DE69300532D1 - Naphtylalkylamine, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Zusammensetzungen. - Google Patents
Naphtylalkylamine, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Zusammensetzungen.Info
- Publication number
- DE69300532D1 DE69300532D1 DE69300532T DE69300532T DE69300532D1 DE 69300532 D1 DE69300532 D1 DE 69300532D1 DE 69300532 T DE69300532 T DE 69300532T DE 69300532 T DE69300532 T DE 69300532T DE 69300532 D1 DE69300532 D1 DE 69300532D1
- Authority
- DE
- Germany
- Prior art keywords
- naphtylalkylamines
- processes
- preparation
- pharmaceutical compositions
- compositions containing
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/57—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of rings other than six-membered aromatic rings
- C07C233/63—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of rings other than six-membered aromatic rings having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C233/02—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having nitrogen atoms of carboxamide groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals
- C07C233/04—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having nitrogen atoms of carboxamide groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals with carbon atoms of carboxamide groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton
- C07C233/05—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having nitrogen atoms of carboxamide groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals with carbon atoms of carboxamide groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton having the nitrogen atoms of the carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/57—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of rings other than six-membered aromatic rings
- C07C233/58—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of rings other than six-membered aromatic rings having the nitrogen atoms of the carboxamide groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/57—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of rings other than six-membered aromatic rings
- C07C233/60—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of rings other than six-membered aromatic rings having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
- C07C275/04—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to acyclic carbon atoms
- C07C275/20—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to acyclic carbon atoms of an unsaturated carbon skeleton
- C07C275/24—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to acyclic carbon atoms of an unsaturated carbon skeleton containing six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/02—Systems containing only non-condensed rings with a three-membered ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/04—Systems containing only non-condensed rings with a four-membered ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/06—Systems containing only non-condensed rings with a five-membered ring
- C07C2601/08—Systems containing only non-condensed rings with a five-membered ring the ring being saturated
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/14—The ring being saturated
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/16—Systems containing only non-condensed rings with a six-membered ring the ring being unsaturated
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Immunology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Dermatology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Indole Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR9203700A FR2689124A1 (fr) | 1992-03-27 | 1992-03-27 | Nouvelles naphtylalkylamines, leur procédé de préparation et les compositions pharmaceutiques qui les contiennent. |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69300532D1 true DE69300532D1 (de) | 1995-11-02 |
DE69300532T2 DE69300532T2 (de) | 1996-05-15 |
Family
ID=9428140
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69300532T Expired - Fee Related DE69300532T2 (de) | 1992-03-27 | 1993-03-24 | Naphtylalkylamine, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Zusammensetzungen. |
Country Status (13)
Country | Link |
---|---|
US (2) | US5420158A (de) |
EP (1) | EP0562956B1 (de) |
JP (1) | JPH0749404B2 (de) |
AT (1) | ATE128458T1 (de) |
AU (1) | AU657400B2 (de) |
CA (1) | CA2092794C (de) |
DE (1) | DE69300532T2 (de) |
DK (1) | DK0562956T3 (de) |
ES (1) | ES2081187T3 (de) |
FR (1) | FR2689124A1 (de) |
GR (1) | GR3018212T3 (de) |
NZ (1) | NZ247266A (de) |
ZA (1) | ZA932168B (de) |
Families Citing this family (36)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DK0528762T3 (da) * | 1991-08-15 | 1997-08-25 | Ciba Geigy Ag | N-acyl-N-heterocyclyl- eller naphthylalkyl-aminosyrer som angiotensin II antagonister |
US6048859A (en) * | 1992-06-29 | 2000-04-11 | Merck & Co., Inc. | Morpholine and thiomorpholine tachykinin receptor antagonists |
US5719147A (en) * | 1992-06-29 | 1998-02-17 | Merck & Co., Inc. | Morpholine and thiomorpholine tachykinin receptor antagonists |
FR2713636B1 (fr) * | 1993-12-07 | 1996-01-05 | Adir | Nouveaux dérivés naphtaléniques, leur procédé de préparation, et les compositions pharmaceutiques qui les contiennent. |
AU2109695A (en) | 1994-03-30 | 1995-10-23 | Novartis Ag | Screening method using the rzr receptor family |
US5849769A (en) * | 1994-08-24 | 1998-12-15 | Medivir Ab | N-arylalkyl-N-heteroarylurea and guandine compounds and methods of treating HIV infection |
ATE193700T1 (de) * | 1994-09-12 | 2000-06-15 | Takeda Chemical Industries Ltd | Benzozykloalkenverbindungen, deren herstellung und verwendung |
US5541228A (en) * | 1994-10-14 | 1996-07-30 | Bristol-Myers Squibb Co. | Melatonergic agents |
US5998461A (en) * | 1994-10-21 | 1999-12-07 | Adir Et Compagnie | Tricyclic amide compounds |
FR2725985B1 (fr) * | 1994-10-21 | 1996-11-15 | Adir | Nouveaux composes tricycliques, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
US6071946A (en) * | 1994-10-21 | 2000-06-06 | Adir Et Compagnie | Tricyclic urea compounds |
US5530012A (en) | 1994-12-22 | 1996-06-25 | Bristol-Myers Squibb Co. | 3-alkoxybenzylpiperidine derivatives as melatonergic agents |
FR2729147A1 (fr) * | 1995-01-11 | 1996-07-12 | Adir | Nouveaux composes (hetero) cycliques alkyles, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
US5661186A (en) * | 1995-02-24 | 1997-08-26 | Bristol-Myers Squibb Co. | Tetralinyl-and indanyl-ethylamides |
AUPO274596A0 (en) * | 1996-10-04 | 1996-10-31 | Armstrong, Stuart Maxwell | Method for the treatment of neurological or neuropsychiatric disorders |
US6310085B1 (en) | 1997-10-03 | 2001-10-30 | Clarencew Pty Ltd. | Method for the treatment of neurological or neuropsychiatric disorders |
PT1027043E (pt) * | 1996-12-10 | 2005-02-28 | Bristol Myers Squibb Co | Benzodioxole benzofurano di-hidrobenzofurano e benzodioxano como agentes melatonergicos |
US6028112A (en) * | 1997-05-23 | 2000-02-22 | Bristol-Myers Squibb Company | Spirocyclopropyl fluorenes as melatonergic agents |
FR2778662B1 (fr) | 1998-05-12 | 2000-06-16 | Adir | Nouveaux composes cycliques substitues, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
US6214869B1 (en) | 1998-06-05 | 2001-04-10 | Bristol-Myers Squibb | Heterocyclic cis cyclopropane derivatives as melatonergic agents |
US6617351B1 (en) * | 1998-07-31 | 2003-09-09 | Eli Lilly And Company | Amide, carbamate, and urea derivatives |
PE20000942A1 (es) * | 1998-07-31 | 2000-09-28 | Lilly Co Eli | Derivados de amida, carbamato y urea |
FR2793793B1 (fr) * | 1999-05-19 | 2004-02-27 | Adir | Nouveaux derives dimeriques substitues, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
EP1189900B1 (de) | 1999-06-30 | 2004-01-14 | Bristol-Myers Squibb Company | Heterocyclische aminopyrrolidon-derivate als melatonergene wirkstoffe |
US6952041B2 (en) | 2003-07-25 | 2005-10-04 | Robert Bosch Gmbh | Anchors for microelectromechanical systems having an SOI substrate, and method of fabricating same |
FR2903102B1 (fr) * | 2006-06-30 | 2010-08-13 | Servier Lab | Nouveaux derives naphtaleniques, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
FR2903103B1 (fr) * | 2006-06-30 | 2010-08-13 | Servier Lab | Nouveaux derives naphtaleniques, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
FR2903101B1 (fr) * | 2006-06-30 | 2008-09-26 | Servier Lab | Nouveaux derives naphtaleniques, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
AU2008247805A1 (en) * | 2007-05-01 | 2008-11-13 | Concert Pharmaceuticals Inc. | Naphthyl(ethyl) acetamides |
FR2918372B1 (fr) * | 2007-07-02 | 2009-08-28 | Servier Lab | Nouveaux derives naphtaleniques,leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
FR2918370B1 (fr) * | 2007-07-02 | 2009-08-28 | Servier Lab | Nouveaux derives naphtaleniques,leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
BR112014032834A8 (pt) | 2012-06-29 | 2021-03-16 | Johnson & Johnson Vision Care | dispositivo oftálmico eletroativo de múltiplos estados |
WO2014064706A1 (en) * | 2012-10-22 | 2014-05-01 | Symed Labs Limited | Processes for the preparation of agomelatine using novel intermediates |
WO2016046833A2 (en) * | 2014-09-24 | 2016-03-31 | Symed Labs Limited | Improved processes for the preparation of agomelatine using novel intermediates |
CN107325011A (zh) * | 2016-04-30 | 2017-11-07 | 陕西合成药业股份有限公司 | 一种褪黑激素类化合物及其制备方法和用途 |
TW202214558A (zh) * | 2020-07-28 | 2022-04-16 | 大陸商上海翰森生物醫藥科技有限公司 | 雙環類衍生物調節劑、其製備方法和應用 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4916223A (en) * | 1986-08-28 | 1990-04-10 | Merck & Co., Inc. | Substituted hexahydroarylquinolizines |
DE68911203T2 (de) * | 1988-03-30 | 1994-04-14 | Warner Lambert Co | N-[[(2,6-disubstituierte)phenyl]N'- arylalkyl] Harnstoffe als antihypercholesterolemische und antiatherosclerotische Mittel. |
DE3828566A1 (de) * | 1988-08-23 | 1990-03-15 | Thomae Gmbh Dr K | Neue benzolsulfonamido-verbindungen, diese verbindungen enthaltende arzneimittel und verfahren zu ihrer herstellung |
FR2658818B1 (fr) * | 1990-02-27 | 1993-12-31 | Adir Cie | Nouveaux derives a structure naphtalenique, leur procede de preparation et les compositions pharmaceutiques qui les contiennent. |
-
1992
- 1992-03-27 FR FR9203700A patent/FR2689124A1/fr not_active Withdrawn
-
1993
- 1993-03-23 US US08/035,936 patent/US5420158A/en not_active Expired - Fee Related
- 1993-03-24 DE DE69300532T patent/DE69300532T2/de not_active Expired - Fee Related
- 1993-03-24 EP EP93400757A patent/EP0562956B1/de not_active Expired - Lifetime
- 1993-03-24 ES ES93400757T patent/ES2081187T3/es not_active Expired - Lifetime
- 1993-03-24 DK DK93400757.6T patent/DK0562956T3/da active
- 1993-03-24 AT AT93400757T patent/ATE128458T1/de not_active IP Right Cessation
- 1993-03-26 NZ NZ247266A patent/NZ247266A/en unknown
- 1993-03-26 CA CA002092794A patent/CA2092794C/fr not_active Expired - Fee Related
- 1993-03-26 AU AU35445/93A patent/AU657400B2/en not_active Ceased
- 1993-03-26 JP JP5105844A patent/JPH0749404B2/ja not_active Expired - Fee Related
- 1993-03-26 ZA ZA932168A patent/ZA932168B/xx unknown
-
1995
- 1995-01-25 US US08/377,812 patent/US5616614A/en not_active Expired - Fee Related
- 1995-11-27 GR GR950403327T patent/GR3018212T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
GR3018212T3 (en) | 1996-02-29 |
ES2081187T3 (es) | 1996-02-16 |
DK0562956T3 (da) | 1996-02-05 |
CA2092794C (fr) | 1999-03-23 |
AU3544593A (en) | 1993-09-30 |
ZA932168B (en) | 1993-11-08 |
EP0562956A1 (de) | 1993-09-29 |
US5420158A (en) | 1995-05-30 |
US5616614A (en) | 1997-04-01 |
FR2689124A1 (fr) | 1993-10-01 |
ATE128458T1 (de) | 1995-10-15 |
EP0562956B1 (de) | 1995-09-27 |
NZ247266A (en) | 1995-09-26 |
DE69300532T2 (de) | 1996-05-15 |
JPH0649011A (ja) | 1994-02-22 |
CA2092794A1 (fr) | 1993-09-28 |
AU657400B2 (en) | 1995-03-09 |
JPH0749404B2 (ja) | 1995-05-31 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8327 | Change in the person/name/address of the patent owner |
Owner name: LES LABORATOIRES SERVIER, NEUILLY SUR SEINE, FR |
|
8339 | Ceased/non-payment of the annual fee |