GR3017164T3 - Methods and compositions for the treatment of malignancies in which a protein kinase is associated. - Google Patents

Methods and compositions for the treatment of malignancies in which a protein kinase is associated.

Info

Publication number
GR3017164T3
GR3017164T3 GR950402274T GR950402274T GR3017164T3 GR 3017164 T3 GR3017164 T3 GR 3017164T3 GR 950402274 T GR950402274 T GR 950402274T GR 950402274 T GR950402274 T GR 950402274T GR 3017164 T3 GR3017164 T3 GR 3017164T3
Authority
GR
Greece
Prior art keywords
malignancies
compositions
treatment
methods
protein kinase
Prior art date
Application number
GR950402274T
Other languages
English (en)
Inventor
Edmond H Fischer
Edwin G Krebs
Nicholas K Tonks
Deborah E Cool
Original Assignee
Washington Res Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Washington Res Found filed Critical Washington Res Found
Publication of GR3017164T3 publication Critical patent/GR3017164T3/el

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10Transferases (2.)
    • C12N9/12Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/16Hydrolases (3) acting on ester bonds (3.1)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Bending Of Plates, Rods, And Pipes (AREA)
  • Manufacture Of Motors, Generators (AREA)
GR950402274T 1990-03-14 1995-08-23 Methods and compositions for the treatment of malignancies in which a protein kinase is associated. GR3017164T3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US49403690A 1990-03-14 1990-03-14
PCT/US1991/001748 WO1991013989A1 (en) 1990-03-14 1991-03-14 Methods and compositions for the treatment of malignancies in which a protein kinase is associated

Publications (1)

Publication Number Publication Date
GR3017164T3 true GR3017164T3 (en) 1995-11-30

Family

ID=23962758

Family Applications (1)

Application Number Title Priority Date Filing Date
GR950402274T GR3017164T3 (en) 1990-03-14 1995-08-23 Methods and compositions for the treatment of malignancies in which a protein kinase is associated.

Country Status (9)

Country Link
EP (2) EP0627489B1 (el)
JP (1) JPH05505527A (el)
AT (2) ATE170561T1 (el)
CA (1) CA2078010A1 (el)
DE (2) DE69110034T2 (el)
DK (1) DK0520029T3 (el)
ES (1) ES2073165T3 (el)
GR (1) GR3017164T3 (el)
WO (1) WO1991013989A1 (el)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE911115A1 (en) * 1990-04-10 1991-10-23 Canji Inc Gene therapy for cell proliferative diseases
US5536636A (en) * 1991-06-26 1996-07-16 Beth Israel Hospital Methods for identifying a tyrosine phosphatase abnormality associated with neoplastic disease
GB9214754D0 (en) * 1992-07-10 1992-08-19 Univ Singapore Tumour treatment
MX9304769A (es) * 1992-08-05 1994-05-31 Max Planck Gesellschaft Subfamilia ptp-d de fosfatasas de la proteina tirosina.
AU6688696A (en) * 1995-08-10 1997-03-05 Incyte Pharmaceuticals, Inc. Non-receptor type human protein tyrosine phosphatase
US6238902B1 (en) 1996-03-22 2001-05-29 Genentech, Inc. Protein tyrosine phosphatases
WO1997035019A1 (en) * 1996-03-22 1997-09-25 Genentech, Inc. Protein tyrosine phosphatases of hematopoietic cells
US6248327B1 (en) 1998-09-11 2001-06-19 Vanderbilt University Modulation of endothelial cell surface receptor activity in the regulation of angiogenesis
US7176289B1 (en) 1998-09-11 2007-02-13 Vanderbilt University Modulation of endothelial cell surface receptor activity in the regulation of angiogenesis
US6485974B1 (en) 2001-05-18 2002-11-26 Isis Pharmaceuticals, Inc. Antisense modulation of PTPN2 expression

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4710469A (en) * 1986-05-02 1987-12-01 Merck & Co., Inc. Novel phosphotyrosyl protein phosphatase

Also Published As

Publication number Publication date
DE69110034T2 (de) 1995-10-05
EP0520029A1 (en) 1992-12-30
DE69110034D1 (de) 1995-06-29
DK0520029T3 (da) 1995-10-16
WO1991013989A1 (en) 1991-09-19
EP0627489B1 (en) 1998-09-02
ATE170561T1 (de) 1998-09-15
DE69130117D1 (de) 1998-10-08
ES2073165T3 (es) 1995-08-01
ATE123064T1 (de) 1995-06-15
EP0520029B1 (en) 1995-05-24
CA2078010A1 (en) 1992-09-15
EP0627489A1 (en) 1994-12-07
JPH05505527A (ja) 1993-08-19

Similar Documents

Publication Publication Date Title
ES2170366T3 (es) Secuencia de adn aislada del gen brca1 y su utilizacion en terapia antitumoral.
DE69333766D1 (de) Herstellung von phytat-degradierenden enzymen in trichoderma
EP1757689A3 (en) Mammalian apoptosis inhibitor protein gene family, primers, probes and detection methods
DK1005540T3 (da) IKK-beta-proteiner, nukleinsyrer og fremgangsmåder
DK1032668T3 (da) Fibroblast vækstfaktor 19
WO2001000669A3 (en) A bap28 gene and protein
NZ503100A (en) 2-deoxyglucose-6-phosphate (2-DOG-6-P) phosphatase DNA sequences as selection markers in plants
DK0917571T3 (da) Hidtil ukendt agoutirelateret gen
GR3017164T3 (en) Methods and compositions for the treatment of malignancies in which a protein kinase is associated.
ATE391175T1 (de) Multidrug resistenz gen
HU9601448D0 (en) Novel apoptosis-modulating proteins, dna encoding the proteins and methods of use thereof
NZ242124A (en) Dna encoding an enzyme having arabinan-degrading activity
CA2294566A1 (en) Ikk-.alpha. proteins, nucleic acids and methods
DE69928395D1 (de) Cyclin-e2 proteine und dafür kodierende gene
SE7806087L (sv) Forfarande for rening av nukleotidsekvenser lempliga som syntetiseringsmall i bakterier, mikroorganism innefattande dylik nukleotidsekvens samt rekombinant dna-overforingsvektor innefattande dylik nukleotid
WO1994028129A3 (en) Tumour metastasis gene
EP0676413A3 (en) Interferon alpha / beta binding protein, its production and application.
HK1118861A1 (en) Genes differentially expressed in breast cancer
CA2347371A1 (en) HEMATOPOIETIC REGULATION FACTORS AND METHODS OF USE
ATE327334T1 (de) Atp- und nukleinsäure-bindendes protein mit helikase- und atpase eigenschaften
EA199900339A1 (ru) Ген роста человека и область гена, ответственная за низкий рост
DE59902472D1 (de) Zusammensetzung zur induktion einer tumorspezifischen immunantwort, verfahren zu deren herstellung sowie verwendung der zusammensetzung zur behandlung von neoplasien
ATE391176T1 (de) Neues gen mit induzierter expression in menschlichen metastatischen tumorzellen
ATE84315T1 (de) Rekombinante dna zur reprimierbaren und induzierbaren expression von fremdgenen.