DE69213713T2 - Leitfaehigkeit-servodosierungsystem zur hemodialyse - Google Patents
Leitfaehigkeit-servodosierungsystem zur hemodialyseInfo
- Publication number
- DE69213713T2 DE69213713T2 DE69213713T DE69213713T DE69213713T2 DE 69213713 T2 DE69213713 T2 DE 69213713T2 DE 69213713 T DE69213713 T DE 69213713T DE 69213713 T DE69213713 T DE 69213713T DE 69213713 T2 DE69213713 T2 DE 69213713T2
- Authority
- DE
- Germany
- Prior art keywords
- conductivity
- dialysate
- measured
- further characterized
- calculated
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Revoked
Links
- 238000001631 haemodialysis Methods 0.000 title claims description 8
- 230000000322 hemodialysis Effects 0.000 title claims description 8
- 239000012141 concentrate Substances 0.000 claims description 66
- BVKZGUZCCUSVTD-UHFFFAOYSA-M Bicarbonate Chemical compound OC([O-])=O BVKZGUZCCUSVTD-UHFFFAOYSA-M 0.000 claims description 31
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 26
- 238000000034 method Methods 0.000 claims description 15
- 238000000502 dialysis Methods 0.000 claims description 10
- 238000012544 monitoring process Methods 0.000 claims description 7
- UIIMBOGNXHQVGW-UHFFFAOYSA-M Sodium bicarbonate Chemical compound [Na+].OC([O-])=O UIIMBOGNXHQVGW-UHFFFAOYSA-M 0.000 description 20
- QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 description 15
- 239000011734 sodium Substances 0.000 description 15
- QTBSBXVTEAMEQO-UHFFFAOYSA-M Acetate Chemical compound CC([O-])=O QTBSBXVTEAMEQO-UHFFFAOYSA-M 0.000 description 12
- 235000017557 sodium bicarbonate Nutrition 0.000 description 10
- 239000000243 solution Substances 0.000 description 9
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 8
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 description 7
- 239000008121 dextrose Substances 0.000 description 7
- 239000011777 magnesium Substances 0.000 description 6
- 239000000203 mixture Substances 0.000 description 5
- 239000000126 substance Substances 0.000 description 5
- TWRXJAOTZQYOKJ-UHFFFAOYSA-L Magnesium chloride Chemical compound [Mg+2].[Cl-].[Cl-] TWRXJAOTZQYOKJ-UHFFFAOYSA-L 0.000 description 4
- WCUXLLCKKVVCTQ-UHFFFAOYSA-M Potassium chloride Chemical compound [Cl-].[K+] WCUXLLCKKVVCTQ-UHFFFAOYSA-M 0.000 description 4
- 239000011780 sodium chloride Substances 0.000 description 4
- 235000002639 sodium chloride Nutrition 0.000 description 4
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 description 3
- 239000008280 blood Substances 0.000 description 3
- 210000004369 blood Anatomy 0.000 description 3
- 238000010586 diagram Methods 0.000 description 3
- 229910052708 sodium Inorganic materials 0.000 description 3
- UXVMQQNJUSDDNG-UHFFFAOYSA-L Calcium chloride Chemical compound [Cl-].[Cl-].[Ca+2] UXVMQQNJUSDDNG-UHFFFAOYSA-L 0.000 description 2
- WQZGKKKJIJFFOK-VFUOTHLCSA-N beta-D-glucose Chemical compound OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-VFUOTHLCSA-N 0.000 description 2
- 239000001110 calcium chloride Substances 0.000 description 2
- 229910001628 calcium chloride Inorganic materials 0.000 description 2
- 230000008859 change Effects 0.000 description 2
- 239000000470 constituent Substances 0.000 description 2
- AZDIXEXNLJMBJO-UHFFFAOYSA-L disodium;cyanoiminomethanedithiolate Chemical compound [Na+].[Na+].[S-]C([S-])=NC#N AZDIXEXNLJMBJO-UHFFFAOYSA-L 0.000 description 2
- 239000004615 ingredient Substances 0.000 description 2
- 150000002500 ions Chemical class 0.000 description 2
- 229910001629 magnesium chloride Inorganic materials 0.000 description 2
- 239000012528 membrane Substances 0.000 description 2
- 239000001103 potassium chloride Substances 0.000 description 2
- 235000011164 potassium chloride Nutrition 0.000 description 2
- 238000000108 ultra-filtration Methods 0.000 description 2
- VMHLLURERBWHNL-UHFFFAOYSA-M Sodium acetate Chemical compound [Na+].CC([O-])=O VMHLLURERBWHNL-UHFFFAOYSA-M 0.000 description 1
- 239000003929 acidic solution Substances 0.000 description 1
- 235000011148 calcium chloride Nutrition 0.000 description 1
- 238000006243 chemical reaction Methods 0.000 description 1
- 230000003907 kidney function Effects 0.000 description 1
- 235000011147 magnesium chloride Nutrition 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 238000005259 measurement Methods 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 230000004044 response Effects 0.000 description 1
- 239000001632 sodium acetate Substances 0.000 description 1
- 235000017281 sodium acetate Nutrition 0.000 description 1
- 229910000030 sodium bicarbonate Inorganic materials 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
- A61M1/16—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes
- A61M1/1654—Dialysates therefor
- A61M1/1656—Apparatus for preparing dialysates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
- A61M1/16—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes
- A61M1/1654—Dialysates therefor
- A61M1/1656—Apparatus for preparing dialysates
- A61M1/166—Heating
- A61M1/1664—Heating with temperature control
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
- A61M1/16—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes
- A61M1/1654—Dialysates therefor
- A61M1/1656—Apparatus for preparing dialysates
- A61M1/1666—Apparatus for preparing dialysates by dissolving solids
Landscapes
- Health & Medical Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Vascular Medicine (AREA)
- Engineering & Computer Science (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Emergency Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- External Artificial Organs (AREA)
- Investigating Or Analyzing Materials By The Use Of Electric Means (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US07/795,908 US6139754A (en) | 1991-11-15 | 1991-11-15 | Hemodialysis conductivity servo-proportioning system and method |
| PCT/US1992/009816 WO1993009822A1 (en) | 1991-11-15 | 1992-11-12 | Hemodialysis conductivity servo-proportioning system |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE69213713D1 DE69213713D1 (de) | 1996-10-17 |
| DE69213713T2 true DE69213713T2 (de) | 1997-03-06 |
Family
ID=25166752
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE69213713T Revoked DE69213713T2 (de) | 1991-11-15 | 1992-11-12 | Leitfaehigkeit-servodosierungsystem zur hemodialyse |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US6139754A (enExample) |
| EP (1) | EP0567633B1 (enExample) |
| JP (1) | JP3319756B2 (enExample) |
| KR (1) | KR100238612B1 (enExample) |
| AU (1) | AU3136093A (enExample) |
| CA (1) | CA2099765C (enExample) |
| DE (1) | DE69213713T2 (enExample) |
| ES (1) | ES2094382T3 (enExample) |
| TW (1) | TW224939B (enExample) |
| WO (1) | WO1993009822A1 (enExample) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE102015005142A1 (de) * | 2015-04-22 | 2016-10-27 | Fresenius Medical Care Deutschland Gmbh | Verfahren und Vorrichtung zur Herstellung einer medizinischen Lösung |
Families Citing this family (36)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5244568A (en) | 1991-11-15 | 1993-09-14 | Baxter International Inc. | Automated hemodialysis chemical treatment system with control valve and proportioning pumps |
| EP0763728A4 (en) * | 1995-03-29 | 1999-01-27 | Toa Electronics | METHOD FOR DETERMINING THE NON-ELECTROLYTE CONTENT IN ELECTROLYT SOLUTIONS AND METHOD AND DEVICE FOR THE PRODUCTION OF SOLUTIONS MIXED FROM ELECTROLYTE AND NON-ELECTROLYTE |
| US6582385B2 (en) * | 1998-02-19 | 2003-06-24 | Nstage Medical, Inc. | Hemofiltration system including ultrafiltrate purification and re-infusion system |
| DE19849787C1 (de) * | 1998-10-28 | 2000-02-24 | Fresenius Medical Care De Gmbh | Blutbehandlungsgerät |
| SE525132C2 (sv) * | 2001-11-23 | 2004-12-07 | Gambro Lundia Ab | Metod vid manövrering av dialysanordning |
| US7122210B2 (en) * | 2002-01-11 | 2006-10-17 | Baxter International Inc. | Bicarbonate-based solutions for dialysis therapies |
| AU2008201009B2 (en) * | 2002-01-11 | 2010-07-01 | Nikkiso Co., Ltd. | Bicarbonate-based solutions for dialysis therapies |
| US20030216677A1 (en) * | 2002-05-15 | 2003-11-20 | Li Pan | Biosensor for dialysis therapy |
| US7544301B2 (en) | 2004-08-19 | 2009-06-09 | Hhd Llc | Citrate-based dialysate chemical formulations |
| US7935070B2 (en) | 2005-01-28 | 2011-05-03 | Fresenius Medical Care North America | Systems and methods for dextrose containing peritoneal dialysis (PD) solutions with neutral pH and reduced glucose degradation product |
| JP2008540061A (ja) * | 2005-05-17 | 2008-11-20 | フレゼニウス・メデイカル・ケア・ホールデイングス・インコーポレーテツド | 血液透析の方法と装置 |
| US7815809B2 (en) * | 2005-12-13 | 2010-10-19 | Gambro Lundia Ab | Method for conductivity calculation in a treatment fluid upstream and downstream a filtration unit in apparatuses for the blood treatment |
| US8057679B2 (en) * | 2008-07-09 | 2011-11-15 | Baxter International Inc. | Dialysis system having trending and alert generation |
| JP5423318B2 (ja) | 2009-10-29 | 2014-02-19 | ニプロ株式会社 | 透析液の濃度監視装置およびその作動方法 |
| US8753515B2 (en) | 2009-12-05 | 2014-06-17 | Home Dialysis Plus, Ltd. | Dialysis system with ultrafiltration control |
| US8501009B2 (en) | 2010-06-07 | 2013-08-06 | State Of Oregon Acting By And Through The State Board Of Higher Education On Behalf Of Oregon State University | Fluid purification system |
| US9585810B2 (en) | 2010-10-14 | 2017-03-07 | Fresenius Medical Care Holdings, Inc. | Systems and methods for delivery of peritoneal dialysis (PD) solutions with integrated inter-chamber diffuser |
| DE102011008185A1 (de) * | 2011-01-10 | 2012-07-12 | Fresenius Medical Care Deutschland Gmbh | Herstellung von Individualkonzentrat |
| US9861733B2 (en) | 2012-03-23 | 2018-01-09 | Nxstage Medical Inc. | Peritoneal dialysis systems, devices, and methods |
| CN103619372A (zh) | 2011-03-23 | 2014-03-05 | 纳科斯达格医药股份有限公司 | 腹膜透析系统、装置和方法 |
| CA2851245C (en) | 2011-10-07 | 2019-11-26 | Home Dialysis Plus, Ltd. | Heat exchange fluid purification for dialysis system |
| JP5099464B1 (ja) * | 2011-12-29 | 2012-12-19 | 富田製薬株式会社 | 重炭酸イオン濃度可変型の透析液の調製装置及び調製方法、重炭酸イオン濃度可変型の透析剤、並びに重炭酸イオン濃度可変型の透析システム |
| WO2015168280A1 (en) | 2014-04-29 | 2015-11-05 | Outset Medical, Inc. | Dialysis system and methods |
| CA2985719C (en) | 2015-06-25 | 2024-03-26 | Gambro Lundia Ab | Medical device system and method having a distributed database |
| US10617809B2 (en) | 2015-12-29 | 2020-04-14 | Fresenius Medical Care Holdings, Inc. | Electrical sensor for fluids |
| US10406269B2 (en) | 2015-12-29 | 2019-09-10 | Fresenius Medical Care Holdings, Inc. | Electrical sensor for fluids |
| EP4039286B1 (en) | 2016-08-19 | 2025-07-23 | Outset Medical, Inc. | Peritoneal dialysis system and methods |
| CN110100283B (zh) | 2016-12-21 | 2023-07-04 | 甘布罗伦迪亚股份公司 | 包括具有支持外域的安全集群域的信息技术基础架构的医疗设备系统 |
| DE102017109127A1 (de) * | 2017-04-27 | 2018-10-31 | B. Braun Avitum Ag | Verfahren und Vorrichtung zur intermittierenden, pulsierenden Proportionierung einer Dialysierflüssigkeitsmischung |
| WO2018237375A1 (en) | 2017-06-24 | 2018-12-27 | Nxstage Medical, Inc. | Peritoneal dialysis fluid preparation and/or treatment devices methods and systems |
| JP6892602B2 (ja) * | 2017-08-10 | 2021-06-23 | 澁谷工業株式会社 | 透析液調製システムにおける成分監視方法 |
| DE102018103845A1 (de) * | 2018-02-21 | 2019-08-22 | Fresenius Medical Care Deutschland Gmbh | Modellierbasierte Mischung einer Dialysierflüssigkeit für ein Dialysegerät |
| EP3758771B1 (en) | 2018-02-28 | 2025-10-01 | NxStage Medical, Inc. | Fluid preparation methods |
| DE102018107627A1 (de) | 2018-03-29 | 2019-10-02 | Fresenius Medical Care Deutschland Gmbh | Dialysegerät und Verfahren zum Betreiben eines Dialysegerätes |
| US12201762B2 (en) | 2018-08-23 | 2025-01-21 | Outset Medical, Inc. | Dialysis system and methods |
| AU2020266584B2 (en) | 2019-04-30 | 2025-10-23 | Outset Medical, Inc. | Dialysis system and methods |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3847809A (en) * | 1972-07-03 | 1974-11-12 | David Kopf Syst | Proportioning system |
| US3992301A (en) * | 1973-11-19 | 1976-11-16 | Raypak, Inc. | Automatic flushing system for membrane separation machines such as reverse osmosis machines |
| SE401894B (sv) * | 1976-10-14 | 1978-06-05 | Gambro Ab | Dialyssystem |
| US4202760A (en) * | 1978-07-24 | 1980-05-13 | Cordis Dow Corp. | Apparatus and method for preparation of a hemodialysis solution optionally containing bicarbonate |
| US4399036A (en) * | 1979-06-14 | 1983-08-16 | Diachem, Inc. | Proportioning system for bicarbonate dialysate |
| US4601830A (en) * | 1979-11-19 | 1986-07-22 | The United States Of America As Represented By The Administrator Of Veteran Affairs | Method for dialysis |
| US4331540A (en) * | 1980-04-21 | 1982-05-25 | Baxter Travenol Laboratories, Inc. | Process for draining dialysate from artificial kidney |
| CA1183461A (en) * | 1981-05-01 | 1985-03-05 | Russell L. Jeffery | Dialysate preparation apparatus |
| DE3223051C2 (de) * | 1982-06-21 | 1984-09-13 | Fresenius AG, 6380 Bad Homburg | Dialysevorrichtung mit geregelter Dialysierlösung |
| DE3416057A1 (de) * | 1984-04-30 | 1985-10-31 | Fresenius AG, 6380 Bad Homburg | Haemodialysevorrichtung |
| US4739492A (en) * | 1985-02-21 | 1988-04-19 | Cochran Michael J | Dialysis machine which verifies operating parameters |
| US5091094A (en) * | 1985-06-24 | 1992-02-25 | Veech Richard L | Hemodialysis processes & hemodialysis solutions |
| US4789467A (en) * | 1986-04-30 | 1988-12-06 | Baxter Travenol Laboratories, Inc. | Automated disinfection system |
| US4857181A (en) * | 1986-10-30 | 1989-08-15 | Cobe Laboratories, Inc. | Control of cleaning of dialysate preparation apparatus |
| DE3639797C1 (en) * | 1986-11-21 | 1988-02-25 | Fresenius Ag | Method and device for monitoring the correct composition of dialysis solution, in particular for bicarbonate dialysis |
| US4828693A (en) * | 1987-09-22 | 1989-05-09 | Baxter Travenol Laboratories, Inc. | Water pressure regulator for hemodialysis apparatus |
| DE3734880C1 (de) * | 1987-10-15 | 1989-03-23 | Fresenius Ag | Vorrichtung fuer die Haemodialyse mit Schutzsystem gegen falsche Zusammensetzung der Dialysierfluessigkeit |
| US5094748A (en) * | 1990-02-06 | 1992-03-10 | Portillo Jr Luis C | Centralized bicarbonate concentrate distribution system |
| SE467816B (sv) * | 1990-02-19 | 1992-09-21 | Gambro Ab | System foer beredning av en vaetska avsedd foer medicinskt bruk |
-
1991
- 1991-11-15 US US07/795,908 patent/US6139754A/en not_active Expired - Lifetime
-
1992
- 1992-11-12 AU AU31360/93A patent/AU3136093A/en not_active Abandoned
- 1992-11-12 ES ES92925219T patent/ES2094382T3/es not_active Expired - Lifetime
- 1992-11-12 KR KR1019930702110A patent/KR100238612B1/ko not_active Expired - Fee Related
- 1992-11-12 CA CA002099765A patent/CA2099765C/en not_active Expired - Fee Related
- 1992-11-12 WO PCT/US1992/009816 patent/WO1993009822A1/en not_active Ceased
- 1992-11-12 DE DE69213713T patent/DE69213713T2/de not_active Revoked
- 1992-11-12 EP EP92925219A patent/EP0567633B1/en not_active Revoked
- 1992-11-12 JP JP50942793A patent/JP3319756B2/ja not_active Expired - Fee Related
- 1992-11-16 TW TW081109146A patent/TW224939B/zh not_active IP Right Cessation
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE102015005142A1 (de) * | 2015-04-22 | 2016-10-27 | Fresenius Medical Care Deutschland Gmbh | Verfahren und Vorrichtung zur Herstellung einer medizinischen Lösung |
| US10940255B2 (en) | 2015-04-22 | 2021-03-09 | Fresenius Medical Care Deutschland Gmbh | Method and apparatus for preparing a medical solution |
Also Published As
| Publication number | Publication date |
|---|---|
| TW224939B (enExample) | 1994-06-11 |
| WO1993009822A1 (en) | 1993-05-27 |
| KR930703031A (ko) | 1993-11-29 |
| ES2094382T3 (es) | 1997-01-16 |
| JPH06504708A (ja) | 1994-06-02 |
| AU3136093A (en) | 1993-06-15 |
| US6139754A (en) | 2000-10-31 |
| EP0567633B1 (en) | 1996-09-11 |
| CA2099765C (en) | 2003-01-07 |
| EP0567633A1 (en) | 1993-11-03 |
| CA2099765A1 (en) | 1993-05-16 |
| DE69213713D1 (de) | 1996-10-17 |
| KR100238612B1 (ko) | 2000-01-15 |
| JP3319756B2 (ja) | 2002-09-03 |
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