DE69021953T2 - Enzymimmuntest für Antigene und dafür verwendbare feste Phase. - Google Patents

Enzymimmuntest für Antigene und dafür verwendbare feste Phase.

Info

Publication number
DE69021953T2
DE69021953T2 DE69021953T DE69021953T DE69021953T2 DE 69021953 T2 DE69021953 T2 DE 69021953T2 DE 69021953 T DE69021953 T DE 69021953T DE 69021953 T DE69021953 T DE 69021953T DE 69021953 T2 DE69021953 T2 DE 69021953T2
Authority
DE
Germany
Prior art keywords
antigens
solid phase
enzyme immunoassay
immunoassay
enzyme
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69021953T
Other languages
English (en)
Other versions
DE69021953D1 (de
Inventor
Yoji Marui
Chozo Hayashi
Shigeki Ito
Mieko Fujio
Hiroki Tanaka
Toshihide Nagasaki
Yasuji Soda
Hitoshi Kaneta
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nippon Shoji Co Ltd
Original Assignee
Nippon Shoji Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26411503&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE69021953(T2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Nippon Shoji Co Ltd filed Critical Nippon Shoji Co Ltd
Application granted granted Critical
Publication of DE69021953D1 publication Critical patent/DE69021953D1/de
Publication of DE69021953T2 publication Critical patent/DE69021953T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57473—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving carcinoembryonic antigen, i.e. CEA
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54306—Solid-phase reaction mechanisms
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54353—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals with ligand attached to the carrier via a chemical coupling agent
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57476—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving oncofetal proteins
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/581—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with enzyme label (including co-enzymes, co-factors, enzyme inhibitors or substrates)
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6878—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids in eptitope analysis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Pathology (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Oncology (AREA)
  • Hospice & Palliative Care (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
DE69021953T 1989-06-29 1990-06-29 Enzymimmuntest für Antigene und dafür verwendbare feste Phase. Expired - Fee Related DE69021953T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP16769789 1989-06-29
JP2070341A JP2619549B2 (ja) 1989-06-29 1990-03-20 抗原の定量法およびそれに用いる固相

Publications (2)

Publication Number Publication Date
DE69021953D1 DE69021953D1 (de) 1995-10-05
DE69021953T2 true DE69021953T2 (de) 1996-04-04

Family

ID=26411503

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69021953T Expired - Fee Related DE69021953T2 (de) 1989-06-29 1990-06-29 Enzymimmuntest für Antigene und dafür verwendbare feste Phase.

Country Status (8)

Country Link
US (1) US5378608A (de)
EP (2) EP0405578B1 (de)
JP (1) JP2619549B2 (de)
DE (1) DE69021953T2 (de)
DK (1) DK0405578T3 (de)
ES (1) ES2078923T3 (de)
FI (1) FI101022B (de)
NO (1) NO178047C (de)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6274325B1 (en) * 1990-06-25 2001-08-14 Boehringer Mannheim Gmbh Method for carrying out a homogeneous-immunoassay based on agglutination
JP2968039B2 (ja) * 1990-11-29 1999-10-25 株式会社京都第一科学 化学発光免疫測定法
DE4140142A1 (de) * 1991-12-05 1993-06-09 Boehringer Mannheim Gmbh, 6800 Mannheim, De Multivalentes dextranreagenz zum einsatz in praezipitationstests
ES2051247B1 (es) * 1992-11-27 1994-12-16 Univ Cordoba Procedimiento para la deteccion y medida de los niveles de hormona luteotropica porcina.
US5747352A (en) * 1994-05-23 1998-05-05 Beckman Instruments, Inc. Reagents and methods for the rapid and quantitative assay of pharmacological agents
DE19530078A1 (de) * 1995-08-16 1997-02-20 Bayer Ag Optischer Festphasenbiosensor auf Basis von Streptavidin und Biotin
DE19534988A1 (de) * 1995-09-21 1997-03-27 Forssmann Wolf Georg Verfahren zur Herstellung und Anwendung synthetischer, biotinylierter Peptide
US5958704A (en) * 1997-03-12 1999-09-28 Ddx, Inc. Sensing system for specific substance and molecule detection
US6303325B1 (en) 1998-05-29 2001-10-16 Dade Behring Inc. Method for detecting analytes
WO2000028326A1 (fr) * 1998-11-06 2000-05-18 Iatron Laboratories, Inc. Nouveaux complexes contenant de l'avidine reticulee, procede analytique dans lequel on utilise de l'avidine reticulee, reactifs et kits d'analyse
US7105311B2 (en) * 2001-05-03 2006-09-12 Immunetics, Inc. Systems and methods for detection of analytes in biological fluids
US20040209294A1 (en) * 2002-09-02 2004-10-21 National Food Research Institute Method to produce a receptor chip using biotinylated protein
CA2515213A1 (en) * 2003-02-11 2004-08-26 University Of Washington Stimuli-responsive polymer conjugates and related methods
US20040248223A1 (en) * 2003-06-05 2004-12-09 Idexx Laboratories, Inc. Reduction of interfering peroxidase activity in peroxidase based detection methods
CN101529251B (zh) * 2006-11-01 2014-04-02 贝克曼考尔特公司 用于亲合分析的结合性表面
US7981688B2 (en) 2007-03-08 2011-07-19 University Of Washington Stimuli-responsive magnetic nanoparticles and related methods
US8426214B2 (en) * 2009-06-12 2013-04-23 University Of Washington System and method for magnetically concentrating and detecting biomarkers
US20110117668A1 (en) * 2009-11-09 2011-05-19 University Of Washington Through Its Center For Commercialization Self-powered smart diagnostic devices
US9080933B2 (en) 2009-11-09 2015-07-14 University Of Washington Through Its Center For Commercialization Stimuli-responsive polymer diagnostic assay comprising magnetic nanoparticles and capture conjugates
US9005910B2 (en) 2010-04-14 2015-04-14 Eiken Kagaku Kabushiki Kaisha Complex of labeled probes and water-soluble carrier
US9588110B2 (en) * 2011-07-28 2017-03-07 Cell Signaling Technology, Inc. Multi component antibody based detection technology

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE430062B (sv) * 1977-03-04 1983-10-17 Pharmacia Fine Chemicals Ab Kopplings- eller tioleringsreagens
JPS5510590A (en) * 1978-05-04 1980-01-25 Wellcome Found Enzyme immunity quantity analysis
US4282287A (en) * 1980-01-24 1981-08-04 Giese Roger W Biochemical avidin-biotin multiple-layer system
SE8003732L (sv) * 1980-05-19 1981-11-20 Pharmacia Diagnostics Ab Sett vid bestemningsmetoder involverande biospecifika affinitetsreaktioner
DE3263249D1 (en) * 1981-08-21 1985-05-30 Hoffmann La Roche Method for the determination of carcinoembryonic antigen (cea) and suitable antibody solution for the determination
US4434150A (en) * 1981-10-19 1984-02-28 Ortho Diagnostic Systems, Inc. Immunological reagents employing polymeric backbone possessing reactive functional groups
US4429008B1 (en) * 1981-12-10 1995-05-16 Univ California Thiol reactive liposomes
GB8307156D0 (en) * 1983-03-15 1983-04-20 Celltech Ltd Heterogeneous binding assays
US4496654A (en) * 1983-04-08 1985-01-29 Quidel Detection of HCG with solid phase support having avidin coating
US4935339A (en) * 1985-05-07 1990-06-19 Nichols Institute Diagnostics Delayed solid phase immunologic assay
EP0256117A1 (de) * 1986-02-06 1988-02-24 Microbiological Associates, Inc. Latexagglutinierung mittels avidin-biotin-system
US4778751A (en) * 1986-05-12 1988-10-18 Diagnostic Products Corporation Method for measuring antigens or antibodies in biological fluids using ligand labeled antigens or ligand labeled antibodies
US4798795A (en) * 1987-02-17 1989-01-17 Hoechst Celanese Corporation Biotinylating agents
JPH07107537B2 (ja) * 1987-08-03 1995-11-15 イーストマン コダック カンパニー アビジン−及びビオチン−固定試薬，分析要素並びにその使用法
US4916075A (en) * 1987-08-19 1990-04-10 Ohmicron Corporation Differential homogeneous immunosensor device
JPS6488367A (en) * 1987-09-30 1989-04-03 Japan Chem Res Immobilized antibody
WO1990004786A1 (en) * 1988-10-17 1990-05-03 Molecular Devices Corporation Hapten derivatized capture membrane and diagnostic assays using such membrane

Also Published As

Publication number Publication date
FI101022B (fi) 1998-03-31
FI903228A0 (fi) 1990-06-27
JP2619549B2 (ja) 1997-06-11
US5378608A (en) 1995-01-03
DK0405578T3 (da) 1995-09-18
EP0405578B1 (de) 1995-08-30
ES2078923T3 (es) 1996-01-01
JPH03128460A (ja) 1991-05-31
EP0405578A2 (de) 1991-01-02
EP0405578A3 (en) 1991-05-29
NO178047B (no) 1995-10-02
NO902899L (no) 1991-01-02
NO902899D0 (no) 1990-06-28
NO178047C (no) 1996-01-10
EP0620438A1 (de) 1994-10-19
DE69021953D1 (de) 1995-10-05

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Legal Events

Date Code Title Description
8363 Opposition against the patent
8339 Ceased/non-payment of the annual fee