DE69124297T2 - Grössenmarker für elektrophoretische Analyse von DNS - Google Patents

Grössenmarker für elektrophoretische Analyse von DNS

Info

Publication number
DE69124297T2
DE69124297T2 DE69124297T DE69124297T DE69124297T2 DE 69124297 T2 DE69124297 T2 DE 69124297T2 DE 69124297 T DE69124297 T DE 69124297T DE 69124297 T DE69124297 T DE 69124297T DE 69124297 T2 DE69124297 T2 DE 69124297T2
Authority
DE
Germany
Prior art keywords
probe
dna
fragments
complementary
ladder
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69124297T
Other languages
English (en)
Other versions
DE69124297D1 (de
Inventor
David P Carlson
Paul C Watkins
Leonard Klevan
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Global Life Sciences Solutions USA LLC
Original Assignee
Life Technologies Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Life Technologies Inc filed Critical Life Technologies Inc
Publication of DE69124297D1 publication Critical patent/DE69124297D1/de
Application granted granted Critical
Publication of DE69124297T2 publication Critical patent/DE69124297T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6827—Hybridisation assays for detection of mutation or polymorphism
    • C12Q1/683—Hybridisation assays for detection of mutation or polymorphism involving restriction enzymes, e.g. restriction fragment length polymorphism [RFLP]
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/967—Standards, controls, materials, e.g. validation studies, buffer systems
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/10—Composition for standardization, calibration, simulation, stabilization, preparation or preservation; processes of use in preparation for chemical testing

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Virology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
DE69124297T 1990-07-13 1991-07-04 Grössenmarker für elektrophoretische Analyse von DNS Expired - Fee Related DE69124297T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/552,406 US5316908A (en) 1990-07-13 1990-07-13 Size markers for electrophoretic analysis of DNA

Publications (2)

Publication Number Publication Date
DE69124297D1 DE69124297D1 (de) 1997-03-06
DE69124297T2 true DE69124297T2 (de) 1997-05-28

Family

ID=24205190

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69124297T Expired - Fee Related DE69124297T2 (de) 1990-07-13 1991-07-04 Grössenmarker für elektrophoretische Analyse von DNS

Country Status (5)

Country Link
US (1) US5316908A (de)
EP (1) EP0466404B1 (de)
AT (1) ATE148174T1 (de)
CA (1) CA2045794A1 (de)
DE (1) DE69124297T2 (de)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5714326A (en) * 1991-01-24 1998-02-03 Dawson; Elliott P. Method for the multiplexed preparation of nucleic acid molecular weight markers and resultant products
WO1993014224A1 (en) * 1992-01-14 1993-07-22 Applied Biosystems, Inc. Size-calibration dna fragment mixture and method
US5302510A (en) * 1992-07-27 1994-04-12 Life Technologies, Inc. DNA sizing control standards for electrophoretic analyses
DK0725821T3 (da) * 1993-10-28 1999-02-15 Life Technologies Inc Nucleinsyremarkørstige til estimering af masse
US6680378B1 (en) * 1993-10-28 2004-01-20 Invitrogen Corporation Nucleic acid marker ladder for estimating mass
ATE220087T1 (de) 1996-12-19 2002-07-15 Johnson S C Comm Markets Inc Dispersionen gemischter polycarboxypolyamid-harze und alkali-dispergierbarer harze; herstellung und ihre verwendung
ES2308800T3 (es) 1997-01-08 2008-12-01 Invitrogen Corporation Metodos para la produccion de proteinas.
WO1998044156A1 (en) 1997-03-27 1998-10-08 Life Technologies, Inc. Nucleic acid ladders
WO1999003872A1 (en) * 1997-07-15 1999-01-28 Life Technologies, Inc. Nucleic acid ladders
US6153389A (en) * 1999-02-22 2000-11-28 Haarer; Brian K. DNA additives as a mechanism for unambiguously marking biological samples
JP2002538837A (ja) * 1999-03-12 2002-11-19 アマシャム バイオサイエンス ユーケイ リミテッド 遺伝分析
JP4588835B2 (ja) * 1999-04-14 2010-12-01 株式会社ヘレナ研究所 リポ蛋白分離分析法、リポ蛋白分離分析装置、およびリポ蛋白分離分析システム
US6537785B1 (en) 1999-09-14 2003-03-25 Genzyme Glycobiology Research Institute, Inc. Methods of treating lysosomal storage diseases
US6998273B1 (en) * 2000-02-09 2006-02-14 A-Fem Medical Corporation Collection device for lateral flow chromatography
WO2002013848A1 (en) * 2000-08-11 2002-02-21 Invitrogen Corporation Highly homogeneous molecular markers for electrophoresis
US20030157720A1 (en) * 2002-02-06 2003-08-21 Expression Technologies Inc. Protein standard for estimating size and mass
US7727752B2 (en) * 2003-07-29 2010-06-01 Life Technologies Corporation Kinase and phosphatase assays
US7619059B2 (en) * 2003-07-29 2009-11-17 Life Technologies Corporation Bimolecular optical probes
ATE458200T1 (de) * 2003-09-12 2010-03-15 Life Technologies Corp Anwendungen des resonanzenergietransfers zwischen terbium und gfp
DE102007001370A1 (de) 2007-01-09 2008-07-10 Curevac Gmbh RNA-kodierte Antikörper
CA2959427A1 (en) 2014-09-19 2016-03-24 Li-Cor, Inc. Multifunctional protein molecular weight ladders
LT3423110T (lt) 2016-03-03 2021-12-27 University Of Massachusetts Linijinis dnr dupleksas su uždarais galais, skirtas nevirusiniam geno pernešimui
US11167247B2 (en) 2017-02-15 2021-11-09 Nanolc-12, Llc Length-based separation of carbon nanotubes
US11353424B2 (en) * 2018-04-12 2022-06-07 Nano LC-12, LLC Length-based carbon nanotube ladders
CN110923305B (zh) * 2019-11-25 2023-12-29 广州市达瑞生物技术股份有限公司 一种适用于脆性X综合征southern blot印迹杂交检测的DNA分子量标准
WO2024059197A1 (en) * 2022-09-14 2024-03-21 Revvity Health Sciences, Inc. Methods and compositions for single-stranded nucleic acid ladders by guided cleavage

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4458066A (en) * 1980-02-29 1984-07-03 University Patents, Inc. Process for preparing polynucleotides
US4500707A (en) * 1980-02-29 1985-02-19 University Patents, Inc. Nucleosides useful in the preparation of polynucleotides
US4668777A (en) * 1981-03-27 1987-05-26 University Patents, Inc. Phosphoramidite nucleoside compounds
US4415732A (en) * 1981-03-27 1983-11-15 University Patents, Inc. Phosphoramidite compounds and processes
US4762779A (en) * 1985-06-13 1988-08-09 Amgen Inc. Compositions and methods for functionalizing nucleic acids
JPH0697999B2 (ja) * 1986-06-25 1994-12-07 株式会社ヤクルト本社 Ｄｎａの分子量測定用標準マ−カ−
US4771384A (en) * 1986-07-24 1988-09-13 Dnastar, Inc. System and method for fragmentation mapping
US4965349A (en) * 1987-12-24 1990-10-23 Applied Biosystems, Inc. Method of synthesizing oligonucleotides labeled with ammonia-labile groups on solid phase supports
WO1989009780A1 (en) * 1988-04-15 1989-10-19 Chemical Industry Institute Of Toxicology Site-specific tritium-labeled oligodeoxynucleotides
DE3829535A1 (de) * 1988-08-31 1990-03-15 Biotest Ag Nukleinsaeure-fragmente aus eukaryontischen genomen, verfahren zu ihrer herstellung und ihre verwendung zum nachweis von restriktions-fragment-laengen-polymorphismen (rflps)

Also Published As

Publication number Publication date
DE69124297D1 (de) 1997-03-06
ATE148174T1 (de) 1997-02-15
EP0466404A1 (de) 1992-01-15
CA2045794A1 (en) 1992-01-14
US5316908A (en) 1994-05-31
EP0466404B1 (de) 1997-01-22

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: WHATMAN INC., NEWTON, MASS., US

8339 Ceased/non-payment of the annual fee