DE69130171D1 - Bestimmung von analyten durch übertragung von fluoreszenzenergie - Google Patents

Bestimmung von analyten durch übertragung von fluoreszenzenergie

Info

Publication number
DE69130171D1
DE69130171D1 DE69130171T DE69130171T DE69130171D1 DE 69130171 D1 DE69130171 D1 DE 69130171D1 DE 69130171 T DE69130171 T DE 69130171T DE 69130171 T DE69130171 T DE 69130171T DE 69130171 D1 DE69130171 D1 DE 69130171D1
Authority
DE
Germany
Prior art keywords
concentration
fluorochromes
fluorochrome
camp
transfer
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69130171T
Other languages
English (en)
Other versions
DE69130171T2 (de
Inventor
Roger Tsien
Susan Taylor
Stephen Adams
Ying Ji
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of California
Original Assignee
University of California
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of California filed Critical University of California
Publication of DE69130171D1 publication Critical patent/DE69130171D1/de
Application granted granted Critical
Publication of DE69130171T2 publication Critical patent/DE69130171T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/536—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
    • G01N33/542—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with steric inhibition or signal modification, e.g. fluorescent quenching
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/582—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with fluorescent label
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/80—Fluorescent dyes, e.g. rhodamine

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Pathology (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Analysing Materials By The Use Of Radiation (AREA)
  • Holo Graphy (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
DE69130171T 1990-07-02 1991-07-01 Bestimmung von analyten durch übertragung von fluoreszenzenergie Expired - Fee Related DE69130171T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US54799090A 1990-07-02 1990-07-02
PCT/US1991/004676 WO1992000388A1 (en) 1990-07-02 1991-07-01 Detection of analytes using fluorescent energy transfer

Publications (2)

Publication Number Publication Date
DE69130171D1 true DE69130171D1 (de) 1998-10-15
DE69130171T2 DE69130171T2 (de) 1999-06-24

Family

ID=24186980

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69130171T Expired - Fee Related DE69130171T2 (de) 1990-07-02 1991-07-01 Bestimmung von analyten durch übertragung von fluoreszenzenergie

Country Status (7)

Country Link
US (1) US5439797A (de)
EP (1) EP0537270B1 (de)
JP (1) JP3208486B2 (de)
AT (1) ATE170980T1 (de)
DE (1) DE69130171T2 (de)
DK (1) DK0537270T3 (de)
WO (1) WO1992000388A1 (de)

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US6358684B1 (en) 1999-08-27 2002-03-19 Pe Corporation UV excitable fluorescent energy transfer dyes
US20030190644A1 (en) 1999-10-13 2003-10-09 Andreas Braun Methods for generating databases and databases for identifying polymorphic genetic markers
EP1305412A2 (de) 1999-10-14 2003-05-02 Clontech Laboratories Inc. Chromo/fluoroproteine aus anthozoa und verwendung der gleichen
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US7109315B2 (en) * 2000-03-15 2006-09-19 Bruce J. Bryan Renilla reniformis fluorescent proteins, nucleic acids encoding the fluorescent proteins and the use thereof in diagnostics, high throughput screening and novelty items
US6808874B2 (en) 2000-06-13 2004-10-26 Cyclacel Ltd. Methods of monitoring enzyme activity
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US20030044847A1 (en) * 2001-05-15 2003-03-06 Sidney Pestka Methods for anlyzing interactions between proteins in live and intact cells
JP3829252B2 (ja) * 2001-06-08 2006-10-04 独立行政法人理化学研究所 蛍光蛋白質
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US7491545B2 (en) * 2002-10-01 2009-02-17 Richard Thompson Excitation ratiometric fluoroscent biosensor for zinc ion at picomolar levels
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US9068234B2 (en) * 2003-01-21 2015-06-30 Ptc Therapeutics, Inc. Methods and agents for screening for compounds capable of modulating gene expression
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US8426194B2 (en) 2003-01-21 2013-04-23 Ptc Therapeutics, Inc. Methods and agents for screening for compounds capable of modulating VEGF expression
US20070020630A1 (en) * 2003-03-27 2007-01-25 Trotta Christopher R Methods of identifying compounds that target trna splicing endonuclease and uses of said compounds as anti-proliferative agents
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Also Published As

Publication number Publication date
WO1992000388A1 (en) 1992-01-09
JPH05508772A (ja) 1993-12-09
EP0537270B1 (de) 1998-09-09
DK0537270T3 (da) 1999-06-07
EP0537270A4 (en) 1996-07-24
JP3208486B2 (ja) 2001-09-10
DE69130171T2 (de) 1999-06-24
ATE170980T1 (de) 1998-09-15
US5439797A (en) 1995-08-08
EP0537270A1 (de) 1993-04-21

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Legal Events

Date Code Title Description
8332 No legal effect for de
8370 Indication related to discontinuation of the patent is to be deleted
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee