DE69114210D1 - Carbamoyl-1-(pyridinylalkyl)-1H-indole, -indoline und verwandte Verbindungen. - Google Patents

Carbamoyl-1-(pyridinylalkyl)-1H-indole, -indoline und verwandte Verbindungen.

Info

Publication number
DE69114210D1
DE69114210D1 DE69114210T DE69114210T DE69114210D1 DE 69114210 D1 DE69114210 D1 DE 69114210D1 DE 69114210 T DE69114210 T DE 69114210T DE 69114210 T DE69114210 T DE 69114210T DE 69114210 D1 DE69114210 D1 DE 69114210D1
Authority
DE
Germany
Prior art keywords
loweralkyl
hydrogen
arylloweralkyl
chem
aryl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69114210T
Other languages
English (en)
Other versions
DE69114210T2 (de
Inventor
Richard Charles Effland
Larry Davis
Gordon E Olsen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Aventis Pharmaceuticals Inc
Original Assignee
Hoechst Roussel Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Roussel Pharmaceuticals Inc filed Critical Hoechst Roussel Pharmaceuticals Inc
Publication of DE69114210D1 publication Critical patent/DE69114210D1/de
Application granted granted Critical
Publication of DE69114210T2 publication Critical patent/DE69114210T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Neurosurgery (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Hospice & Palliative Care (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Psychiatry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Indole Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DE69114210T 1990-08-13 1991-08-08 Carbamoyl-1-(pyridinylalkyl)-1H-indole, -indoline und verwandte Verbindungen. Expired - Fee Related DE69114210T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US56672490A 1990-08-13 1990-08-13

Publications (2)

Publication Number Publication Date
DE69114210D1 true DE69114210D1 (de) 1995-12-07
DE69114210T2 DE69114210T2 (de) 1996-05-02

Family

ID=24264113

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69114210T Expired - Fee Related DE69114210T2 (de) 1990-08-13 1991-08-08 Carbamoyl-1-(pyridinylalkyl)-1H-indole, -indoline und verwandte Verbindungen.

Country Status (20)

Country Link
EP (1) EP0471298B1 (de)
JP (1) JPH0670034B2 (de)
KR (1) KR100215156B1 (de)
AT (1) ATE129710T1 (de)
AU (1) AU638158B2 (de)
CA (1) CA2048931C (de)
CZ (1) CZ284753B6 (de)
DE (1) DE69114210T2 (de)
DK (1) DK0471298T3 (de)
ES (1) ES2079532T3 (de)
FI (1) FI104554B (de)
GR (1) GR3018068T3 (de)
HU (1) HUT58723A (de)
IE (1) IE69968B1 (de)
IL (1) IL99167A (de)
MX (1) MX9100640A (de)
NO (1) NO178372C (de)
NZ (1) NZ239327A (de)
PT (1) PT98646B (de)
ZA (1) ZA916340B (de)

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE787444A (fr) * 1971-08-13 1973-02-12 Hoffmann La Roche Composes polycycliques
GB2102795A (en) * 1981-07-31 1983-02-09 Pfizer Ltd Indole derivatives
FR2591595B1 (fr) * 1985-12-13 1988-09-09 Roussel Uclaf Nouveaux derives du 4-morpholinyl 1h-indole, leurs sels, procede de preparation, application a titre de medicaments, compositions les renfermant, et intermediaires
DE3809155A1 (de) * 1988-03-18 1989-09-28 Bayer Ag 1,3,4,5-tetrahydrobenz-(c,d)-indole
ATE130002T1 (de) * 1990-08-13 1995-11-15 Hoechst Roussel Pharma 1-(pyridinylalkyl)-1h-indole, -indoline und analoge.

Also Published As

Publication number Publication date
IE69968B1 (en) 1996-10-16
IL99167A (en) 1995-05-26
MX9100640A (es) 1992-04-01
EP0471298B1 (de) 1995-11-02
HU912675D0 (en) 1992-01-28
FI913801A (fi) 1992-02-14
GR3018068T3 (en) 1996-02-29
AU8176691A (en) 1992-02-20
HUT58723A (en) 1992-03-30
NO178372B (no) 1995-12-04
NZ239327A (en) 1994-07-26
EP0471298A1 (de) 1992-02-19
CZ284753B6 (cs) 1999-02-17
IL99167A0 (en) 1992-07-15
KR920004378A (ko) 1992-03-27
DK0471298T3 (da) 1996-03-04
CA2048931C (en) 2001-10-30
CA2048931A1 (en) 1992-02-14
IE912852A1 (en) 1992-02-26
KR100215156B1 (ko) 1999-08-16
NO913141L (no) 1992-02-14
FI913801A0 (fi) 1991-08-09
JPH05125075A (ja) 1993-05-21
FI104554B (fi) 2000-02-29
PT98646B (pt) 1999-01-29
PT98646A (pt) 1992-06-30
NO178372C (no) 1996-03-13
JPH0670034B2 (ja) 1994-09-07
ZA916340B (en) 1992-04-29
CS249091A3 (en) 1992-03-18
ES2079532T3 (es) 1996-01-16
DE69114210T2 (de) 1996-05-02
NO913141D0 (no) 1991-08-12
AU638158B2 (en) 1993-06-17
ATE129710T1 (de) 1995-11-15

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FI102067B (fi) Menetelmä terapeuttisesti käyttökelpoisten 1-(substituoitu pyridinyyli amino)-1H-indol-5-yyli-substituoitujen karbamaattien valmistamiseksi
DE69114404D1 (de) 1-(Pyridinylalkyl)-1H-indole, -indoline und Analoge.
DE69114210D1 (de) Carbamoyl-1-(pyridinylalkyl)-1H-indole, -indoline und verwandte Verbindungen.

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee