DE69031669T2 - Substituierte Sulfonamide und verwandte Verbindungen zur Behandlung von Asthma, Arthritis und verwandten Krankheiten - Google Patents

Substituierte Sulfonamide und verwandte Verbindungen zur Behandlung von Asthma, Arthritis und verwandten Krankheiten

Info

Publication number
DE69031669T2
DE69031669T2 DE69031669T DE69031669T DE69031669T2 DE 69031669 T2 DE69031669 T2 DE 69031669T2 DE 69031669 T DE69031669 T DE 69031669T DE 69031669 T DE69031669 T DE 69031669T DE 69031669 T2 DE69031669 T2 DE 69031669T2
Authority
DE
Germany
Prior art keywords
asthma
arthritis
treatment
substituted sulfonamides
compounds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69031669T
Other languages
English (en)
Other versions
DE69031669D1 (de
Inventor
James F Eggler
Hiroko Masamune
Anthony Marfat
Lawrence S Melvin
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Inc
Original Assignee
Pfizer Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Inc filed Critical Pfizer Inc
Publication of DE69031669D1 publication Critical patent/DE69031669D1/de
Application granted granted Critical
Publication of DE69031669T2 publication Critical patent/DE69031669T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/08Bronchodilators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Cardiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Quinoline Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Cephalosporin Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DE69031669T 1989-06-22 1990-06-14 Substituierte Sulfonamide und verwandte Verbindungen zur Behandlung von Asthma, Arthritis und verwandten Krankheiten Expired - Fee Related DE69031669T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US1989/002748 WO1990015801A1 (en) 1989-06-22 1989-06-22 Substituted sulfonamides and related compounds in the treatment of asthma, arthritis and related diseases

Publications (2)

Publication Number Publication Date
DE69031669D1 DE69031669D1 (de) 1997-12-11
DE69031669T2 true DE69031669T2 (de) 1998-03-05

Family

ID=22215089

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69031669T Expired - Fee Related DE69031669T2 (de) 1989-06-22 1990-06-14 Substituierte Sulfonamide und verwandte Verbindungen zur Behandlung von Asthma, Arthritis und verwandten Krankheiten

Country Status (11)

Country Link
EP (1) EP0404440B1 (de)
JP (1) JPH0753722B2 (de)
AT (1) ATE159941T1 (de)
CA (1) CA2019349A1 (de)
DE (1) DE69031669T2 (de)
DK (1) DK0404440T3 (de)
ES (1) ES2109229T3 (de)
FI (1) FI96951C (de)
GR (1) GR3025697T3 (de)
IE (1) IE902245A1 (de)
WO (1) WO1990015801A1 (de)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0480717B1 (de) * 1990-10-12 1998-04-15 Merck Frosst Canada Inc. Ungesättigte Hydroxyalkylchinolinsäuren als Leukotrien-Antagonisten
MX9300312A (es) * 1992-01-23 1993-07-31 Pfizer Antagonistas benzopiranicos y relacionado de ltb.
JP2813464B2 (ja) * 1992-01-23 1998-10-22 フアイザー・インコーポレイテツド ベンゾピラン及び関連ltb▲下4▼アンタゴニスト
CZ100095A3 (en) * 1992-10-21 1995-11-15 Pfizer Sulfonamide derivatives of hydroxy substituted alicyclic or heterocyclic compounds with condensed benzene nucleus and pharmaceutical preparations based thereon
WO1994019345A1 (en) * 1993-02-16 1994-09-01 Ube Industries, Ltd. Quinoline derivative
ES2084547B1 (es) * 1993-07-12 1997-01-16 Pfizer Antagonistas benzopiranicos y relacionados de leucotrieno b4.
US5539128A (en) * 1994-11-30 1996-07-23 Pfizer Inc. Processes and intermediates for preparing cis(+)3-[4,6-dihydroxy chroman-3-ylmethyl]-4-methoxyaniline
WO1997048694A1 (en) 1996-06-20 1997-12-24 Board Of Regents, The University Of Texas System Compounds and methods for providing pharmacologically active preparations and uses thereof
CA2413086C (en) * 2000-06-21 2011-06-28 Alexander Alanine Benzothiazole derivatives
US7087761B2 (en) 2003-01-07 2006-08-08 Hoffmann-La Roche Inc. Cyclization process for substituted benzothiazole derivatives
SI1753760T1 (sl) 2004-05-24 2008-04-30 Hoffmann La Roche (4-metoksi-7-morfolin-4-il-benzotiazol-2-il)-amid4- hidroksi-4-metil-piperidin-1-karboksilne kisline
CN101056857B (zh) 2004-11-05 2010-12-01 弗·哈夫曼-拉罗切有限公司 异烟酸衍生物的制备方法
RU2412943C2 (ru) 2005-03-23 2011-02-27 Ф. Хоффманн-Ля Рош Аг ПРОИЗВОДНЫЕ АЦЕТИЛЕНИЛ-ПИРАЗОЛО-ПИРИМИДИНА В КАЧЕСТВЕ АНТАГОНИСТОВ mGluR2
KR101121292B1 (ko) 2005-09-27 2012-04-13 에프. 호프만-라 로슈 아게 Mglur2 길항제로서 옥사다이아졸일 피라졸로-피리미딘

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4675405A (en) * 1984-09-21 1987-06-23 American Home Products Corporation Quinoline compounds as antiallergic and antithrombotic agents
US4845105A (en) * 1984-10-30 1989-07-04 Roussel Uclaf 4-OH-quinoline carboxylic acid amides having analgesic and anti-inflammatory activity
US4661596A (en) * 1985-02-21 1987-04-28 American Home Products Corporation Quinolinyl (or pyridinyl) methoxy substituted naphthalene compounds as antiallergic agents
US4738972A (en) * 1985-05-21 1988-04-19 Pfizer Inc. Hypoglycemic thiazolidinediones
GB8613592D0 (en) * 1986-06-04 1986-07-09 Roussel Lab Ltd Chemical compounds
MX13485A (es) * 1987-10-19 1993-05-01 Pfizer Procedimiento para obtener tetralinas, cromados y compuestos relacionados, sustituidos

Also Published As

Publication number Publication date
EP0404440A3 (de) 1992-01-08
EP0404440B1 (de) 1997-11-05
ATE159941T1 (de) 1997-11-15
DE69031669D1 (de) 1997-12-11
DK0404440T3 (da) 1997-12-22
EP0404440A2 (de) 1990-12-27
FI916065A0 (fi) 1991-12-20
ES2109229T3 (es) 1998-01-16
FI96951B (fi) 1996-06-14
IE902245A1 (en) 1991-01-16
JPH0753722B2 (ja) 1995-06-07
CA2019349A1 (en) 1990-12-22
FI96951C (fi) 1996-09-25
GR3025697T3 (en) 1998-03-31
IE902245L (en) 1990-12-22
WO1990015801A1 (en) 1990-12-27
JPH0338569A (ja) 1991-02-19

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee