ES2082774T3 - Compuestos macrolidos. - Google Patents

Compuestos macrolidos.

Info

Publication number
ES2082774T3
ES2082774T3 ES89304673T ES89304673T ES2082774T3 ES 2082774 T3 ES2082774 T3 ES 2082774T3 ES 89304673 T ES89304673 T ES 89304673T ES 89304673 T ES89304673 T ES 89304673T ES 2082774 T3 ES2082774 T3 ES 2082774T3
Authority
ES
Spain
Prior art keywords
group
hydrogen atom
compounds
hydroxyl group
ch2oh
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES89304673T
Other languages
English (en)
Inventor
Michael John Dawson
David Noble
Gordon C Lawrence
Richard A Fletton
Stephen Joseph Lane
Michael V J Ramsay
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wyeth Holdings LLC
Original Assignee
American Cyanamid Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB888811034A external-priority patent/GB8811034D0/en
Priority claimed from GB888811035A external-priority patent/GB8811035D0/en
Application filed by American Cyanamid Co filed Critical American Cyanamid Co
Application granted granted Critical
Publication of ES2082774T3 publication Critical patent/ES2082774T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D493/00Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/22Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains four or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/01Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing oxygen
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/90Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having two or more relevant hetero rings, condensed among themselves or with a common carbocyclic ring system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • A61P33/10Anthelmintics

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Dentistry (AREA)
  • Wood Science & Technology (AREA)
  • Agronomy & Crop Science (AREA)
  • Pest Control & Pesticides (AREA)
  • Plant Pathology (AREA)
  • Biochemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Pyrane Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Furan Compounds (AREA)
  • Devices For Conveying Motion By Means Of Endless Flexible Members (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pyrrole Compounds (AREA)

Abstract

COMPUESTOS DE LA FORMULA I Y SALES DE ESTO, DONDE R EXP1 REPRESENTA UN GRUPO METILO, ETILO, O ISOPROPILO; Y EXP1 ES - CH2 -, Y (AL CUADRADO) ES - CH - Y X REPRESENTA (II), DONDE R (AL CUADRADO) ES UN ATOMO DE HIDROGENO O UN GRUPO OR EXP8 (SIENDO OR EXP8 UN GRUPO HIDROXILO O UN GRUPO HIDROXILO SUSTITUIDO CON HASTA 25 ATOMOS DE CARBONO) Y R EXP3 ES UN ATOMO DE HIDROGENO O R (AL CUADRADO) Y R EXP3 JUNTO CON EL ATOMO DE CARBONO AL QUE ESTAN UNIDOS REPRESENTAN > C = 0, > C = CH2 O > C = NOR EXP9 (DONDE R EXP9 REPRESENTA UN ATOMO DE HIDROGENO, UN GRUPO C1 - 8 ALQUILO O UN GRUPO ALQUENILO C3 - 8) Y EL GRUPO > C = NOR EXP9 ESTA EN LA CONFIGURACION E); R EXP4 REPRESENTA UN GRUPO OR EXP8 COMO SE DEFINE ARRIBA Y R EXP5 REPRESENTA UN ATOMO DE HIDROGENO, O R EXP4 Y R EXP5 JUNTOS CON EL ATOMO DE CARBONO AL QUE ESTAN UNIDOS REPRESENTAN > C = 0 O > C = NOR EXP9A; R EXP6 ES UN HIDROGENO Y R EXP6 ES - CH2OH, - CHO, - CO2H O UN GRUPO AMIDA O ESTER DE ACIDO CARBOXILICO; R EXP6 ES HIDROXILO Y R UN GRUPO METILO; R EXP7 ES UN ATOMO DE HIDROGENO O UN GRUPO HIDROXILO. LOS COMPUESTOS SON UTILES PARA CONTROLAR NEMATODOS, ACARINA, INSECTOS Y OTRAS PLAGAS.
ES89304673T 1988-05-10 1989-05-09 Compuestos macrolidos. Expired - Lifetime ES2082774T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB888811034A GB8811034D0 (en) 1988-05-10 1988-05-10 Chemical compounds
GB888811035A GB8811035D0 (en) 1988-05-10 1988-05-10 Chemical compounds

Publications (1)

Publication Number Publication Date
ES2082774T3 true ES2082774T3 (es) 1996-04-01

Family

ID=26293876

Family Applications (1)

Application Number Title Priority Date Filing Date
ES89304673T Expired - Lifetime ES2082774T3 (es) 1988-05-10 1989-05-09 Compuestos macrolidos.

Country Status (16)

Country Link
US (1) US5057536A (es)
EP (1) EP0341974B1 (es)
JP (1) JP2629047B2 (es)
KR (1) KR960013442B1 (es)
AT (1) ATE133416T1 (es)
AU (1) AU628051B2 (es)
BR (1) BR8902167A (es)
CA (1) CA1318629C (es)
DE (1) DE68925494T2 (es)
DK (1) DK227289A (es)
ES (1) ES2082774T3 (es)
GR (1) GR3019116T3 (es)
HU (2) HU9203978D0 (es)
IE (1) IE72215B1 (es)
NZ (1) NZ229052A (es)
PT (1) PT90506B (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ233680A (en) * 1989-05-17 1995-02-24 Beecham Group Plc Avermectins and milbemycins and compositions thereof
US4988824A (en) * 1989-09-11 1991-01-29 Maulding Donald R Process for the preparation of 23-(C1-C6 alkyloxime)-LL-F28249 compounds

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS59108785A (ja) * 1982-11-25 1984-06-23 Sankyo Co Ltd ミルベマイシン類の5−オキシム誘導体
US4857509A (en) * 1985-01-22 1989-08-15 Ciba-Geigy Corporation 13β-alkylmilbemycin derivatives for controlling parasites of animals and plants
US4666937A (en) * 1985-03-04 1987-05-19 Merck & Co., Inc. Avermectin bioconversion products
ES8802229A1 (es) * 1985-04-30 1988-04-16 Glaxo Group Ltd Un procedimiento para preparar nuevos derivados lactonicos macrociclicos.
CA1296328C (en) * 1986-03-12 1992-02-25 Derek R. Sutherland Macrolide compounds
US4886828A (en) * 1986-09-12 1989-12-12 American Cyanamid Company Δ22 -derivatives of LL-F28249 compounds
ES2058082T3 (es) * 1986-09-12 1994-11-01 American Cyanamid Co Derivados 23-oxo (ceto) y 23-imino de compuestos ll-f28249.
US5149832A (en) * 1986-09-12 1992-09-22 American Cyanamid Company Mono and diacyl derivatives of ll-f28249 compounds
US4831016A (en) * 1986-10-31 1989-05-16 Merck & Co., Inc. Reduced avermectin derivatives
GB8811037D0 (en) * 1988-05-10 1988-06-15 Glaxo Group Ltd Chemical compounds
US4906619A (en) * 1988-07-22 1990-03-06 Merck & Co., Inc. Alkyl avermectin derivatives

Also Published As

Publication number Publication date
IE72215B1 (en) 1997-04-09
GR3019116T3 (en) 1996-05-31
BR8902167A (pt) 1990-01-02
KR960013442B1 (ko) 1996-10-05
IE891506L (en) 1989-11-10
DE68925494T2 (de) 1996-11-07
DK227289D0 (da) 1989-05-09
DE68925494D1 (de) 1996-03-07
KR900018109A (ko) 1990-12-20
ATE133416T1 (de) 1996-02-15
HU9203978D0 (en) 1993-04-28
NZ229052A (en) 1991-03-26
HUT54371A (en) 1991-02-28
DK227289A (da) 1989-11-11
US5057536A (en) 1991-10-15
AU3457489A (en) 1989-11-16
AU628051B2 (en) 1992-09-10
EP0341974A2 (en) 1989-11-15
JPH0215086A (ja) 1990-01-18
PT90506A (pt) 1989-11-30
EP0341974B1 (en) 1996-01-24
JP2629047B2 (ja) 1997-07-09
EP0341974A3 (en) 1991-01-30
PT90506B (pt) 1994-08-31
CA1318629C (en) 1993-06-01
HU206720B (en) 1992-12-28

Similar Documents

Publication Publication Date Title
ES2061487T3 (es) Compuestos macrolidos.
ES2059365T3 (es) Compuestos macrolidos.
ES2094729T3 (es) Compuestos macrolidos.
ES2118709T3 (es) Compuestos macrolidos.
ES2082774T3 (es) Compuestos macrolidos.
ES2091761T3 (es) Compuestos macrolidos.

Legal Events

Date Code Title Description
FG2A Definitive protection

Ref document number: 341974

Country of ref document: ES