GB9022543D0
(en)
*
|
1990-10-17 |
1990-11-28 |
Wellcome Found |
Antibody production
|
GB9125768D0
(en)
*
|
1991-12-04 |
1992-02-05 |
Hale Geoffrey |
Therapeutic method
|
GB9603507D0
(en)
|
1996-02-20 |
1996-04-17 |
Isis Innovation |
Antibody variants
|
US7541184B2
(en)
|
2000-02-24 |
2009-06-02 |
Invitrogen Corporation |
Activation and expansion of cells
|
US7572631B2
(en)
|
2000-02-24 |
2009-08-11 |
Invitrogen Corporation |
Activation and expansion of T cells
|
US20060057107A1
(en)
*
|
2001-12-21 |
2006-03-16 |
Shaked Ze Ev |
Combination treatment for multiple sclerosis
|
JP2005517025A
(ja)
*
|
2002-02-08 |
2005-06-09 |
エクサイト セラピーズ, インコーポレイテッド |
免疫学的欠損を有する患者において免疫応答性を回復するための、組成物および方法
|
EP1539929B1
(de)
|
2002-06-28 |
2013-04-10 |
Life Technologies Corporation |
Verfahren zur wiederherstellung des immunrepertoirs in patienten mit immunologischen defekten in verbindung mit autoimmunität sowie transplantation von organen oder hämatopoetischen stammzellen
|
MXPA05012080A
(es)
*
|
2003-05-08 |
2006-02-22 |
Xcyte Therapies Inc |
Generacion y aislamiento de celulas t especificas al antigeno.
|
CA2539716A1
(en)
*
|
2003-09-22 |
2005-04-07 |
Xcyte Therapies, Inc. |
Compositions and methods to accelerate hematologic recovery
|
EP1694706B1
(de)
|
2003-11-01 |
2012-04-04 |
Merck Patent GmbH |
Modifizierter anti-cd52-antikörper
|
CA2649296A1
(en)
|
2006-04-13 |
2007-10-25 |
Peptimmune, Inc. |
Methods for designing and synthesizing directed sequence polymer compositions via the directed expansion of epitope permeability
|
EP1854810A1
(de)
|
2006-05-09 |
2007-11-14 |
PanGenetics B.V. |
De-immunisierter und antagonister monoclonaler Antikörper gegen CD40, der aus der ch5D12 Antikörper abgeleitet ist
|
US9498528B2
(en)
*
|
2006-09-13 |
2016-11-22 |
Genzyme Corporation |
Treatment of multiple sclerosis (MS)
|
ES2917882T3
(es)
*
|
2006-09-13 |
2022-07-12 |
Alcafleu Man Gmbh & Co Kg |
Tratamiento de esclerosis múltiple (MS) con Campath-1H
|
LT2130044T
(lt)
|
2007-02-16 |
2017-02-10 |
Genzyme Corporation |
Skydliaukės sutrikimo rizikos nustatymo būdas
|
EP3456733A1
(de)
*
|
2007-05-11 |
2019-03-20 |
Genzyme Corporation |
Verfahren zur herstellung eines sekretierten proteins
|
TWI614267B
(zh)
*
|
2009-05-13 |
2018-02-11 |
建新公司 |
抗人類cd52免疫球蛋白
|
BRPI1013927A2
(pt)
|
2009-05-13 |
2016-04-05 |
Genzyme Corp |
métodos e composições para o tratamento de lúpus
|
PT3214091T
(pt)
|
2010-12-09 |
2019-01-11 |
Univ Pennsylvania |
Utilização de células t modificadas por recetor de antigénio quimérico para tratar o cancro
|
KR20140004174A
(ko)
|
2011-01-18 |
2014-01-10 |
더 트러스티스 오브 더 유니버시티 오브 펜실바니아 |
암 치료를 위한 조성물 및 방법
|
WO2013019615A2
(en)
|
2011-07-29 |
2013-02-07 |
The Trustees Of The University Of Pennsylvania |
Switch costimulatory receptors
|
EP2756521A4
(de)
|
2011-09-16 |
2015-04-22 |
Univ Pennsylvania |
Rna-manipulierte t-zellen zur behandlung von krebs
|
US9272002B2
(en)
|
2011-10-28 |
2016-03-01 |
The Trustees Of The University Of Pennsylvania |
Fully human, anti-mesothelin specific chimeric immune receptor for redirected mesothelin-expressing cell targeting
|
EP2773651B1
(de)
|
2011-11-03 |
2020-12-23 |
The Trustees of the University of Pennsylvania |
Isolierte b7-h4-spezifische zusammensetzungen und anwendungsverfahren dafür
|
WO2013070468A1
(en)
|
2011-11-08 |
2013-05-16 |
The Trustees Of The University Of Pennsylvania |
Glypican-3-specific antibody and uses thereof
|
CA2864688C
(en)
|
2012-02-22 |
2023-09-05 |
The Trustees Of The University Of Pennsylvania |
Use of icos-based cars to enhance antitumor activity and car persistence
|
CA2864489C
(en)
|
2012-02-22 |
2023-08-08 |
The Trustees Of The University Of Pennsylvania |
Use of the cd2 signaling domain in second-generation chimeric antigen receptors
|
WO2014011988A2
(en)
|
2012-07-13 |
2014-01-16 |
The Trustees Of The University Of Pennsylvania |
Enhancing activity of car t cells by co-introducing a bispecific antibody
|
EP3584256A1
(de)
|
2012-07-13 |
2019-12-25 |
The Trustees Of The University Of Pennsylvania |
Verfahren zur beurteilung der eignung von transduzierten t-zellen zur verabreichung
|
CN104427997B
(zh)
|
2012-07-13 |
2020-12-11 |
宾夕法尼亚大学董事会 |
对cars的抗肿瘤活性的毒性管理
|
WO2014055771A1
(en)
|
2012-10-05 |
2014-04-10 |
The Trustees Of The University Of Pennsylvania |
Human alpha-folate receptor chimeric antigen receptor
|
CN105518018B
(zh)
*
|
2013-03-15 |
2020-04-03 |
细胞基因公司 |
修饰的t淋巴细胞
|
US9446105B2
(en)
|
2013-03-15 |
2016-09-20 |
The Trustees Of The University Of Pennsylvania |
Chimeric antigen receptor specific for folate receptor β
|
AR095199A1
(es)
|
2013-03-15 |
2015-09-30 |
Genzyme Corp |
Anticuerpos anti-cd52
|
TWI654206B
(zh)
|
2013-03-16 |
2019-03-21 |
諾華公司 |
使用人類化抗-cd19嵌合抗原受體治療癌症
|
EP3083964B1
(de)
|
2013-12-19 |
2022-01-26 |
Novartis AG |
Menschliche chimäre mesothelin-antigenrezeptoren und verwendungen davon
|
ES2963718T3
(es)
|
2014-01-21 |
2024-04-01 |
Novartis Ag |
Capacidad presentadora de antígenos de células CAR-T potenciada mediante introducción conjunta de moléculas co-estimuladoras
|
ES2939760T3
(es)
|
2014-03-15 |
2023-04-26 |
Novartis Ag |
Tratamiento de cáncer utilizando un receptor quimérico para antígenos
|
KR102487608B1
(ko)
|
2014-04-07 |
2023-01-12 |
노파르티스 아게 |
항-cd19 키메라 항원 수용체를 사용한 암의 치료
|
WO2015168613A2
(en)
|
2014-05-02 |
2015-11-05 |
The Trustees Of The University Of Pennsylvania |
Compositions and methods of chimeric autoantibody receptor t cells
|
TWI719942B
(zh)
|
2014-07-21 |
2021-03-01 |
瑞士商諾華公司 |
使用cd33嵌合抗原受體治療癌症
|
WO2016014553A1
(en)
|
2014-07-21 |
2016-01-28 |
Novartis Ag |
Sortase synthesized chimeric antigen receptors
|
EP3660042B1
(de)
|
2014-07-31 |
2023-01-11 |
Novartis AG |
T-zellen mit teilmengenoptimierten chimären antigenrezeptoren
|
WO2016025880A1
(en)
|
2014-08-14 |
2016-02-18 |
Novartis Ag |
Treatment of cancer using gfr alpha-4 chimeric antigen receptor
|
EP3204777A1
(de)
|
2014-10-08 |
2017-08-16 |
Novartis AG |
Prädiktive biomarker für das therapeutische ansprechen auf chimäre antigenrezeptortherapie und verwendung davon
|
ES2910227T3
(es)
|
2014-10-31 |
2022-05-12 |
Univ Pennsylvania |
Composición y métodos para la estimulación y expansión de células T
|
EP4219725A3
(de)
|
2014-10-31 |
2023-08-30 |
The Trustees of the University of Pennsylvania |
Änderung der genexpression in modifizierten t-zellen und verwendungen davon
|
WO2016090034A2
(en)
|
2014-12-03 |
2016-06-09 |
Novartis Ag |
Methods for b cell preconditioning in car therapy
|
JP7170394B2
(ja)
|
2015-01-31 |
2022-11-14 |
ザ トラスティーズ オブ ザ ユニバーシティ オブ ペンシルバニア |
治療用分子のt細胞送達のための組成物および方法
|
WO2016126608A1
(en)
|
2015-02-02 |
2016-08-11 |
Novartis Ag |
Car-expressing cells against multiple tumor antigens and uses thereof
|
EP3259284B1
(de)
|
2015-02-16 |
2020-04-01 |
The Trustees of the University of Pennsylvania |
Vollhumaner t-zellrezeptor spezifisch für das 369 377-epitop aus dem her2/neu (erbb2)-rezeptorprotein
|
BR112017018770A2
(pt)
|
2015-03-02 |
2018-04-17 |
Innovative Cellular Therapeutics CO., LTD. |
redução da tolerância imunológica induzida por pd-l1
|
EP3280795B1
(de)
|
2015-04-07 |
2021-03-24 |
Novartis AG |
Kombination von chimärer antigen rezeptor therapie und amino pyrimidin derivaten
|
ES2948133T3
(es)
|
2015-04-17 |
2023-08-31 |
Novartis Ag |
Métodos para mejorar la eficacia y expansión de células que expresan un receptor de antígeno quimérico
|
US20180298068A1
(en)
|
2015-04-23 |
2018-10-18 |
Novartis Ag |
Treatment of cancer using chimeric antigen receptor and protein kinase a blocker
|
CA2986254A1
(en)
|
2015-05-18 |
2016-11-24 |
TCR2 Therapeutics Inc. |
Compositions and methods for tcr reprogramming using fusion proteins
|
KR101997241B1
(ko)
|
2015-05-21 |
2019-07-09 |
하푼 테라퓨틱스, 인크. |
삼중특이성 결합 단백질 및 사용 방법
|
WO2018126369A1
(en)
|
2017-01-05 |
2018-07-12 |
Shanghai Sidansai Biotechnology Co., Ltd |
Humanized anti-cd19 antibody and use thereof with chimeric antigen receptor
|
US11649435B2
(en)
|
2015-08-28 |
2023-05-16 |
The Trustees Of The University Of Pennsylvania |
Methods and compositions for cells expressing a chimeric intracellular signaling molecule
|
EP3340995A4
(de)
|
2015-08-28 |
2019-04-03 |
The Trustees Of The University Of Pennsylvania |
Verfahren und zusammensetzungen für zellen zur expression eines chimären intrazellulären signalmoleküls
|
US11747346B2
(en)
|
2015-09-03 |
2023-09-05 |
Novartis Ag |
Biomarkers predictive of cytokine release syndrome
|
EP3359650A4
(de)
|
2015-10-08 |
2019-03-20 |
Innovative Cellular Therapeutics Co., Ltd. |
Aktivierung und expansion von zellen
|
JP7118887B2
(ja)
|
2015-11-23 |
2022-08-16 |
ノバルティス アーゲー |
最適化されたレンチウイルス移入ベクターおよびその使用
|
MA44140A
(fr)
|
2015-12-22 |
2021-05-19 |
Dana Farber Cancer Inst Inc |
Récepteur d'antigène chimérique (car) contre la mésothéline et anticorps contre l'inhibiteur de pd-l1 pour une utilisation combinée dans une thérapie anticancéreuse
|
SG11201807489PA
(en)
|
2016-03-04 |
2018-09-27 |
Novartis Ag |
Cells expressing multiple chimeric antigen receptor (car) molecules and uses therefore
|
EP3432924A1
(de)
|
2016-03-23 |
2019-01-30 |
Novartis AG |
Zellsekretierte minikörper und verwendungen davon
|
CN113082201A
(zh)
|
2016-04-01 |
2021-07-09 |
上海斯丹赛生物技术有限公司 |
刺激t细胞介导的对表达抗原的细胞群的免疫应答的方法
|
RU2018140056A
(ru)
|
2016-04-15 |
2020-05-15 |
Дзе Трастиз Оф Дзе Юниверсити Оф Пенсильвания |
Композиции и способы с использованием т-клеток с химерным рецептором аллоантигена
|
BR112018073739A2
(pt)
|
2016-05-20 |
2019-02-26 |
Harpoon Therapeutics, Inc. |
proteína de ligação de albumina sérica de domínio único
|
US11623958B2
(en)
|
2016-05-20 |
2023-04-11 |
Harpoon Therapeutics, Inc. |
Single chain variable fragment CD3 binding proteins
|
EP3485017A4
(de)
|
2016-07-18 |
2020-03-04 |
Helix Biopharma Corp. |
Gegen das mit dem karzinoembryonischen antigen in verbindung stehende zelladhäsionsmolekül 6 gerichtete car-immunzellen zur behandlung von krebs
|
JP7109789B2
(ja)
|
2016-08-02 |
2022-08-01 |
ティーシーアール2 セラピューティクス インク. |
融合タンパク質を使用したtcrの再プログラム化のための組成物及び方法
|
MX2019003899A
(es)
|
2016-10-07 |
2019-08-14 |
Tcr2 Therapeutics Inc |
Composiciones y metodos para reprogramacion de receptores de linfocitos t mediante el uso de proteinas de fusion.
|
EP3523331A1
(de)
|
2016-10-07 |
2019-08-14 |
Novartis AG |
Chimäre antigenrezeptoren zur behandlung von krebs
|
GB2605540B
(en)
|
2016-10-18 |
2022-12-21 |
Univ Minnesota |
Tumor infiltrating lymphocytes and methods of therapy
|
CN110177803A
(zh)
|
2016-11-22 |
2019-08-27 |
T细胞受体治疗公司 |
用于使用融合蛋白进行tcr重新编程的组合物和方法
|
KR102275008B1
(ko)
|
2016-11-23 |
2021-07-13 |
하푼 테라퓨틱스, 인크. |
전립선 특이 막 항원 결합 단백질
|
MX2019006045A
(es)
|
2016-11-23 |
2019-11-11 |
Harpoon Therapeutics Inc |
Proteinas triespecificas dirigidas a psma y metodos de uso.
|
WO2018111340A1
(en)
|
2016-12-16 |
2018-06-21 |
Novartis Ag |
Methods for determining potency and proliferative function of chimeric antigen receptor (car)-t cells
|
EP3558348A1
(de)
|
2016-12-21 |
2019-10-30 |
TCR2 Therapeutics Inc. |
Manipulierte t-zellen zur behandlung von krebs
|
EP3589662A4
(de)
|
2017-02-28 |
2020-12-30 |
Harpoon Therapeutics, Inc. |
Induzierbares monovalentes antigenbindendes protein
|
US20200055948A1
(en)
|
2017-04-28 |
2020-02-20 |
Novartis Ag |
Cells expressing a bcma-targeting chimeric antigen receptor, and combination therapy with a gamma secretase inhibitor
|
US10543271B2
(en)
|
2017-05-12 |
2020-01-28 |
Harpoon Therapeutics, Inc. |
Mesothelin binding proteins
|
EP3621648A4
(de)
|
2017-05-12 |
2021-01-20 |
Harpoon Therapeutics, Inc. |
Auf trispezifische proteine abzielendes msln und verfahren zur verwendung
|
EP3638295A1
(de)
|
2017-06-13 |
2020-04-22 |
TCR2 Therapeutics Inc. |
Zusammensetzungen und verfahren zur tcr-reprogrammierung mithilfe von fusionsproteinen
|
AU2018346719A1
(en)
|
2017-10-06 |
2020-04-23 |
Oslo Universitetssykehus Hf |
Chimeric antigen receptors
|
US11136403B2
(en)
|
2017-10-13 |
2021-10-05 |
Harpoon Therapeutics, Inc. |
Trispecific proteins and methods of use
|
EP3694871A4
(de)
|
2017-10-13 |
2021-11-10 |
Harpoon Therapeutics, Inc. |
B-zellreifungs-antigenbindende proteine
|
JP2021502979A
(ja)
|
2017-11-15 |
2021-02-04 |
ノバルティス アーゲー |
Bcmaターゲティングキメラ抗原受容体、cd19ターゲティングキメラ抗原受容体及び併用療法
|
EP3684399A1
(de)
|
2017-12-29 |
2020-07-29 |
Cellectis |
Verfahren zur verbesserung der produktion von car-t-zellen
|
WO2019136432A1
(en)
|
2018-01-08 |
2019-07-11 |
Novartis Ag |
Immune-enhancing rnas for combination with chimeric antigen receptor therapy
|
AU2019215031A1
(en)
|
2018-01-31 |
2020-08-20 |
Novartis Ag |
Combination therapy using a chimeric antigen receptor
|
EP3752203A1
(de)
|
2018-02-13 |
2020-12-23 |
Novartis AG |
Chimäre antigenrezeptortherapie in kombination mit il-15r und il15
|
EP3788369A1
(de)
|
2018-05-01 |
2021-03-10 |
Novartis Ag |
Biomarker zur auswertung von car-t-zellen zur vorhersage des klinischen ergebnisses
|
CA3101028A1
(en)
|
2018-06-05 |
2019-12-12 |
The Trustees Of The University Of Pennsylvania |
Compositions and methods of muscle specific kinase chimeric autoantibody receptor cells
|
CA3100724A1
(en)
|
2018-06-13 |
2019-12-19 |
Novartis Ag |
B-cell maturation antigen protein (bcma) chimeric antigen receptors and uses thereof
|
WO2019241549A1
(en)
|
2018-06-15 |
2019-12-19 |
A2 Biotherapeutics, Inc. |
Foxp3-expressing car-t regulatory cells
|
DE202019005887U1
(de)
|
2018-07-03 |
2023-06-14 |
Marengo Therapeutics, Inc. |
Anti-TCR-Antikörpermoleküle und Verwendungen davon
|
WO2020036875A1
(en)
|
2018-08-13 |
2020-02-20 |
Rootpath Genomics, Inc. |
High throughput cloning of paired bipartite immunoreceptor polynucleotides and applications thereof
|
CN113039209A
(zh)
|
2018-08-30 |
2021-06-25 |
T细胞受体治疗公司 |
用于使用融合蛋白进行tcr重编程的组合物和方法
|
JP7425049B2
(ja)
|
2018-09-25 |
2024-01-30 |
ハープーン セラピューティクス,インク. |
Dll3結合タンパク質および使用方法
|
EP3856779A1
(de)
|
2018-09-28 |
2021-08-04 |
Novartis AG |
Chimäre cd22-antigen-rezeptor(car)-therapien
|
US20210347851A1
(en)
|
2018-09-28 |
2021-11-11 |
Novartis Ag |
Cd19 chimeric antigen receptor (car) and cd22 car combination therapies
|
WO2020092455A2
(en)
|
2018-10-29 |
2020-05-07 |
The Broad Institute, Inc. |
Car t cell transcriptional atlas
|
JP7379654B2
(ja)
|
2019-03-15 |
2023-11-14 |
カーティザン セラピューティクス,インコーポレーテッド |
抗bcmaキメラ抗原受容体
|
AU2020253491A1
(en)
|
2019-04-05 |
2021-10-28 |
Rootpath Genomics, Inc. |
Compositions and methods for T-cell receptor gene assembly
|
WO2021035170A1
(en)
|
2019-08-21 |
2021-02-25 |
Precision Biosciences, Inc. |
Compositions and methods for tcr reprogramming using fusion proteins
|
CA3162892A1
(en)
|
2019-11-26 |
2021-06-03 |
Novartis Ag |
Cd19 and cd22 chimeric antigen receptors and uses thereof
|
EP4106806A1
(de)
|
2020-02-21 |
2022-12-28 |
Harpoon Therapeutics, Inc. |
Flt3-bindende proteine und verfahren zur verwendung
|
IL298473A
(en)
|
2020-06-11 |
2023-01-01 |
Novartis Ag |
zbtb32 inhibitors and uses thereof
|
MX2023005609A
(es)
|
2020-11-13 |
2023-05-29 |
Novartis Ag |
Terapias de combinacion con celulas que expresan receptores quimericos para el antigeno (car).
|
WO2022254337A1
(en)
|
2021-06-01 |
2022-12-08 |
Novartis Ag |
Cd19 and cd22 chimeric antigen receptors and uses thereof
|