DE69216952D1 - Optische Spaltung von (+/-)-2-(4-Isobutylphenyl)propionsäure - Google Patents

Optische Spaltung von (+/-)-2-(4-Isobutylphenyl)propionsäure

Info

Publication number
DE69216952D1
DE69216952D1 DE69216952T DE69216952T DE69216952D1 DE 69216952 D1 DE69216952 D1 DE 69216952D1 DE 69216952 T DE69216952 T DE 69216952T DE 69216952 T DE69216952 T DE 69216952T DE 69216952 D1 DE69216952 D1 DE 69216952D1
Authority
DE
Germany
Prior art keywords
isobutylphenyl
propionic acid
optical resolution
chem
optically active
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69216952T
Other languages
English (en)
Other versions
DE69216952T2 (de
Inventor
Hiroyuki Nohira
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nagase and Co Ltd
Original Assignee
Nagase and Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nagase and Co Ltd filed Critical Nagase and Co Ltd
Publication of DE69216952D1 publication Critical patent/DE69216952D1/de
Application granted granted Critical
Publication of DE69216952T2 publication Critical patent/DE69216952T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B57/00—Separation of optically-active compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/42—Separation; Purification; Stabilisation; Use of additives
    • C07C51/487—Separation; Purification; Stabilisation; Use of additives by treatment giving rise to chemical modification

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DE69216952T 1991-08-23 1992-08-05 Optische Spaltung von (+/-)-2-(4-Isobutylphenyl)propionsäure Expired - Fee Related DE69216952T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP23721091 1991-08-23

Publications (2)

Publication Number Publication Date
DE69216952D1 true DE69216952D1 (de) 1997-03-06
DE69216952T2 DE69216952T2 (de) 1997-07-10

Family

ID=17012017

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69216952T Expired - Fee Related DE69216952T2 (de) 1991-08-23 1992-08-05 Optische Spaltung von (+/-)-2-(4-Isobutylphenyl)propionsäure

Country Status (8)

Country Link
US (1) US5321154A (de)
EP (1) EP0529835B1 (de)
JP (1) JP3135696B2 (de)
AT (1) ATE148089T1 (de)
CA (1) CA2074932A1 (de)
DE (1) DE69216952T2 (de)
DK (1) DK0529835T3 (de)
ES (1) ES2096724T3 (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5602272A (en) * 1994-06-21 1997-02-11 Bristol-Myers Squibb Company Reduction and resolution methods for the preparation of compounds useful as intemediates for preparing taxanes
JPH08151344A (ja) * 1994-09-26 1996-06-11 Nagase & Co Ltd ２−（３−ベンゾイルフェニル）プロピオン酸の光学分割方法
US5621140A (en) * 1994-12-22 1997-04-15 Syntex (U.S.A.) Inc. Resolution of ibuprofen
DE19624604A1 (de) * 1996-06-20 1998-01-02 Hoechst Ag Verfahren zur Herstellung chiraler, nicht racemischer (4-Aryl-2,5-dioxoimidazolidin-1-yl)essigsäuren
IN183408B (de) * 1996-11-20 1999-12-25 Kuraray Co
JP2000080062A (ja) * 1998-07-09 2000-03-21 Sumitomo Chem Co Ltd 光学活性１―アリ―ルアルキルアミン類の製造方法およびその中間体
AU2009315280A1 (en) * 2008-11-14 2010-05-20 Watson Pharma Private Limited Process for the preparation of ramelteon

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4209638A (en) * 1977-03-08 1980-06-24 The Boots Company Limited Preparation of therapeutic agents
GB1596033A (en) * 1978-04-25 1981-08-19 Boots Co Ltd (-)-(2-methoxyphenyl) ethylamine
US4723033A (en) * 1982-11-24 1988-02-02 Syntex Pharmaceuticals International Ltd. Manufacture of optically active α-arylalkanoic acids and precursors thereof
JPS59152346A (ja) * 1983-02-18 1984-08-31 Hiroyuki Nohira 光学活性２−（６−メトキシ−２−ナフチル）プロピオン酸の製造法
JPS60228442A (ja) * 1984-04-27 1985-11-13 Nissan Chem Ind Ltd 光学活性２−（６−メトキシ−２−ナフチル）プロピオン酸の製造法
JPS61172853A (ja) * 1985-01-29 1986-08-04 Hiroyuki Nohira （±）−トランス−菊カルボン酸の光学分割法
JPH0684332B2 (ja) * 1985-06-20 1994-10-26 住友化学工業株式会社 ａ−イソプロピル−ｐ−クロルフエニル酢酸の光学分割法
JPS63227543A (ja) * 1987-03-17 1988-09-21 Nippon Kayaku Co Ltd 光学活性２−（６−メトキシ−２−ナフチル）プロピオン酸の製造法
JP2792046B2 (ja) * 1987-10-09 1998-08-27 住友化学工業株式会社 光学活性なアミン−ホウ素系化合物、それを有効成分とする不斉還元剤ならびにそれを用いる光学活性化合物の製造方法
DE3824353A1 (de) * 1988-07-19 1990-01-25 Paz Arzneimittelentwicklung Verfahren zur trennung von gemischen enantiomerer arylpropionsaeuren
US5191112A (en) * 1989-10-17 1993-03-02 Nissan Chemical Industries, Ltd. Process for optical resolution of (±)-2-(3-benzoyl)-phenylpropionic acid
US5015764A (en) * 1990-06-18 1991-05-14 Ethyl Corporation Preparation of optically active aliphatic carboxylic acids

Also Published As

Publication number Publication date
DE69216952T2 (de) 1997-07-10
EP0529835A2 (de) 1993-03-03
US5321154A (en) 1994-06-14
EP0529835A3 (de) 1993-04-28
ES2096724T3 (es) 1997-03-16
DK0529835T3 (da) 1997-06-30
ATE148089T1 (de) 1997-02-15
JP3135696B2 (ja) 2001-02-19
CA2074932A1 (en) 1993-02-24
JPH05229986A (ja) 1993-09-07
EP0529835B1 (de) 1997-01-22

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee