DE69208636T2 - Verfahren zur herstellung von zidovudine - Google Patents

Verfahren zur herstellung von zidovudine

Info

Publication number
DE69208636T2
DE69208636T2 DE69208636T DE69208636T DE69208636T2 DE 69208636 T2 DE69208636 T2 DE 69208636T2 DE 69208636 T DE69208636 T DE 69208636T DE 69208636 T DE69208636 T DE 69208636T DE 69208636 T2 DE69208636 T2 DE 69208636T2
Authority
DE
Germany
Prior art keywords
zidovudine
producing
azt
complex
deoxythymidine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69208636T
Other languages
English (en)
Other versions
DE69208636D1 (de
Inventor
Bruno Radatus
Khashayar Karimian
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Apotex Pharmachem Inc
Original Assignee
ACIC (CANADA) Inc BRANDFORD ONTARIO CA
Acic Canada Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ACIC (CANADA) Inc BRANDFORD ONTARIO CA, Acic Canada Inc filed Critical ACIC (CANADA) Inc BRANDFORD ONTARIO CA
Application granted granted Critical
Publication of DE69208636D1 publication Critical patent/DE69208636D1/de
Publication of DE69208636T2 publication Critical patent/DE69208636T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06—Pyrimidine radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DE69208636T 1991-06-21 1992-06-22 Verfahren zur herstellung von zidovudine Expired - Fee Related DE69208636T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US71783191A 1991-06-21 1991-06-21
PCT/CA1992/000269 WO1993000351A1 (en) 1991-06-21 1992-06-22 Novel anti-viral compounds and processes for production of anti-viral compounds

Publications (2)

Publication Number Publication Date
DE69208636D1 DE69208636D1 (de) 1996-04-04
DE69208636T2 true DE69208636T2 (de) 1996-07-11

Family

ID=24883679

Family Applications (2)

Application Number Title Priority Date Filing Date
DE69208636T Expired - Fee Related DE69208636T2 (de) 1991-06-21 1992-06-22 Verfahren zur herstellung von zidovudine
DE0550714T Pending DE550714T1 (de) 1991-06-21 1992-06-22 Antiviralverbindungen und Ihrer Verfahren zur Herstellung.

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE0550714T Pending DE550714T1 (de) 1991-06-21 1992-06-22 Antiviralverbindungen und Ihrer Verfahren zur Herstellung.

Country Status (9)

Country Link
US (2) US5387677A (de)
EP (1) EP0550714B1 (de)
AT (1) ATE134643T1 (de)
AU (1) AU2181592A (de)
CA (1) CA2090026C (de)
DE (2) DE69208636T2 (de)
ES (1) ES2085023T3 (de)
HU (1) HUT63852A (de)
WO (1) WO1993000351A1 (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2111970C1 (ru) * 1996-06-25 1998-05-27 Иван Игоревич Федоров 3'-оксимино-2',3'-дидезоксинуклеозиды
CN102731600B (zh) * 2012-03-13 2013-06-19 绿洲生物技术（南通）有限公司 齐多夫定及其中间体的制备方法

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4211773A (en) * 1978-10-02 1980-07-08 Sloan Kettering Institute For Cancer Research 5-Substituted 1-(2'-Deoxy-2'-substituted-β-D-arabinofuranosyl)pyrimidine nucleosides
US4874751A (en) * 1985-03-16 1989-10-17 Burroughs Wellcome Co. Antibacterial treatment
US4724232A (en) * 1985-03-16 1988-02-09 Burroughs Wellcome Co. Treatment of human viral infections
US4818750A (en) * 1985-09-17 1989-04-04 Burroughs Wellcome Co. Treatment of human viral infections
US4857511A (en) * 1985-09-17 1989-08-15 Burroughs Wellcome Co. Treatment of human viral infections
GB2181128A (en) * 1985-09-17 1987-04-15 Wellcome Found 3'-azidonucleosides
US4847244A (en) * 1985-09-17 1989-07-11 Burroughs Wellcome Co. Treatment of human viral infections
GB8707421D0 (en) * 1987-03-27 1987-04-29 Wellcome Found Pharmaceutical formulations
US4837311A (en) * 1987-06-22 1989-06-06 Hoffman-La Roche Inc. Anti-retroviral compounds
US4904770A (en) * 1988-03-24 1990-02-27 Bristol-Myers Company Production of 2',3'-dideoxy-2',3'-didehydronucleosides
US4921950A (en) * 1988-06-09 1990-05-01 Burroughs Wellcome Co. Preparation of 3'azido-3-'-deoxythymidine
US4916218A (en) * 1988-06-09 1990-04-10 Almond Merrick R 1-(β-D-xylofuranosyl)thymine derivatives

Also Published As

Publication number Publication date
ES2085023T3 (es) 1996-05-16
ATE134643T1 (de) 1996-03-15
US5519129A (en) 1996-05-21
EP0550714B1 (de) 1996-02-28
US5387677A (en) 1995-02-07
DE69208636D1 (de) 1996-04-04
CA2090026A1 (en) 1992-12-22
WO1993000351A1 (en) 1993-01-07
HU9300462D0 (en) 1993-05-28
HUT63852A (en) 1993-10-28
DE550714T1 (de) 1995-06-14
CA2090026C (en) 1995-09-19
EP0550714A1 (de) 1993-07-14
AU2181592A (en) 1993-01-25

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: BRANTFORD CHEMICALS INC., BRANTFORD, ONTARIO, CA

8339 Ceased/non-payment of the annual fee