - Honma
Hiroo - - Takahashi
Manoru Mieda
Kaoru - - Ueda
Kenyu - Shibata
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Aska Pharmaceutical Co Ltd
Original Assignee
Teikoku Hormone Manufacturing Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Teikoku Hormone Manufacturing Co Ltd filed Critical Teikoku Hormone Manufacturing Co Ltd
Application granted granted Critical
Publication of DE69324595D1 publication Critical patent/DE69324595D1/de
Publication of DE69324595T2 publication Critical patent/DE69324595T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J31/00—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J73/00—Steroids in which the cyclopenta[a]hydrophenanthrene skeleton has been modified by substitution of one or two carbon atoms by hetero atoms
    • C07J73/001—Steroids in which the cyclopenta[a]hydrophenanthrene skeleton has been modified by substitution of one or two carbon atoms by hetero atoms by one hetero atom
    • C07J73/005—Steroids in which the cyclopenta[a]hydrophenanthrene skeleton has been modified by substitution of one or two carbon atoms by hetero atoms by one hetero atom by nitrogen as hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/08—Drugs for disorders of the urinary system of the prostate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J73/00—Steroids in which the cyclopenta[a]hydrophenanthrene skeleton has been modified by substitution of one or two carbon atoms by hetero atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J73/00—Steroids in which the cyclopenta[a]hydrophenanthrene skeleton has been modified by substitution of one or two carbon atoms by hetero atoms
    • C07J73/001—Steroids in which the cyclopenta[a]hydrophenanthrene skeleton has been modified by substitution of one or two carbon atoms by hetero atoms by one hetero atom
    • C07J73/003—Steroids in which the cyclopenta[a]hydrophenanthrene skeleton has been modified by substitution of one or two carbon atoms by hetero atoms by one hetero atom by oxygen as hetero atom

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Urology & Nephrology (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DE69324595T 1992-09-30 1993-09-29 7-substituierte oxa-steroid verbindung Expired - Fee Related DE69324595T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP28361692 1992-09-30
PCT/JP1993/001390 WO1994007908A1 (en) 1992-09-30 1993-09-29 Novel 7-substituted oxa- or azasteroid compound

Publications (2)

Publication Number Publication Date
DE69324595D1 DE69324595D1 (de) 1999-05-27
DE69324595T2 true DE69324595T2 (de) 1999-08-19

Family

ID=17667815

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69324595T Expired - Fee Related DE69324595T2 (de) 1992-09-30 1993-09-29 7-substituierte oxa-steroid verbindung

Country Status (18)

Country Link
US (1) US5539127A (de)
EP (1) EP0663402B1 (de)
JP (1) JP3293629B2 (de)
KR (1) KR100231638B1 (de)
AT (1) ATE179179T1 (de)
AU (1) AU665455B2 (de)
CA (1) CA2145643A1 (de)
DE (1) DE69324595T2 (de)
DK (1) DK0663402T3 (de)
ES (1) ES2130284T3 (de)
FI (1) FI114799B (de)
GR (1) GR3030245T3 (de)
HU (1) HU221191B1 (de)
NO (1) NO306066B1 (de)
NZ (1) NZ256130A (de)
PL (1) PL176114B1 (de)
SG (1) SG48172A1 (de)
WO (1) WO1994007908A1 (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5245275A (en) * 1989-09-25 1993-09-14 General Electric Company Electronic watthour meter
DE19610645A1 (de) * 1996-03-06 1997-09-11 Schering Ag Kombination von Dehydroepiandrosteron und Aromatasehemmern und Verwendung dieser Kombination zur Herstellung eines Arzeimittels zur Behandlung eines relativen und absoluten Androgenmangels beim Mann
US7880035B2 (en) * 2007-03-01 2011-02-01 Basf Se Method for producing ethyleneamines

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4116978A (en) * 1977-07-20 1978-09-26 E. R. Squibb & Sons, Inc. D-homo oxasteroids
US4235893A (en) * 1978-05-08 1980-11-25 Brodie Angela M Ester derivatives of 4-hydroxy-4-androstene-3,17-dione and a method for inhibiting estrogen biosynthesis
DE3322285A1 (de) * 1983-06-18 1984-12-20 Schering AG, 1000 Berlin und 4709 Bergkamen 1-alkyl-androsta-1,4-dien-3,17-dione, verfahren zu deren herstellung und diese enthaltende pharmazeutische praeparate
GB8503940D0 (en) * 1985-02-15 1985-03-20 Erba Farmitalia 4-substituted androstendione derivatives
DE3622841C2 (de) * 1985-07-09 2001-01-25 Pharmacia & Upjohn Spa Substituierte Androsta-1,4-dien-3,17-dione und Verfahren zu deren Herstellung
GB8517360D0 (en) * 1985-07-09 1985-08-14 Erba Farmitalia Substituted androsta-1,4-diene-3,17-diones
US5227375A (en) * 1990-02-08 1993-07-13 Endorecherche, Inc. Aromatase inhibitors
US5219879A (en) * 1990-03-05 1993-06-15 Du Pont Merck Pharmaceutical Company Heterocyclic steroid compounds
KR0180008B1 (ko) * 1991-03-28 1999-04-01 야마구찌 다까시 신규 옥사-또는 아자스테로이드 유체
JPH05148294A (ja) * 1991-11-27 1993-06-15 Teikoku Hormone Mfg Co Ltd ３，５−ジエンステロイド誘導体

Also Published As

Publication number Publication date
KR100231638B1 (ko) 1999-12-01
EP0663402A4 (de) 1996-06-12
HU9500929D0 (en) 1995-05-29
NO951211D0 (no) 1995-03-29
PL176114B1 (pl) 1999-04-30
JP3293629B2 (ja) 2002-06-17
EP0663402A1 (de) 1995-07-19
AU665455B2 (en) 1996-01-04
DK0663402T3 (da) 1999-10-25
FI951505A (fi) 1995-05-26
KR950703575A (ko) 1995-09-20
DE69324595D1 (de) 1999-05-27
GR3030245T3 (en) 1999-08-31
HUT71519A (en) 1995-12-28
NO306066B1 (no) 1999-09-13
ES2130284T3 (es) 1999-07-01
US5539127A (en) 1996-07-23
SG48172A1 (en) 1998-04-17
EP0663402B1 (de) 1999-04-21
FI951505A0 (fi) 1995-03-29
AU4834293A (en) 1994-04-26
PL308228A1 (en) 1995-07-24
HU221191B1 (en) 2002-08-28
WO1994007908A1 (en) 1994-04-14
ATE179179T1 (de) 1999-05-15
CA2145643A1 (en) 1994-04-14
NO951211L (no) 1995-05-30
FI114799B (fi) 2004-12-31
NZ256130A (en) 1996-05-28

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee