DE69029587D1 - Verfahren zur herstellung von 3-trifluormethylbenzylchlorid - Google Patents

Verfahren zur herstellung von 3-trifluormethylbenzylchlorid

Info

Publication number
DE69029587D1
DE69029587D1 DE69029587T DE69029587T DE69029587D1 DE 69029587 D1 DE69029587 D1 DE 69029587D1 DE 69029587 T DE69029587 T DE 69029587T DE 69029587 T DE69029587 T DE 69029587T DE 69029587 D1 DE69029587 D1 DE 69029587D1
Authority
DE
Germany
Prior art keywords
trifluormethylbenzyl
chloride
producing
trifluormethylbenzyl chloride
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69029587T
Other languages
English (en)
Other versions
DE69029587T2 (de
Inventor
William Schinski
Peter Denisevich
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Chevron USA Inc
Original Assignee
Chevron USA Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chevron USA Inc filed Critical Chevron USA Inc
Application granted granted Critical
Publication of DE69029587D1 publication Critical patent/DE69029587D1/de
Publication of DE69029587T2 publication Critical patent/DE69029587T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C07C255/01—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms
    • C07C255/32—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms having cyano groups bound to acyclic carbon atoms of a carbon skeleton containing at least one six-membered aromatic ring
    • C07C255/35—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms having cyano groups bound to acyclic carbon atoms of a carbon skeleton containing at least one six-membered aromatic ring the carbon skeleton being further substituted by halogen atoms, or by nitro or nitroso groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C17/00—Preparation of halogenated hydrocarbons
    • C07C17/093—Preparation of halogenated hydrocarbons by replacement by halogens
    • C07C17/10—Preparation of halogenated hydrocarbons by replacement by halogens of hydrogen atoms
    • C07C17/14—Preparation of halogenated hydrocarbons by replacement by halogens of hydrogen atoms in the side-chain of aromatic compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C17/00—Preparation of halogenated hydrocarbons
    • C07C17/093—Preparation of halogenated hydrocarbons by replacement by halogens
    • C07C17/20—Preparation of halogenated hydrocarbons by replacement by halogens of halogen atoms by other halogen atoms
    • C07C17/202—Preparation of halogenated hydrocarbons by replacement by halogens of halogen atoms by other halogen atoms two or more compounds being involved in the reaction
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C17/00—Preparation of halogenated hydrocarbons
    • C07C17/093—Preparation of halogenated hydrocarbons by replacement by halogens
    • C07C17/20—Preparation of halogenated hydrocarbons by replacement by halogens of halogen atoms by other halogen atoms
    • C07C17/202—Preparation of halogenated hydrocarbons by replacement by halogens of halogen atoms by other halogen atoms two or more compounds being involved in the reaction
    • C07C17/204—Preparation of halogenated hydrocarbons by replacement by halogens of halogen atoms by other halogen atoms two or more compounds being involved in the reaction the other compound being a halogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C17/00—Preparation of halogenated hydrocarbons
    • C07C17/093—Preparation of halogenated hydrocarbons by replacement by halogens
    • C07C17/20—Preparation of halogenated hydrocarbons by replacement by halogens of halogen atoms by other halogen atoms
    • C07C17/202—Preparation of halogenated hydrocarbons by replacement by halogens of halogen atoms by other halogen atoms two or more compounds being involved in the reaction
    • C07C17/206—Preparation of halogenated hydrocarbons by replacement by halogens of halogen atoms by other halogen atoms two or more compounds being involved in the reaction the other compound being HX

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
DE69029587T 1990-10-26 1990-10-26 Verfahren zur herstellung von 3-trifluormethylbenzylchlorid Expired - Lifetime DE69029587T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US1990/006082 WO1992007820A1 (en) 1990-10-26 1990-10-26 Process for preparing 3-trifluoromethyl benzyl chloride

Publications (2)

Publication Number Publication Date
DE69029587D1 true DE69029587D1 (de) 1997-02-13
DE69029587T2 DE69029587T2 (de) 1997-04-24

Family

ID=22221109

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69029587T Expired - Lifetime DE69029587T2 (de) 1990-10-26 1990-10-26 Verfahren zur herstellung von 3-trifluormethylbenzylchlorid

Country Status (7)

Country Link
US (1) US4966988A (de)
EP (1) EP0563033B1 (de)
AU (1) AU640964B2 (de)
BR (1) BR9008041A (de)
CA (1) CA2089271C (de)
DE (1) DE69029587T2 (de)
WO (1) WO1992007820A1 (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3638790B2 (ja) * 1998-04-27 2005-04-13 セントラル硝子株式会社 ビストリフルオロメチルベンゼンの製造方法
US7250533B2 (en) * 2005-05-16 2007-07-31 Teva Pharmaceutical Industries Ltd Process for preparing Cinacalcet hydrochloride
EP1975150A1 (de) * 2005-05-23 2008-10-01 Teva Pharmaceutical Industries Ltd. Cinacalcetsalze
EP1883625A2 (de) * 2005-05-23 2008-02-06 Teva Pharmaceutical Industries Ltd Amorphes cinacalcet hydrochlorid und seine herstellung
WO2007062147A1 (en) * 2005-11-22 2007-05-31 Teva Pharmaceutical Industries Ltd. Crystal forms of cinacalcet hci and processes for their preparation
JP5027214B2 (ja) * 2006-04-27 2012-09-19 テバ ファーマシューティカル インダストリーズ リミティド シナカルセット塩基の調製法
TW200811082A (en) * 2006-04-27 2008-03-01 Teva Pharma Process for the preparation of cinacalcet base
US20080146845A1 (en) * 2006-11-20 2008-06-19 Boaz Gome Process for preparing Cinacalcet
US20090093652A1 (en) * 2007-08-16 2009-04-09 Michal Rafilovich Crystalline forms cinacalcet fumarate and cinacalcet succinate and processes for preparation thereof
EP2406211B1 (de) 2009-03-09 2018-06-27 Megafine Pharma (P) Ltd. Neues verfahren zur herstellung von cinacalcet und neues zwischenprodukt davon
US8722732B2 (en) 2009-09-29 2014-05-13 Nektar Therapeutics Oligomer-calcimimetic conjugates and related compounds
AU2010315805B2 (en) 2009-09-29 2015-09-17 Nektar Therapeutics Oligomer-calcimimetic conjugates and related compounds
CN104447402B (zh) * 2014-11-27 2016-05-11 上海赫腾精细化工有限公司 间三氟甲基苯乙腈的制备方法

Family Cites Families (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA526939A (en) * 1956-06-26 Dengel Ferdinand Method of producing nitriles
US2005712A (en) * 1932-08-31 1935-06-18 Kinetic Chemicals Inc Organic fluorine compounds and process for the production thereof
DE668033C (de) * 1935-10-26 1938-11-25 I G Farbenindustrie Akt Ges Verfahren zur Herstellung von o-Trifluormethyldifluorchlormethylbenzolen bzw. o-Hexafluordimethylbenzolen
US2956084A (en) * 1959-03-27 1960-10-11 Exxon Research Engineering Co Process for chlorinating hydrocarbons using chlorine adsorbed on zeolite
US3136822A (en) * 1961-05-02 1964-06-09 Olin Mathieson Process for the preparation of benzotrifluoride
DE1443825A1 (de) * 1962-02-24 1969-12-18 Hoechst Ag Verfahren zur Herstellung von gegebenenfalls halogensubstituierten Mononitrobenzotrichloriden
US3363013A (en) * 1965-05-20 1968-01-09 Velsicol Chemical Corp Chlorination process
US3350467A (en) * 1966-04-20 1967-10-31 Diamond Alkali Co Method for side-chain chlorination of xylene
CA1029746A (en) * 1973-11-10 1978-04-18 Hoechst Aktiengesellschaft Process for preparing derivatives of benzene fluorinated in the lateral chains
DE2549095C3 (de) * 1975-11-03 1978-04-20 Bayer Ag, 5090 Leverkusen Verfahren zur Herstellung von in den Seitenketten fluorierten und chlorierten Xylolen
US4163753A (en) * 1977-02-14 1979-08-07 Diaz Chemical Corporation Process for the simultaneous preparation of aromatic acid chlorides and aliphatic acid chlorides
DE2708190C2 (de) * 1977-02-25 1984-09-27 Bayer Ag, 5090 Leverkusen Verfahren zur Herstellung von m-Brom-benzotrifluoriden
US4144265A (en) * 1978-07-17 1979-03-13 The Dow Chemical Company Process for the manufacture of m-trifluoromethyl benzyl nitrile
US4252624A (en) * 1979-04-24 1981-02-24 Eli Lilly And Company Bromination of m-ethyldiphenyl ether
JPS5610129A (en) * 1979-07-05 1981-02-02 Mitsubishi Gas Chem Co Inc Preparation of aromatic dialdehyde
JPS5620561A (en) * 1979-07-30 1981-02-26 Shell Int Research Manufacture of benzylcyanides
DE3106170C2 (de) * 1980-02-22 1984-06-20 Kureha Kagaku Kogyo K.K., Tokio/Tokyo 3,3,3-trifluorpropylierte Benzolderivate
US4360478A (en) * 1980-05-12 1982-11-23 Shell Oil Company Preparation of α-cyanobenzyl esters
US4367348A (en) * 1980-10-10 1983-01-04 Occidental Chemical Corporation Novel trifluoromethyl benzal chlorides and process for the preparation thereof
US4467125A (en) * 1983-06-10 1984-08-21 Monsanto Company Nitro-methyl or ethyl substituted benzotrifluoride
US4593144A (en) * 1984-01-23 1986-06-03 Monsanto Company Process for preparing substituted benzotrichloride compounds
DE3560943D1 (en) * 1984-01-23 1987-12-17 Monsanto Co A process for preparing substituted benzotrichloride compounds
US4568376A (en) * 1984-05-09 1986-02-04 Chevron Research Company Herbicidal 5-amino-3-oxo-4-(substituted-phenyl)-2,3-dihydrofuran and derivatives thereof
ATE32061T1 (de) * 1984-06-15 1988-02-15 Heumann Ludwig & Co Gmbh Verfahren zur herstellung basisch substituierter phenylacetonitrile.
DE3717434C1 (de) * 1987-05-23 1988-09-15 Degussa Verfahren zur Herstellung von m-Trifluormethylphenylacetonitril

Also Published As

Publication number Publication date
DE69029587T2 (de) 1997-04-24
WO1992007820A1 (en) 1992-05-14
EP0563033A1 (de) 1993-10-06
EP0563033B1 (de) 1997-01-02
CA2089271A1 (en) 1992-04-27
EP0563033A4 (en) 1994-05-18
CA2089271C (en) 2002-12-17
AU640964B2 (en) 1993-09-09
AU6607590A (en) 1992-05-26
BR9008041A (pt) 1993-08-24
US4966988A (en) 1990-10-30

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