DE69110034D1 - Methoden und zusammensetzungen zur behandlung von bösartigen entartungen, die in zusammenhang mit einer proteinkinase stehen. - Google Patents

Methoden und zusammensetzungen zur behandlung von bösartigen entartungen, die in zusammenhang mit einer proteinkinase stehen.

Info

Publication number
DE69110034D1
DE69110034D1 DE69110034T DE69110034T DE69110034D1 DE 69110034 D1 DE69110034 D1 DE 69110034D1 DE 69110034 T DE69110034 T DE 69110034T DE 69110034 T DE69110034 T DE 69110034T DE 69110034 D1 DE69110034 D1 DE 69110034D1
Authority
DE
Germany
Prior art keywords
compositions
methods
protein kinase
malignancies
gene transfer
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69110034T
Other languages
English (en)
Other versions
DE69110034T2 (de
Inventor
Edmond Fischer
Edwin Krebs
Nicholas Tonks
Deborah Cool
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Washington Research Foundation
Original Assignee
Washington Research Foundation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Washington Research Foundation filed Critical Washington Research Foundation
Application granted granted Critical
Publication of DE69110034D1 publication Critical patent/DE69110034D1/de
Publication of DE69110034T2 publication Critical patent/DE69110034T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Manufacture Of Motors, Generators (AREA)
  • Bending Of Plates, Rods, And Pipes (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
DE69110034T 1990-03-14 1991-03-14 Methoden und zusammensetzungen zur behandlung von bösartigen entartungen, die in zusammenhang mit einer proteinkinase stehen. Expired - Fee Related DE69110034T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US49403690A 1990-03-14 1990-03-14
PCT/US1991/001748 WO1991013989A1 (en) 1990-03-14 1991-03-14 Methods and compositions for the treatment of malignancies in which a protein kinase is associated

Publications (2)

Publication Number Publication Date
DE69110034D1 true DE69110034D1 (de) 1995-06-29
DE69110034T2 DE69110034T2 (de) 1995-10-05

Family

ID=23962758

Family Applications (2)

Application Number Title Priority Date Filing Date
DE69130117T Expired - Lifetime DE69130117D1 (de) 1990-03-14 1991-03-14 Methode und Zusammensetzungen zur Behandlung von bösartigen Entartungen, die in Zusammenhang mit einer Proteinkinase stehen
DE69110034T Expired - Fee Related DE69110034T2 (de) 1990-03-14 1991-03-14 Methoden und zusammensetzungen zur behandlung von bösartigen entartungen, die in zusammenhang mit einer proteinkinase stehen.

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DE69130117T Expired - Lifetime DE69130117D1 (de) 1990-03-14 1991-03-14 Methode und Zusammensetzungen zur Behandlung von bösartigen Entartungen, die in Zusammenhang mit einer Proteinkinase stehen

Country Status (9)

Country Link
EP (2) EP0627489B1 (de)
JP (1) JPH05505527A (de)
AT (2) ATE123064T1 (de)
CA (1) CA2078010A1 (de)
DE (2) DE69130117D1 (de)
DK (1) DK0520029T3 (de)
ES (1) ES2073165T3 (de)
GR (1) GR3017164T3 (de)
WO (1) WO1991013989A1 (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE911115A1 (en) * 1990-04-10 1991-10-23 Canji Inc Gene therapy for cell proliferative diseases
US5536636A (en) * 1991-06-26 1996-07-16 Beth Israel Hospital Methods for identifying a tyrosine phosphatase abnormality associated with neoplastic disease
GB9214754D0 (en) * 1992-07-10 1992-08-19 Univ Singapore Tumour treatment
MX9304769A (es) * 1992-08-05 1994-05-31 Max Planck Gesellschaft Subfamilia ptp-d de fosfatasas de la proteina tirosina.
AU6688696A (en) * 1995-08-10 1997-03-05 Incyte Pharmaceuticals, Inc. Non-receptor type human protein tyrosine phosphatase
US6238902B1 (en) 1996-03-22 2001-05-29 Genentech, Inc. Protein tyrosine phosphatases
IL125939A (en) * 1996-03-22 2008-06-05 Genentech Inc Protein tyrosine phosphatases of hematopoietic cells
US7176289B1 (en) 1998-09-11 2007-02-13 Vanderbilt University Modulation of endothelial cell surface receptor activity in the regulation of angiogenesis
US6248327B1 (en) 1998-09-11 2001-06-19 Vanderbilt University Modulation of endothelial cell surface receptor activity in the regulation of angiogenesis
US6485974B1 (en) * 2001-05-18 2002-11-26 Isis Pharmaceuticals, Inc. Antisense modulation of PTPN2 expression

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4710469A (en) * 1986-05-02 1987-12-01 Merck & Co., Inc. Novel phosphotyrosyl protein phosphatase

Also Published As

Publication number Publication date
DK0520029T3 (da) 1995-10-16
ATE123064T1 (de) 1995-06-15
EP0520029A1 (de) 1992-12-30
EP0627489B1 (de) 1998-09-02
ATE170561T1 (de) 1998-09-15
DE69130117D1 (de) 1998-10-08
DE69110034T2 (de) 1995-10-05
EP0520029B1 (de) 1995-05-24
EP0627489A1 (de) 1994-12-07
JPH05505527A (ja) 1993-08-19
ES2073165T3 (es) 1995-08-01
CA2078010A1 (en) 1992-09-15
WO1991013989A1 (en) 1991-09-19
GR3017164T3 (en) 1995-11-30

Similar Documents

Publication Publication Date Title
ES2170366T3 (es) Secuencia de adn aislada del gen brca1 y su utilizacion en terapia antitumoral.
DE69131255D1 (de) Immunreaktivität gegenüber exprimierten aktivierten Oncogenen zur Diagnose und Behandlung von bösartigen Geschwülsten
ATE202801T1 (de) Verfahren zum nachweis, identifizieren und quantifizieren von organismen und viren
ATE223727T1 (de) Erkennung und modulierung von iaps und naip zur diagnose und behandlung von proliferativen erkrankungen
ATE380195T1 (de) Zusammensetzungen und verfahren zur behandlung von tumoren
DE69708865D1 (de) Verfahren zur direkten sequenzierung während "template"-amplifikation
DE69110034D1 (de) Methoden und zusammensetzungen zur behandlung von bösartigen entartungen, die in zusammenhang mit einer proteinkinase stehen.
ATE154947T1 (de) Oligonukleotide zur modulation der effekte von cytomegalovirusinfektionen
ATE315663T1 (de) Universelle zielsequenzen zur identifizierung von tierarten
DE69824597D1 (de) Ikk-beta proteine, nukleinsäuren und verfahren
DE3854137D1 (de) Verfahren zur Isolierung von Nukleinsäuren.
DE69635848D1 (de) Verfahren zum Nachweis von Ki-ras Mutationen
ATE108205T1 (de) Rekombinantverfahren zur herstellung von serinproteaseinhibitoren, sowie dns-sequenzen dazu.
DE60136669D1 (de) Träger zum Nachweis von Genen und seine Verwendung zur Feststellung der Wirksamkeit einer Interferontherapie
ATE488529T1 (de) Zusammensetzungen und verfahren zur behandlung von tumoren
DE69628449D1 (de) Verfahren zur identifizierung unbekannter allele
ATE305051T1 (de) Genetische marker und methoden zum detektion von escherichia coli serotype-0157:h7
DE69021742D1 (de) Verfahren zum Nachweis von kleinzelligem Carzinom und die Verwendung von Sequenzen, die Acylpeptid-Hydrolase codieren, für diesen zweck.
ATE466938T1 (de) Prostata-spezifisches gen pcgem1 und methoden zu dessen verwendung zur erkennung, behandlung und prävention von prostatakrebs
ATE224453T1 (de) Verwendung eines spezifischen markers zur detektion von salmonellen mit pcr
SE7806087L (sv) Forfarande for rening av nukleotidsekvenser lempliga som syntetiseringsmall i bakterier, mikroorganism innefattande dylik nukleotidsekvens samt rekombinant dna-overforingsvektor innefattande dylik nukleotid
ATE185377T1 (de) Genomische genkartierungsmethode durch direkten nachweis von haplotypen mittels intronsequenzanalyse
DE59008012D1 (de) Mittel zur Behandlung von Leder und Pelzen.
WO2002044419A3 (en) Expression analysis of kiaa nucleic acids and polypeptides useful in the diagnosis and treatment of prostate cancer
ATE125713T1 (de) Verfahren zur inaktivierung der biologischen aktivität von dna.

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee