ES2196010T3 - Spbfamilia ptp-d de proteinas tirosina fosfatasas. - Google Patents

Spbfamilia ptp-d de proteinas tirosina fosfatasas.

Info

Publication number
ES2196010T3
ES2196010T3 ES93917752T ES93917752T ES2196010T3 ES 2196010 T3 ES2196010 T3 ES 2196010T3 ES 93917752 T ES93917752 T ES 93917752T ES 93917752 T ES93917752 T ES 93917752T ES 2196010 T3 ES2196010 T3 ES 2196010T3
Authority
ES
Spain
Prior art keywords
ptp
protein
spbfamilia
thyrosine
phosphates
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES93917752T
Other languages
English (en)
Inventor
Axel Ullrich
Nils Peter Hundahl Moller
Karin Bach-Moller
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Max Planck Gesellschaft zur Foerderung der Wissenschaften eV
Original Assignee
Max Planck Gesellschaft zur Foerderung der Wissenschaften eV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Max Planck Gesellschaft zur Foerderung der Wissenschaften eV filed Critical Max Planck Gesellschaft zur Foerderung der Wissenschaften eV
Application granted granted Critical
Publication of ES2196010T3 publication Critical patent/ES2196010T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
    • C12Q1/42—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase involving phosphatase
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/573—Immunoassay; Biospecific binding assay; Materials therefor for enzymes or isoenzymes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • General Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Biophysics (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

SE PRESENTA UNA NUEVA SUBFAMILIA (PTP-D) DE FOSFATASAS DE TIROSINA DE LA PROTEINA. INCLUIDAS EN ESTA FAMILIA ESTAN LAS PROTEINAS PTP-D O LAS GLICOPROTEINAS QUE TIENEN UNO, DOS O TRES CAMBIOS IDENTIFICADOS EN EL AMINOACIDO EN SECUENCIAS DE CONSENSO PREVIAMENTE DEFINIDAS EN LOS DOMINANTES DE LA FOSFATASA CATALITICA DE LAS FOSFATASAS DE TIROSINA DE LA PROTEINA CONOCIDA. LAS PROTEINAS O LAS GLICOPROTEINAS PTP-D PUEDEN PRODUCIRSE MEDIANTE MEDIOS RECOMBINANTES. SE SUMINISTRAN ANTICUERPOS PARA LAS PROTEINAS O GLICOPROTEINAS PTP-D Y CONSTRUCCIONES DE ACIDO NUCLEICO QUE CODIFICAN LAS MISMAS Y METODOS PARA SELECCIONAR MOLECULAS QUE PUEDAN UNIRSE A LAS PROTEINAS O LAS GLICOPROTEINAS PTP-D E INHIBIR O ESTIMULAR SU ACTIVIDAD ENZIMATICA.
ES93917752T 1992-08-05 1993-08-05 Spbfamilia ptp-d de proteinas tirosina fosfatasas. Expired - Lifetime ES2196010T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US92374092A 1992-08-05 1992-08-05

Publications (1)

Publication Number Publication Date
ES2196010T3 true ES2196010T3 (es) 2003-12-16

Family

ID=25449193

Family Applications (1)

Application Number Title Priority Date Filing Date
ES93917752T Expired - Lifetime ES2196010T3 (es) 1992-08-05 1993-08-05 Spbfamilia ptp-d de proteinas tirosina fosfatasas.

Country Status (13)

Country Link
US (2) US5955592A (es)
EP (1) EP0654083B1 (es)
JP (1) JPH08501934A (es)
CN (1) CN1091139A (es)
AT (1) ATE237688T1 (es)
AU (1) AU4707793A (es)
CA (1) CA2141847A1 (es)
DE (1) DE69332883T2 (es)
DK (1) DK0654083T3 (es)
ES (1) ES2196010T3 (es)
MX (1) MX9304769A (es)
PT (1) PT654083E (es)
WO (1) WO1994003611A2 (es)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6258582B1 (en) 1998-09-30 2001-07-10 Millennium Pharmaceuticals, Inc. CSAPTP nucleic acid molecules and uses therefor
WO2000018890A2 (en) * 1998-09-30 2000-04-06 Millennium Pharmaceuticals, Inc. Protein phosphatase molecules and uses therefor
US6200807B1 (en) 1999-07-21 2001-03-13 Isis Pharmaceuticals Inc. Antisense inhibition of SHP-2 expression
US7313542B1 (en) * 1999-10-06 2007-12-25 Paymentech, L.P. System and method for processing retrieval requests
DE60021423T2 (de) * 1999-12-21 2006-04-13 Sugen, Inc., San Diego 4-substituierte 7-aza-indolin-2-one und ihre verwendung als proteinkinaseinhibitoren
JP2003525057A (ja) * 2000-03-02 2003-08-26 ヒューマン ジノーム サイエンシーズ， インコーポレイテッド セリン／トレオニンホスファターゼのポリヌクレオチド、ポリペプチド、および抗体
US20030224415A1 (en) * 2001-06-29 2003-12-04 Gala Design, Inc. Selection free growth of host cells containing multiple integrating vectors
KR100545945B1 (ko) * 2000-07-03 2006-01-25 갈라 디자인, 인크. 발현 벡터
AU2001271614B2 (en) * 2000-07-03 2007-05-31 Catalent Pharma Solutions, Llc Host cells containing multiple integrating vectors
CA2442066C (en) 2001-04-02 2005-11-01 Wyeth Pd-1, a receptor for b7-4, and uses therefor
WO2003029422A2 (en) * 2001-10-01 2003-04-10 Mount Sinai School Of Medicine Noonan syndrome gene
US20040038304A1 (en) * 2002-03-28 2004-02-26 Gala Design, Inc. Antibody libraries
US7384738B2 (en) * 2002-03-28 2008-06-10 Bremel Robert D Retrovirus-based genomic screening
US20050221429A1 (en) * 2004-01-16 2005-10-06 Cardinal Health Pts, Llc Host cells containing multiple integrating vectors comprising an amplifiable marker
US20090111786A1 (en) * 2004-12-03 2009-04-30 Glass Christopher K Compounds that Prevent Macrophage Apoptosis and Uses Thereof
US20130203059A1 (en) * 2010-07-02 2013-08-08 Topogen, Inc. Method for Diagnosis of Bladder Cancer and Related Kits
WO2014022759A1 (en) 2012-08-03 2014-02-06 Dana-Farber Cancer Institute, Inc. Agents that modulate immune cell activation and methods of use thereof
CN108350030B (zh) * 2015-09-10 2022-12-13 汉阳大学校产学协力团 皮肤可渗透肽及其使用方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0471825A4 (en) * 1990-03-02 1993-06-09 Applied Biotechnology, Inc. Ptpase diagnostics and uses thereof
ATE123064T1 (de) * 1990-03-14 1995-06-15 Washington Res Found Methoden und zusammensetzungen zur behandlung von bösartigen entartungen, die in zusammenhang mit einer proteinkinase stehen.
ATE182624T1 (de) * 1990-07-11 1999-08-15 Univ New York Phosphotyrosin phosphatase als neuer rezeptor-typ

Also Published As

Publication number Publication date
WO1994003611A2 (en) 1994-02-17
JPH08501934A (ja) 1996-03-05
US5831009A (en) 1998-11-03
WO1994003611A3 (en) 1994-03-31
US5955592A (en) 1999-09-21
PT654083E (pt) 2003-08-29
CN1091139A (zh) 1994-08-24
AU4707793A (en) 1994-03-03
DE69332883D1 (de) 2003-05-22
MX9304769A (es) 1994-05-31
DK0654083T3 (da) 2003-08-11
EP0654083B1 (en) 2003-04-16
EP0654083A1 (en) 1995-05-24
DE69332883T2 (de) 2004-01-22
ATE237688T1 (de) 2003-05-15
CA2141847A1 (en) 1994-02-17

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