ES2109229T3 - Sulfonamidas sustituidas y compuestos relacionados para el tratamiento del asma, la artritis y enfermedades relacionadas. - Google Patents

Sulfonamidas sustituidas y compuestos relacionados para el tratamiento del asma, la artritis y enfermedades relacionadas.

Info

Publication number
ES2109229T3
ES2109229T3 ES90306500T ES90306500T ES2109229T3 ES 2109229 T3 ES2109229 T3 ES 2109229T3 ES 90306500 T ES90306500 T ES 90306500T ES 90306500 T ES90306500 T ES 90306500T ES 2109229 T3 ES2109229 T3 ES 2109229T3
Authority
ES
Spain
Prior art keywords
asthma
arthritis
treatment
substituted sulfonamides
compounds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES90306500T
Other languages
English (en)
Inventor
James F Eggler
Hiroko Masamune
Anthony Marfat
Lawrence S Melvin
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Corp Belgium
Pfizer Corp SRL
Original Assignee
Pfizer Corp Belgium
Pfizer Corp SRL
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Corp Belgium, Pfizer Corp SRL filed Critical Pfizer Corp Belgium
Application granted granted Critical
Publication of ES2109229T3 publication Critical patent/ES2109229T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Cardiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Quinoline Compounds (AREA)
  • Cephalosporin Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

COMPUESTOS DE FORMULA (I) Y COMPOSICIONES FARMACEUTICAS QUE COMPRENDEN LOS MISMOS, DEONDE R1, R2, R3, W, X, Y Z SON COMO EN LA PATENTE SE DEFINE. LOS COMPUESTOS SON INHIBIDORES DE ENZINA S-LIPOXIGENOSA Y ANTAGONISTA DE LEUCOTRIENO B4, LEUCOTRINEO C4, LEUCOTRIENO D4 Y LEUCOTRIENO E4.
ES90306500T 1989-06-22 1990-06-14 Sulfonamidas sustituidas y compuestos relacionados para el tratamiento del asma, la artritis y enfermedades relacionadas. Expired - Lifetime ES2109229T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US1989/002748 WO1990015801A1 (en) 1989-06-22 1989-06-22 Substituted sulfonamides and related compounds in the treatment of asthma, arthritis and related diseases

Publications (1)

Publication Number Publication Date
ES2109229T3 true ES2109229T3 (es) 1998-01-16

Family

ID=22215089

Family Applications (1)

Application Number Title Priority Date Filing Date
ES90306500T Expired - Lifetime ES2109229T3 (es) 1989-06-22 1990-06-14 Sulfonamidas sustituidas y compuestos relacionados para el tratamiento del asma, la artritis y enfermedades relacionadas.

Country Status (11)

Country Link
EP (1) EP0404440B1 (es)
JP (1) JPH0753722B2 (es)
AT (1) ATE159941T1 (es)
CA (1) CA2019349A1 (es)
DE (1) DE69031669T2 (es)
DK (1) DK0404440T3 (es)
ES (1) ES2109229T3 (es)
FI (1) FI96951C (es)
GR (1) GR3025697T3 (es)
IE (1) IE902245A1 (es)
WO (1) WO1990015801A1 (es)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU222344B1 (hu) * 1990-10-12 2003-06-28 Merck Frosst Canada & Co. Eljárás telítetlen hidroxi-alkil-kinolinsavak, és ezeket tartalmazó gyógyszerkészítmények előállítására
MX9300312A (es) * 1992-01-23 1993-07-31 Pfizer Antagonistas benzopiranicos y relacionado de ltb.
ES2098547T3 (es) * 1992-01-23 1997-05-01 Pfizer Benzopirano y otros antagonistas de ltb4 relacionados.
CZ100095A3 (en) * 1992-10-21 1995-11-15 Pfizer Sulfonamide derivatives of hydroxy substituted alicyclic or heterocyclic compounds with condensed benzene nucleus and pharmaceutical preparations based thereon
AU674569B2 (en) * 1993-02-16 1997-01-02 Ube Industries, Ltd. Quinoline derivative
ES2084547B1 (es) * 1993-07-12 1997-01-16 Pfizer Antagonistas benzopiranicos y relacionados de leucotrieno b4.
US5539128A (en) * 1994-11-30 1996-07-23 Pfizer Inc. Processes and intermediates for preparing cis(+)3-[4,6-dihydroxy chroman-3-ylmethyl]-4-methoxyaniline
BR9711805A (pt) 1996-06-20 2002-01-15 Regents The Univesity Of Texas Compostos e métodos para providenciar preparações farmacologicamente ativas e uso dos mesmos
CZ2003182A3 (cs) 2000-06-21 2003-06-18 F. Hoffmann-La Roche Ag Deriváty benzothiazolu
US7087761B2 (en) 2003-01-07 2006-08-08 Hoffmann-La Roche Inc. Cyclization process for substituted benzothiazole derivatives
DE602005004142T2 (de) 2004-05-24 2009-01-02 F. Hoffmann-La Roche Ag 4-hydroxy-4-methylpiperidin-1-carbonsäure-(4-methoxy-7-morpholin-4-ylbenzothiazol-2-yl)-amid
ATE400557T1 (de) 2004-11-05 2008-07-15 Hoffmann La Roche Verfahren zur herstellung von isonikotinsäurederivaten
ATE460417T1 (de) 2005-03-23 2010-03-15 Hoffmann La Roche Acetylenylpyrazolopyrimidinderivate als mglur2- antagonsten
ES2340321T3 (es) 2005-09-27 2010-06-01 F.Hoffmann-La Roche Ag Oxadiazolilpirazolo-pirimidinas, como antagonistas de mglur2.

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4675405A (en) * 1984-09-21 1987-06-23 American Home Products Corporation Quinoline compounds as antiallergic and antithrombotic agents
US4845105A (en) * 1984-10-30 1989-07-04 Roussel Uclaf 4-OH-quinoline carboxylic acid amides having analgesic and anti-inflammatory activity
US4661596A (en) * 1985-02-21 1987-04-28 American Home Products Corporation Quinolinyl (or pyridinyl) methoxy substituted naphthalene compounds as antiallergic agents
US4738972A (en) * 1985-05-21 1988-04-19 Pfizer Inc. Hypoglycemic thiazolidinediones
GB8613592D0 (en) * 1986-06-04 1986-07-09 Roussel Lab Ltd Chemical compounds
MX13485A (es) * 1987-10-19 1993-05-01 Pfizer Procedimiento para obtener tetralinas, cromados y compuestos relacionados, sustituidos

Also Published As

Publication number Publication date
FI916065A0 (fi) 1991-12-20
DE69031669D1 (de) 1997-12-11
JPH0753722B2 (ja) 1995-06-07
FI96951C (fi) 1996-09-25
WO1990015801A1 (en) 1990-12-27
CA2019349A1 (en) 1990-12-22
GR3025697T3 (en) 1998-03-31
IE902245L (en) 1990-12-22
DE69031669T2 (de) 1998-03-05
FI96951B (fi) 1996-06-14
ATE159941T1 (de) 1997-11-15
EP0404440A2 (en) 1990-12-27
IE902245A1 (en) 1991-01-16
JPH0338569A (ja) 1991-02-19
DK0404440T3 (da) 1997-12-22
EP0404440A3 (en) 1992-01-08
EP0404440B1 (en) 1997-11-05

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