ES2091761T3 - Compuestos macrolidos. - Google Patents

Compuestos macrolidos.

Info

Publication number
ES2091761T3
ES2091761T3 ES89304671T ES89304671T ES2091761T3 ES 2091761 T3 ES2091761 T3 ES 2091761T3 ES 89304671 T ES89304671 T ES 89304671T ES 89304671 T ES89304671 T ES 89304671T ES 2091761 T3 ES2091761 T3 ES 2091761T3
Authority
ES
Spain
Prior art keywords
group
hydrogen atom
atom
defined above
compounds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES89304671T
Other languages
English (en)
Inventor
Michael V J Ramsay
Richard Bell
Peter D Howes
Edward P Tiley
Derek R Sutherland
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wyeth Holdings LLC
Original Assignee
American Cyanamid Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by American Cyanamid Co filed Critical American Cyanamid Co
Application granted granted Critical
Publication of ES2091761T3 publication Critical patent/ES2091761T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/22—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains four or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/01—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing oxygen
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/90—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having two or more relevant hetero rings, condensed among themselves or with a common carbocyclic ring system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/10—Anthelmintics
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F02—COMBUSTION ENGINES; HOT-GAS OR COMBUSTION-PRODUCT ENGINE PLANTS
    • F02M—SUPPLYING COMBUSTION ENGINES IN GENERAL WITH COMBUSTIBLE MIXTURES OR CONSTITUENTS THEREOF
    • F02M7/00—Carburettors with means for influencing, e.g. enriching or keeping constant, fuel/air ratio of charge under varying conditions

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Dentistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Agronomy & Crop Science (AREA)
  • Pest Control & Pesticides (AREA)
  • Plant Pathology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • Mechanical Engineering (AREA)
  • General Engineering & Computer Science (AREA)
  • Combustion & Propulsion (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Devices For Conveying Motion By Means Of Endless Flexible Members (AREA)
  • Furan Compounds (AREA)
  • Pyrane Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

COMPUESTOS DE LA FORMULA (I) DONDE R EXP1 REPRESENTA UN GRUPO METILO, ETILO O ISOPROPILO; Y EXP1 ES - CH2 -, Y (AL CUADRADO) ES - CH - Y X REPRESENTA II, DONDE R (AL CUADRADO) REPRESENTA UN ATOMO DE HIDROGENO O UN GRUPO OR EXP6, (DONDE OR EXP6 ES UN GRUPO HIDROXI O UN GRUPO HIDROXILO SUSTITUIDO CON HASTA 25 ATOMOS DE CARBONO) Y R EXP3 REPRESENTA UN ATOMO DE HIDROGENO, O R (AL CUADRADO) Y R EXP3 JUNTOS CON EL ATOMO DE CARBONO AL QUE ESTAN UNIDOS REPRESENTAN > C = 0, > C = CH2 O > C = NOR EXP7 (DONDE R EXP7 REPRESENTA UN ATOMO DE HIDROGENO, UN GRUPO ALQUILO C1 - 8 O UN GRUPO ALQUENILO C3 - 8 Y EL GRUPO > C = NOR EXP7 ESTA EN LA CONFIGURACION E); R EXP4 REPRESENTA UN GRUPO OR EXP6 COMO SE DEFINE ARRIBA Y R EXP5 REPRESENTA UN ATOMO DE HIDROGENO, O R EXP4 Y R EXP5 JUNTOS CON EL ATOMO DE CARBONO AL QUE ESTAN UNIDOS REPRESENTAN > C = 0 O > C = NOR EXP7A, (DONDE R EXP7A ES COMO SE DEFINE ARRIBA PARA R EXP7) Y R EXP8 Y R EXP9 TIENEN EL SIGNIFICADO DADO EN LA INVENCION. ESTOS COMPUESTOS SON UTILESPARA CONTROLAR NEMATODOS, ACAMINA, INSECTOS Y OTROS PLAGUICIDAS.
ES89304671T 1988-05-10 1989-05-09 Compuestos macrolidos. Expired - Lifetime ES2091761T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB888811037A GB8811037D0 (en) 1988-05-10 1988-05-10 Chemical compounds

Publications (1)

Publication Number Publication Date
ES2091761T3 true ES2091761T3 (es) 1996-11-16

Family

ID=10636654

Family Applications (1)

Application Number Title Priority Date Filing Date
ES89304671T Expired - Lifetime ES2091761T3 (es) 1988-05-10 1989-05-09 Compuestos macrolidos.

Country Status (18)

Country Link
US (1) US5112854A (es)
EP (1) EP0341972B1 (es)
JP (1) JP2506189B2 (es)
KR (1) KR960013441B1 (es)
AT (1) ATE142211T1 (es)
AU (1) AU631792B2 (es)
BR (1) BR8902169A (es)
CA (1) CA1333599C (es)
DD (1) DD289531A5 (es)
DE (1) DE68927070T2 (es)
DK (1) DK171025B1 (es)
ES (1) ES2091761T3 (es)
GB (1) GB8811037D0 (es)
GR (1) GR3021375T3 (es)
HU (1) HU204833B (es)
NZ (1) NZ229051A (es)
PT (1) PT90508B (es)
ZA (1) ZA893428B (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2629047B2 (ja) * 1988-05-10 1997-07-09 アメリカン・サイアナミツド・カンパニー マクロライド化合物
NZ233680A (en) * 1989-05-17 1995-02-24 Beecham Group Plc Avermectins and milbemycins and compositions thereof
US5614470A (en) * 1994-04-01 1997-03-25 Sankyo Company, Limited 13-substituted milbemycin derivatives, their preparation and their use
GB0229804D0 (en) * 2002-12-20 2003-01-29 Syngenta Participations Ag Avermection b1 and avermectin b1 monosaccharide derivatives having an alkoxymethyl substituent in the 4"- or 4'-position

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4579864A (en) * 1984-06-11 1986-04-01 Merck & Co., Inc. Avermectin and milbemycin 13-keto, 13-imino and 13-amino derivatives
HUT39739A (en) * 1984-12-04 1986-10-29 Ciba Geigy Ag Process for production of derivatives of 13,3-milbemycin and medical preparatives containing thereof
US4587247A (en) * 1985-02-25 1986-05-06 Merck & Co., Inc. Substituted and unsubstituted 13-(alkoxy)methoxy derivatives of the avermectin aglycones, compositions and use
ES8802229A1 (es) * 1985-04-30 1988-04-16 Glaxo Group Ltd Un procedimiento para preparar nuevos derivados lactonicos macrociclicos.
CA1296328C (en) * 1986-03-12 1992-02-25 Derek R. Sutherland Macrolide compounds
ES2058082T3 (es) * 1986-09-12 1994-11-01 American Cyanamid Co Derivados 23-oxo (ceto) y 23-imino de compuestos ll-f28249.
US4806527A (en) * 1987-03-16 1989-02-21 Merck & Co., Inc. Avermectin derivatives

Also Published As

Publication number Publication date
DE68927070T2 (de) 1997-03-06
NZ229051A (en) 1991-07-26
DK171025B1 (da) 1996-04-22
AU631792B2 (en) 1992-12-10
JPH0262882A (ja) 1990-03-02
EP0341972A3 (en) 1991-01-30
KR890017251A (ko) 1989-12-15
PT90508A (pt) 1989-11-30
AU3457289A (en) 1989-11-16
EP0341972A2 (en) 1989-11-15
HUT54373A (en) 1991-02-28
DE68927070D1 (de) 1996-10-10
DK227389A (da) 1989-11-11
ATE142211T1 (de) 1996-09-15
PT90508B (pt) 1994-08-31
JP2506189B2 (ja) 1996-06-12
ZA893428B (en) 1990-03-28
HU204833B (en) 1992-02-28
CA1333599C (en) 1994-12-20
DK227389D0 (da) 1989-05-09
DD289531A5 (de) 1991-05-02
GR3021375T3 (en) 1997-01-31
KR960013441B1 (ko) 1996-10-05
GB8811037D0 (en) 1988-06-15
US5112854A (en) 1992-05-12
BR8902169A (pt) 1990-01-02
EP0341972B1 (en) 1996-09-04

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