DE69309435D1 - Restenosehemmer nach perkutaner koronarer arterioplastie - Google Patents

Restenosehemmer nach perkutaner koronarer arterioplastie

Info

Publication number
DE69309435D1
DE69309435D1 DE69309435T DE69309435T DE69309435D1 DE 69309435 D1 DE69309435 D1 DE 69309435D1 DE 69309435 T DE69309435 T DE 69309435T DE 69309435 T DE69309435 T DE 69309435T DE 69309435 D1 DE69309435 D1 DE 69309435D1
Authority
DE
Germany
Prior art keywords
percutaneous coronary
substituted
alkyl
alternatively
restenose
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69309435T
Other languages
English (en)
Other versions
DE69309435T2 (de
Inventor
Kazuhisa Kodama
Atsushi Hirayama
Hiroyuki Daiichi Phar Masayasu
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Daiichi Pharmaceutical Co Ltd
Original Assignee
Daiichi Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Daiichi Pharmaceutical Co Ltd filed Critical Daiichi Pharmaceutical Co Ltd
Application granted granted Critical
Publication of DE69309435D1 publication Critical patent/DE69309435D1/de
Publication of DE69309435T2 publication Critical patent/DE69309435T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/06—Tripeptides
    • A61K38/063—Glutathione
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/28—Compounds containing heavy metals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/357—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having two or more oxygen atoms in the same ring, e.g. crown ethers, guanadrel
    • A61K31/36—Compounds containing methylenedioxyphenyl groups, e.g. sesamin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/555—Heterocyclic compounds containing heavy metals, e.g. hemin, hematin, melarsoprol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DE69309435T 1992-01-17 1993-01-14 Restenosehemmer nach perkutaner koronarer arterioplastie Expired - Fee Related DE69309435T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP655292 1992-01-17
PCT/JP1993/000045 WO1993013762A1 (en) 1992-01-17 1993-01-14 Inhibitor for restenosis after percutaneous coronary arterioplasty

Publications (2)

Publication Number Publication Date
DE69309435D1 true DE69309435D1 (de) 1997-05-07
DE69309435T2 DE69309435T2 (de) 1997-07-10

Family

ID=11641498

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69309435T Expired - Fee Related DE69309435T2 (de) 1992-01-17 1993-01-14 Restenosehemmer nach perkutaner koronarer arterioplastie

Country Status (11)

Country Link
US (1) US5480888A (de)
EP (1) EP0622076B1 (de)
JP (1) JPH05255084A (de)
KR (1) KR100214453B1 (de)
AT (1) ATE150964T1 (de)
CA (1) CA2126465C (de)
DE (1) DE69309435T2 (de)
DK (1) DK0622076T3 (de)
ES (1) ES2100520T3 (de)
GR (1) GR3023308T3 (de)
WO (1) WO1993013762A1 (de)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6515009B1 (en) 1991-09-27 2003-02-04 Neorx Corporation Therapeutic inhibitor of vascular smooth muscle cells
US5811447A (en) 1993-01-28 1998-09-22 Neorx Corporation Therapeutic inhibitor of vascular smooth muscle cells
US6306421B1 (en) 1992-09-25 2001-10-23 Neorx Corporation Therapeutic inhibitor of vascular smooth muscle cells
US5770609A (en) 1993-01-28 1998-06-23 Neorx Corporation Prevention and treatment of cardiovascular pathologies
US6251920B1 (en) 1993-05-13 2001-06-26 Neorx Corporation Prevention and treatment of cardiovascular pathologies
US6395494B1 (en) 1993-05-13 2002-05-28 Neorx Corporation Method to determine TGF-β
US6663881B2 (en) 1993-01-28 2003-12-16 Neorx Corporation Therapeutic inhibitor of vascular smooth muscle cells
US5981568A (en) 1993-01-28 1999-11-09 Neorx Corporation Therapeutic inhibitor of vascular smooth muscle cells
US6491938B2 (en) 1993-05-13 2002-12-10 Neorx Corporation Therapeutic inhibitor of vascular smooth muscle cells
WO1994026303A1 (en) 1993-05-13 1994-11-24 Neorx Corporation Prevention and treatment of pathologies associated with abnormally proliferative smooth muscle cells
US5824644A (en) * 1994-07-07 1998-10-20 G. D. Searle & Co. Method of attenuating arterial stenosis
US20030083733A1 (en) * 1997-10-10 2003-05-01 Neorx Corporation Therapeutic inhibitor of vascular smooth muscle cells
US5837313A (en) * 1995-04-19 1998-11-17 Schneider (Usa) Inc Drug release stent coating process
US20020091433A1 (en) * 1995-04-19 2002-07-11 Ni Ding Drug release coated stent
US6099562A (en) * 1996-06-13 2000-08-08 Schneider (Usa) Inc. Drug coating with topcoat
AU5513796A (en) * 1995-04-25 1996-11-18 Daiichi Pharmaceutical Co., Ltd. Remedy for acquired immunodeficiency syndrome
CA2223595C (en) 1995-06-07 2008-08-05 Neorx Corporation Prevention and treatment of cardiovascular pathologies with tamoxifen analogues
TW565558B (en) 1995-11-09 2003-12-11 Chugai Pharmaceutical Co Ltd Intimal thickening inhibitory agent
US6117911A (en) * 1997-04-11 2000-09-12 Neorx Corporation Compounds and therapies for the prevention of vascular and non-vascular pathologies
US7671211B1 (en) 1999-03-31 2010-03-02 Arne Holmgren Substrates for thioredoxin reductase
US6613083B2 (en) * 2001-05-02 2003-09-02 Eckhard Alt Stent device and method
US7776925B2 (en) * 2002-03-06 2010-08-17 Duke University Reversing, postponing or preventing the occurrence of GTN tolerance and/or generation of reactive oxygen species from mitochondria
US10058542B1 (en) 2014-09-12 2018-08-28 Thioredoxin Systems Ab Composition comprising selenazol or thiazolone derivatives and silver and method of treatment therewith

