DE69320961T2 - Glutathion analoge und paraloge Serien aus Glutathion imitierenden Stoffen - Google Patents

Glutathion analoge und paraloge Serien aus Glutathion imitierenden Stoffen

Info

Publication number
DE69320961T2
DE69320961T2 DE69320961T DE69320961T DE69320961T2 DE 69320961 T2 DE69320961 T2 DE 69320961T2 DE 69320961 T DE69320961 T DE 69320961T DE 69320961 T DE69320961 T DE 69320961T DE 69320961 T2 DE69320961 T2 DE 69320961T2
Authority
DE
Germany
Prior art keywords
glutathione
paralogue
imitating
substances
chem
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69320961T
Other languages
English (en)
Other versions
DE69320961D1 (de
Inventor
Lawrence Kauvar
Matthew Lyttle
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Telik Inc
Original Assignee
Telik Inc
Terrapin Technologies Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Telik Inc, Terrapin Technologies Inc filed Critical Telik Inc
Application granted granted Critical
Publication of DE69320961D1 publication Critical patent/DE69320961D1/de
Publication of DE69320961T2 publication Critical patent/DE69320961T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/0215—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing natural amino acids, forming a peptide bond via their side chain functional group, e.g. epsilon-Lys, gamma-Glu
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Biophysics (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biotechnology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Microbiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Detergent Compositions (AREA)
  • Confectionery (AREA)
  • Cosmetics (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
DE69320961T 1993-09-03 1993-09-28 Glutathion analoge und paraloge Serien aus Glutathion imitierenden Stoffen Expired - Lifetime DE69320961T2 (de)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
CA002105492A CA2105492C (en) 1993-09-03 1993-09-03 Glutathione analogs and paralog panels comprising glutathione mimics
EP93307676A EP0645397B1 (de) 1993-09-03 1993-09-28 Glutathion analoge und paraloge Serien aus Glutathion imitierenden Stoffen
AU48733/93A AU671855B2 (en) 1993-09-03 1993-09-30 Novel glutathione analogs and paralog panels comprising glutathione mimics
JP24723893A JP3542040B2 (ja) 1993-09-03 1993-10-01 グルタチオン模倣体を含有する新規グルタチオンアナログおよびパラログパネル

Publications (2)

Publication Number Publication Date
DE69320961D1 DE69320961D1 (de) 1998-10-15
DE69320961T2 true DE69320961T2 (de) 1999-01-28

Family

ID=27423327

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69320961T Expired - Lifetime DE69320961T2 (de) 1993-09-03 1993-09-28 Glutathion analoge und paraloge Serien aus Glutathion imitierenden Stoffen

Country Status (8)

Country Link
EP (1) EP0645397B1 (de)
JP (1) JP3542040B2 (de)
AT (1) ATE170869T1 (de)
AU (1) AU671855B2 (de)
CA (1) CA2105492C (de)
DE (1) DE69320961T2 (de)
DK (1) DK0645397T3 (de)
ES (1) ES2120485T3 (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2794122B1 (fr) * 1999-05-27 2001-09-07 Centre Nat Rech Scient Nouveaux antioxydants, procedes de preparation et utilisations
US7172905B2 (en) 2001-08-07 2007-02-06 The University Of Chicago Polypeptide immobilization
NZ555362A (en) * 2005-01-06 2009-05-31 Telik Inc Tripeptide and tetrapeptide thioethers

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS61162175A (ja) * 1985-01-11 1986-07-22 Kiyomi Sato グルタチオン−ｓ−トランスフエラ−ゼの精製法
US5133866A (en) 1988-03-24 1992-07-28 Terrapin Technologies, Inc. Method to identify analyte-bending ligands
WO1992019767A1 (en) * 1991-04-29 1992-11-12 Terrapin Technologies, Inc. Methods to profile and treat abnormal cells

Also Published As

Publication number Publication date
ES2120485T3 (es) 1998-11-01
JP3542040B2 (ja) 2004-07-14
EP0645397A1 (de) 1995-03-29
JPH07145142A (ja) 1995-06-06
CA2105492A1 (en) 1995-03-04
DK0645397T3 (da) 1999-03-01
EP0645397B1 (de) 1998-09-09
AU671855B2 (en) 1996-09-12
AU4873393A (en) 1995-05-04
CA2105492C (en) 2000-02-01
ATE170869T1 (de) 1998-09-15
DE69320961D1 (de) 1998-10-15

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Legal Events

Date Code Title Description
8327 Change in the person/name/address of the patent owner

Owner name: TELIK INC., SOUTH SAN FRANCISCO, CALIF., US

8364 No opposition during term of opposition