DE69307899T2 - Antiproliferative oligomere - Google Patents
Antiproliferative oligomereInfo
- Publication number
- DE69307899T2 DE69307899T2 DE69307899T DE69307899T DE69307899T2 DE 69307899 T2 DE69307899 T2 DE 69307899T2 DE 69307899 T DE69307899 T DE 69307899T DE 69307899 T DE69307899 T DE 69307899T DE 69307899 T2 DE69307899 T2 DE 69307899T2
- Authority
- DE
- Germany
- Prior art keywords
- compound
- use according
- group
- formula
- radical
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
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Classifications
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/74—Synthetic polymeric materials
- A61K31/785—Polymers containing nitrogen
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/74—Synthetic polymeric materials
- A61K31/795—Polymers containing sulfur
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/74—Synthetic polymeric materials
- A61K31/80—Polymers containing hetero atoms not provided for in groups A61K31/755 - A61K31/795
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Treatments Of Macromolecular Shaped Articles (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Polyamides (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US93209692A | 1992-08-19 | 1992-08-19 | |
| PCT/US1993/006693 WO1994004164A1 (en) | 1992-08-19 | 1993-07-16 | Antiproliferative oligomers |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE69307899D1 DE69307899D1 (de) | 1997-03-13 |
| DE69307899T2 true DE69307899T2 (de) | 1997-06-26 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE69307899T Expired - Fee Related DE69307899T2 (de) | 1992-08-19 | 1993-07-16 | Antiproliferative oligomere |
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| US (1) | US5460807A (enExample) |
| EP (1) | EP0655922B1 (enExample) |
| JP (1) | JPH08502728A (enExample) |
| AT (1) | ATE148346T1 (enExample) |
| AU (1) | AU676184B2 (enExample) |
| CA (1) | CA2140865A1 (enExample) |
| DE (1) | DE69307899T2 (enExample) |
| DK (1) | DK0655922T3 (enExample) |
| ES (1) | ES2099962T3 (enExample) |
| GR (1) | GR3022937T3 (enExample) |
| HU (1) | HUT69286A (enExample) |
| IL (1) | IL106718A0 (enExample) |
| MX (1) | MX9305011A (enExample) |
| NO (1) | NO950601L (enExample) |
| NZ (1) | NZ254615A (enExample) |
| TW (1) | TW225514B (enExample) |
| WO (1) | WO1994004164A1 (enExample) |
| ZA (1) | ZA935940B (enExample) |
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| US5276182A (en) * | 1990-07-09 | 1994-01-04 | The Dow Chemical Company | Process for preparing polyurea oligomers |
| US6515009B1 (en) | 1991-09-27 | 2003-02-04 | Neorx Corporation | Therapeutic inhibitor of vascular smooth muscle cells |
| US5811447A (en) | 1993-01-28 | 1998-09-22 | Neorx Corporation | Therapeutic inhibitor of vascular smooth muscle cells |
| US5424063A (en) * | 1992-01-09 | 1995-06-13 | The Dow Chemical Company | Narrow poly- and mono-dispersed anionic oligomers, and their uses, formulations and process |
| US6251920B1 (en) | 1993-05-13 | 2001-06-26 | Neorx Corporation | Prevention and treatment of cardiovascular pathologies |
| US6395494B1 (en) | 1993-05-13 | 2002-05-28 | Neorx Corporation | Method to determine TGF-β |
| US6306421B1 (en) | 1992-09-25 | 2001-10-23 | Neorx Corporation | Therapeutic inhibitor of vascular smooth muscle cells |
| US5981568A (en) | 1993-01-28 | 1999-11-09 | Neorx Corporation | Therapeutic inhibitor of vascular smooth muscle cells |
| US6663881B2 (en) | 1993-01-28 | 2003-12-16 | Neorx Corporation | Therapeutic inhibitor of vascular smooth muscle cells |
| US6491938B2 (en) | 1993-05-13 | 2002-12-10 | Neorx Corporation | Therapeutic inhibitor of vascular smooth muscle cells |
| US5595722A (en) | 1993-01-28 | 1997-01-21 | Neorx Corporation | Method for identifying an agent which increases TGF-beta levels |
| WO1994026303A1 (en) * | 1993-05-13 | 1994-11-24 | Neorx Corporation | Prevention and treatment of pathologies associated with abnormally proliferative smooth muscle cells |
| US7611533B2 (en) | 1995-06-07 | 2009-11-03 | Cook Incorporated | Coated implantable medical device |
| AUPO104496A0 (en) * | 1996-07-17 | 1996-08-08 | Biomolecular Research Institute Limited | Angiogenic inhibitory compounds |
| US7087648B1 (en) * | 1997-10-27 | 2006-08-08 | The Regents Of The University Of California | Methods for modulating macrophage proliferation using polyamine analogs |
| US8198334B2 (en) * | 1997-10-27 | 2012-06-12 | Pathologica Llc | Methods for modulating macrophage proliferation in ocular disease using polyamine analogs |
| US6613083B2 (en) | 2001-05-02 | 2003-09-02 | Eckhard Alt | Stent device and method |
| AU2005294514A1 (en) * | 2004-10-04 | 2006-04-20 | Cellgate, Inc. | Polyamine analogs as therapeutic agents for ocular diseases |
| US11344385B2 (en) | 2015-02-23 | 2022-05-31 | Align Technology, Inc. | Primer aligner stages for lag issue resolution in low-stage clear aligner treatments |
Family Cites Families (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2833744A (en) * | 1953-08-27 | 1958-05-06 | Ciba Pharm Prod Inc | Polyureas and process of preparing same |
| GB781479A (en) * | 1953-08-27 | 1957-08-21 | Ciba Ltd | New polyureas and process for making them |
| DE1067212B (de) * | 1956-06-04 | 1959-10-15 | Farbenfabriken Bayer Aktiengesellschaft, Leverkusen-Bayerwerk | Verfahren zur Herstellung von löslichen Polyharnstoffen |
| US3164571A (en) * | 1959-12-31 | 1965-01-05 | Union Carbide Corp | Polyureas from n-phenyl, phenylene biscarbamyl halide and a diamine |
| US3528949A (en) * | 1968-05-07 | 1970-09-15 | Atlas Chem Ind | Polymers from ureas and dihalides |
| US4312855A (en) * | 1970-11-16 | 1982-01-26 | Colgate-Palmolive Company | Compositions containing aminopolyureylene resin |
| DE2162963C3 (de) * | 1971-12-18 | 1979-02-01 | Hoechst Ag, 6000 Frankfurt | Verfahren zur Herstellung von 1,4-Diaminobenzol-2,5-disulfonsäure |
| US3993625A (en) * | 1973-05-28 | 1976-11-23 | Toray Industries, Inc. | Permselective polymeric membranes of organic polyamide or polyhydrazide |
| US3978024A (en) * | 1973-12-28 | 1976-08-31 | General Electric Company | Flame retardant polycarbonate composition |
| DE2516305A1 (de) * | 1975-04-15 | 1976-10-28 | Dynamit Nobel Ag | Wasserdispergierbare esterharze |
| US4756907A (en) * | 1978-10-17 | 1988-07-12 | Stolle Research & Development Corp. | Active/passive immunization of the internal female reproductive organs |
| US4471110A (en) * | 1982-08-02 | 1984-09-11 | E. I. Dupont De Nemours And Company | Polyamide of disulfonated diamine and permselective membrane thereof |
| DE3345902A1 (de) * | 1983-12-20 | 1985-08-29 | Cassella Ag, 6000 Frankfurt | In wasser loesliche polymischester, verfahren zu ihrer herstellung und ihre verwendung |
| US4863735A (en) * | 1985-02-19 | 1989-09-05 | Massachusetts Institute Of Technology | Biodegradable polymeric drug delivery system with adjuvant activity |
| US4824916A (en) * | 1985-03-15 | 1989-04-25 | The Dow Chemical Company | Water-insoluble, crosslinked, sulfonated aromatic polyamide |
| US4604404A (en) * | 1985-04-03 | 1986-08-05 | A. H. Robins Company, Inc. | Antiviral sulfonated naphthalene formaldehyde condensation polymers |
| US4895660A (en) * | 1986-07-14 | 1990-01-23 | The Dow Chemical Company | Water-soluble aromatic polyamides and polyureas |
| US4897260A (en) * | 1987-05-22 | 1990-01-30 | The Rockefeller University | Compositions that affect suppression of cutaneous delayed hypersensitivity and products including same |
| US5032679A (en) * | 1988-12-15 | 1991-07-16 | Glycomed, Inc. | Heparin fragments as inhibitors of smooth muscle cell proliferation |
| IL95353A (en) * | 1989-08-14 | 1995-01-24 | Rhone Poulenc Rorer Int | Pharmaceutical preparations containing aromatic polymers |
| US5276182A (en) * | 1990-07-09 | 1994-01-04 | The Dow Chemical Company | Process for preparing polyurea oligomers |
-
1993
- 1993-06-15 US US08/077,891 patent/US5460807A/en not_active Expired - Fee Related
- 1993-07-16 DE DE69307899T patent/DE69307899T2/de not_active Expired - Fee Related
- 1993-07-16 CA CA002140865A patent/CA2140865A1/en not_active Abandoned
- 1993-07-16 DK DK93917220.1T patent/DK0655922T3/da active
- 1993-07-16 AT AT93917220T patent/ATE148346T1/de not_active IP Right Cessation
- 1993-07-16 HU HU9500492A patent/HUT69286A/hu unknown
- 1993-07-16 WO PCT/US1993/006693 patent/WO1994004164A1/en not_active Ceased
- 1993-07-16 JP JP6506256A patent/JPH08502728A/ja active Pending
- 1993-07-16 NZ NZ254615A patent/NZ254615A/en unknown
- 1993-07-16 ES ES93917220T patent/ES2099962T3/es not_active Expired - Lifetime
- 1993-07-16 EP EP93917220A patent/EP0655922B1/en not_active Expired - Lifetime
- 1993-07-16 AU AU46806/93A patent/AU676184B2/en not_active Ceased
- 1993-08-12 ZA ZA935940A patent/ZA935940B/xx unknown
- 1993-08-14 TW TW082106538A patent/TW225514B/zh active
- 1993-08-17 IL IL106718A patent/IL106718A0/xx unknown
- 1993-08-18 MX MX9305011A patent/MX9305011A/es unknown
-
1995
- 1995-02-17 NO NO950601A patent/NO950601L/no unknown
-
1997
- 1997-03-26 GR GR970400624T patent/GR3022937T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| AU4680693A (en) | 1994-03-15 |
| TW225514B (enExample) | 1994-06-21 |
| WO1994004164A1 (en) | 1994-03-03 |
| NO950601D0 (no) | 1995-02-17 |
| ES2099962T3 (es) | 1997-06-01 |
| DK0655922T3 (da) | 1997-02-17 |
| IL106718A0 (en) | 1993-12-08 |
| DE69307899D1 (de) | 1997-03-13 |
| EP0655922B1 (en) | 1997-01-29 |
| US5460807A (en) | 1995-10-24 |
| AU676184B2 (en) | 1997-03-06 |
| ZA935940B (en) | 1994-02-07 |
| NO950601L (no) | 1995-02-17 |
| HUT69286A (en) | 1995-09-28 |
| ATE148346T1 (de) | 1997-02-15 |
| JPH08502728A (ja) | 1996-03-26 |
| CA2140865A1 (en) | 1994-03-03 |
| GR3022937T3 (en) | 1997-06-30 |
| MX9305011A (es) | 1994-03-31 |
| NZ254615A (en) | 1997-06-24 |
| HU9500492D0 (en) | 1995-04-28 |
| EP0655922A1 (en) | 1995-06-07 |
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| 8364 | No opposition during term of opposition | ||
| 8339 | Ceased/non-payment of the annual fee |