ATE442157T1 - Verwendung von anti-cd3 monoklonale antikírper und il-5 zur behandlung von autoimmunkrankheiten - Google Patents
Verwendung von anti-cd3 monoklonale antikírper und il-5 zur behandlung von autoimmunkrankheitenInfo
- Publication number
- ATE442157T1 ATE442157T1 AT00977328T AT00977328T ATE442157T1 AT E442157 T1 ATE442157 T1 AT E442157T1 AT 00977328 T AT00977328 T AT 00977328T AT 00977328 T AT00977328 T AT 00977328T AT E442157 T1 ATE442157 T1 AT E442157T1
- Authority
- AT
- Austria
- Prior art keywords
- treatment
- monoclonal antibodies
- autoimmune diseases
- inhibiting
- immune response
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
- C07K16/2809—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against the T-cell receptor (TcR)-CD3 complex
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/20—Interleukins [IL]
- A61K38/2033—IL-5
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/39541—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against normal tissues, cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/57—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
Landscapes
- Health & Medical Sciences (AREA)
- Immunology (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Epidemiology (AREA)
- Mycology (AREA)
- Biomedical Technology (AREA)
- Microbiology (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Biochemistry (AREA)
- Transplantation (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Audible-Bandwidth Dynamoelectric Transducers Other Than Pickups (AREA)
- Steroid Compounds (AREA)
- Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AUPQ4312A AUPQ431299A0 (en) | 1999-11-26 | 1999-11-26 | Method of inducing immune tolerance |
PCT/AU2000/001441 WO2001037860A1 (en) | 1999-11-26 | 2000-11-24 | Method of inducing immune tolerance |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE442157T1 true ATE442157T1 (de) | 2009-09-15 |
Family
ID=3818454
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT00977328T ATE442157T1 (de) | 1999-11-26 | 2000-11-24 | Verwendung von anti-cd3 monoklonale antikírper und il-5 zur behandlung von autoimmunkrankheiten |
Country Status (7)
Country | Link |
---|---|
US (1) | US7744863B1 (de) |
EP (1) | EP1379270B1 (de) |
AT (1) | ATE442157T1 (de) |
AU (2) | AUPQ431299A0 (de) |
CA (1) | CA2429394A1 (de) |
DE (1) | DE60042941D1 (de) |
WO (1) | WO2001037860A1 (de) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB2380127A (en) * | 2001-09-26 | 2003-04-02 | Isis Innovation | Treatment of chronic joint inflammation |
US7695723B2 (en) * | 2002-12-31 | 2010-04-13 | Sygnis Bioscience Gmbh & Co. Kg | Methods of treating neurological conditions with hematopoietic growth factors |
EP2397189B1 (de) * | 2003-11-14 | 2015-03-18 | Brigham and Women's Hospital, Inc. | Verfahren zur Modulierung von Immunität |
SI1755674T1 (sl) | 2004-05-14 | 2015-04-30 | Alexion Pharmaceuticals, Inc. | Podaljšanje preživetja alotransplantata z inhibiranjem aktivnosti komplementa |
EP1851308B1 (de) | 2005-02-02 | 2013-08-21 | NewSouth Innovations Pty Limited | Gegen ein spezifisches antigen aktivierte cd4+ cd25+ t-zellen |
MX2008011054A (es) | 2006-03-02 | 2009-03-03 | Alexion Pharma Inc | Prolongacion de supervivencia de un aloinjerto, mediante la inhibicion de actividad de complemento. |
WO2008014555A1 (en) | 2006-08-02 | 2008-02-07 | Newsouth Innovations Pty Limited | Method of identifying cd4+cd25+ t cells activated to an antigen which express cd8 |
WO2008063849A2 (en) * | 2006-11-03 | 2008-05-29 | Northwestern University | Multiple sclerosis therapy |
BR112012027531A2 (pt) * | 2010-04-29 | 2017-08-08 | Hadasit Medical Res Service And Development Co Ltd | método de tratamento e/ou prevenção de progresso e/ou atraso de desenvolvimento de hepatite em um indivíduo, uso de uma molécula imunológica anti-cd3 e composição farmacêutica |
US9447187B2 (en) | 2011-02-03 | 2016-09-20 | Alexion Pharmaceuticals, Inc. | Use of an anti-CD200 antibody for prolonging the survival of allografts |
WO2015023972A1 (en) | 2013-08-16 | 2015-02-19 | Alexion Pharmaceuticals, Inc. | Treatment of graft rejection by administering a complement inhibitor to an organ prior to transplant |
WO2020232247A1 (en) | 2019-05-14 | 2020-11-19 | Provention Bio, Inc. | Methods and compositions for preventing type 1 diabetes |
BR112022025381A2 (pt) | 2020-06-11 | 2023-01-24 | Provention Bio Inc | Métodos e composições para prevenir diabetes tipo 1 |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5885573A (en) * | 1993-06-01 | 1999-03-23 | Arch Development Corporation | Methods and materials for modulation of the immunosuppressive activity and toxicity of monoclonal antibodies |
AU7467898A (en) * | 1997-04-21 | 1998-11-13 | Arch Development Corporation | Fc receptor non-binding anti-cd3 monoclonal antibodies deliver a partial cr signal and induce clonal anergy |
-
1999
- 1999-11-26 AU AUPQ4312A patent/AUPQ431299A0/en not_active Abandoned
-
2000
- 2000-11-24 US US10/148,010 patent/US7744863B1/en not_active Expired - Fee Related
- 2000-11-24 EP EP00977328A patent/EP1379270B1/de not_active Expired - Lifetime
- 2000-11-24 CA CA002429394A patent/CA2429394A1/en not_active Abandoned
- 2000-11-24 WO PCT/AU2000/001441 patent/WO2001037860A1/en active Application Filing
- 2000-11-24 DE DE60042941T patent/DE60042941D1/de not_active Expired - Lifetime
- 2000-11-24 AU AU15065/01A patent/AU1506501A/en not_active Withdrawn
- 2000-11-24 AT AT00977328T patent/ATE442157T1/de not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
EP1379270A4 (de) | 2004-01-14 |
US7744863B1 (en) | 2010-06-29 |
EP1379270B1 (de) | 2009-09-09 |
AUPQ431299A0 (en) | 1999-12-23 |
EP1379270A1 (de) | 2004-01-14 |
CA2429394A1 (en) | 2001-05-31 |
WO2001037860A1 (en) | 2001-05-31 |
DE60042941D1 (de) | 2009-10-22 |
AU1506501A (en) | 2001-06-04 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |