DE69125619T2 - Arzneimittel mit kontrollierter wirkstoffabgabe - Google Patents

Arzneimittel mit kontrollierter wirkstoffabgabe

Info

Publication number
DE69125619T2
DE69125619T2 DE69125619T DE69125619T DE69125619T2 DE 69125619 T2 DE69125619 T2 DE 69125619T2 DE 69125619 T DE69125619 T DE 69125619T DE 69125619 T DE69125619 T DE 69125619T DE 69125619 T2 DE69125619 T2 DE 69125619T2
Authority
DE
Germany
Prior art keywords
active substances
controlled delivery
medicinal products
core
vinylpyrrolidine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69125619T
Other languages
English (en)
Other versions
DE69125619D1 (de
Inventor
John Michael Newton
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
BTG International Ltd
Original Assignee
British Technology Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by British Technology Group Ltd filed Critical British Technology Group Ltd
Application granted granted Critical
Publication of DE69125619D1 publication Critical patent/DE69125619D1/de
Publication of DE69125619T2 publication Critical patent/DE69125619T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/2853—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers, poly(lactide-co-glycolide)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2009—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
    • A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Inorganic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Lubricants (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
  • Glass Compositions (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Air Bags (AREA)
  • Valve Device For Special Equipments (AREA)
  • Control Of Throttle Valves Provided In The Intake System Or In The Exhaust System (AREA)
DE69125619T 1990-11-22 1991-11-21 Arzneimittel mit kontrollierter wirkstoffabgabe Expired - Fee Related DE69125619T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB909025372A GB9025372D0 (en) 1990-11-22 1990-11-22 Pharmaceutical dosage forms
PCT/GB1991/002057 WO1992009270A1 (en) 1990-11-22 1991-11-21 Controlled release compositions

Publications (2)

Publication Number Publication Date
DE69125619D1 DE69125619D1 (de) 1997-05-15
DE69125619T2 true DE69125619T2 (de) 1997-09-11

Family

ID=10685781

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69125619T Expired - Fee Related DE69125619T2 (de) 1990-11-22 1991-11-21 Arzneimittel mit kontrollierter wirkstoffabgabe

Country Status (14)

Country Link
EP (1) EP0559813B1 (de)
JP (1) JPH06502636A (de)
KR (1) KR930701984A (de)
AT (1) ATE151283T1 (de)
AU (1) AU653372B2 (de)
CA (1) CA2096733A1 (de)
DE (1) DE69125619T2 (de)
ES (1) ES2101082T3 (de)
FI (1) FI932320A (de)
GB (2) GB9025372D0 (de)
HU (1) HUT65756A (de)
NO (1) NO931859L (de)
WO (1) WO1992009270A1 (de)
ZA (1) ZA919185B (de)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102004042139A1 (de) * 2004-08-31 2006-03-02 Henning Prof. Dr. Blume Perorale Darreichungsformen zur Erzielung eines Retardierungseffektes nach der Arzneimitteleinnahme mit einer Mahlzeit

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU653203B2 (en) * 1991-01-30 1994-09-22 Wellcome Foundation Limited, The Water-dispersible tablets
US5629016A (en) * 1991-01-30 1997-05-13 Glaxo Wellcome Inc. Water-dispersible tablets
GB9215908D0 (en) * 1992-07-27 1992-09-09 Wellcome Found Water dispersible tablets
TW246635B (de) * 1992-10-08 1995-05-01 Shell Internat Res Schappej B V
DK66493D0 (da) * 1993-06-08 1993-06-08 Ferring A S Praeparater, isaer til brug ved behandling af inflammatoriske tarmsygdomme eller til at opnaa forbedret saarheling
US5698226A (en) * 1993-07-13 1997-12-16 Glaxo Wellcome Inc. Water-dispersible tablets
US6028190A (en) 1994-02-01 2000-02-22 The Regents Of The University Of California Probes labeled with energy transfer coupled dyes
US6166024A (en) 1995-03-30 2000-12-26 Mayo Foundation For Medical Education And Research Use of topical azathioprine and thioguanine to treat colorectal adenomas
TW474824B (en) 1996-09-13 2002-02-01 Basf Ag The production of solid pharmaceutical forms
DE19649100A1 (de) * 1996-11-27 1998-06-04 Lohmann Therapie Syst Lts Verfahren zur verlustarmen Herstellung wirkstoffhaltiger scheibenförmiger Formkörper und diese enthaltende transdermale therapeutische Systeme
DK1067910T3 (da) 1998-04-03 2004-10-04 Egalet As Komposition med styret afgivelse
DE19840256A1 (de) * 1998-09-03 2000-03-09 Basf Ag Verfahren zur Herstellung von beschichteten festen Dosierungsformen
CA2360655C (en) 1999-01-29 2007-03-20 Losan Pharma Gmbh Pharmaceutical compositions
WO2002005788A1 (en) * 2000-07-14 2002-01-24 Universiteit Gent Composite solid shaped articles for the controlled delivery of biologically active ingredients
EP2957281A1 (de) 2001-09-21 2015-12-23 Egalet Ltd. Polymer-freigabe-system
US20040253310A1 (en) 2001-09-21 2004-12-16 Gina Fischer Morphine polymer release system
US20030203027A1 (en) * 2002-04-26 2003-10-30 Ethicon, Inc. Coating technique for deposition of drug substance on a substrate
EP1503731A1 (de) * 2002-05-07 2005-02-09 Control Delivery Systems, Inc. Herstellungsverfahren einer arzneimittelverabreichungsvorrichtung
GB0214013D0 (en) 2002-06-18 2002-07-31 Euro Celtique Sa Pharmaceutical product
WO2004041252A1 (en) 2002-11-08 2004-05-21 Egalet A/S Controlled release carvedilol compositions
WO2004084868A1 (en) 2003-03-26 2004-10-07 Egalet A/S Morphine controlled release system
ATE399538T1 (de) 2003-03-26 2008-07-15 Egalet As Matrixzubereitungen für die kontrollierte darreichung von arzneistoffen
CA2687192C (en) 2007-06-04 2015-11-24 Egalet A/S Controlled release pharmaceutical compositions for prolonged effect
CA2751667C (en) 2009-02-06 2016-12-13 Egalet Ltd. Immediate release composition resistant to abuse by intake of alcohol
NZ597283A (en) 2009-06-24 2013-07-26 Egalet Ltd Controlled release formulations
BR112012022363A2 (pt) * 2010-03-04 2016-07-05 Wockhardt Ltd forma de dosagem com liberação modificada
EA201590165A1 (ru) 2012-07-06 2015-08-31 Эгалет Лтд. Сдерживающие злоупотребление фармацевтические композиции для контролируемого высвобождения
JP7407595B2 (ja) * 2016-10-05 2024-01-04 タイタン ファーマシューティカルズ インコーポレイテッド バースト放出を低減する薬剤送達用の埋込可能な装置

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK62184D0 (da) * 1984-02-10 1984-02-10 Benzon As Alfred Diffusionsovertrukket polydepotpraeparat
GB2170104A (en) * 1985-01-30 1986-07-30 Warner Lambert Co Coated pharmaceutical dosage forms
IE861284L (en) * 1986-05-14 1987-11-14 Birex Res And Dev Ltd And Carm Controlled release ketoprofen.
US4810501A (en) * 1986-06-17 1989-03-07 Warner-Lambert Company Sustained release pharmaceutical preparations
GB8618811D0 (en) * 1986-08-01 1986-09-10 Approved Prescription Services Sustained release ibuprofen formulation
US5158881A (en) * 1987-11-17 1992-10-27 Brown University Research Foundation Method and system for encapsulating cells in a tubular extrudate in separate cell compartments

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102004042139A1 (de) * 2004-08-31 2006-03-02 Henning Prof. Dr. Blume Perorale Darreichungsformen zur Erzielung eines Retardierungseffektes nach der Arzneimitteleinnahme mit einer Mahlzeit
DE102004042139B4 (de) * 2004-08-31 2009-06-10 Aristocon Verwaltungs- Gmbh Perorale Darreichungsformen zur Erzielung eines Retardierungseffektes nach der Arzneimitteleinnahme mit einer Mahlzeit

Also Published As

Publication number Publication date
KR930701984A (ko) 1993-09-08
HU9301499D0 (en) 1993-09-28
EP0559813A1 (de) 1993-09-15
ZA919185B (en) 1992-09-30
FI932320A0 (fi) 1993-05-21
GB9124776D0 (en) 1992-01-15
JPH06502636A (ja) 1994-03-24
HUT65756A (en) 1994-07-28
ES2101082T3 (es) 1997-07-01
GB2249957B (en) 1994-11-23
NO931859D0 (no) 1993-05-21
DE69125619D1 (de) 1997-05-15
AU8909691A (en) 1992-06-25
AU653372B2 (en) 1994-09-29
EP0559813B1 (de) 1997-04-09
GB2249957A (en) 1992-05-27
NO931859L (no) 1993-07-21
WO1992009270A1 (en) 1992-06-11
FI932320A (fi) 1993-07-09
ATE151283T1 (de) 1997-04-15
CA2096733A1 (en) 1992-05-23
GB9025372D0 (en) 1991-01-09

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee