DE69100598D1 - Verfahren zur Herstellung eines optisch aktiven Aminosäureamids. - Google Patents

Verfahren zur Herstellung eines optisch aktiven Aminosäureamids.

Info

Publication number
DE69100598D1
DE69100598D1 DE91200306T DE69100598T DE69100598D1 DE 69100598 D1 DE69100598 D1 DE 69100598D1 DE 91200306 T DE91200306 T DE 91200306T DE 69100598 T DE69100598 T DE 69100598T DE 69100598 D1 DE69100598 D1 DE 69100598D1
Authority
DE
Germany
Prior art keywords
amino acid
optically active
acid amide
preparation
mixture
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE91200306T
Other languages
English (en)
Other versions
DE69100598T2 (de
Inventor
Wilhelmus Hubertus Jos Boesten
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
DSM IP Assets BV
Original Assignee
DSM NV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by DSM NV filed Critical DSM NV
Publication of DE69100598D1 publication Critical patent/DE69100598D1/de
Application granted granted Critical
Publication of DE69100598T2 publication Critical patent/DE69100598T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C231/00—Preparation of carboxylic acid amides
    • C07C231/16—Preparation of optical isomers
    • C07C231/20—Preparation of optical isomers by separation of optical isomers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B57/00—Separation of optically-active compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C237/20—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton containing six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C249/00—Preparation of compounds containing nitrogen atoms doubly-bound to a carbon skeleton
    • C07C249/02—Preparation of compounds containing nitrogen atoms doubly-bound to a carbon skeleton of compounds containing imino groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C319/00—Preparation of thiols, sulfides, hydropolysulfides or polysulfides
    • C07C319/26—Separation; Purification; Stabilisation; Use of additives
    • C07C319/28—Separation; Purification

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DE69100598T 1990-02-16 1991-02-14 Verfahren zur Herstellung eines optisch aktiven Aminosäureamids. Expired - Fee Related DE69100598T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
NL9000386A NL9000386A (nl) 1990-02-16 1990-02-16 Werkwijze voor de bereiding van optisch aktief aminozuuramide.
SG13294A SG13294G (en) 1990-02-16 1994-01-26 Process for the preparation of an optically active amino acid amide.

Publications (2)

Publication Number Publication Date
DE69100598D1 true DE69100598D1 (de) 1993-12-16
DE69100598T2 DE69100598T2 (de) 1994-05-19

Family

ID=26646659

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69100598T Expired - Fee Related DE69100598T2 (de) 1990-02-16 1991-02-14 Verfahren zur Herstellung eines optisch aktiven Aminosäureamids.

Country Status (12)

Country Link
US (1) US5306826A (de)
EP (1) EP0442584B1 (de)
JP (1) JP2854148B2 (de)
KR (1) KR0179028B1 (de)
AT (1) ATE97125T1 (de)
CZ (1) CZ281203B6 (de)
DE (1) DE69100598T2 (de)
DK (1) DK0442584T3 (de)
ES (1) ES2062660T3 (de)
HU (1) HU212703B (de)
NL (1) NL9000386A (de)
SG (1) SG13294G (de)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5346653A (en) * 1991-02-18 1994-09-13 Matsushita Electric Industrial Co., Ltd. Non-linear optical material, method of manufacturing the same and optical wavelength converter
NL9201230A (nl) * 1992-07-09 1994-02-01 Dsm Nv Werkwijze voor de bereiding van optisch aktief methionineamide.
US5495012A (en) * 1992-12-28 1996-02-27 Tanabe Seiyaku Co., Ltd. Process for preparing optically active 4-mercapto-2-pyrrolidone derivative and intermediate therefor
JP2701685B2 (ja) * 1992-12-28 1998-01-21 田辺製薬株式会社 光学活性４−メルカプト−２−ピロリドン誘導体及びその合成中間体の製法
BE1007296A3 (nl) * 1993-07-19 1995-05-09 Dsm Nv Werkwijze voor de bereiding van een beta-lactamderivaat.
JPH08157437A (ja) * 1994-12-08 1996-06-18 Ajinomoto Co Inc Ｄ−アミノ酸−Ｎ−（Ｓ）−α−アルキルベンジルアミドの製造法
BE1010647A3 (nl) * 1996-09-24 1998-11-03 Dsm Nv Werkwijze voor de bereiding van een anorganisch zout van een optisch aktief fenylglycinederivaat.
SE0100902D0 (sv) 2001-03-15 2001-03-15 Astrazeneca Ab Compounds
SE0202539D0 (sv) 2002-08-27 2002-08-27 Astrazeneca Ab Compounds
SE0401762D0 (sv) 2004-07-05 2004-07-05 Astrazeneca Ab Novel compounds
US7648992B2 (en) 2004-07-05 2010-01-19 Astrazeneca Ab Hydantoin derivatives for the treatment of obstructive airway diseases
SE0403085D0 (sv) 2004-12-17 2004-12-17 Astrazeneca Ab Novel componds
SE0403086D0 (sv) 2004-12-17 2004-12-17 Astrazeneca Ab Compounds
TW200800954A (en) * 2006-03-16 2008-01-01 Astrazeneca Ab Novel crystal modifications
TW200831488A (en) 2006-11-29 2008-08-01 Astrazeneca Ab Novel compounds
CN102952029B (zh) * 2011-09-30 2015-07-08 北京海步国际医药科技发展有限公司 将苄胺衍生物用于拆分2-羟基-3-甲氧基-3,3-二-苯基丙酸消旋物及拆分方法
KR102055702B1 (ko) * 2017-12-12 2019-12-13 주식회사 아미노로직스 광학 활성을 가진 2-옥틸글리신 에스터를 제조하는 방법

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE795874A (fr) * 1972-02-25 1973-08-23 Glaxo Lab Ltd Procede de preparation d'esters optiquement actifs d'alpha-amino-acides
NL7514300A (nl) * 1975-12-09 1977-06-13 Stamicarbon Werkwijze voor de bereiding van optisch actief fenylglycineamide.
US4072698A (en) * 1976-12-02 1978-02-07 The Upjohn Company Resolution of aminonitriles
DE2749203C2 (de) * 1977-11-03 1981-12-17 Riedel-De Haen Ag, 3016 Seelze Verfahren zur Racematspaltung von DL-alpha-Aminocarbonsäuren und diastereomere Salze
FR2430413A1 (fr) * 1978-07-07 1980-02-01 Anvar Procede de preparation d'alpha-aminoacides optiquement actifs, et leurs derives

Also Published As

Publication number Publication date
SG13294G (en) 1994-06-10
CS9100418A2 (en) 1991-09-15
JPH05178805A (ja) 1993-07-20
DE69100598T2 (de) 1994-05-19
ATE97125T1 (de) 1993-11-15
KR0179028B1 (ko) 1999-05-15
HU910482D0 (en) 1991-08-28
CZ281203B6 (cs) 1996-07-17
US5306826A (en) 1994-04-26
EP0442584A1 (de) 1991-08-21
KR910021368A (ko) 1991-12-20
NL9000386A (nl) 1991-09-16
EP0442584B1 (de) 1993-11-10
JP2854148B2 (ja) 1999-02-03
ES2062660T3 (es) 1994-12-16
DK0442584T3 (da) 1994-03-07
HUT56532A (en) 1991-09-30
HU212703B (en) 1996-10-28

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: DSM IP ASSETS B.V., HEERLEN, NL

8339 Ceased/non-payment of the annual fee