DE69117572T2 - Verfahren und Vorrichtung zum Erzeugen und Ermitteln einer Agglomerationsreaktion in einer flüssigen Probe - Google Patents
Verfahren und Vorrichtung zum Erzeugen und Ermitteln einer Agglomerationsreaktion in einer flüssigen ProbeInfo
- Publication number
- DE69117572T2 DE69117572T2 DE69117572T DE69117572T DE69117572T2 DE 69117572 T2 DE69117572 T2 DE 69117572T2 DE 69117572 T DE69117572 T DE 69117572T DE 69117572 T DE69117572 T DE 69117572T DE 69117572 T2 DE69117572 T2 DE 69117572T2
- Authority
- DE
- Germany
- Prior art keywords
- generating
- determining
- liquid sample
- agglomeration reaction
- agglomeration
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/75—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
- G01N21/77—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
- G01N21/82—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator producing a precipitate or turbidity
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/808—Optical sensing apparatus
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/805—Optical property
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Molecular Biology (AREA)
- Urology & Nephrology (AREA)
- Physics & Mathematics (AREA)
- Pathology (AREA)
- Analytical Chemistry (AREA)
- General Physics & Mathematics (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Cell Biology (AREA)
- Medicinal Chemistry (AREA)
- Food Science & Technology (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Plasma & Fusion (AREA)
- Investigating Or Analysing Materials By Optical Means (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP10932890A JP2675895B2 (ja) | 1990-04-25 | 1990-04-25 | 検体処理方法及び検体測定方法及び検体測定装置 |
JP2143729A JPH0436637A (ja) | 1990-05-31 | 1990-05-31 | 検体測定方法及び検体測定装置 |
JP17884390A JPH0466873A (ja) | 1990-07-06 | 1990-07-06 | 検体処理方法及び検体測定方法及び検体測定装置 |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69117572D1 DE69117572D1 (de) | 1996-04-11 |
DE69117572T2 true DE69117572T2 (de) | 1996-09-26 |
Family
ID=27311441
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69117572T Expired - Fee Related DE69117572T2 (de) | 1990-04-25 | 1991-04-24 | Verfahren und Vorrichtung zum Erzeugen und Ermitteln einer Agglomerationsreaktion in einer flüssigen Probe |
Country Status (3)
Country | Link |
---|---|
US (1) | US5198369A (de) |
EP (1) | EP0455125B1 (de) |
DE (1) | DE69117572T2 (de) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE102008034089A1 (de) * | 2008-07-21 | 2010-01-28 | Universität Bielefeld | Verfahren und Vorrichtung zur Messung der Kraft, die auf ein in einer optischen Fallenanordnung gefangenes Objekt wirkt |
Families Citing this family (65)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5286452A (en) * | 1991-05-20 | 1994-02-15 | Sienna Biotech, Inc. | Simultaneous multiple assays |
US5495105A (en) * | 1992-02-20 | 1996-02-27 | Canon Kabushiki Kaisha | Method and apparatus for particle manipulation, and measuring apparatus utilizing the same |
JPH05340865A (ja) * | 1992-06-09 | 1993-12-24 | Canon Inc | 測定装置 |
JP3292515B2 (ja) * | 1992-09-07 | 2002-06-17 | オリンパス光学工業株式会社 | 顕微鏡観察のための微調整方法及び微調整装置 |
FR2712977B1 (fr) * | 1993-11-24 | 1996-01-26 | Sematech Sarl | Détecteur d'itensité lumineuse diffusée par des objets submicroniques en concentration élevée. |
US5637458A (en) * | 1994-07-20 | 1997-06-10 | Sios, Inc. | Apparatus and method for the detection and assay of organic molecules |
FI98765C (fi) * | 1995-01-16 | 1997-08-11 | Erkki Soini | Virtaussytometrinen menetelmä ja laite |
AUPN968996A0 (en) * | 1996-05-06 | 1996-05-30 | Vision Products Pty Ltd | Filter integrity monitoring system |
AUPN968896A0 (en) * | 1996-05-06 | 1996-05-30 | Vision Products Pty Ltd | Optical scatter dectector controlling circuit and method |
US5940178A (en) * | 1996-07-03 | 1999-08-17 | Beckman Instruments, Inc. | Nephelometer and turbidimeter combination |
US5844685A (en) * | 1996-07-30 | 1998-12-01 | Bayer Corporation | Reference laser beam sampling apparatus |
ES2328423T3 (es) * | 1996-07-30 | 2009-11-12 | Siemens Healthcare Diagnostics Inc. | Sistema optico para un instrumento de hematologia analitica. |
AU5054198A (en) * | 1996-12-03 | 1998-06-29 | Erkki Soini | Biospecific, two photon excitation, fluorescence detection and device |
US5956139A (en) * | 1997-08-04 | 1999-09-21 | Ohio Aerospace Institute | Cross-correlation method and apparatus for suppressing the effects of multiple scattering |
DE19757785B4 (de) * | 1997-12-28 | 2005-09-01 | Günter Prof. Dr. Fuhr | Verfahren zur Bestimmung optisch induzierter Kräfte |
US6267722B1 (en) | 1998-02-03 | 2001-07-31 | Adeza Biomedical Corporation | Point of care diagnostic systems |
US6055106A (en) * | 1998-02-03 | 2000-04-25 | Arch Development Corporation | Apparatus for applying optical gradient forces |
US6394952B1 (en) * | 1998-02-03 | 2002-05-28 | Adeza Biomedical Corporation | Point of care diagnostic systems |
USD432244S (en) * | 1998-04-20 | 2000-10-17 | Adeza Biomedical Corporation | Device for encasing an assay test strip |
USD434153S (en) * | 1998-04-20 | 2000-11-21 | Adeza Biomedical Corporation | Point of care analyte detector system |
GB9816088D0 (en) * | 1998-07-23 | 1998-09-23 | Axis Biochemicals Asa | System |
EP1102059B1 (de) * | 1999-11-18 | 2005-10-05 | Matsushita Electric Industrial Co., Ltd. | Verfahren und Vorrichtung zur Messung von Streulicht |
US6570177B1 (en) * | 2000-01-31 | 2003-05-27 | Dcs Corporation | System, apparatus, and method for detecting defects in particles |
AU785424B2 (en) * | 2000-07-26 | 2007-05-17 | Regents Of The University Of California, The | Manipulation of live cells and inorganic objects with optical micro beam arrays |
AU2001290197A1 (en) * | 2000-10-05 | 2002-04-15 | Yoram Palti | Geometrically efficient particle agglutination, particularly to detect low affinity binding |
US6833542B2 (en) * | 2000-11-13 | 2004-12-21 | Genoptix, Inc. | Method for sorting particles |
US20020160470A1 (en) * | 2000-11-13 | 2002-10-31 | Genoptix | Methods and apparatus for generating and utilizing linear moving optical gradients |
US6784420B2 (en) * | 2000-11-13 | 2004-08-31 | Genoptix, Inc. | Method of separating particles using an optical gradient |
US20020123112A1 (en) * | 2000-11-13 | 2002-09-05 | Genoptix | Methods for increasing detection sensitivity in optical dielectric sorting systems |
US6936811B2 (en) * | 2000-11-13 | 2005-08-30 | Genoptix, Inc. | Method for separating micro-particles |
US20030007894A1 (en) * | 2001-04-27 | 2003-01-09 | Genoptix | Methods and apparatus for use of optical forces for identification, characterization and/or sorting of particles |
US6744038B2 (en) | 2000-11-13 | 2004-06-01 | Genoptix, Inc. | Methods of separating particles using an optical gradient |
US6778724B2 (en) * | 2000-11-28 | 2004-08-17 | The Regents Of The University Of California | Optical switching and sorting of biological samples and microparticles transported in a micro-fluidic device, including integrated bio-chip devices |
AU2002251449B2 (en) * | 2001-03-29 | 2008-01-31 | Cellect Technologies Corp. | Methods devices and systems for sorting and separating particles |
US6416190B1 (en) * | 2001-04-27 | 2002-07-09 | University Of Chicago | Apparatus for using optical tweezers to manipulate materials |
US20040009540A1 (en) * | 2001-04-27 | 2004-01-15 | Genoptix, Inc | Detection and evaluation of cancer cells using optophoretic analysis |
US20030194755A1 (en) * | 2001-04-27 | 2003-10-16 | Genoptix, Inc. | Early detection of apoptotic events and apoptosis using optophoretic analysis |
CN1854778A (zh) | 2001-06-20 | 2006-11-01 | 阿尔利克斯公司 | 光开关和光路由器以及光滤波器 |
US20030211461A1 (en) * | 2002-05-01 | 2003-11-13 | Genoptix, Inc | Optophoretic detection of durgs exhibiting inhibitory effect on Bcr-Abl positive tumor cells |
US20040033539A1 (en) * | 2002-05-01 | 2004-02-19 | Genoptix, Inc | Method of using optical interrogation to determine a biological property of a cell or population of cells |
US6870610B1 (en) | 2002-05-07 | 2005-03-22 | Dcs Corporation | Method and apparatus for detecting defects in a material in a liquid bath |
JP4299597B2 (ja) | 2002-07-29 | 2009-07-22 | シスメックス株式会社 | 血液分析装置及び方法 |
US20040053209A1 (en) * | 2002-09-12 | 2004-03-18 | Genoptix, Inc | Detection and evaluation of topoisomerase inhibitors using optophoretic analysis |
US20040067167A1 (en) * | 2002-10-08 | 2004-04-08 | Genoptix, Inc. | Methods and apparatus for optophoretic diagnosis of cells and particles |
US20040121307A1 (en) * | 2002-12-19 | 2004-06-24 | Genoptix, Inc | Early detection of cellular differentiation using optophoresis |
US20040121474A1 (en) * | 2002-12-19 | 2004-06-24 | Genoptix, Inc | Detection and evaluation of chemically-mediated and ligand-mediated t-cell activation using optophoretic analysis |
JP4533044B2 (ja) * | 2003-08-27 | 2010-08-25 | キヤノン株式会社 | センサ |
AU2004269406B2 (en) * | 2003-08-28 | 2010-12-16 | Progenity, Inc. | Methods and apparatus for sorting cells using an optical switch in a microfluidic channel network |
US7658884B2 (en) * | 2005-10-05 | 2010-02-09 | Swan Analytische Instrumente Ag | Photometric method and apparatus for measuring a liquid's turbidity, fluorescence, phosphorescence and/or absorption coefficient |
EP1826705A1 (de) * | 2006-02-25 | 2007-08-29 | F.Hoffmann-La Roche Ag | Analytisches Verbrauchsmittel und Anordnung zum Auslesen von Informationen |
US8789756B2 (en) * | 2006-02-25 | 2014-07-29 | Roche Diagnostics Operations, Inc. | Test element coding apparatuses, systems and methods |
US8169600B2 (en) * | 2006-09-15 | 2012-05-01 | Arryx, Inc. | Surface mapping by optical manipulation of particles in relation to a functionalized surface |
KR100922577B1 (ko) * | 2007-12-13 | 2009-10-23 | 한국전자통신연구원 | 휴대형 광바이오 센서 측정 시스템 |
WO2009088492A1 (en) * | 2008-01-04 | 2009-07-16 | The Government Of The United States Of America, As Represented By The Secretary Of The Navy Naval | Optical separator and method for separating particles suspended in a fluid |
WO2009108921A2 (en) * | 2008-02-28 | 2009-09-03 | Lehigh University | Opto-fluidic nanoparticle detection apparatus |
DE102008035933A1 (de) * | 2008-07-31 | 2010-02-04 | Carl Zeiss Microlmaging Gmbh | Vorrichtung zum Halten und Positionieren einer Probe relativ zu einem Mikroskopobjektiv |
US8422740B2 (en) | 2009-01-15 | 2013-04-16 | Scott Dylewski | Methods for determining a liquid front position on a test strip |
US8692873B2 (en) | 2009-01-15 | 2014-04-08 | Alverix, Inc. | Video-frame data receiver with low frame capture rate |
ES2387368B1 (es) | 2009-05-15 | 2013-08-08 | Universidad De Barcelona | Metodo y aparato de medida de las fuerzas opticas que actuan sobre una particula |
US10295472B2 (en) | 2010-05-05 | 2019-05-21 | Alverix, Inc. | Assay reader operable to scan a test strip |
JP5662742B2 (ja) * | 2010-08-27 | 2015-02-04 | アイステーシス株式会社 | 粒径計測装置及び粒径計測方法 |
CN102540447B (zh) * | 2012-02-17 | 2014-06-11 | 中国科学技术大学 | 一种俘获及探测复用的扫描光镊系统 |
EP2993460B1 (de) * | 2013-05-30 | 2019-07-03 | Osaka Prefecture University Public Corporation | Zielsubstanzdetektionsvorrichtung und -verfahren |
WO2016143083A1 (ja) * | 2015-03-10 | 2016-09-15 | 技術研究組合次世代3D積層造形技術総合開発機構 | 光加工ヘッド、光加工装置およびその制御方法ならびに制御プログラム |
EP4024030A4 (de) * | 2019-08-30 | 2023-09-13 | University Public Corporation Osaka | Detektionsverfahren für zu detektierende substanz und detektionssystem für zu detektierende substanz |
Family Cites Families (18)
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US3088875A (en) * | 1959-10-27 | 1963-05-07 | Hyland Lab | Immunological diagnostics utilizing polystyrene latex particles of 0.15 to 0.25 micron |
US3710279A (en) * | 1969-12-15 | 1973-01-09 | Bell Telephone Labor Inc | Apparatuses for trapping and accelerating neutral particles |
US3808550A (en) * | 1969-12-15 | 1974-04-30 | Bell Telephone Labor Inc | Apparatuses for trapping and accelerating neutral particles |
JPS5811575B2 (ja) * | 1976-08-16 | 1983-03-03 | 帝国臓器製薬株式会社 | 抗原−抗体反応の測定法 |
JPS54108694A (en) * | 1978-02-14 | 1979-08-25 | Mitsubishi Chem Ind | Method of measuring antigennantibody reaction |
JPS54108695A (en) * | 1978-02-15 | 1979-08-25 | Teikoku Hormone Mfg Co Ltd | Method and device for measuring antigennantibody reaction |
JPS54108693A (en) * | 1978-02-14 | 1979-08-25 | Mitsubishi Chem Ind | Method and device for optically measuring antigennantibody reaction |
JPS54109494A (en) * | 1978-02-16 | 1979-08-28 | Teikoku Hormone Mfg Co Ltd | Method of measuring antigennantibody reaction |
JPS55159157A (en) * | 1979-05-31 | 1980-12-11 | Mitsubishi Chem Ind Ltd | Quantitative determining method of antigen or antibody |
JPS58187860A (ja) * | 1982-04-26 | 1983-11-02 | Wako Pure Chem Ind Ltd | 免疫学的凝集反応の光学的測定方法 |
US4537861A (en) * | 1983-02-03 | 1985-08-27 | Elings Virgil B | Apparatus and method for homogeneous immunoassay |
JPS59187264A (ja) * | 1983-03-30 | 1984-10-24 | Kyowa Hakko Kogyo Co Ltd | 抗原−抗体反応速度の測定法 |
JPS6086468A (ja) * | 1983-10-18 | 1985-05-16 | Olympus Optical Co Ltd | 抗原抗体反応の判定方法 |
JPS60256443A (ja) * | 1984-05-31 | 1985-12-18 | オムロン株式会社 | 画像計測装置 |
US4762413A (en) * | 1984-09-07 | 1988-08-09 | Olympus Optical Co., Ltd. | Method and apparatus for measuring immunological reaction with the aid of fluctuation in intensity of scattered light |
US4893886A (en) * | 1987-09-17 | 1990-01-16 | American Telephone And Telegraph Company | Non-destructive optical trap for biological particles and method of doing same |
US4887721A (en) * | 1987-11-30 | 1989-12-19 | The United States Of America As Represented By The United States Department Of Energy | Laser particle sorter |
US4920275A (en) * | 1988-12-30 | 1990-04-24 | Canon Kabushiki Kaisha | Particle measuring device with elliptically-shaped scanning beam |
-
1991
- 1991-04-19 US US07/687,627 patent/US5198369A/en not_active Expired - Fee Related
- 1991-04-24 EP EP91106608A patent/EP0455125B1/de not_active Expired - Lifetime
- 1991-04-24 DE DE69117572T patent/DE69117572T2/de not_active Expired - Fee Related
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE102008034089A1 (de) * | 2008-07-21 | 2010-01-28 | Universität Bielefeld | Verfahren und Vorrichtung zur Messung der Kraft, die auf ein in einer optischen Fallenanordnung gefangenes Objekt wirkt |
Also Published As
Publication number | Publication date |
---|---|
EP0455125B1 (de) | 1996-03-06 |
EP0455125A2 (de) | 1991-11-06 |
EP0455125A3 (en) | 1992-07-01 |
DE69117572D1 (de) | 1996-04-11 |
US5198369A (en) | 1993-03-30 |
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Legal Events
Date | Code | Title | Description |
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8364 | No opposition during term of opposition | ||
8328 | Change in the person/name/address of the agent |
Free format text: WESER & KOLLEGEN, 81245 MUENCHEN |
|
8339 | Ceased/non-payment of the annual fee |