DE69310207D1 - Methode zum Nachweis von unweltbedingten Vergehen - Google Patents

Methode zum Nachweis von unweltbedingten Vergehen

Info

Publication number
DE69310207D1
DE69310207D1 DE69310207T DE69310207T DE69310207D1 DE 69310207 D1 DE69310207 D1 DE 69310207D1 DE 69310207 T DE69310207 T DE 69310207T DE 69310207 T DE69310207 T DE 69310207T DE 69310207 D1 DE69310207 D1 DE 69310207D1
Authority
DE
Germany
Prior art keywords
pct
stress
environmental
environmental stress
sec
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69310207T
Other languages
English (en)
Other versions
DE69310207T2 (de
DE69310207T3 (de
Inventor
Robert Larossa
William Majarian
Dyk Tina Van
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
EIDP Inc
Original Assignee
EI Du Pont de Nemours and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26743124&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE69310207(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by EI Du Pont de Nemours and Co filed Critical EI Du Pont de Nemours and Co
Application granted granted Critical
Publication of DE69310207D1 publication Critical patent/DE69310207D1/de
Publication of DE69310207T2 publication Critical patent/DE69310207T2/de
Publication of DE69310207T3 publication Critical patent/DE69310207T3/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0069—Oxidoreductases (1.) acting on single donors with incorporation of molecular oxygen, i.e. oxygenases (1.13)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/70—Vectors or expression systems specially adapted for E. coli
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
    • C12Q1/025—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/66—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving luciferase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6897—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids involving reporter genes operably linked to promoters

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Plant Pathology (AREA)
  • Toxicology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Measuring And Recording Apparatus For Diagnosis (AREA)
  • Investigating Or Analyzing Materials By The Use Of Fluid Adsorption Or Reactions (AREA)
DE69310207T 1992-12-04 1993-12-02 Methode zum Nachweis von unweltbedingten Vergehen Expired - Fee Related DE69310207T3 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US98842892A 1992-12-04 1992-12-04
US6317393A 1993-05-14 1993-05-14
PCT/US1993/011527 WO1994013831A1 (en) 1992-12-04 1993-12-02 A highly sensitive method for detecting environmental insults

Publications (3)

Publication Number Publication Date
DE69310207D1 true DE69310207D1 (de) 1997-05-28
DE69310207T2 DE69310207T2 (de) 1997-08-14
DE69310207T3 DE69310207T3 (de) 2001-11-15

Family

ID=26743124

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69310207T Expired - Fee Related DE69310207T3 (de) 1992-12-04 1993-12-02 Methode zum Nachweis von unweltbedingten Vergehen

Country Status (11)

Country Link
US (1) US5683868A (de)
EP (1) EP0673439B2 (de)
JP (1) JPH08504101A (de)
KR (1) KR100262681B1 (de)
AT (1) ATE152181T1 (de)
AU (1) AU5730494A (de)
CA (1) CA2150232C (de)
DE (1) DE69310207T3 (de)
ES (1) ES2102811T5 (de)
IL (2) IL107815A (de)
WO (1) WO1994013831A1 (de)

Families Citing this family (35)

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Publication number Priority date Publication date Assignee Title
ATE222605T1 (de) * 1994-11-23 2002-09-15 Du Pont Bioluminiscente lyophilisierte bakterien-reagenz zur giftstoff nachweit
EP0907748B1 (de) 1996-04-25 2013-06-12 "VLAAMSE INSTELLING VOOR TECHNOLOGISCH ONDERZOEK", afgekort "V.I.T.O." Rekombinante nukleinsäuresequenzen und methoden für die bestimmung der gentoxizität und mutagenität einer probe sowie der kinetik der gentoxizität
US5817463A (en) * 1996-06-28 1998-10-06 Abbott Laboratories Nucleic acid primers and probes for detecting Mycoplasma pneumoniae
AUPO128096A0 (en) * 1996-07-29 1996-08-22 Crc For Waste Management And Pollution Control Limited Biosensors
US6025131A (en) * 1996-10-23 2000-02-15 E. I. Du Pont De Namours And Company Facile method for identifying regulated promoters
EP0943000A1 (de) * 1996-11-15 1999-09-22 E.I. Du Pont De Nemours And Company Hochsensitive methode zum nachweis von schädlichen umwelteinflüssen unter verwendung kleiner probenvolumina
IL131336A0 (en) * 1997-02-28 2001-01-28 Du Pont A method for identifying the site of action of xenobiotic chemicals
GB9713666D0 (en) 1997-06-27 1997-09-03 Univ Cambridge Tech Biosensor materials and methods
EP1023434A4 (de) * 1997-09-18 2004-12-01 Smithkline Beecham Corp Verfahren zum finden von antimikrobiellen verbindungen
EP1060268A2 (de) * 1998-03-06 2000-12-20 E.I. Du Pont De Nemours And Company Verfahren zur identifizierung von polykationischen, peptidartigen verbindungen mit antibakteriellen wirkung
US6703211B1 (en) * 1998-03-13 2004-03-09 Promega Corporation Cellular detection by providing high energy phosphate donor other than ADP to produce ATP
EP0950717A1 (de) * 1998-04-14 1999-10-20 "VLAAMSE INSTELLING VOOR TECHNOLOGISCH ONDERZOEK", afgekort "V.I.T.O." Diagnostisches System und Verfahren zur Bestimmung genotoxischer Substanzen in einer Probe
GB9819666D0 (en) * 1998-09-09 1998-11-04 Univ Aberdeen Biosensor
US6720415B2 (en) * 1998-12-02 2004-04-13 Princeton University Compositions and methods for regulating bacterial pathogenesis
US6602666B2 (en) 1998-12-02 2003-08-05 Vlaamse Instelling Technologisch Onderzoek (V.I.T.O.) Recombinant nucleic acid sequences and methods for determining both genotoxicity and mutagenicity of a sample and the kinetics of the genotoxicity
US6677431B2 (en) 1999-12-10 2004-01-13 The Trustees Of The University Of Pennsylvania Design, preparation, and properties of antibacterial β-peptides
GB0000908D0 (en) * 2000-01-14 2000-03-08 Scient Generics Ltd Parallel free-space optical communications
KR100414784B1 (ko) * 2000-01-18 2004-01-13 (주)바이오니아 연속식 수질 독성 검사 장치
KR100377539B1 (ko) * 2000-04-06 2003-03-26 광주과학기술원 식품내 잔류하는 농약에 대한 발광미생물을 이용한 독성탐지방법
US6716582B2 (en) * 2000-04-14 2004-04-06 E. I. Du Pont De Nemours And Company Cellular arrays for the identification of altered gene expression
KR20020041603A (ko) * 2000-11-28 2002-06-03 박호군 발광유전자 ｌｕｘＣＤＡＢＥ를 포함하는 재조합플라스미드, 이 플라스미드에 의해 형질 전환된 대장균ＳＢ０１(ＫＦＣＣ １１１７６) 및 이의 용도
CA2365791A1 (en) 2000-12-22 2002-06-22 Pfizer Products Inc. Novel bioluminescent assays and bacterial strains useful therein
AU2002252370A1 (en) * 2001-03-12 2002-09-24 Irm, Llc. Genomics-driven high speed cellular assays, development thereof, and collections of cellular reporters
DE10138766A1 (de) * 2001-08-07 2003-02-20 Bayer Cropscience Ag Verfahren zum Identifizieren von makrocyclischen Polyketiden
DE10242433A1 (de) * 2002-09-11 2004-03-25 Henkel Kgaa DNA-Chips zur Bioprozeßkontrolle
WO2005017198A2 (en) * 2003-08-18 2005-02-24 Aic Surface display expression system
WO2006018049A1 (en) * 2004-08-18 2006-02-23 Aic Surface display expression system
WO2006096063A1 (en) * 2005-03-11 2006-09-14 Stichting Voor De Technische Wetenschappen Construct and method for screening, selection and identification of stress factors
KR100697245B1 (ko) 2005-03-28 2007-03-21 한국생명공학연구원 중금속 유도성 프로모터와 이의 생물공학적 활용
US20080268488A1 (en) * 2005-11-10 2008-10-30 Sturgess Michael A Screening Method for Dnak Inhibitors
KR100749493B1 (ko) 2006-03-22 2007-08-14 한국원자력연구원 대장균에서 ｒｐｏＳ 유전자의 발현을 조절함으로서프로피온산에 대한 미생물 감수성을 증진시키는 방법
US8647642B2 (en) 2008-09-18 2014-02-11 Aviex Technologies, Llc Live bacterial vaccines resistant to carbon dioxide (CO2), acidic PH and/or osmolarity for viral infection prophylaxis or treatment
WO2013052237A2 (en) * 2011-09-08 2013-04-11 Attagene, Inc. Systems and methods for assay of bio-contaminants in water
US11129906B1 (en) 2016-12-07 2021-09-28 David Gordon Bermudes Chimeric protein toxins for expression by therapeutic bacteria
US11180535B1 (en) 2016-12-07 2021-11-23 David Gordon Bermudes Saccharide binding, tumor penetration, and cytotoxic antitumor chimeric peptides from therapeutic bacteria

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4581335A (en) * 1982-12-01 1986-04-08 Texas A&M University System Process for producing a cloned luciferase-synthesizing microorganism
US5221623A (en) * 1986-07-22 1993-06-22 Boyce Thompson Institute For Plant Research, Inc. Use of bacterial luciferase structural genes for cloning and monitoring gene expression in microorganisms and for tagging and identification of genetically engineered organisms
US5232833A (en) * 1988-09-14 1993-08-03 Stressgen Biotechnologies Corporation Accumulation of heat shock proteins for evaluating biological damage due to chronic exposure of an organism to sublethal levels of pollutants
DE3833628A1 (de) * 1988-10-03 1990-04-12 Genlux Forschungsgesellschaft Verfahren zum nachweis und zur identifikation toxischer substanzen mit hilfe klonierter mikroorganismen
DE3902982A1 (de) * 1989-02-01 1990-08-02 Genlux Forschungsgesellschaft Verfahren zum nachweis von quecksilber mit hilfe von durch quecksilber zu erhoehter biolumineszenz angeregter mikroorganismen
CA2105172C (en) * 1991-03-01 2002-10-15 Philippe Corbisier Fused genes and their use for determining the presence of metals or of xenobiotic compounds
WO1993003179A1 (en) * 1991-07-30 1993-02-18 Bio-Technical Resources Device for detecting aqueous contaminants
KR100300932B1 (ko) * 1992-07-06 2001-10-22 조이스 브린톤 리포터유전자에융합된세균의스트레스프로모터를이용하여독성을측정하는방법및진단키트

Also Published As

Publication number Publication date
IL139794A0 (en) 2002-02-10
ATE152181T1 (de) 1997-05-15
EP0673439A1 (de) 1995-09-27
JPH08504101A (ja) 1996-05-07
ES2102811T3 (es) 1997-08-01
DE69310207T2 (de) 1997-08-14
EP0673439B1 (de) 1997-04-23
US5683868A (en) 1997-11-04
IL107815A0 (en) 1994-04-12
IL107815A (en) 2003-12-10
DE69310207T3 (de) 2001-11-15
AU5730494A (en) 1994-07-04
WO1994013831A1 (en) 1994-06-23
KR950704511A (ko) 1995-11-20
CA2150232C (en) 2000-12-19
KR100262681B1 (ko) 2000-08-01
CA2150232A1 (en) 1994-06-23
ES2102811T5 (es) 2001-10-16
EP0673439B2 (de) 2001-07-04

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Legal Events

Date Code Title Description
8363 Opposition against the patent
8366 Restricted maintained after opposition proceedings
8339 Ceased/non-payment of the annual fee