DE69029587T2 - Verfahren zur herstellung von 3-trifluormethylbenzylchlorid - Google Patents
Verfahren zur herstellung von 3-trifluormethylbenzylchloridInfo
- Publication number
- DE69029587T2 DE69029587T2 DE69029587T DE69029587T DE69029587T2 DE 69029587 T2 DE69029587 T2 DE 69029587T2 DE 69029587 T DE69029587 T DE 69029587T DE 69029587 T DE69029587 T DE 69029587T DE 69029587 T2 DE69029587 T2 DE 69029587T2
- Authority
- DE
- Germany
- Prior art keywords
- trifluormethylbenzyl
- chloride
- producing
- trifluormethylbenzyl chloride
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
- C07C255/01—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms
- C07C255/32—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms having cyano groups bound to acyclic carbon atoms of a carbon skeleton containing at least one six-membered aromatic ring
- C07C255/35—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms having cyano groups bound to acyclic carbon atoms of a carbon skeleton containing at least one six-membered aromatic ring the carbon skeleton being further substituted by halogen atoms, or by nitro or nitroso groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C17/00—Preparation of halogenated hydrocarbons
- C07C17/093—Preparation of halogenated hydrocarbons by replacement by halogens
- C07C17/10—Preparation of halogenated hydrocarbons by replacement by halogens of hydrogen atoms
- C07C17/14—Preparation of halogenated hydrocarbons by replacement by halogens of hydrogen atoms in the side-chain of aromatic compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C17/00—Preparation of halogenated hydrocarbons
- C07C17/093—Preparation of halogenated hydrocarbons by replacement by halogens
- C07C17/20—Preparation of halogenated hydrocarbons by replacement by halogens of halogen atoms by other halogen atoms
- C07C17/202—Preparation of halogenated hydrocarbons by replacement by halogens of halogen atoms by other halogen atoms two or more compounds being involved in the reaction
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C17/00—Preparation of halogenated hydrocarbons
- C07C17/093—Preparation of halogenated hydrocarbons by replacement by halogens
- C07C17/20—Preparation of halogenated hydrocarbons by replacement by halogens of halogen atoms by other halogen atoms
- C07C17/202—Preparation of halogenated hydrocarbons by replacement by halogens of halogen atoms by other halogen atoms two or more compounds being involved in the reaction
- C07C17/204—Preparation of halogenated hydrocarbons by replacement by halogens of halogen atoms by other halogen atoms two or more compounds being involved in the reaction the other compound being a halogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C17/00—Preparation of halogenated hydrocarbons
- C07C17/093—Preparation of halogenated hydrocarbons by replacement by halogens
- C07C17/20—Preparation of halogenated hydrocarbons by replacement by halogens of halogen atoms by other halogen atoms
- C07C17/202—Preparation of halogenated hydrocarbons by replacement by halogens of halogen atoms by other halogen atoms two or more compounds being involved in the reaction
- C07C17/206—Preparation of halogenated hydrocarbons by replacement by halogens of halogen atoms by other halogen atoms two or more compounds being involved in the reaction the other compound being HX
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PCT/US1990/006082 WO1992007820A1 (en) | 1990-10-26 | 1990-10-26 | Process for preparing 3-trifluoromethyl benzyl chloride |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69029587D1 DE69029587D1 (de) | 1997-02-13 |
DE69029587T2 true DE69029587T2 (de) | 1997-04-24 |
Family
ID=22221109
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69029587T Expired - Lifetime DE69029587T2 (de) | 1990-10-26 | 1990-10-26 | Verfahren zur herstellung von 3-trifluormethylbenzylchlorid |
Country Status (7)
Country | Link |
---|---|
US (1) | US4966988A (de) |
EP (1) | EP0563033B1 (de) |
AU (1) | AU640964B2 (de) |
BR (1) | BR9008041A (de) |
CA (1) | CA2089271C (de) |
DE (1) | DE69029587T2 (de) |
WO (1) | WO1992007820A1 (de) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP3638790B2 (ja) * | 1998-04-27 | 2005-04-13 | セントラル硝子株式会社 | ビストリフルオロメチルベンゼンの製造方法 |
KR20070116286A (ko) * | 2005-05-16 | 2007-12-07 | 테바 파마슈티컬 인더스트리즈 리미티드 | 시나칼셋 염산염의 제조 방법 |
KR20080007376A (ko) * | 2005-05-23 | 2008-01-18 | 테바 파마슈티컬 인더스트리즈 리미티드 | 무정형 시나칼셋 염산염 및 이의 제조 |
KR20070083471A (ko) | 2005-05-23 | 2007-08-24 | 테바 파마슈티컬 인더스트리즈 리미티드 | 시나칼셋 염산염 결정형 i의 제조 방법 |
KR20080055990A (ko) * | 2005-11-22 | 2008-06-19 | 테바 파마슈티컬 인더스트리즈 리미티드 | 시나칼셋 HCl의 결정형 및 이의 제조 방법 |
JP5027214B2 (ja) * | 2006-04-27 | 2012-09-19 | テバ ファーマシューティカル インダストリーズ リミティド | シナカルセット塩基の調製法 |
EP1928817A1 (de) * | 2006-04-27 | 2008-06-11 | Teva Pharmaceutical Industries Ltd | Verfahren zur herstellung von cinacalcetbase |
WO2008063645A1 (en) * | 2006-11-20 | 2008-05-29 | Teva Pharmaceutical Industries Ltd. | Process for preparing cinacalcet |
WO2009025792A2 (en) * | 2007-08-16 | 2009-02-26 | Teva Pharmaceutical Industries Ltd. | Crystalline forms cinacalcet fumarate and cinacalcet succinate and processes for preparation thereof |
WO2010103531A2 (en) | 2009-03-09 | 2010-09-16 | Megafine Pharma (P) Ltd. | A new method for the preparation of cinacalcet and new intermediates thereof |
US8722732B2 (en) | 2009-09-29 | 2014-05-13 | Nektar Therapeutics | Oligomer-calcimimetic conjugates and related compounds |
AU2010315805B2 (en) | 2009-09-29 | 2015-09-17 | Nektar Therapeutics | Oligomer-calcimimetic conjugates and related compounds |
CN104447402B (zh) * | 2014-11-27 | 2016-05-11 | 上海赫腾精细化工有限公司 | 间三氟甲基苯乙腈的制备方法 |
Family Cites Families (25)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA526939A (en) * | 1956-06-26 | Dengel Ferdinand | Method of producing nitriles | |
US2005712A (en) * | 1932-08-31 | 1935-06-18 | Kinetic Chemicals Inc | Organic fluorine compounds and process for the production thereof |
DE668033C (de) * | 1935-10-26 | 1938-11-25 | I G Farbenindustrie Akt Ges | Verfahren zur Herstellung von o-Trifluormethyldifluorchlormethylbenzolen bzw. o-Hexafluordimethylbenzolen |
US2956084A (en) * | 1959-03-27 | 1960-10-11 | Exxon Research Engineering Co | Process for chlorinating hydrocarbons using chlorine adsorbed on zeolite |
US3136822A (en) * | 1961-05-02 | 1964-06-09 | Olin Mathieson | Process for the preparation of benzotrifluoride |
DE1443825A1 (de) * | 1962-02-24 | 1969-12-18 | Hoechst Ag | Verfahren zur Herstellung von gegebenenfalls halogensubstituierten Mononitrobenzotrichloriden |
US3363013A (en) * | 1965-05-20 | 1968-01-09 | Velsicol Chemical Corp | Chlorination process |
US3350467A (en) * | 1966-04-20 | 1967-10-31 | Diamond Alkali Co | Method for side-chain chlorination of xylene |
CA1029746A (en) * | 1973-11-10 | 1978-04-18 | Hoechst Aktiengesellschaft | Process for preparing derivatives of benzene fluorinated in the lateral chains |
DE2549095C3 (de) * | 1975-11-03 | 1978-04-20 | Bayer Ag, 5090 Leverkusen | Verfahren zur Herstellung von in den Seitenketten fluorierten und chlorierten Xylolen |
US4163753A (en) * | 1977-02-14 | 1979-08-07 | Diaz Chemical Corporation | Process for the simultaneous preparation of aromatic acid chlorides and aliphatic acid chlorides |
DE2708190C2 (de) * | 1977-02-25 | 1984-09-27 | Bayer Ag, 5090 Leverkusen | Verfahren zur Herstellung von m-Brom-benzotrifluoriden |
US4144265A (en) * | 1978-07-17 | 1979-03-13 | The Dow Chemical Company | Process for the manufacture of m-trifluoromethyl benzyl nitrile |
US4252624A (en) * | 1979-04-24 | 1981-02-24 | Eli Lilly And Company | Bromination of m-ethyldiphenyl ether |
JPS5610129A (en) * | 1979-07-05 | 1981-02-02 | Mitsubishi Gas Chem Co Inc | Preparation of aromatic dialdehyde |
JPS5620561A (en) * | 1979-07-30 | 1981-02-26 | Shell Int Research | Manufacture of benzylcyanides |
DE3106170C2 (de) * | 1980-02-22 | 1984-06-20 | Kureha Kagaku Kogyo K.K., Tokio/Tokyo | 3,3,3-trifluorpropylierte Benzolderivate |
US4360478A (en) * | 1980-05-12 | 1982-11-23 | Shell Oil Company | Preparation of α-cyanobenzyl esters |
US4367348A (en) * | 1980-10-10 | 1983-01-04 | Occidental Chemical Corporation | Novel trifluoromethyl benzal chlorides and process for the preparation thereof |
US4467125A (en) * | 1983-06-10 | 1984-08-21 | Monsanto Company | Nitro-methyl or ethyl substituted benzotrifluoride |
EP0150169B1 (de) * | 1984-01-23 | 1987-11-11 | Monsanto Company | Verfahren zur Herstellung von substituierten Trichlormethylbenzolen |
US4593144A (en) * | 1984-01-23 | 1986-06-03 | Monsanto Company | Process for preparing substituted benzotrichloride compounds |
US4568376A (en) * | 1984-05-09 | 1986-02-04 | Chevron Research Company | Herbicidal 5-amino-3-oxo-4-(substituted-phenyl)-2,3-dihydrofuran and derivatives thereof |
ATE32061T1 (de) * | 1984-06-15 | 1988-02-15 | Heumann Ludwig & Co Gmbh | Verfahren zur herstellung basisch substituierter phenylacetonitrile. |
DE3717434C1 (de) * | 1987-05-23 | 1988-09-15 | Degussa | Verfahren zur Herstellung von m-Trifluormethylphenylacetonitril |
-
1989
- 1989-02-17 US US07/312,140 patent/US4966988A/en not_active Expired - Lifetime
-
1990
- 1990-10-26 CA CA002089271A patent/CA2089271C/en not_active Expired - Lifetime
- 1990-10-26 WO PCT/US1990/006082 patent/WO1992007820A1/en active IP Right Grant
- 1990-10-26 DE DE69029587T patent/DE69029587T2/de not_active Expired - Lifetime
- 1990-10-26 BR BR909008041A patent/BR9008041A/pt not_active IP Right Cessation
- 1990-10-26 EP EP90915845A patent/EP0563033B1/de not_active Expired - Lifetime
- 1990-10-26 AU AU66075/90A patent/AU640964B2/en not_active Expired
Also Published As
Publication number | Publication date |
---|---|
AU640964B2 (en) | 1993-09-09 |
WO1992007820A1 (en) | 1992-05-14 |
DE69029587D1 (de) | 1997-02-13 |
CA2089271A1 (en) | 1992-04-27 |
EP0563033B1 (de) | 1997-01-02 |
EP0563033A1 (de) | 1993-10-06 |
BR9008041A (pt) | 1993-08-24 |
AU6607590A (en) | 1992-05-26 |
EP0563033A4 (en) | 1994-05-18 |
US4966988A (en) | 1990-10-30 |
CA2089271C (en) | 2002-12-17 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition |