DE69019920T2 - Benzocycloalkylaminopyridinamine und verwandte Verbindungen, Verfahren zu ihrer Herstellung, Zwischenverbindungen und ihre Verwendung als Arzneimittel. - Google Patents
Benzocycloalkylaminopyridinamine und verwandte Verbindungen, Verfahren zu ihrer Herstellung, Zwischenverbindungen und ihre Verwendung als Arzneimittel.Info
- Publication number
- DE69019920T2 DE69019920T2 DE69019920T DE69019920T DE69019920T2 DE 69019920 T2 DE69019920 T2 DE 69019920T2 DE 69019920 T DE69019920 T DE 69019920T DE 69019920 T DE69019920 T DE 69019920T DE 69019920 T2 DE69019920 T2 DE 69019920T2
- Authority
- DE
- Germany
- Prior art keywords
- intermediates
- preparation
- benzocycloalkylaminopyridinamines
- medicines
- processes
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Rheumatology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Dermatology (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyridine Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Display Devices Of Pinball Game Machines (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US07/425,712 US4992448A (en) | 1989-10-24 | 1989-10-24 | Benzocycloalkylaminopyridinamines and related compounds as topical antiinflammatory agents for the treatment of skin disorders |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69019920D1 DE69019920D1 (de) | 1995-07-13 |
DE69019920T2 true DE69019920T2 (de) | 1995-11-16 |
Family
ID=23687722
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69019920T Expired - Fee Related DE69019920T2 (de) | 1989-10-24 | 1990-10-22 | Benzocycloalkylaminopyridinamine und verwandte Verbindungen, Verfahren zu ihrer Herstellung, Zwischenverbindungen und ihre Verwendung als Arzneimittel. |
Country Status (17)
Country | Link |
---|---|
US (1) | US4992448A (de) |
EP (1) | EP0428878B1 (de) |
JP (1) | JPH0725748B2 (de) |
KR (1) | KR0169109B1 (de) |
AT (1) | ATE123492T1 (de) |
AU (1) | AU626470B2 (de) |
CA (1) | CA2028287C (de) |
DE (1) | DE69019920T2 (de) |
DK (1) | DK0428878T3 (de) |
ES (1) | ES2074508T3 (de) |
FI (1) | FI905191A0 (de) |
IE (1) | IE903810A1 (de) |
IL (1) | IL96081A (de) |
NO (1) | NO904575L (de) |
PH (1) | PH27409A (de) |
PT (1) | PT95651B (de) |
ZA (1) | ZA908460B (de) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB9008818D0 (en) * | 1990-04-19 | 1990-06-13 | Ici Plc | Amine derivatives |
US5102891A (en) * | 1990-07-23 | 1992-04-07 | Hoechst-Roussel Pharmaceuticals Inc. | 1-(substituted pyridinylamino)-1H-indol-5-yl substituted carbamates |
ES2227769T3 (es) * | 1994-05-27 | 2005-04-01 | Glaxosmithkline S.P.A. | Derivados de quinolina como antagonistas del receptor nk3 de taquiquinina. |
US6455554B1 (en) | 1999-06-07 | 2002-09-24 | Targacept, Inc. | Oxopyridinyl pharmaceutical compositions and methods for use |
US6339093B1 (en) * | 1999-10-08 | 2002-01-15 | Hoffmann-La Roche Inc. | Isoquinoline derivatives |
CA2450073C (en) | 2001-07-25 | 2017-08-29 | Biomarin Pharmaceutical Inc. | Compositions and methods for modulating blood-brain barrier transport |
PT1889198E (pt) | 2005-04-28 | 2015-03-06 | Proteus Digital Health Inc | Sistema fármaco-informático |
US8795627B2 (en) | 2007-03-21 | 2014-08-05 | Raptor Pharmaceuticals Inc. | Treatment of liver disorders by administration of RAP conjugates |
WO2010095940A2 (en) | 2009-02-20 | 2010-08-26 | To-Bbb Holding B.V. | Glutathione-based drug delivery system |
NZ596876A (en) | 2009-05-06 | 2014-01-31 | Lab Skin Care Inc | Dermal delivery compositions comprising active agent-calcium phosphate particle complexes and methods of using the same |
US20120077778A1 (en) | 2010-09-29 | 2012-03-29 | Andrea Bourdelais | Ladder-Frame Polyether Conjugates |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3118884A (en) * | 1959-10-19 | 1964-01-21 | Schering Corp | Derivatives of 3-azaphenothiazine and 3-azaphenoxazine |
CH498114A (de) * | 1967-06-02 | 1970-10-31 | Ruetgerswerke Ag | Verfahren zur Herstellung von 2-N-substituierten 2-Amino-5-nitropyridinen |
US3495969A (en) * | 1967-09-25 | 1970-02-17 | Mobil Oil Corp | Substituted nitropyridines as herbicides |
US3576616A (en) * | 1969-05-15 | 1971-04-27 | Monsanto Co | Herbicidal compositions and methods |
US3721676A (en) * | 1969-11-12 | 1973-03-20 | Merck & Co Inc | Certain 3-amino-2(1h)pyridones |
US4042697A (en) * | 1972-10-19 | 1977-08-16 | Allen & Hanburys Limited | Isoquinolium compounds for treating diabetes |
US4190660A (en) * | 1978-08-11 | 1980-02-26 | Siu Patrick M | Anti-drug withdrawal syndrome composition and method of use |
GB2073736B (en) * | 1979-10-03 | 1984-02-01 | Ici Ltd | Process for preparing pyridinyloxyphenoxy compounds and derivatives thereof |
IE56702B1 (en) * | 1982-12-01 | 1991-11-06 | Usv Pharma Corp | Antiinflammatory antiallergic compounds |
GB8426584D0 (en) * | 1984-10-19 | 1984-11-28 | Beecham Group Plc | Compounds |
US4609733A (en) * | 1984-12-27 | 1986-09-02 | Ciba-Geigy Corporation | 3-keto-substituted-N-pyridylindoles |
DE3608089A1 (de) * | 1986-03-08 | 1987-09-10 | Schering Ag | Heteroaryl-oxy-ss-carbolinderivate, ihre herstellung und ihre verwendung als arzneimittel |
-
1989
- 1989-10-24 US US07/425,712 patent/US4992448A/en not_active Expired - Fee Related
-
1990
- 1990-10-22 KR KR1019900016853A patent/KR0169109B1/ko not_active IP Right Cessation
- 1990-10-22 EP EP90120238A patent/EP0428878B1/de not_active Expired - Lifetime
- 1990-10-22 DE DE69019920T patent/DE69019920T2/de not_active Expired - Fee Related
- 1990-10-22 PH PH41429A patent/PH27409A/en unknown
- 1990-10-22 ES ES90120238T patent/ES2074508T3/es not_active Expired - Lifetime
- 1990-10-22 AT AT90120238T patent/ATE123492T1/de not_active IP Right Cessation
- 1990-10-22 IL IL9608190A patent/IL96081A/en not_active IP Right Cessation
- 1990-10-22 DK DK90120238.2T patent/DK0428878T3/da active
- 1990-10-22 FI FI905191A patent/FI905191A0/fi not_active Application Discontinuation
- 1990-10-23 NO NO90904575A patent/NO904575L/no unknown
- 1990-10-23 ZA ZA908460A patent/ZA908460B/xx unknown
- 1990-10-23 PT PT95651A patent/PT95651B/pt not_active IP Right Cessation
- 1990-10-23 CA CA002028287A patent/CA2028287C/en not_active Expired - Fee Related
- 1990-10-23 AU AU64858/90A patent/AU626470B2/en not_active Ceased
- 1990-10-23 JP JP2283578A patent/JPH0725748B2/ja not_active Expired - Lifetime
- 1990-10-23 IE IE381090A patent/IE903810A1/en not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
IL96081A (en) | 1994-12-29 |
ZA908460B (en) | 1991-08-28 |
DE69019920D1 (de) | 1995-07-13 |
EP0428878B1 (de) | 1995-06-07 |
JPH03151378A (ja) | 1991-06-27 |
NO904575L (no) | 1991-04-25 |
IE903810A1 (en) | 1991-04-24 |
AU6485890A (en) | 1991-05-02 |
JPH0725748B2 (ja) | 1995-03-22 |
EP0428878A2 (de) | 1991-05-29 |
FI905191A0 (fi) | 1990-10-22 |
EP0428878A3 (en) | 1991-09-25 |
CA2028287A1 (en) | 1991-04-25 |
KR910007911A (ko) | 1991-05-30 |
PT95651A (pt) | 1991-09-13 |
PH27409A (en) | 1993-06-21 |
IL96081A0 (en) | 1991-07-18 |
ATE123492T1 (de) | 1995-06-15 |
ES2074508T3 (es) | 1995-09-16 |
US4992448A (en) | 1991-02-12 |
PT95651B (pt) | 1997-12-31 |
NO904575D0 (no) | 1990-10-23 |
CA2028287C (en) | 2001-04-03 |
KR0169109B1 (ko) | 1999-01-15 |
DK0428878T3 (da) | 1995-10-16 |
AU626470B2 (en) | 1992-07-30 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee |