DE69322750D1 - Dibekacin und Arbekacin Derivate wirksam gegen resistente Bakterien, und ihre Herstellung - Google Patents
Dibekacin und Arbekacin Derivate wirksam gegen resistente Bakterien, und ihre HerstellungInfo
- Publication number
- DE69322750D1 DE69322750D1 DE69322750T DE69322750T DE69322750D1 DE 69322750 D1 DE69322750 D1 DE 69322750D1 DE 69322750 T DE69322750 T DE 69322750T DE 69322750 T DE69322750 T DE 69322750T DE 69322750 D1 DE69322750 D1 DE 69322750D1
- Authority
- DE
- Germany
- Prior art keywords
- dibekacin
- manufacture
- effective against
- resistant bacteria
- against resistant
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 241000894006 Bacteria Species 0.000 title 1
- MKKYBZZTJQGVCD-XTCKQBCOSA-N arbekacin Chemical class O([C@@H]1[C@@H](N)C[C@H]([C@@H]([C@H]1O)O[C@@H]1[C@@H]([C@@H](N)[C@H](O)[C@@H](CO)O1)O)NC(=O)[C@@H](O)CCN)[C@H]1O[C@H](CN)CC[C@H]1N MKKYBZZTJQGVCD-XTCKQBCOSA-N 0.000 title 1
- JJCQSGDBDPYCEO-XVZSLQNASA-N dibekacin Chemical compound O1[C@H](CN)CC[C@@H](N)[C@H]1O[C@H]1[C@H](O)[C@@H](O[C@@H]2[C@@H]([C@@H](N)[C@H](O)[C@@H](CO)O2)O)[C@H](N)C[C@@H]1N JJCQSGDBDPYCEO-XVZSLQNASA-N 0.000 title 1
- 229960003807 dibekacin Drugs 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/20—Carbocyclic rings
- C07H15/22—Cyclohexane rings, substituted by nitrogen atoms
- C07H15/222—Cyclohexane rings substituted by at least two nitrogen atoms
- C07H15/226—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings
- C07H15/234—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings attached to non-adjacent ring carbon atoms of the cyclohexane rings, e.g. kanamycins, tobramycin, nebramycin, gentamicin A2
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP34131492A JP3215732B2 (ja) | 1992-11-27 | 1992-11-27 | 耐性菌に有効なジベカシン誘導体またはアルベカシン誘導体とそれらの製造法 |
| JP24732793A JP3215759B2 (ja) | 1993-09-09 | 1993-09-09 | 耐性菌に有効な５−置換−２″−アミノ−２″−デオキシアルベカシンとその製造法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE69322750D1 true DE69322750D1 (de) | 1999-02-04 |
| DE69322750T2 DE69322750T2 (de) | 1999-08-19 |
Family
ID=26538214
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE69322750T Expired - Fee Related DE69322750T2 (de) | 1992-11-27 | 1993-11-26 | Dibekacin und Arbekacin Derivate wirksam gegen resistente Bakterien, und ihre Herstellung |
Country Status (4)
| Country | Link |
|---|---|
| US (2) | US5488038A (de) |
| EP (1) | EP0601909B1 (de) |
| DE (1) | DE69322750T2 (de) |
| ES (1) | ES2128404T3 (de) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20040058880A1 (en) * | 2002-07-01 | 2004-03-25 | Chang-Hsing Liang | Aminoglycoside antibiotics as novel anti-infective agents |
| WO2005070945A1 (ja) * | 2004-01-21 | 2005-08-04 | Meiji Seika Kaisha, Ltd. | メチシリン耐性黄色ブドウ球菌（ｍｒｓａ）に有効な新規アミノグリコシド系抗生物質 |
| US7794713B2 (en) * | 2004-04-07 | 2010-09-14 | Lpath, Inc. | Compositions and methods for the treatment and prevention of hyperproliferative diseases |
| PT2316419E (pt) | 2004-05-17 | 2012-10-22 | Gilead Sciences Inc | Combinação de fosfomicina/aminoglicósido em aerossol para o tratamento de infeções respiratórias bacterianas |
| GB0411948D0 (en) * | 2004-05-28 | 2004-06-30 | Univ Leeds | Compounds |
| JP5034946B2 (ja) * | 2005-08-29 | 2012-09-26 | 味の素株式会社 | 栄養組成物 |
| US20080213274A1 (en) * | 2005-10-28 | 2008-09-04 | Sabbadini Roger A | Compositions and methods for the treatment and prevention of fibrotic, inflammatory, and neovascularization conditions of the eye |
| US20090074720A1 (en) * | 2005-10-28 | 2009-03-19 | Sabbadini Roger A | Methods for decreasing immune response and treating immune conditions |
| US7862812B2 (en) * | 2006-05-31 | 2011-01-04 | Lpath, Inc. | Methods for decreasing immune response and treating immune conditions |
| AU2009299118B2 (en) | 2008-10-03 | 2015-12-17 | Glycan Biosciences Llc | Anionic conjugates of glycosylated bacterial metabolite |
| AU2011211744B2 (en) * | 2010-02-03 | 2015-06-18 | Microbial Chemistry Research Foundation | Read through inducer, and therapeutic agent for nonsense-mutation-type genetic diseases |
| CN116462721B (zh) * | 2023-04-18 | 2024-02-02 | 江南大学 | 抗菌性氨基糖苷衍生物 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4001208A (en) | 1972-10-06 | 1977-01-04 | Zaidan Hojin Biseibutsu Kagaku Kenkyo Kai | 1-N-[(S)-α-hydroxy-ω-aminoacyl] |
| US4107424A (en) * | 1972-10-06 | 1978-08-15 | Zaidan Hojin Biseibutsu Kagaku Kenkyu Kai | 1-N-[(S)-α-hydroxy-ω-aminoacyl] derivatives of 3',4'-dideoxykanamycin B and 3'-deoxykanamycin B antibiotics |
| US3974198A (en) | 1975-09-02 | 1976-08-10 | General Electric Company | Process for producing methyltriacetoxysilane |
| JPS6029720B2 (ja) * | 1975-12-11 | 1985-07-12 | 財団法人微生物化学研究会 | ３′，４′‐ジデオキシカナマイシンｂの新規な製造法 |
| US4187372A (en) * | 1976-09-08 | 1980-02-05 | Abbott Laboratories | Seldomycin factor 5 derivative |
| IE48972B1 (en) | 1978-11-11 | 1985-06-26 | Microbial Chem Res Found | The production of a selectively protected n-acylated derivative of an aminoglycosidic antibiotic |
| JPS631319A (ja) | 1986-06-18 | 1988-01-06 | 多摩川精機株式会社 | Ａｃ機器動作検出回路 |
| JPS6339891A (ja) * | 1986-08-04 | 1988-02-20 | Microbial Chem Res Found | ５−デオキシ−５−フルオロカナマイシンｂ誘導体とその製造法 |
| JPH0764866B2 (ja) * | 1987-02-24 | 1995-07-12 | 財団法人微生物化学研究会 | １−ｎ−（４−アミノ−３−フルオロ−２−ヒドロキシブチリル）カナマイシン類 |
-
1993
- 1993-11-18 US US08/154,002 patent/US5488038A/en not_active Expired - Lifetime
- 1993-11-26 EP EP93402870A patent/EP0601909B1/de not_active Expired - Lifetime
- 1993-11-26 ES ES93402870T patent/ES2128404T3/es not_active Expired - Lifetime
- 1993-11-26 DE DE69322750T patent/DE69322750T2/de not_active Expired - Fee Related
-
1995
- 1995-09-08 US US08/524,644 patent/US5618795A/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| EP0601909A3 (en) | 1997-03-19 |
| EP0601909B1 (de) | 1998-12-23 |
| ES2128404T3 (es) | 1999-05-16 |
| DE69322750T2 (de) | 1999-08-19 |
| US5488038A (en) | 1996-01-30 |
| EP0601909A2 (de) | 1994-06-15 |
| US5618795A (en) | 1997-04-08 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition | ||
| 8339 | Ceased/non-payment of the annual fee |