DE69228162T2 - Netzverband und Verfahren zu seiner Herstellung - Google Patents
Netzverband und Verfahren zu seiner HerstellungInfo
- Publication number
- DE69228162T2 DE69228162T2 DE69228162T DE69228162T DE69228162T2 DE 69228162 T2 DE69228162 T2 DE 69228162T2 DE 69228162 T DE69228162 T DE 69228162T DE 69228162 T DE69228162 T DE 69228162T DE 69228162 T2 DE69228162 T2 DE 69228162T2
- Authority
- DE
- Germany
- Prior art keywords
- dressing
- gel
- water
- humectant
- dressing according
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 238000000034 method Methods 0.000 title claims abstract description 10
- 238000004519 manufacturing process Methods 0.000 title description 8
- 230000008569 process Effects 0.000 title description 2
- 239000003906 humectant Substances 0.000 claims abstract description 19
- 229920000642 polymer Polymers 0.000 claims abstract description 7
- 239000000243 solution Substances 0.000 claims description 19
- DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 claims description 18
- PEDCQBHIVMGVHV-UHFFFAOYSA-N glycerol group Chemical group OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims description 17
- 239000000203 mixture Substances 0.000 claims description 9
- 235000011187 glycerol Nutrition 0.000 claims description 8
- 229920000663 Hydroxyethyl cellulose Polymers 0.000 claims description 7
- 239000000654 additive Substances 0.000 claims description 7
- 239000003814 drug Substances 0.000 claims description 7
- 235000019447 hydroxyethyl cellulose Nutrition 0.000 claims description 7
- 229920003169 water-soluble polymer Polymers 0.000 claims description 7
- 238000001035 drying Methods 0.000 claims description 6
- 235000010413 sodium alginate Nutrition 0.000 claims description 6
- 239000000661 sodium alginate Substances 0.000 claims description 6
- 229920002678 cellulose Polymers 0.000 claims description 5
- 239000001913 cellulose Substances 0.000 claims description 5
- 239000004354 Hydroxyethyl cellulose Substances 0.000 claims description 4
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 claims description 4
- 230000000996 additive effect Effects 0.000 claims description 4
- 239000001768 carboxy methyl cellulose Substances 0.000 claims description 4
- 229920001223 polyethylene glycol Polymers 0.000 claims description 4
- 229910052708 sodium Inorganic materials 0.000 claims description 4
- FBPFZTCFMRRESA-FSIIMWSLSA-N D-Glucitol Natural products OC[C@H](O)[C@H](O)[C@@H](O)[C@H](O)CO FBPFZTCFMRRESA-FSIIMWSLSA-N 0.000 claims description 3
- 229920002683 Glycosaminoglycan Polymers 0.000 claims description 3
- 108060003393 Granulin Proteins 0.000 claims description 3
- 239000002202 Polyethylene glycol Substances 0.000 claims description 3
- 150000004676 glycans Chemical class 0.000 claims description 3
- 229920001282 polysaccharide Polymers 0.000 claims description 3
- 239000005017 polysaccharide Substances 0.000 claims description 3
- 235000010408 potassium alginate Nutrition 0.000 claims description 3
- 239000000737 potassium alginate Substances 0.000 claims description 3
- MZYRDLHIWXQJCQ-YZOKENDUSA-L potassium alginate Chemical compound [K+].[K+].O1[C@@H](C([O-])=O)[C@@H](OC)[C@H](O)[C@H](O)[C@@H]1O[C@@H]1[C@@H](C([O-])=O)O[C@@H](O)[C@@H](O)[C@H]1O MZYRDLHIWXQJCQ-YZOKENDUSA-L 0.000 claims description 3
- 239000000600 sorbitol Substances 0.000 claims description 3
- CPKVUHPKYQGHMW-UHFFFAOYSA-N 1-ethenylpyrrolidin-2-one;molecular iodine Chemical compound II.C=CN1CCCC1=O CPKVUHPKYQGHMW-UHFFFAOYSA-N 0.000 claims description 2
- QTBSBXVTEAMEQO-UHFFFAOYSA-M Acetate Chemical compound CC([O-])=O QTBSBXVTEAMEQO-UHFFFAOYSA-M 0.000 claims description 2
- 229920002134 Carboxymethyl cellulose Polymers 0.000 claims description 2
- GHXZTYHSJHQHIJ-UHFFFAOYSA-N Chlorhexidine Chemical compound C=1C=C(Cl)C=CC=1NC(N)=NC(N)=NCCCCCCN=C(N)N=C(N)NC1=CC=C(Cl)C=C1 GHXZTYHSJHQHIJ-UHFFFAOYSA-N 0.000 claims description 2
- WJLVQTJZDCGNJN-UHFFFAOYSA-N Chlorhexidine hydrochloride Chemical compound Cl.Cl.C=1C=C(Cl)C=CC=1NC(N)=NC(N)=NCCCCCCN=C(N)N=C(N)NC1=CC=C(Cl)C=C1 WJLVQTJZDCGNJN-UHFFFAOYSA-N 0.000 claims description 2
- FBPFZTCFMRRESA-JGWLITMVSA-N D-glucitol Chemical compound OC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-JGWLITMVSA-N 0.000 claims description 2
- RGHNJXZEOKUKBD-SQOUGZDYSA-M D-gluconate Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C([O-])=O RGHNJXZEOKUKBD-SQOUGZDYSA-M 0.000 claims description 2
- 102000004190 Enzymes Human genes 0.000 claims description 2
- 108090000790 Enzymes Proteins 0.000 claims description 2
- 229920000153 Povidone-iodine Polymers 0.000 claims description 2
- RHJVJSBJAPQUOS-UHFFFAOYSA-N [S].[Ag].C1=CC=NN=C1 Chemical compound [S].[Ag].C1=CC=NN=C1 RHJVJSBJAPQUOS-UHFFFAOYSA-N 0.000 claims description 2
- 235000010443 alginic acid Nutrition 0.000 claims description 2
- 229920000615 alginic acid Polymers 0.000 claims description 2
- 239000007864 aqueous solution Substances 0.000 claims description 2
- 235000010948 carboxy methyl cellulose Nutrition 0.000 claims description 2
- 229960001927 cetylpyridinium chloride Drugs 0.000 claims description 2
- YMKDRGPMQRFJGP-UHFFFAOYSA-M cetylpyridinium chloride Chemical compound [Cl-].CCCCCCCCCCCCCCCC[N+]1=CC=CC=C1 YMKDRGPMQRFJGP-UHFFFAOYSA-M 0.000 claims description 2
- 229960003260 chlorhexidine Drugs 0.000 claims description 2
- 229960002152 chlorhexidine acetate Drugs 0.000 claims description 2
- 229960003333 chlorhexidine gluconate Drugs 0.000 claims description 2
- 229960004504 chlorhexidine hydrochloride Drugs 0.000 claims description 2
- 239000003102 growth factor Substances 0.000 claims description 2
- 239000003589 local anesthetic agent Substances 0.000 claims description 2
- 229920001451 polypropylene glycol Polymers 0.000 claims description 2
- 229960001621 povidone-iodine Drugs 0.000 claims description 2
- 150000003242 quaternary ammonium salts Chemical class 0.000 claims description 2
- 239000004520 water soluble gel Substances 0.000 claims description 2
- FHVDTGUDJYJELY-UHFFFAOYSA-N 6-{[2-carboxy-4,5-dihydroxy-6-(phosphanyloxy)oxan-3-yl]oxy}-4,5-dihydroxy-3-phosphanyloxane-2-carboxylic acid Chemical compound O1C(C(O)=O)C(P)C(O)C(O)C1OC1C(C(O)=O)OC(OP)C(O)C1O FHVDTGUDJYJELY-UHFFFAOYSA-N 0.000 claims 1
- 229940072056 alginate Drugs 0.000 claims 1
- 239000012928 buffer substance Substances 0.000 claims 1
- 239000008112 carboxymethyl-cellulose Substances 0.000 claims 1
- 206010052428 Wound Diseases 0.000 description 51
- 208000027418 Wounds and injury Diseases 0.000 description 51
- 239000000499 gel Substances 0.000 description 19
- 210000000416 exudates and transudate Anatomy 0.000 description 17
- 230000002745 absorbent Effects 0.000 description 14
- 239000002250 absorbent Substances 0.000 description 14
- 239000000463 material Substances 0.000 description 12
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 9
- 208000025865 Ulcer Diseases 0.000 description 8
- 231100000397 ulcer Toxicity 0.000 description 8
- 230000000694 effects Effects 0.000 description 7
- 239000010410 layer Substances 0.000 description 6
- 238000006467 substitution reaction Methods 0.000 description 5
- 230000029663 wound healing Effects 0.000 description 5
- 230000009471 action Effects 0.000 description 4
- 229910052782 aluminium Inorganic materials 0.000 description 4
- XAGFODPZIPBFFR-UHFFFAOYSA-N aluminium Chemical compound [Al] XAGFODPZIPBFFR-UHFFFAOYSA-N 0.000 description 4
- 239000006172 buffering agent Substances 0.000 description 4
- 235000010410 calcium alginate Nutrition 0.000 description 4
- 239000000648 calcium alginate Substances 0.000 description 4
- 229960002681 calcium alginate Drugs 0.000 description 4
- OKHHGHGGPDJQHR-YMOPUZKJSA-L calcium;(2s,3s,4s,5s,6r)-6-[(2r,3s,4r,5s,6r)-2-carboxy-6-[(2r,3s,4r,5s,6r)-2-carboxylato-4,5,6-trihydroxyoxan-3-yl]oxy-4,5-dihydroxyoxan-3-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylate Chemical compound [Ca+2].O[C@@H]1[C@H](O)[C@H](O)O[C@@H](C([O-])=O)[C@H]1O[C@H]1[C@@H](O)[C@@H](O)[C@H](O[C@H]2[C@H]([C@@H](O)[C@H](O)[C@H](O2)C([O-])=O)O)[C@H](C(O)=O)O1 OKHHGHGGPDJQHR-YMOPUZKJSA-L 0.000 description 4
- 239000006185 dispersion Substances 0.000 description 4
- 229940079593 drug Drugs 0.000 description 4
- 239000000835 fiber Substances 0.000 description 4
- 125000002791 glucosyl group Chemical group C1([C@H](O)[C@@H](O)[C@H](O)[C@H](O1)CO)* 0.000 description 4
- 206010039509 Scab Diseases 0.000 description 3
- DPXJVFZANSGRMM-UHFFFAOYSA-N acetic acid;2,3,4,5,6-pentahydroxyhexanal;sodium Chemical compound [Na].CC(O)=O.OCC(O)C(O)C(O)C(O)C=O DPXJVFZANSGRMM-UHFFFAOYSA-N 0.000 description 3
- 239000012790 adhesive layer Substances 0.000 description 3
- 230000008901 benefit Effects 0.000 description 3
- 238000001816 cooling Methods 0.000 description 3
- 238000010438 heat treatment Methods 0.000 description 3
- 239000007970 homogeneous dispersion Substances 0.000 description 3
- 239000000017 hydrogel Substances 0.000 description 3
- 230000006872 improvement Effects 0.000 description 3
- 239000004014 plasticizer Substances 0.000 description 3
- 238000002360 preparation method Methods 0.000 description 3
- 229940005550 sodium alginate Drugs 0.000 description 3
- 235000019812 sodium carboxymethyl cellulose Nutrition 0.000 description 3
- 229920001027 sodium carboxymethylcellulose Polymers 0.000 description 3
- IXPNQXFRVYWDDI-UHFFFAOYSA-N 1-methyl-2,4-dioxo-1,3-diazinane-5-carboximidamide Chemical compound CN1CC(C(N)=N)C(=O)NC1=O IXPNQXFRVYWDDI-UHFFFAOYSA-N 0.000 description 2
- 230000002378 acidificating effect Effects 0.000 description 2
- 230000001464 adherent effect Effects 0.000 description 2
- 230000000025 haemostatic effect Effects 0.000 description 2
- 230000035876 healing Effects 0.000 description 2
- 239000012456 homogeneous solution Substances 0.000 description 2
- 239000002504 physiological saline solution Substances 0.000 description 2
- 239000003755 preservative agent Substances 0.000 description 2
- 230000002335 preservative effect Effects 0.000 description 2
- 239000011347 resin Substances 0.000 description 2
- 229920005989 resin Polymers 0.000 description 2
- 238000003860 storage Methods 0.000 description 2
- KIUKXJAPPMFGSW-DNGZLQJQSA-N (2S,3S,4S,5R,6R)-6-[(2S,3R,4R,5S,6R)-3-Acetamido-2-[(2S,3S,4R,5R,6R)-6-[(2R,3R,4R,5S,6R)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid Chemical compound CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 KIUKXJAPPMFGSW-DNGZLQJQSA-N 0.000 description 1
- 241000894006 Bacteria Species 0.000 description 1
- 229920001287 Chondroitin sulfate Polymers 0.000 description 1
- 102000008186 Collagen Human genes 0.000 description 1
- 108010035532 Collagen Proteins 0.000 description 1
- 102000016359 Fibronectins Human genes 0.000 description 1
- 108010067306 Fibronectins Proteins 0.000 description 1
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 description 1
- 239000006173 Good's buffer Substances 0.000 description 1
- 229920002971 Heparan sulfate Polymers 0.000 description 1
- 229920000288 Keratan sulfate Polymers 0.000 description 1
- 102000007547 Laminin Human genes 0.000 description 1
- 108010085895 Laminin Proteins 0.000 description 1
- 229920000604 Polyethylene Glycol 200 Polymers 0.000 description 1
- 229920002565 Polyethylene Glycol 400 Polymers 0.000 description 1
- 239000007983 Tris buffer Substances 0.000 description 1
- 238000005299 abrasion Methods 0.000 description 1
- 238000010521 absorption reaction Methods 0.000 description 1
- 239000000853 adhesive Substances 0.000 description 1
- 230000001070 adhesive effect Effects 0.000 description 1
- 150000001413 amino acids Chemical class 0.000 description 1
- 125000000129 anionic group Chemical group 0.000 description 1
- 229940030225 antihemorrhagics Drugs 0.000 description 1
- 125000002091 cationic group Chemical group 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 229940094517 chondroitin 4-sulfate Drugs 0.000 description 1
- KXKPYJOVDUMHGS-OSRGNVMNSA-N chondroitin sulfate Chemical compound CC(=O)N[C@H]1[C@H](O)O[C@H](OS(O)(=O)=O)[C@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](C(O)=O)O1 KXKPYJOVDUMHGS-OSRGNVMNSA-N 0.000 description 1
- 239000011248 coating agent Substances 0.000 description 1
- 238000000576 coating method Methods 0.000 description 1
- 229920001436 collagen Polymers 0.000 description 1
- 239000000084 colloidal system Substances 0.000 description 1
- 238000010276 construction Methods 0.000 description 1
- 238000010924 continuous production Methods 0.000 description 1
- 229920002457 flexible plastic Polymers 0.000 description 1
- 239000012530 fluid Substances 0.000 description 1
- 229920002313 fluoropolymer Polymers 0.000 description 1
- 239000008103 glucose Substances 0.000 description 1
- 229920002674 hyaluronan Polymers 0.000 description 1
- 229960003160 hyaluronic acid Drugs 0.000 description 1
- 230000002209 hydrophobic effect Effects 0.000 description 1
- 208000015181 infectious disease Diseases 0.000 description 1
- 239000002198 insoluble material Substances 0.000 description 1
- KXCLCNHUUKTANI-RBIYJLQWSA-N keratan Chemical compound CC(=O)N[C@@H]1[C@@H](O)C[C@@H](COS(O)(=O)=O)O[C@H]1O[C@@H]1[C@@H](O)[C@H](O[C@@H]2[C@H](O[C@@H](O[C@H]3[C@H]([C@@H](COS(O)(=O)=O)O[C@@H](O)[C@@H]3O)O)[C@H](NC(C)=O)[C@H]2O)COS(O)(=O)=O)O[C@H](COS(O)(=O)=O)[C@@H]1O KXCLCNHUUKTANI-RBIYJLQWSA-N 0.000 description 1
- 238000002483 medication Methods 0.000 description 1
- 230000005499 meniscus Effects 0.000 description 1
- 229910001092 metal group alloy Inorganic materials 0.000 description 1
- 230000000813 microbial effect Effects 0.000 description 1
- 238000002156 mixing Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 238000004806 packaging method and process Methods 0.000 description 1
- 230000001737 promoting effect Effects 0.000 description 1
- 235000013772 propylene glycol Nutrition 0.000 description 1
- 229920006395 saturated elastomer Polymers 0.000 description 1
- 229920005573 silicon-containing polymer Polymers 0.000 description 1
- 229920002379 silicone rubber Polymers 0.000 description 1
- 239000004945 silicone rubber Substances 0.000 description 1
- 239000010935 stainless steel Substances 0.000 description 1
- 229910001220 stainless steel Inorganic materials 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- LENZDBCJOHFCAS-UHFFFAOYSA-N tris Chemical compound OCC(N)(CO)CO LENZDBCJOHFCAS-UHFFFAOYSA-N 0.000 description 1
- 238000005406 washing Methods 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
- A61L26/0009—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form containing macromolecular materials
- A61L26/0023—Polysaccharides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
- A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
- A61L15/22—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing macromolecular materials
- A61L15/28—Polysaccharides or their derivatives
Landscapes
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Materials Engineering (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Hematology (AREA)
- Materials For Medical Uses (AREA)
- Catalysts (AREA)
- Cosmetics (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB919119287A GB9119287D0 (en) | 1991-09-10 | 1991-09-10 | Web dressing and method for its production |
| GB929207239A GB9207239D0 (en) | 1992-04-02 | 1992-04-02 | Web dressing and method for its production |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE69228162D1 DE69228162D1 (de) | 1999-02-25 |
| DE69228162T2 true DE69228162T2 (de) | 1999-07-22 |
Family
ID=26299520
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE69228162T Expired - Fee Related DE69228162T2 (de) | 1991-09-10 | 1992-09-09 | Netzverband und Verfahren zu seiner Herstellung |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US6123958A (enExample) |
| EP (1) | EP0532275B1 (enExample) |
| JP (1) | JP3254013B2 (enExample) |
| AT (1) | ATE175580T1 (enExample) |
| BR (1) | BR9203502A (enExample) |
| CA (1) | CA2077812C (enExample) |
| DE (1) | DE69228162T2 (enExample) |
| ES (1) | ES2127744T3 (enExample) |
| TW (1) | TW290443B (enExample) |
Families Citing this family (33)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2275685B (en) * | 1993-03-03 | 1997-04-30 | Johnson & Johnson Medical | Water soluble wound dressing materials |
| GB2275686B (en) * | 1993-03-03 | 1997-04-30 | Johnson & Johnson Medical | Swellable wound dressing materials |
| GB2276819B (en) * | 1993-03-23 | 1996-12-11 | Johnson & Johnson Medical | Aqueous wound treatment composition comprising a polysaccharide and hexylene glycol |
| US5670169A (en) * | 1993-12-20 | 1997-09-23 | E.R. Squibb & Sons, Inc. | Wound hydrating gel with novel preservative system and low cytotoxicity |
| GB9401279D0 (en) * | 1994-01-24 | 1994-03-23 | Bristol Myers Squibb Co | Wound dressing |
| GB2291348B (en) * | 1994-07-18 | 1999-01-20 | Johnson & Johnson Medical | Sterile gel composition for wound treatment comprising alginate and polyhydric alcohol |
| DE19712699C2 (de) * | 1997-03-26 | 2000-05-25 | Thueringisches Inst Textil | Verfahren zur Herstellung von Wundschnellverbänden mit wundversorgungsaktiven Stoffen |
| GB9812278D0 (en) * | 1998-06-09 | 1998-08-05 | Bristol Myers Squibb Co | Use of a wound dressing in the treatment of acute wounds |
| ATE260669T1 (de) † | 1999-12-09 | 2004-03-15 | Apimed Medical Honey Ltd | Medizinische verbände enthaltend gelartiger honig |
| GB2387331B (en) * | 2002-04-12 | 2005-03-23 | Johnson & Johnson Medical Ltd | Apertured hydrogel sheets |
| EP1503736A1 (en) * | 2002-04-25 | 2005-02-09 | Fmc Corporation | Air treatment gel and method for its preparation |
| US20050182443A1 (en) | 2004-02-18 | 2005-08-18 | Closure Medical Corporation | Adhesive-containing wound closure device and method |
| US20060009099A1 (en) | 2004-07-12 | 2006-01-12 | Closure Medical Corporation | Adhesive-containing wound closure device and method |
| DE102006001954B4 (de) * | 2006-01-16 | 2013-01-03 | Lohmann & Rauscher Gmbh & Co. Kg | Antiseptische Alginatzubereitung, Verfahren zu deren Herstellung, sowie deren Verwendung |
| US8329976B2 (en) | 2007-06-04 | 2012-12-11 | Coloplast A/S | Method for manufacturing a net patterned adhesive layer |
| US8049948B2 (en) * | 2007-06-08 | 2011-11-01 | Konica Minolta Holdings, Inc. | Process for producing electrochemical display element and electrochemical display element |
| GB0810404D0 (en) | 2008-06-06 | 2008-07-09 | Manuka Medical Ltd | Compositions |
| US20100310621A1 (en) * | 2009-06-04 | 2010-12-09 | Richards James C | Controlled Iodine Release Particle Micro-Biocide |
| KR101070358B1 (ko) | 2009-12-24 | 2011-10-05 | 한국생산기술연구원 | 의료용 부직포 및 그의 제조방법 |
| US20110171284A1 (en) * | 2010-01-11 | 2011-07-14 | Gilman Miles E | Povidone-iodine and sucrose wound healing dressing |
| ITTO20120258A1 (it) * | 2012-03-21 | 2013-09-22 | Fond Istituto Italiano Di Tecnologia | Materiali compositi polimerici con proprieta' antimicrobiche e biodegradabili e loro usi. |
| USD824525S1 (en) | 2014-09-25 | 2018-07-31 | Ethicon Llc | Release paper for wound treament devices |
| JP6871855B2 (ja) | 2014-10-14 | 2021-05-19 | サムエル リンチ， | 創傷を処置するための組成物 |
| US10792024B2 (en) | 2016-09-28 | 2020-10-06 | Ethicon, Inc. | Scaffolds with channels for joining layers of tissue at discrete points |
| USD848624S1 (en) | 2016-09-29 | 2019-05-14 | Ethicon, Inc. | Release paper for wound treatment devices |
| US10687986B2 (en) | 2016-09-29 | 2020-06-23 | Ethicon, Inc. | Methods and devices for skin closure |
| US10470935B2 (en) | 2017-03-23 | 2019-11-12 | Ethicon, Inc. | Skin closure systems and devices of improved flexibility and stretchability for bendable joints |
| US11504446B2 (en) | 2017-04-25 | 2022-11-22 | Ethicon, Inc. | Skin closure devices with self-forming exudate drainage channels |
| US10993708B2 (en) | 2018-07-31 | 2021-05-04 | Ethicon, Inc. | Skin closure devices with interrupted closure |
| GB2588440A (en) | 2019-10-24 | 2021-04-28 | Io Cyte Ltd | Swellable antimicrobial fibre |
| GB2588439A (en) | 2019-10-24 | 2021-04-28 | Io Cyte Ltd | Swellable antimicrobial fibre |
| GB2588442A (en) | 2019-10-24 | 2021-04-28 | Io Cyte Ltd | Antimicrobial material |
| CN114848886A (zh) * | 2022-06-08 | 2022-08-05 | 扬州卓和医用材料有限公司 | 一种可吸收性止血敷料 |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3122479A (en) * | 1957-11-14 | 1964-02-25 | David F Smith | Hemostatic surgical dressings |
| GB942305A (en) * | 1958-12-23 | 1963-11-20 | Parachem Corp | Improvements in or relating to antiseptic film and method and apparatus for producing the same |
| US3876771A (en) * | 1973-09-04 | 1975-04-08 | Hallister Inc | Skin protective gel containing polyvinyl methylether or monoisopropyl ester of polyvinyl methylether maleic acid |
| DE2908437A1 (de) * | 1979-03-05 | 1980-09-18 | Fresenius Chem Pharm Ind | Vernetzte hydroxyaethylstaerke |
| EP0075791B1 (de) * | 1981-09-30 | 1986-04-09 | VEB Leipziger Arzneimittelwerk | Absorbierender Wundverband und Verfahren zu seiner Herstellung |
| JPS58206751A (ja) * | 1982-05-26 | 1983-12-02 | 日石三菱株式会社 | 創傷被覆材 |
| US4588400A (en) * | 1982-12-16 | 1986-05-13 | Johnson & Johnson Products, Inc. | Liquid loaded pad for medical applications |
| GB8422950D0 (en) * | 1984-09-11 | 1984-10-17 | Warne K J | Hydrogel |
| SE455466C (sv) * | 1986-03-10 | 1993-07-05 | Moelnlycke Ab | Foerband foer vaetskande saar |
| GB2192142B (en) * | 1986-07-04 | 1990-11-28 | Johnson & Johnson | Wound dressing |
| US4931551A (en) * | 1988-07-05 | 1990-06-05 | University Of Delaware | Dispersions of chitin and product therefrom |
| DE3827561C1 (enExample) * | 1988-08-13 | 1989-12-28 | Lts Lohmann Therapie-Systeme Gmbh & Co Kg, 5450 Neuwied, De | |
| US5156601A (en) * | 1991-03-20 | 1992-10-20 | Hydromer, Inc. | Tacky, hydrophilic gel dressings and products therefrom |
| GB9105995D0 (en) * | 1991-03-21 | 1991-05-08 | Smith & Nephew | Wound dressing |
-
1992
- 1992-09-08 JP JP26413692A patent/JP3254013B2/ja not_active Expired - Fee Related
- 1992-09-09 DE DE69228162T patent/DE69228162T2/de not_active Expired - Fee Related
- 1992-09-09 CA CA002077812A patent/CA2077812C/en not_active Expired - Fee Related
- 1992-09-09 AT AT92308148T patent/ATE175580T1/de not_active IP Right Cessation
- 1992-09-09 EP EP92308148A patent/EP0532275B1/en not_active Expired - Lifetime
- 1992-09-09 BR BR929203502A patent/BR9203502A/pt not_active IP Right Cessation
- 1992-09-09 ES ES92308148T patent/ES2127744T3/es not_active Expired - Lifetime
- 1992-10-03 TW TW081107856A patent/TW290443B/zh active
-
1997
- 1997-12-09 US US08/987,752 patent/US6123958A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| TW290443B (enExample) | 1996-11-11 |
| DE69228162D1 (de) | 1999-02-25 |
| EP0532275A1 (en) | 1993-03-17 |
| ES2127744T3 (es) | 1999-05-01 |
| US6123958A (en) | 2000-09-26 |
| CA2077812C (en) | 2004-11-09 |
| ATE175580T1 (de) | 1999-01-15 |
| CA2077812A1 (en) | 1993-03-11 |
| JPH05220209A (ja) | 1993-08-31 |
| EP0532275B1 (en) | 1999-01-13 |
| JP3254013B2 (ja) | 2002-02-04 |
| BR9203502A (pt) | 1993-04-13 |
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