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3407511A1 (de) * 1984-03-01 1985-09-05 A. Nattermann & Cie GmbH, 5000 Köln Benzisoselenazolthione, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische praeparate
DE3422962A1 (de) * 1984-06-22 1986-01-02 A. Nattermann & Cie GmbH, 5000 Köln Glutathion-derivate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische praeparate
EP0165534B1 (de) * 1984-06-22 1989-03-15 A. Nattermann & Cie. GmbH S-(Carbamoyl-phenylselenyl)-Derivate des Glutathions und von Aminomercaptocarbonsäuren, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Präparate
DE3443467A1 (de) * 1984-11-29 1986-05-28 A. Nattermann & Cie GmbH, 5000 Köln Mercaptanderivate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische praeparate
EP0198277B1 (de) * 1985-04-12 1989-05-03 A. Nattermann & Cie. GmbH Diselenobis-benzoesäureamide primärer und sekundärer Amine, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Präparate
DE3626554A1 (de) * 1986-08-06 1988-02-18 Nattermann A & Cie Diselenobis-benzoesaeureamide primaerer heterocyclischer amine, verfahren zur ihrer herstellung und diese enthaltende pharmazeutische praeparate
JP2710633B2 (ja) * 1987-08-28 1998-02-10 第一製薬株式会社 心臓疾患治療剤
JP2596970B2 (ja) * 1988-05-23 1997-04-02 第一製薬株式会社 白血球の粘着又は凝集抑制剤
US5187105A (en) * 1988-07-01 1993-02-16 Miles Inc. Process for determining thiols using chromogenic benzoisothiazolone derivatives
DE3937169A1 (de) * 1989-11-08 1991-05-16 Nattermann A & Cie Benzylselenobenzamide von anilinen und benzylaminen

Also Published As

Publication number Publication date
ATE150964T1 (de) 1997-04-15
JPH05255084A (ja) 1993-10-05
WO1993013762A1 (en) 1993-07-22
EP0622076A4 (de) 1994-12-21
CA2126465C (en) 2002-03-05
DK0622076T3 (da) 1997-06-02
GR3023308T3 (en) 1997-08-29
ES2100520T3 (es) 1997-06-16
DE69309435T2 (de) 1997-07-10
KR100214453B1 (ko) 1999-08-02
EP0622076A1 (de) 1994-11-02
CA2126465A1 (en) 1993-07-22
EP0622076B1 (de) 1997-04-02
US5480888A (en) 1996-01-02

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee