DE69130117D1 - Methode und Zusammensetzungen zur Behandlung von bösartigen Entartungen, die in Zusammenhang mit einer Proteinkinase stehen - Google Patents

Methode und Zusammensetzungen zur Behandlung von bösartigen Entartungen, die in Zusammenhang mit einer Proteinkinase stehen

Info

Publication number
DE69130117D1
DE69130117D1 DE69130117T DE69130117T DE69130117D1 DE 69130117 D1 DE69130117 D1 DE 69130117D1 DE 69130117 T DE69130117 T DE 69130117T DE 69130117 T DE69130117 T DE 69130117T DE 69130117 D1 DE69130117 D1 DE 69130117D1
Authority
DE
Germany
Prior art keywords
compositions
treatment
protein kinase
malignancies
degeneration associated
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69130117T
Other languages
English (en)
Inventor
Edmond H Dr Fischer
Edwin G Dr Krebs
Deborah Dr Cool
Nick Dr Tonks
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Washington Research Foundation
Original Assignee
Washington Research Foundation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Washington Research Foundation filed Critical Washington Research Foundation
Application granted granted Critical
Publication of DE69130117D1 publication Critical patent/DE69130117D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Bending Of Plates, Rods, And Pipes (AREA)
  • Manufacture Of Motors, Generators (AREA)
DE69130117T 1990-03-14 1991-03-14 Methode und Zusammensetzungen zur Behandlung von bösartigen Entartungen, die in Zusammenhang mit einer Proteinkinase stehen Expired - Lifetime DE69130117D1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US49403690A 1990-03-14 1990-03-14

Publications (1)

Publication Number Publication Date
DE69130117D1 true DE69130117D1 (de) 1998-10-08

Family

ID=23962758

Family Applications (2)

Application Number Title Priority Date Filing Date
DE69110034T Expired - Fee Related DE69110034T2 (de) 1990-03-14 1991-03-14 Methoden und zusammensetzungen zur behandlung von bösartigen entartungen, die in zusammenhang mit einer proteinkinase stehen.
DE69130117T Expired - Lifetime DE69130117D1 (de) 1990-03-14 1991-03-14 Methode und Zusammensetzungen zur Behandlung von bösartigen Entartungen, die in Zusammenhang mit einer Proteinkinase stehen

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DE69110034T Expired - Fee Related DE69110034T2 (de) 1990-03-14 1991-03-14 Methoden und zusammensetzungen zur behandlung von bösartigen entartungen, die in zusammenhang mit einer proteinkinase stehen.

Country Status (9)

Country Link
EP (2) EP0627489B1 (de)
JP (1) JPH05505527A (de)
AT (2) ATE170561T1 (de)
CA (1) CA2078010A1 (de)
DE (2) DE69110034T2 (de)
DK (1) DK0520029T3 (de)
ES (1) ES2073165T3 (de)
GR (1) GR3017164T3 (de)
WO (1) WO1991013989A1 (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE911115A1 (en) * 1990-04-10 1991-10-23 Canji Inc Gene therapy for cell proliferative diseases
US5536636A (en) * 1991-06-26 1996-07-16 Beth Israel Hospital Methods for identifying a tyrosine phosphatase abnormality associated with neoplastic disease
GB9214754D0 (en) * 1992-07-10 1992-08-19 Univ Singapore Tumour treatment
MX9304769A (es) * 1992-08-05 1994-05-31 Max Planck Gesellschaft Subfamilia ptp-d de fosfatasas de la proteina tirosina.
AU6688696A (en) * 1995-08-10 1997-03-05 Incyte Pharmaceuticals, Inc. Non-receptor type human protein tyrosine phosphatase
US6238902B1 (en) 1996-03-22 2001-05-29 Genentech, Inc. Protein tyrosine phosphatases
WO1997035019A1 (en) * 1996-03-22 1997-09-25 Genentech, Inc. Protein tyrosine phosphatases of hematopoietic cells
US6248327B1 (en) 1998-09-11 2001-06-19 Vanderbilt University Modulation of endothelial cell surface receptor activity in the regulation of angiogenesis
US7176289B1 (en) 1998-09-11 2007-02-13 Vanderbilt University Modulation of endothelial cell surface receptor activity in the regulation of angiogenesis
US6485974B1 (en) 2001-05-18 2002-11-26 Isis Pharmaceuticals, Inc. Antisense modulation of PTPN2 expression

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4710469A (en) * 1986-05-02 1987-12-01 Merck & Co., Inc. Novel phosphotyrosyl protein phosphatase

Also Published As

Publication number Publication date
DE69110034T2 (de) 1995-10-05
EP0520029A1 (de) 1992-12-30
DE69110034D1 (de) 1995-06-29
DK0520029T3 (da) 1995-10-16
WO1991013989A1 (en) 1991-09-19
EP0627489B1 (de) 1998-09-02
ATE170561T1 (de) 1998-09-15
ES2073165T3 (es) 1995-08-01
ATE123064T1 (de) 1995-06-15
GR3017164T3 (en) 1995-11-30
EP0520029B1 (de) 1995-05-24
CA2078010A1 (en) 1992-09-15
EP0627489A1 (de) 1994-12-07
JPH05505527A (ja) 1993-08-19

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Legal Events

Date Code Title Description
8332 No legal effect for de