MX9304769A - Subfamilia ptp-d de fosfatasas de la proteina tirosina. - Google Patents

Subfamilia ptp-d de fosfatasas de la proteina tirosina.

Info

Publication number
MX9304769A
MX9304769A MX9304769A MX9304769A MX9304769A MX 9304769 A MX9304769 A MX 9304769A MX 9304769 A MX9304769 A MX 9304769A MX 9304769 A MX9304769 A MX 9304769A MX 9304769 A MX9304769 A MX 9304769A
Authority
MX
Mexico
Prior art keywords
ptp
protein
subfamily
thyrosine
protein phosphatases
Prior art date
Application number
MX9304769A
Other languages
English (en)
Inventor
Axel Ullrich
Niels Peter Hundahl Moller
Karin Bach Moller
Original Assignee
Max Planck Gesellschaft
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Max Planck Gesellschaft filed Critical Max Planck Gesellschaft
Publication of MX9304769A publication Critical patent/MX9304769A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
    • C12Q1/42—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase involving phosphatase
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/573—Immunoassay; Biospecific binding assay; Materials therefor for enzymes or isoenzymes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Abstract

Una nueva subfamilia (PTP-D) de las fosfatasas de la proteína tirosina se identifica. En esta familia se incluyen las proteínas PTP-D o glicoproteínas que tienen 1, 2 ó 3 cambios de aminoácidos identificadores en secuencias de consenso definidas con anterioridad en los dominios de la fosfatas catalítica de las fosfatasas de la proteína tirosina conocida. Las proteína PTP-D o glicoproteínas pueden producirse mediante recombinaciones. Se proporcionan anticuerpos a las proteínas PTP-D y glicoproteínas y códigos de construcción de ácido nucléico de las mismas, así como métodos para clasificar las moléculas que pueden unirse a las proteínas PTP-D o glicoproteínas e inhibir o estimular su actividad enzimática.
MX9304769A 1992-08-05 1992-08-05 Subfamilia ptp-d de fosfatasas de la proteina tirosina. MX9304769A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US92374092A 1992-08-05 1992-08-05

Publications (1)

Publication Number Publication Date
MX9304769A true MX9304769A (es) 1994-05-31

Family

ID=25449193

Family Applications (1)

Application Number Title Priority Date Filing Date
MX9304769A MX9304769A (es) 1992-08-05 1992-08-05 Subfamilia ptp-d de fosfatasas de la proteina tirosina.

Country Status (13)

Country Link
US (2) US5955592A (es)
EP (1) EP0654083B1 (es)
JP (1) JPH08501934A (es)
CN (1) CN1091139A (es)
AT (1) ATE237688T1 (es)
AU (1) AU4707793A (es)
CA (1) CA2141847A1 (es)
DE (1) DE69332883T2 (es)
DK (1) DK0654083T3 (es)
ES (1) ES2196010T3 (es)
MX (1) MX9304769A (es)
PT (1) PT654083E (es)
WO (1) WO1994003611A2 (es)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6258582B1 (en) 1998-09-30 2001-07-10 Millennium Pharmaceuticals, Inc. CSAPTP nucleic acid molecules and uses therefor
WO2000018890A2 (en) * 1998-09-30 2000-04-06 Millennium Pharmaceuticals, Inc. Protein phosphatase molecules and uses therefor
US6200807B1 (en) 1999-07-21 2001-03-13 Isis Pharmaceuticals Inc. Antisense inhibition of SHP-2 expression
US7313542B1 (en) * 1999-10-06 2007-12-25 Paymentech, L.P. System and method for processing retrieval requests
ES2245955T3 (es) * 1999-12-21 2006-02-01 Sugen, Inc. 7-aza-indolin-2-onas 4-sustituidas y su utilizacion como inhibidores de proteina-quinasa.
CA2397502A1 (en) * 2000-03-02 2001-09-07 Human Genome Sciences, Inc. Serine/threonine phosphatase polynucleotides, polypeptides, and antibodies
US20030224415A1 (en) * 2001-06-29 2003-12-04 Gala Design, Inc. Selection free growth of host cells containing multiple integrating vectors
JP4762478B2 (ja) * 2000-07-03 2011-08-31 キャタレント ファーマ ソリューションズ リミテッド ライアビリティ カンパニー 発現ベクター
US6852510B2 (en) * 2000-07-03 2005-02-08 Gala Design Inc Host cells containing multiple integrating vectors
WO2002079499A1 (en) 2001-04-02 2002-10-10 Wyeth Pd-1, a receptor for b7-4, and uses therefor
CA2495529C (en) * 2001-10-01 2009-05-19 Mount Sinai School Of Medicine Of New York University Noonan syndrome gene
US7384738B2 (en) * 2002-03-28 2008-06-10 Bremel Robert D Retrovirus-based genomic screening
US20040038304A1 (en) * 2002-03-28 2004-02-26 Gala Design, Inc. Antibody libraries
US20050221429A1 (en) * 2004-01-16 2005-10-06 Cardinal Health Pts, Llc Host cells containing multiple integrating vectors comprising an amplifiable marker
WO2006071451A2 (en) * 2004-12-03 2006-07-06 The Regents Of The University Of California Compounds that prevent macrophage apoptosis and uses thereof
WO2012000976A1 (en) * 2010-07-02 2012-01-05 Topogen Inc. Method for diagnosis of bladder cancer and related kits
WO2014022759A1 (en) 2012-08-03 2014-02-06 Dana-Farber Cancer Institute, Inc. Agents that modulate immune cell activation and methods of use thereof
CN108350030B (zh) * 2015-09-10 2022-12-13 汉阳大学校产学协力团 皮肤可渗透肽及其使用方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2054725A1 (en) * 1990-03-02 1991-09-03 Arthur M. Bruskin Ptpase vectors, diagnostics, therapeutics and uses thereof
ATE123064T1 (de) * 1990-03-14 1995-06-15 Washington Res Found Methoden und zusammensetzungen zur behandlung von bösartigen entartungen, die in zusammenhang mit einer proteinkinase stehen.
AU662296B2 (en) * 1990-07-11 1995-08-31 New York University Novel receptor-type phosphotyrosine phosphatase

Also Published As

Publication number Publication date
ES2196010T3 (es) 2003-12-16
WO1994003611A2 (en) 1994-02-17
DE69332883T2 (de) 2004-01-22
EP0654083B1 (en) 2003-04-16
EP0654083A1 (en) 1995-05-24
US5831009A (en) 1998-11-03
PT654083E (pt) 2003-08-29
CA2141847A1 (en) 1994-02-17
ATE237688T1 (de) 2003-05-15
CN1091139A (zh) 1994-08-24
US5955592A (en) 1999-09-21
DE69332883D1 (de) 2003-05-22
DK0654083T3 (da) 2003-08-11
WO1994003611A3 (en) 1994-03-31
JPH08501934A (ja) 1996-03-05
AU4707793A (en) 1994-03-03

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