DE69120699D1 - N-Monosubstituierte Cyclopentenylamine, ein Verfahren zu ihrer Herstellung, und ihre Verwendung als Medikament - Google Patents

N-Monosubstituierte Cyclopentenylamine, ein Verfahren zu ihrer Herstellung, und ihre Verwendung als Medikament

Info

Publication number
DE69120699D1
DE69120699D1 DE69120699T DE69120699T DE69120699D1 DE 69120699 D1 DE69120699 D1 DE 69120699D1 DE 69120699 T DE69120699 T DE 69120699T DE 69120699 T DE69120699 T DE 69120699T DE 69120699 D1 DE69120699 D1 DE 69120699D1
Authority
DE
Germany
Prior art keywords
cyclopentenylamines
monosubstituted
medicament
preparation
medicaments
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69120699T
Other languages
English (en)
Other versions
DE69120699T2 (de
Inventor
Youichi Shiokawa
Kazuo Okumura
Kazuhiko Take
Kazunori Tsubaki
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Fujisawa Pharmaceutical Co Ltd
Original Assignee
Fujisawa Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB909005247A external-priority patent/GB9005247D0/en
Priority claimed from GB909021806A external-priority patent/GB9021806D0/en
Application filed by Fujisawa Pharmaceutical Co Ltd filed Critical Fujisawa Pharmaceutical Co Ltd
Application granted granted Critical
Publication of DE69120699D1 publication Critical patent/DE69120699D1/de
Publication of DE69120699T2 publication Critical patent/DE69120699T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C309/00—Sulfonic acids; Halides, esters, or anhydrides thereof
    • C07C309/01—Sulfonic acids
    • C07C309/25—Sulfonic acids having sulfo groups bound to carbon atoms of rings other than six-membered aromatic rings of a carbon skeleton
    • C07C309/26—Sulfonic acids having sulfo groups bound to carbon atoms of rings other than six-membered aromatic rings of a carbon skeleton containing nitrogen atoms, not being part of nitro or nitroso groups, bound to the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/02—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements
    • C07D295/027—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements containing only one hetero ring
    • C07D295/033—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements containing only one hetero ring with the ring nitrogen atoms directly attached to carbocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C211/00—Compounds containing amino groups bound to a carbon skeleton
    • C07C211/33—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of rings other than six-membered aromatic rings
    • C07C211/39—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of rings other than six-membered aromatic rings of an unsaturated carbon skeleton
    • C07C211/40—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of rings other than six-membered aromatic rings of an unsaturated carbon skeleton containing only non-condensed rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
    • C07C215/02—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C215/04—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being saturated
    • C07C215/06—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being saturated and acyclic
    • C07C215/08—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being saturated and acyclic with only one hydroxy group and one amino group bound to the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
    • C07C215/42—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having amino groups or hydroxy groups bound to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/02—Systems containing only non-condensed rings with a three-membered ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/04—Systems containing only non-condensed rings with a four-membered ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/06—Systems containing only non-condensed rings with a five-membered ring
    • C07C2601/08—Systems containing only non-condensed rings with a five-membered ring the ring being saturated
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/06—Systems containing only non-condensed rings with a five-membered ring
    • C07C2601/10—Systems containing only non-condensed rings with a five-membered ring the ring being unsaturated
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14—The ring being saturated
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/16—Systems containing only non-condensed rings with a six-membered ring the ring being unsaturated

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Neurology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Reproductive Health (AREA)
  • Pain & Pain Management (AREA)
  • Endocrinology (AREA)
  • Vascular Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pulmonology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Diaphragms For Electromechanical Transducers (AREA)
  • External Artificial Organs (AREA)
  • Hydrogenated Pyridines (AREA)
DE69120699T 1990-03-08 1991-03-06 N-Monosubstituierte Cyclopentenylamine, ein Verfahren zu ihrer Herstellung, und ihre Verwendung als Medikament Expired - Fee Related DE69120699T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB909005247A GB9005247D0 (en) 1990-03-08 1990-03-08 A novel substituted-amine compound and a process for the preparation thereof
GB909021806A GB9021806D0 (en) 1990-10-08 1990-10-08 A novel substituted-amine compound and a process for the preparation thereof

Publications (2)

Publication Number Publication Date
DE69120699D1 true DE69120699D1 (de) 1996-08-14
DE69120699T2 DE69120699T2 (de) 1997-01-09

Family

ID=26296763

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69120699T Expired - Fee Related DE69120699T2 (de) 1990-03-08 1991-03-06 N-Monosubstituierte Cyclopentenylamine, ein Verfahren zu ihrer Herstellung, und ihre Verwendung als Medikament

Country Status (14)

Country Link
US (1) US5256824A (de)
EP (1) EP0445749B1 (de)
JP (1) JPH0819058B2 (de)
KR (1) KR910016691A (de)
CN (1) CN1054586A (de)
AT (1) ATE140213T1 (de)
AU (1) AU645062B2 (de)
CA (1) CA2037721A1 (de)
DE (1) DE69120699T2 (de)
FI (1) FI911138A (de)
HU (2) HUT60710A (de)
IE (1) IE910752A1 (de)
NO (1) NO175679C (de)
PT (1) PT96967A (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4028046A1 (de) * 1990-09-05 1992-03-12 Bayer Ag Arzneimittel enthaltend substituierte 2-cyclohexen-1-yl-amin-derivate und ihre verwendung zur bekaempfung von krankheiten
PT789575E (pt) * 1994-11-02 2008-12-15 Nps Pharma Inc Canais de sódio específicos do sistema nervoso periférico, adn que os codificam, rastreio de medicamentos e métodos para a sua produção e utilização
KR20010029519A (ko) * 1996-09-19 2001-04-06 이곤 이 버그 요실금 치료 방법
AU4290099A (en) * 1998-06-29 2000-01-17 Mitsubishi-Tokyo Pharmaceuticals, Inc. Process for the preparation of optically active trans-cyclohexylamine compounds
DE19955190A1 (de) * 1999-11-16 2001-06-21 Sanol Arznei Schwarz Gmbh Stabile Salze neuartiger Derivate von 3,3-Diphenylpropylaminen
DE10332486A1 (de) * 2003-07-16 2005-02-10 Boehringer Ingelheim Pharma Gmbh & Co. Kg Ambroxol für die Behandlung akuter Schmerzen
WO2007073792A1 (de) * 2005-12-19 2007-07-05 Bayer Schering Pharma Aktiengesellschaft Verfahren zur herstellung von 4,4-diphenylcyclohexanol
DE102012106955B4 (de) * 2012-07-31 2014-04-03 Netzsch-Gerätebau GmbH Vorrichtung und Verfahren zur photothermischen Untersuchung einer Probe
CA3134613A1 (en) 2019-04-02 2020-10-08 Aligos Therapeutics, Inc. Compounds targeting prmt5
CN110963877B (zh) * 2019-12-18 2022-10-04 河北旭阳能源有限公司 1-氯-1-氯乙酰基环丙烷的制备方法

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3285960A (en) * 1964-01-14 1966-11-15 Cutter Lab 4, 4-diphenylcyclohexylamine derivatives
GB1102428A (en) * 1964-10-26 1968-02-07 Ciba Ltd Cycloaliphatic amines and process for their manufacture
DE1793611B2 (de) * 1964-12-15 1973-06-07 Merck Patent Gmbh, 6100 Darmstadt 4,4-diphenylcyclohexylamine, ihre saeureadditionssalze und quartaeren ammoniumsalze
GB1051280A (de) * 1964-12-15
AT273065B (de) * 1964-12-15 1969-07-25 Merck Ag E Verfahren zur Herstellung neuer Säureadditionssalze von 4,4-Diphenyl-cyclohexylaminen
US3479352A (en) * 1966-05-23 1969-11-18 Monsanto Co Trichloromethyl-tertiary amino substituted cycloalkenes and their preparation
US4141993A (en) * 1971-06-11 1979-02-27 Astra Lakemedel Aktiebolaget Compounds of diphenylcyclopentylamine type and methods for their preparation
NL7207811A (de) * 1971-06-11 1972-12-13
JPS608606B2 (ja) * 1975-07-02 1985-03-04 富士写真フイルム株式会社 強磁性粉末の製法
SE7703427L (sv) 1977-03-25 1978-09-26 Astra Laekemedel Ab Nya cykloalkylaminer
JPS57144247A (en) * 1981-03-02 1982-09-06 Lion Corp Preparation of n-substituted amino-alcohol compound
JPS6354351A (ja) * 1986-08-25 1988-03-08 Kanegafuchi Chem Ind Co Ltd 光学活性１−メチル−３−フエニルプロピルアジド及びその化合物を用いる光学活性アミンの製造法

Also Published As

Publication number Publication date
HU910748D0 (en) 1991-09-30
CA2037721A1 (en) 1991-09-09
DE69120699T2 (de) 1997-01-09
AU7266291A (en) 1991-09-12
HU211519A9 (en) 1995-11-28
NO910904L (no) 1991-09-09
EP0445749B1 (de) 1996-07-10
HUT60710A (en) 1992-10-28
FI911138A0 (fi) 1991-03-07
IE910752A1 (en) 1991-09-11
JPH04234832A (ja) 1992-08-24
NO175679C (no) 1994-11-16
NO175679B (no) 1994-08-08
JPH0819058B2 (ja) 1996-02-28
FI911138A (fi) 1991-09-09
ATE140213T1 (de) 1996-07-15
NO910904D0 (no) 1991-03-07
AU645062B2 (en) 1994-01-06
EP0445749A1 (de) 1991-09-11
CN1054586A (zh) 1991-09-18
KR910016691A (ko) 1991-11-05
US5256824A (en) 1993-10-26
PT96967A (pt) 1991-10-31

Similar Documents

Publication Publication Date Title
ATE25974T1 (de) Acyl-substituierte derivate von 1,2,3,4tetrahydroisochinolin-3-carboxysaeuren, ihre salze, diese enthaltende arzneimittel und verfahren zu ihrer herstellung.
DE69110625D1 (de) Oxazolopyridinderivate, Verfahren zu ihrer Herstellung und die sie enthaltenden pharmazeutischen Zusammensetzungen.
CA2334773A1 (en) Benzothiepine-1,1-dioxide derivatives, method for producing them, medicaments containing these compounds and their use
ATE128458T1 (de) Naphtylalkylamine, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische zusammensetzungen.
ATE174920T1 (de) Pyridothiadiazine, verfahren zu ihrer herstellung und sie enthaltende pharmazeutische zusammensetzungen
ATE156829T1 (de) Substituierte aminophosphonatderivate, verfahren zu ihrer herstellung und sie enthaltende pharmazeutische zusammensetzungen
DE69120699D1 (de) N-Monosubstituierte Cyclopentenylamine, ein Verfahren zu ihrer Herstellung, und ihre Verwendung als Medikament
ATE201024T1 (de) Carbamatderivate von 4-amino-3-isoxazolidinonen und 3-amino-1-hydroxypyrrolidinon-2-onen, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
DE68926981D1 (de) Cephemverbindungen und Verfahren zu ihrer Herstellung
ATE214051T1 (de) Substituierte tetrahydropyridinderivate, verfahren zu ihrer herstellung und diese enthaltende arzneimittel
AU3559793A (en) New 3-aminochroman spiro compounds, processes for their preparation and pharmaceutical compositions containing them
ZA933455B (en) Thiochroman compounds, processes for the preparation thereof and pharmaceutical compositions containing them
DE3781879D1 (de) Anthracyclinderivate, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel.
ATE168692T1 (de) 3-substituierte cephalosporine, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
DE69305330D1 (de) Aminoalkylchomone, Verfahren für ihre Herstellung und die enthaltende pharmazeutische Zusammensetzungen
ATE168371T1 (de) 5-amino-5,6,7,8-tetrahydrochinoline und verwandte verbindungen, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
NO903291L (no) Renin-hemmende aminooligohydroksyderivater.
ATE28647T1 (de) Chinazolinonderivate, verfahren zu ihrer herstellung und ihre verwendung in arzneimitteln.
ATE43586T1 (de) Arphameninderivate, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel.
DE69322218D1 (de) Heteroarenylpiperazine, Verfahren zu ihrer Herstellung und ihre Anwendung als Medikamente
AU659738B2 (en) New pyrrolothienopyrazine compounds, processes for the preparation thereof, and pharmaceutical compositions containing them
GR3021200T3 (en) (Cyclohexyl)-alken compounds, process for their preparation and pharmaceutical compositions containing them.
ATE49003T1 (de) Pregnane derivate, verfahren zu ihrer herstellung und pharmazeutische zusammenstellungen, die sie enthalten.
DE59201085D1 (de) Neue p-Oxibenzoesäurederivate, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel.
ATE85609T1 (de) S-difluoromethylhomocysteine, verfahren zu ihrer herstellung und insektizide zusammensetzungen.

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee