DE69109279D1 - Wässrige suspension als injektionszubereitung, verfahren zur herstellung derselben und verwendung für schmerzstillung. - Google Patents

Wässrige suspension als injektionszubereitung, verfahren zur herstellung derselben und verwendung für schmerzstillung.

Info

Publication number
DE69109279D1
DE69109279D1 DE69109279T DE69109279T DE69109279D1 DE 69109279 D1 DE69109279 D1 DE 69109279D1 DE 69109279 T DE69109279 T DE 69109279T DE 69109279 T DE69109279 T DE 69109279T DE 69109279 D1 DE69109279 D1 DE 69109279D1
Authority
DE
Germany
Prior art keywords
preparation
less
aqueous suspension
production
diameter
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69109279T
Other languages
English (en)
Other versions
DE69109279T2 (de
Inventor
Eric Ackerman
Rene Grouls
Hendrikus Korsten
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
CATHARINA ZIEKENHUIS STICHTING
Original Assignee
CATHARINA ZIEKENHUIS STICHTING
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by CATHARINA ZIEKENHUIS STICHTING filed Critical CATHARINA ZIEKENHUIS STICHTING
Publication of DE69109279D1 publication Critical patent/DE69109279D1/de
Application granted granted Critical
Publication of DE69109279T2 publication Critical patent/DE69109279T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/235—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group
    • A61K31/24—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group having an amino or nitro group
    • A61K31/245—Amino benzoic acid types, e.g. procaine, novocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P23/00—Anaesthetics
    • A61P23/02—Local anaesthetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Anesthesiology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurology (AREA)
  • Dermatology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Emergency Medicine (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
DE69109279T 1990-03-20 1991-03-20 Wässrige suspension als injektionszubereitung, verfahren zur herstellung derselben und verwendung für schmerzstillung. Expired - Fee Related DE69109279T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
NL9000634A NL9000634A (nl) 1990-03-20 1990-03-20 Suspensie-injectiepreparaat op waterbasis, werkwijze voor de bereiding daarvan en toepassing van dit preparaat voor pijnbestrijding.
PCT/NL1991/000042 WO1991014455A1 (en) 1990-03-20 1991-03-20 Aqueous suspension preparation for injection, method for producing the same and use thereof for producing pain relief

Publications (2)

Publication Number Publication Date
DE69109279D1 true DE69109279D1 (de) 1995-06-01
DE69109279T2 DE69109279T2 (de) 1995-11-09

Family

ID=19856770

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69109279T Expired - Fee Related DE69109279T2 (de) 1990-03-20 1991-03-20 Wässrige suspension als injektionszubereitung, verfahren zur herstellung derselben und verwendung für schmerzstillung.

Country Status (15)

Country Link
US (1) US5346903A (de)
EP (1) EP0521070B1 (de)
JP (1) JPH05507466A (de)
AT (1) ATE121631T1 (de)
AU (1) AU646857B2 (de)
BR (1) BR1100601A (de)
CA (1) CA2077641C (de)
DE (1) DE69109279T2 (de)
DK (1) DK0521070T3 (de)
ES (1) ES2074269T3 (de)
FI (1) FI98890C (de)
GR (1) GR3015940T3 (de)
NL (1) NL9000634A (de)
NO (1) NO300114B1 (de)
WO (1) WO1991014455A1 (de)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5206267A (en) * 1991-05-09 1993-04-27 Morton Shulman Pain controlling composition and method of preparation
US5635540A (en) * 1994-12-09 1997-06-03 The University Of Virginia Patent Foundation Stabilized topical pharmaceutical preparations
US6077545A (en) 1995-10-30 2000-06-20 Matrix Pharmaceuticals, Inc. Process and composition for therapeutic cisplatin (CDDP)
ES2341399T3 (es) * 1996-03-26 2010-06-18 Eli Lilly And Company Benziotofenos, formulaciones que contienen los mismos y procedimientos.
US6541021B1 (en) * 1999-03-18 2003-04-01 Durect Corporation Devices and methods for pain management
US6835194B2 (en) * 1999-03-18 2004-12-28 Durect Corporation Implantable devices and methods for treatment of pain by delivery of fentanyl and fentanyl congeners
US7074803B2 (en) * 2001-03-02 2006-07-11 Durect Corporation Opioid formulations
JP2004527573A (ja) * 2001-04-24 2004-09-09 パーデュー・リサーチ・ファウンデーション 哺乳類の神経組織損傷の治療のための方法及び組成物
AU2003211009A1 (en) * 2002-02-11 2003-09-04 Wake Forest University Compositions and methods for treating pain using cyclooxygenase-1 inhibitors
US7838034B2 (en) 2002-07-30 2010-11-23 Grunenthal Gmbh Intravenous pharmaceutical form of administration
DE10234784A1 (de) * 2002-07-30 2004-02-19 Günenthal GmbH Intravenös applizierbare, pharmazeutische Darreichungsform
US20040102476A1 (en) * 2002-11-25 2004-05-27 Chan Tai Wah High concentration formulations of opioids and opioid derivatives
JP4686361B2 (ja) * 2002-12-31 2011-05-25 アルタス ファーマシューティカルズ インコーポレイテッド ヒト成長ホルモンの結晶およびその調製方法
WO2004060920A1 (en) * 2002-12-31 2004-07-22 Altus Pharmaceuticals Inc. Complexes of protein crystals and ionic polymers
GB0300531D0 (en) 2003-01-10 2003-02-12 West Pharm Serv Drug Res Ltd Pharmaceutical compositions
WO2007076131A2 (en) * 2005-12-23 2007-07-05 Altus Pharmaceuticals Inc. Compositions comprising polycation-complexed protein crystals and methods of treatment using them
JP2010513309A (ja) * 2006-12-18 2010-04-30 アルタス ファーマシューティカルズ インコーポレイテッド ヒト成長ホルモン製剤
FI20075091A0 (fi) * 2007-02-09 2007-02-09 Kim Lemberg Noroksimorfoni käytettäväksi lääkeaineena
US20080227805A1 (en) * 2007-02-28 2008-09-18 Abbott Laboratories Sustained release parenteral formulations of buprenorphine
US9125867B2 (en) * 2010-02-24 2015-09-08 Invincible Biotechnology Diversion- and/or abuse-resistant compositions and methods for making the same
GB2513060B (en) * 2010-06-08 2015-01-07 Rb Pharmaceuticals Ltd Microparticle buprenorphine suspension
US9272044B2 (en) 2010-06-08 2016-03-01 Indivior Uk Limited Injectable flowable composition buprenorphine
GB201404139D0 (en) 2014-03-10 2014-04-23 Rb Pharmaceuticals Ltd Sustained release buprenorphine solution formulations
AU2015341490C1 (en) 2014-11-07 2021-03-11 Indivior Uk Limited Buprenorphine dosing regimens
US10646484B2 (en) 2017-06-16 2020-05-12 Indivior Uk Limited Methods to treat opioid use disorder
WO2022175977A1 (en) * 2021-02-18 2022-08-25 Navin Saxena Research And Technology Private Limited A biodegradable implant composition and process for long term delivery of buprenorphine and use thereof

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB784659A (en) * 1954-11-26 1957-10-16 Upjohn Co Therapeutic compositions and aqueous suspensions thereof
US3337406A (en) * 1963-12-12 1967-08-22 Mar Sal Inc Treatment of arteriosclerotic diseases
EP0031603A1 (de) * 1979-12-31 1981-07-08 American Cyanamid Company Pharmazeutische Zusammensetzung eines Grundstoffs
US4963367A (en) * 1984-04-27 1990-10-16 Medaphore, Inc. Drug delivery compositions and methods
US4599354A (en) * 1985-03-11 1986-07-08 Morton Shulman Composition and method for producing prolonged pain relief

Also Published As

Publication number Publication date
BR1100601A (pt) 2000-04-18
NO300114B1 (no) 1997-04-14
NO923429L (no) 1992-09-17
CA2077641C (en) 2001-07-03
JPH05507466A (ja) 1993-10-28
AU646857B2 (en) 1994-03-10
FI98890B (fi) 1997-05-30
EP0521070B1 (de) 1995-04-26
CA2077641A1 (en) 1991-09-21
WO1991014455A1 (en) 1991-10-03
FI924019A0 (fi) 1992-09-08
ATE121631T1 (de) 1995-05-15
AU7558091A (en) 1991-10-21
FI924019A (fi) 1992-09-08
NL9000634A (nl) 1991-10-16
GR3015940T3 (en) 1995-07-31
US5346903A (en) 1994-09-13
EP0521070A1 (de) 1993-01-07
NO923429D0 (no) 1992-09-03
FI98890C (fi) 1997-09-10
DE69109279T2 (de) 1995-11-09
DK0521070T3 (da) 1995-05-22
ES2074269T3 (es) 1995-09-01

Similar Documents

Publication Publication Date Title
DE69109279D1 (de) Wässrige suspension als injektionszubereitung, verfahren zur herstellung derselben und verwendung für schmerzstillung.
DE59502704D1 (de) Aerogelhaltige zusammensetzung, verfahren zur ihrer herstellung sowie ihre verwendung
ZA959386B (en) Small particle formation
FR2695558B1 (fr) Composition cosmétique contenant des particules solides revêtues avec un polymère amphotère.
JPS55147228A (en) Fat emulsion for intravenous injection
DE59505985D1 (de) Aerogelhaltiges verbundmaterial, verfahren zu seiner herstellung sowie seine verwendung
ATE59287T1 (de) Verfahren zur herstellung einer auf der stelle zubereitbaren homogenen mikrokapselsuspension.
DE69706988D1 (de) Verfahren zur lieferung von zusammensetzungen aus dichten teilchen zur anwendung in transdermale teilchen abgabe
ATE150310T1 (de) Oral anzuwendende suspension bestehend aus stabilisiertem rockenpulver eines hydratisierten cephalosporins
Jaurand et al. Effect of chrysotile and crocidolite on the morphology and growth of rat pleural mesothelial cells
GB2232591B (en) Toothpaste composition comprising tripolyphosphate salt
DE3855121T2 (de) Anxiolytisch wirksame Piperazinderivate
EP0135189A3 (de) Pharmazeutisch verwendbare Malonamide
ATE218510T1 (de) Verfahren zur herstellung eines titansilikates mit rut-struktur
NZ509881A (en) Micronised pharmaceutical compositions containing colistin sulphomethate sodium
Kretz et al. Differentialindikation von Halothan, Enfluran und Isofluran in der Kinderanästhesie
Suh et al. Analgesic Effects of Epidural Clonidine
DE2614503A1 (de) Verfahren zur herstellung einer fuer die intravenoese anwendung geeigneten gammaglobulinloesung
KR890014115A (ko) 4-(3-포스포노-2-프로페닐)-2-피페라진카르복실산의 신규한 용도
JPH08157351A (ja) 入浴剤
JPS57197220A (en) Muscle relaxant
SU1775897A1 (ru) Способ получения диагностического агента для определения протромбинового времени
ATE7893T1 (de) 10b-carboxy-aminoborane, verfahren zur herstellung derselben sowie ihre verwendung als arzneimittel zur neutroneneinfangtherapie.

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee