DE69129272D1 - Dextrinsulfate als anti hiv-1 wirkstoffe und diese enthaltende zubereitungen - Google Patents

Dextrinsulfate als anti hiv-1 wirkstoffe und diese enthaltende zubereitungen

Info

Publication number
DE69129272D1
DE69129272D1 DE69129272T DE69129272T DE69129272D1 DE 69129272 D1 DE69129272 D1 DE 69129272D1 DE 69129272 T DE69129272 T DE 69129272T DE 69129272 T DE69129272 T DE 69129272T DE 69129272 D1 DE69129272 D1 DE 69129272D1
Authority
DE
Germany
Prior art keywords
pct
agent
dextrine
sulfate
active substances
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69129272T
Other languages
English (en)
Other versions
DE69129272T2 (de
Inventor
Donald Selwyn Davies
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Innovata Ltd
Original Assignee
ML Laboratories PLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ML Laboratories PLC filed Critical ML Laboratories PLC
Publication of DE69129272D1 publication Critical patent/DE69129272D1/de
Application granted granted Critical
Publication of DE69129272T2 publication Critical patent/DE69129272T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B31/00—Preparation of derivatives of starch
    • C08B31/02—Esters
    • C08B31/06—Esters of inorganic acids
    • C08B31/063—Starch sulfates

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Virology (AREA)
  • Polymers & Plastics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Communicable Diseases (AREA)
  • Inorganic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Materials Engineering (AREA)
  • Epidemiology (AREA)
  • AIDS & HIV (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DE69129272T 1990-09-25 1991-09-23 Dextrinsulfate als anti hiv-1 wirkstoffe und diese enthaltende zubereitungen Expired - Fee Related DE69129272T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB909020861A GB9020861D0 (en) 1990-09-25 1990-09-25 Pharmaceutical compositions
PCT/GB1991/001628 WO1992004904A1 (en) 1990-09-25 1991-09-23 Dextrin sulfates as anti hiv-1 agents and composition thereof

Publications (2)

Publication Number Publication Date
DE69129272D1 true DE69129272D1 (de) 1998-05-20
DE69129272T2 DE69129272T2 (de) 1998-11-12

Family

ID=10682722

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69129272T Expired - Fee Related DE69129272T2 (de) 1990-09-25 1991-09-23 Dextrinsulfate als anti hiv-1 wirkstoffe und diese enthaltende zubereitungen

Country Status (15)

Country Link
US (2) US5439892A (de)
EP (1) EP0550532B1 (de)
JP (1) JP3281373B2 (de)
AT (1) ATE165005T1 (de)
AU (1) AU649731B2 (de)
CA (1) CA2092094C (de)
DE (1) DE69129272T2 (de)
DK (1) DK0550532T3 (de)
ES (1) ES2113888T3 (de)
GB (1) GB9020861D0 (de)
IE (1) IE913340A1 (de)
NZ (1) NZ239908A (de)
PT (1) PT99057B (de)
WO (1) WO1992004904A1 (de)
ZA (1) ZA917597B (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9625193D0 (en) * 1996-12-04 1997-01-22 Ml Lab Plc Treatment of highly vascular tumours
JP2002508758A (ja) 1997-06-12 2002-03-19 エムエル・ラボラトリーズ・パブリック・リミテッド・カンパニー 生物的に活性な材料
US6077503A (en) * 1997-07-30 2000-06-20 Amway Corporation Skin whitener composition containing mercaptodextran
US20050209189A1 (en) * 2001-03-06 2005-09-22 Roger Hershline Antiviral composition
US6821958B1 (en) 2001-03-06 2004-11-23 Roger K. Hershline Antiviral composition
JP2005519049A (ja) * 2001-12-24 2005-06-30 エムエル・ラボラトリーズ・パブリック・リミテッド・カンパニー 硫酸デキストリンを含む性感染症（ｓｔｄ）治療用組成物
US20030181416A1 (en) * 2002-01-10 2003-09-25 Comper Wayne D. Antimicrobial charged polymers that exhibit resistance to lysosomal degradation during kidney filtration and renal passage, compositions and method of use thereof
US20040009953A1 (en) * 2002-01-10 2004-01-15 Comper Wayne D. Antimicrobial charged polymers that exhibit resistance to lysosomal degradation during kidney filtration and renal passage, compositions and method of use thereof
WO2004064850A1 (en) * 2003-01-23 2004-08-05 Ml Laboratories Plc Antiviral composition comprising a sulphated glucose polymer and a bacteriostatic agent
US20050009782A1 (en) * 2003-07-09 2005-01-13 Comper Wayne D. Antiviral charged polymers that exhibit resistance to lysosomal degradation during kidney filtration and renal passage, compositions and methods of use thereof
US7285582B2 (en) * 2004-12-30 2007-10-23 Conocophillips Company Modified latex drag reducer and processes therefor and therewith
US20070225191A1 (en) * 2006-03-27 2007-09-27 The Procter & Gamble Company Methods for modifying bioplymers in ionic liquids

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2967178A (en) * 1957-12-06 1961-01-03 Corn Products Co Method of producing gelling starch of high clarity
US3017407A (en) * 1958-08-18 1962-01-16 Riker Laboratories Inc Process for producing polysulfuric acid esters of polysaccharides
US3070595A (en) * 1960-10-28 1962-12-25 Riker Laboratories Inc Process for producing polysulfuric acid esters of polysaccharides
DE3601136A1 (de) * 1986-01-16 1987-07-23 Max Planck Gesellschaft Hemmstoffe der reversen transkriptase fuer prophylaxe und therapie von retrovirus-infektionen in saeugetieren
EP0240098A3 (de) * 1986-04-04 1989-05-10 Kabushiki Kaisha Ueno Seiyaku Oyo Kenkyujo Oligo und Polysaccharide zur Behandlung von Krankheiten verursacht durch Retroviren
SE453394B (sv) * 1986-07-07 1988-02-01 Pharmacia Ab Forfarande for framstellning av sulfaterade polysackarider genom anvendning av ett reducerande medel for sulfateringsreaktionen
WO1989003684A1 (en) * 1987-10-30 1989-05-05 Chugai Seiyaku Kabushiki Kaisha Anti-hiv agent
GB9001687D0 (en) * 1990-01-25 1990-03-28 Ml Lab Plc Treatment of poisoning and composition for use therein
US5221669A (en) * 1991-04-19 1993-06-22 The United States Of America As Represented By The Department Of Health And Human Services Antiviral compositions containing α-cyclodextrin sulfates alone and in combination with other known antiviral agents and glucocorticoids and methods of treating viral infections

Also Published As

Publication number Publication date
EP0550532B1 (de) 1998-04-15
AU8614591A (en) 1992-04-15
GB9020861D0 (en) 1990-11-07
PT99057B (pt) 1999-02-26
IE913340A1 (en) 1992-02-25
CA2092094A1 (en) 1992-03-26
AU649731B2 (en) 1994-06-02
US6015799A (en) 2000-01-18
DK0550532T3 (da) 1999-03-08
DE69129272T2 (de) 1998-11-12
JP3281373B2 (ja) 2002-05-13
US5439892A (en) 1995-08-08
ZA917597B (en) 1992-05-27
PT99057A (pt) 1992-08-31
JPH06503305A (ja) 1994-04-14
WO1992004904A1 (en) 1992-04-02
CA2092094C (en) 2004-08-10
ATE165005T1 (de) 1998-05-15
ES2113888T3 (es) 1998-05-16
NZ239908A (en) 1993-03-26
EP0550532A1 (de) 1993-07-14

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee