DE3485319D1 - Rekombinante dns, diese rekombinante dns enthaltende bakterien, und verfahren zur herstellung von l-threonin oder l-isoleucin unter verwendung dieser bakterien. - Google Patents

Rekombinante dns, diese rekombinante dns enthaltende bakterien, und verfahren zur herstellung von l-threonin oder l-isoleucin unter verwendung dieser bakterien.

Info

Publication number
DE3485319D1
DE3485319D1 DE8484111003T DE3485319T DE3485319D1 DE 3485319 D1 DE3485319 D1 DE 3485319D1 DE 8484111003 T DE8484111003 T DE 8484111003T DE 3485319 T DE3485319 T DE 3485319T DE 3485319 D1 DE3485319 D1 DE 3485319D1
Authority
DE
Germany
Prior art keywords
recombinant dna
bacteria
isoleucin
threonin
producing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE8484111003T
Other languages
English (en)
Inventor
Shigeru Nakamori
Hiroshi Takagi
Masaaki Ishida
Takaaki Sato
Kiyoshi Miwa
Konosuke Sano
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ajinomoto Co Inc
Original Assignee
Ajinomoto Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ajinomoto Co Inc filed Critical Ajinomoto Co Inc
Application granted granted Critical
Publication of DE3485319D1 publication Critical patent/DE3485319D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00Preparation of nitrogen-containing organic compounds
    • C12P13/04Alpha- or beta- amino acids
    • C12P13/08Lysine; Diaminopimelic acid; Threonine; Valine
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/74Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
    • C12N15/77Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for Corynebacterium; for Brevibacterium
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10Transferases (2.)
    • C12N9/12Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00Preparation of nitrogen-containing organic compounds
    • C12P13/04Alpha- or beta- amino acids
    • C12P13/06Alanine; Leucine; Isoleucine; Serine; Homoserine
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00Chemistry: molecular biology and microbiology
    • Y10S435/8215Microorganisms
    • Y10S435/822Microorganisms using bacteria or actinomycetales
    • Y10S435/84Brevibacterium
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00Chemistry: molecular biology and microbiology
    • Y10S435/8215Microorganisms
    • Y10S435/822Microorganisms using bacteria or actinomycetales
    • Y10S435/843Corynebacterium

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
DE8484111003T 1983-09-14 1984-09-14 Rekombinante dns, diese rekombinante dns enthaltende bakterien, und verfahren zur herstellung von l-threonin oder l-isoleucin unter verwendung dieser bakterien. Expired - Lifetime DE3485319D1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP58170005A JPS6062982A (ja) 1983-09-14 1983-09-14 組換えdνa,該組換えdνaを有する細菌及び該細菌を用いるl−スレオニン又はl−イソロイシンの製造法

Publications (1)

Publication Number Publication Date
DE3485319D1 true DE3485319D1 (de) 1992-01-16

Family

ID=15896819

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8484111003T Expired - Lifetime DE3485319D1 (de) 1983-09-14 1984-09-14 Rekombinante dns, diese rekombinante dns enthaltende bakterien, und verfahren zur herstellung von l-threonin oder l-isoleucin unter verwendung dieser bakterien.

Country Status (4)

Country Link
US (1) US4946781A (de)
EP (1) EP0137348B1 (de)
JP (1) JPS6062982A (de)
DE (1) DE3485319D1 (de)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0746994B2 (ja) * 1984-10-04 1995-05-24 味の素株式会社 発酵法によるl−アミノ酸の製造法
DE3684511D1 (de) * 1985-06-05 1992-04-30 Kyowa Hakko Kogyo Kk Verfahren zur herstellung von l-threonin und l-isoleucin.
JPS6291193A (ja) * 1985-06-05 1987-04-25 Kyowa Hakko Kogyo Co Ltd L−スレオニンおよびl−イソロイシンの製造法
JPS62232392A (ja) * 1986-04-02 1987-10-12 Kyowa Hakko Kogyo Co Ltd L−スレオニンおよびl−イソロイシンの製造法
JPH07112431B2 (ja) * 1985-09-06 1995-12-06 味の素株式会社 遺伝子発現調節法
JPS62186795A (ja) * 1986-02-12 1987-08-15 Kyowa Hakko Kogyo Co Ltd アミノ酸の製造法
EP0312089B1 (de) * 1987-10-15 1994-03-02 Mitsubishi Petrochemical Co., Ltd. Verfahren zur Herstellung von L-Threonin
DE3942947A1 (de) * 1989-12-23 1991-06-27 Forschungszentrum Juelich Gmbh Verfahren zur herstellung von l-isoleucin und dafuer geeignete mikroorganismen und rekombinante dna
JPH06327480A (ja) * 1993-05-20 1994-11-29 Mitsubishi Petrochem Co Ltd プラスミドの自律複製を司る機能に関与する遺伝子を含むdna断片
US5939307A (en) * 1996-07-30 1999-08-17 The Archer-Daniels-Midland Company Strains of Escherichia coli, methods of preparing the same and use thereof in fermentation processes for l-threonine production
US7220571B2 (en) 2000-09-28 2007-05-22 Archer-Daniels-Midland Company Escherichia coli strains which over-produce L-threonine and processes for the production of L-threonine by fermentation
US7723097B2 (en) * 2005-03-11 2010-05-25 Archer-Daniels-Midland Company Escherichia coli strains that over-produce L-threonine and processes for their production
EP1899472B1 (de) * 2005-06-20 2017-09-27 Archer-Daniels-Midland Company Geänderter glyoxylat-shunt zur verbesserten produktion von aspartat abgeleiteten aminosäuren und chemikalien
CN111315888A (zh) * 2018-10-30 2020-06-19 绿色地球研究所株式会社 有机化合物的制造方法及棒状细菌

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS57186496A (en) * 1981-05-11 1982-11-16 Ajinomoto Co Inc Preparation of l-threonine by fermentation
JPS58893A (ja) * 1981-06-25 1983-01-06 Ajinomoto Co Inc 発酵法によるl−イソロイシンの製造法
IL67510A (en) * 1981-12-17 1988-08-31 Kyowa Hakko Kogyo Kk Recombinant vector plasmids autonomously replicable in microorganisms belonging to the genus corynebacterium or brevibacterium and process for the production thereof
JPS58126789A (ja) * 1981-12-29 1983-07-28 Kyowa Hakko Kogyo Co Ltd レースレオニンの製造法
US4601983A (en) * 1983-06-15 1986-07-22 Ajinomoto Co., Inc. Coryneform bacteria carrying recombinant plasmids and their use in the fermentative production of L-threonine and L-isoleucine

Also Published As

Publication number Publication date
JPS6062982A (ja) 1985-04-11
US4946781A (en) 1990-08-07
EP0137348B1 (de) 1991-12-04
EP0137348A2 (de) 1985-04-17
EP0137348A3 (en) 1987-05-27

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