ES2073165T3 - Metodos y composiciones para el tratamiento de enfermedades malignas a las que esta asociada una proteina quinasa. - Google Patents
Metodos y composiciones para el tratamiento de enfermedades malignas a las que esta asociada una proteina quinasa.Info
- Publication number
- ES2073165T3 ES2073165T3 ES91906924T ES91906924T ES2073165T3 ES 2073165 T3 ES2073165 T3 ES 2073165T3 ES 91906924 T ES91906924 T ES 91906924T ES 91906924 T ES91906924 T ES 91906924T ES 2073165 T3 ES2073165 T3 ES 2073165T3
- Authority
- ES
- Spain
- Prior art keywords
- compositions
- treatment
- methods
- protein kinase
- malignant diseases
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Biomedical Technology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Enzymes And Modification Thereof (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
SE PRESENTAN METODOS Y COMPUESTOS PARA EL TRATAMIENTO DE ENFERMEDADES EN LAS CUALES ESTE ASOCIADA UNA QUINASA DE TIROSINA. LAS ENFERMEDADES PUEDEN TRATARSE CON UN VEHICULO DE TRANFERENCIA DE GEN CAPAZ DE INFECTAR LAS CELULAS MALIGNAS, EN EL QUE EL VEHICULO DE TRANSFERENCIA DEL GEN SOPORTA UNA CONSTRUCCION DE DNA QUE COMPRENDE UNA SECUENCIA DE DNA QUE CODIFICA UNA FOSFATASA DE TIROSINA DE LA PROTEINA (PTPASA). SECUENCIAS DE DNA ADECUADAS INCLUYEN AQUELLAS QUE CODIFICAN LAS PTPASAS DE TIPO SALVAJE, O TRUNCADAS EN EL TERMINO CARBOXIL.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US49403690A | 1990-03-14 | 1990-03-14 |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2073165T3 true ES2073165T3 (es) | 1995-08-01 |
Family
ID=23962758
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES91906924T Expired - Lifetime ES2073165T3 (es) | 1990-03-14 | 1991-03-14 | Metodos y composiciones para el tratamiento de enfermedades malignas a las que esta asociada una proteina quinasa. |
Country Status (9)
Country | Link |
---|---|
EP (2) | EP0627489B1 (es) |
JP (1) | JPH05505527A (es) |
AT (2) | ATE170561T1 (es) |
CA (1) | CA2078010A1 (es) |
DE (2) | DE69130117D1 (es) |
DK (1) | DK0520029T3 (es) |
ES (1) | ES2073165T3 (es) |
GR (1) | GR3017164T3 (es) |
WO (1) | WO1991013989A1 (es) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IE911115A1 (en) * | 1990-04-10 | 1991-10-23 | Canji Inc | Gene therapy for cell proliferative diseases |
US5536636A (en) * | 1991-06-26 | 1996-07-16 | Beth Israel Hospital | Methods for identifying a tyrosine phosphatase abnormality associated with neoplastic disease |
GB9214754D0 (en) * | 1992-07-10 | 1992-08-19 | Univ Singapore | Tumour treatment |
MX9304769A (es) * | 1992-08-05 | 1994-05-31 | Max Planck Gesellschaft | Subfamilia ptp-d de fosfatasas de la proteina tirosina. |
WO1997006262A1 (en) * | 1995-08-10 | 1997-02-20 | Incyte Pharmaceuticals, Inc. | Non-receptor type human protein tyrosine phosphatase |
WO1997035019A1 (en) * | 1996-03-22 | 1997-09-25 | Genentech, Inc. | Protein tyrosine phosphatases of hematopoietic cells |
US6238902B1 (en) | 1996-03-22 | 2001-05-29 | Genentech, Inc. | Protein tyrosine phosphatases |
US6248327B1 (en) | 1998-09-11 | 2001-06-19 | Vanderbilt University | Modulation of endothelial cell surface receptor activity in the regulation of angiogenesis |
US7176289B1 (en) | 1998-09-11 | 2007-02-13 | Vanderbilt University | Modulation of endothelial cell surface receptor activity in the regulation of angiogenesis |
US6485974B1 (en) | 2001-05-18 | 2002-11-26 | Isis Pharmaceuticals, Inc. | Antisense modulation of PTPN2 expression |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4710469A (en) * | 1986-05-02 | 1987-12-01 | Merck & Co., Inc. | Novel phosphotyrosyl protein phosphatase |
-
1991
- 1991-03-14 ES ES91906924T patent/ES2073165T3/es not_active Expired - Lifetime
- 1991-03-14 DK DK91906924.5T patent/DK0520029T3/da active
- 1991-03-14 DE DE69130117T patent/DE69130117D1/de not_active Expired - Lifetime
- 1991-03-14 DE DE69110034T patent/DE69110034T2/de not_active Expired - Fee Related
- 1991-03-14 WO PCT/US1991/001748 patent/WO1991013989A1/en active IP Right Grant
- 1991-03-14 JP JP91507242A patent/JPH05505527A/ja active Pending
- 1991-03-14 AT AT94109172T patent/ATE170561T1/de not_active IP Right Cessation
- 1991-03-14 EP EP94109172A patent/EP0627489B1/en not_active Expired - Lifetime
- 1991-03-14 AT AT91906924T patent/ATE123064T1/de not_active IP Right Cessation
- 1991-03-14 EP EP91906924A patent/EP0520029B1/en not_active Expired - Lifetime
- 1991-03-14 CA CA002078010A patent/CA2078010A1/en not_active Abandoned
-
1995
- 1995-08-23 GR GR950402274T patent/GR3017164T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
DE69110034T2 (de) | 1995-10-05 |
EP0627489A1 (en) | 1994-12-07 |
DE69130117D1 (de) | 1998-10-08 |
WO1991013989A1 (en) | 1991-09-19 |
EP0520029A1 (en) | 1992-12-30 |
DK0520029T3 (da) | 1995-10-16 |
GR3017164T3 (en) | 1995-11-30 |
ATE170561T1 (de) | 1998-09-15 |
EP0627489B1 (en) | 1998-09-02 |
JPH05505527A (ja) | 1993-08-19 |
EP0520029B1 (en) | 1995-05-24 |
DE69110034D1 (de) | 1995-06-29 |
CA2078010A1 (en) | 1992-09-15 |
ATE123064T1 (de) | 1995-06-15 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
Kishi et al. | Human serum deoxyribonuclease I (DNase I) polymorphism: pattern similarities among isozymes from serum, urine, kidney, liver, and pancreas. | |
FI922812A (fi) | Stabil oeverfoering av dna till bakteriernas arvanslag. | |
BR8301918A (pt) | Proteina,sequencia de dna,veiculo de expressao replicavel,microorganismo ou cultura celular,plasmideo,composicao,cultura de celulas,utilizacao de tal proteina,processo de expressao,processo para producao de um veiculo de expressao e processo para preparacao de uma proteina uroquinase | |
DK1218509T3 (da) | Fibroblast vækstfaktorlignende polypeptider | |
ES8500322A1 (es) | Un metodo de modificar un virus para conferirle una nueva funcion biologica. | |
DK478786A (da) | Cystein-forarmede muteiner af biologisk aktive humantumornekrosefaktorproteiner | |
ES2073165T3 (es) | Metodos y composiciones para el tratamiento de enfermedades malignas a las que esta asociada una proteina quinasa. | |
DK494681A (da) | Femgangsmaade til fremstilling af interferoner | |
ATE310819T1 (de) | Säugetieren apoptosis inhibitorprotein genfamilie,primers, probes und verfahren zur nachweis | |
ATE269402T1 (de) | Ikk-beta proteine, nukleinsäuren und verfahren | |
FI831818L (fi) | Mikrobiologiskt framstaellda - och -interferoner, dessa interferoner kodande dna-sekvenser, dennagenetiska information innehaollande mikroorganismer och deras framstaellningsfoerfarande | |
DE3587875T3 (de) | Rekombinantverfahren zur herstellung von serinproteaseinhibitoren, sowie dns-sequenzen dazu. | |
Kim et al. | Purification and partial characterization of (6‐4) photoproduct DNA photolyase from Xenopus laevis | |
SE8801701D0 (sv) | Production technology based on enzymic method | |
DE3688324D1 (de) | Dna-sequenzen, die fuer proteine mit der biologischen aktivitaet der husi-typi-inhibitoren codieren, gentechnologische verfahren zur herstellung dieser proteine und diese proteine enthaltende arzneimittel. | |
BR9815602A (pt) | Composição e processo para induzir uma respostaem células sensìveis de um animal para tratar umcancer | |
BR9712793A (pt) | Fatores homólogos (fhfs) ao fator do desenvolvimento de fibroblasto e métodos de uso | |
SE7806087L (sv) | Forfarande for rening av nukleotidsekvenser lempliga som syntetiseringsmall i bakterier, mikroorganism innefattande dylik nukleotidsekvens samt rekombinant dna-overforingsvektor innefattande dylik nukleotid | |
DE3782560T2 (de) | Hefestaemme zur expression fremder gene. | |
DE69721484D1 (de) | Nukleosidderivative in kombinationspräparaten zur behandlung von hsv krankheiten | |
Geithe et al. | Isolation of a homogeneous morphogenetic factor, inducing mesoderm and endoderm derived tissues in Triturus ectoderm | |
FI950516A (fi) | Interferoni-alfa/beta-sitojaproteiini, sen valmistus ja käyttö | |
ATE403716T1 (de) | Nukleinsäure und korrespondierendes protein 85p1b3, nützlich zur behandlung und detektion von krebserkrankungen | |
PT778347E (pt) | Proteina ligante a atp e acidos nucleicos com propriedade de helicase e de atpase | |
CA2347371A1 (en) | HEMATOPOIETIC REGULATION FACTORS AND METHODS OF USE |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG2A | Definitive protection |
Ref document number: 520029 Country of ref document: ES |