ES2074508T3 - Benzocicloalquilaminopiridinaminas y compuestos afines, un procedimiento e intermediarios para su preparacion y su uso como medicamentos. - Google Patents

Benzocicloalquilaminopiridinaminas y compuestos afines, un procedimiento e intermediarios para su preparacion y su uso como medicamentos.

Info

Publication number
ES2074508T3
ES2074508T3 ES90120238T ES90120238T ES2074508T3 ES 2074508 T3 ES2074508 T3 ES 2074508T3 ES 90120238 T ES90120238 T ES 90120238T ES 90120238 T ES90120238 T ES 90120238T ES 2074508 T3 ES2074508 T3 ES 2074508T3
Authority
ES
Spain
Prior art keywords
preparation
benzocicloalquilaminopiridinaminas
intermediaries
medicines
procedure
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES90120238T
Other languages
English (en)
Inventor
Richard Charles Dr Effland
Joseph Thomas Dr Klein
Gordon Edward Olsen
Larry Davis
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Aventis Pharmaceuticals Inc
Original Assignee
Hoechst Roussel Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Roussel Pharmaceuticals Inc filed Critical Hoechst Roussel Pharmaceuticals Inc
Application granted granted Critical
Publication of ES2074508T3 publication Critical patent/ES2074508T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Display Devices Of Pinball Game Machines (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

Abstract

SE DESCRIBEN LOS COMPONENTES DE LA FORMULA. DONDE R ES HIDROGENO, ALQUILOBAJO, ARILOBAJOALQUILO O ALQUILOBAJOCARBONILO; K ES 0 O 1; M ES 1, 2 O 3; K+M ES 2 O 3; Y N ES 0 O 1; CUYOS COMPUESTOS SON UTILES COMO AGENTES ANTIINFLAMATORIOS TOPICOS PARA EL TRATAMIENTO DE VARIAS DUMATOSIS, INTERMEDIATOS DE ESTO Y PROCESOS PARA SU PREPARACION.
ES90120238T 1989-10-24 1990-10-22 Benzocicloalquilaminopiridinaminas y compuestos afines, un procedimiento e intermediarios para su preparacion y su uso como medicamentos. Expired - Lifetime ES2074508T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/425,712 US4992448A (en) 1989-10-24 1989-10-24 Benzocycloalkylaminopyridinamines and related compounds as topical antiinflammatory agents for the treatment of skin disorders

Publications (1)

Publication Number Publication Date
ES2074508T3 true ES2074508T3 (es) 1995-09-16

Family

ID=23687722

Family Applications (1)

Application Number Title Priority Date Filing Date
ES90120238T Expired - Lifetime ES2074508T3 (es) 1989-10-24 1990-10-22 Benzocicloalquilaminopiridinaminas y compuestos afines, un procedimiento e intermediarios para su preparacion y su uso como medicamentos.

Country Status (17)

Country Link
US (1) US4992448A (es)
EP (1) EP0428878B1 (es)
JP (1) JPH0725748B2 (es)
KR (1) KR0169109B1 (es)
AT (1) ATE123492T1 (es)
AU (1) AU626470B2 (es)
CA (1) CA2028287C (es)
DE (1) DE69019920T2 (es)
DK (1) DK0428878T3 (es)
ES (1) ES2074508T3 (es)
FI (1) FI905191A0 (es)
IE (1) IE903810A1 (es)
IL (1) IL96081A (es)
NO (1) NO904575L (es)
PH (1) PH27409A (es)
PT (1) PT95651B (es)
ZA (1) ZA908460B (es)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9008818D0 (en) * 1990-04-19 1990-06-13 Ici Plc Amine derivatives
US5102891A (en) * 1990-07-23 1992-04-07 Hoechst-Roussel Pharmaceuticals Inc. 1-(substituted pyridinylamino)-1H-indol-5-yl substituted carbamates
ES2227769T3 (es) * 1994-05-27 2005-04-01 Glaxosmithkline S.P.A. Derivados de quinolina como antagonistas del receptor nk3 de taquiquinina.
US6455554B1 (en) 1999-06-07 2002-09-24 Targacept, Inc. Oxopyridinyl pharmaceutical compositions and methods for use
US6339093B1 (en) * 1999-10-08 2002-01-15 Hoffmann-La Roche Inc. Isoquinoline derivatives
CA2450073C (en) 2001-07-25 2017-08-29 Biomarin Pharmaceutical Inc. Compositions and methods for modulating blood-brain barrier transport
PT1889198E (pt) 2005-04-28 2015-03-06 Proteus Digital Health Inc Sistema fármaco-informático
US8795627B2 (en) 2007-03-21 2014-08-05 Raptor Pharmaceuticals Inc. Treatment of liver disorders by administration of RAP conjugates
WO2010095940A2 (en) 2009-02-20 2010-08-26 To-Bbb Holding B.V. Glutathione-based drug delivery system
NZ596876A (en) 2009-05-06 2014-01-31 Lab Skin Care Inc Dermal delivery compositions comprising active agent-calcium phosphate particle complexes and methods of using the same
US20120077778A1 (en) 2010-09-29 2012-03-29 Andrea Bourdelais Ladder-Frame Polyether Conjugates

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3118884A (en) * 1959-10-19 1964-01-21 Schering Corp Derivatives of 3-azaphenothiazine and 3-azaphenoxazine
CH498114A (de) * 1967-06-02 1970-10-31 Ruetgerswerke Ag Verfahren zur Herstellung von 2-N-substituierten 2-Amino-5-nitropyridinen
US3495969A (en) * 1967-09-25 1970-02-17 Mobil Oil Corp Substituted nitropyridines as herbicides
US3576616A (en) * 1969-05-15 1971-04-27 Monsanto Co Herbicidal compositions and methods
US3721676A (en) * 1969-11-12 1973-03-20 Merck & Co Inc Certain 3-amino-2(1h)pyridones
US4042697A (en) * 1972-10-19 1977-08-16 Allen & Hanburys Limited Isoquinolium compounds for treating diabetes
US4190660A (en) * 1978-08-11 1980-02-26 Siu Patrick M Anti-drug withdrawal syndrome composition and method of use
GB2073736B (en) * 1979-10-03 1984-02-01 Ici Ltd Process for preparing pyridinyloxyphenoxy compounds and derivatives thereof
IE56702B1 (en) * 1982-12-01 1991-11-06 Usv Pharma Corp Antiinflammatory antiallergic compounds
GB8426584D0 (en) * 1984-10-19 1984-11-28 Beecham Group Plc Compounds
US4609733A (en) * 1984-12-27 1986-09-02 Ciba-Geigy Corporation 3-keto-substituted-N-pyridylindoles
DE3608089A1 (de) * 1986-03-08 1987-09-10 Schering Ag Heteroaryl-oxy-ss-carbolinderivate, ihre herstellung und ihre verwendung als arzneimittel

Also Published As

Publication number Publication date
IL96081A (en) 1994-12-29
ZA908460B (en) 1991-08-28
DE69019920D1 (de) 1995-07-13
EP0428878B1 (en) 1995-06-07
JPH03151378A (ja) 1991-06-27
NO904575L (no) 1991-04-25
IE903810A1 (en) 1991-04-24
AU6485890A (en) 1991-05-02
JPH0725748B2 (ja) 1995-03-22
EP0428878A2 (en) 1991-05-29
FI905191A0 (fi) 1990-10-22
EP0428878A3 (en) 1991-09-25
CA2028287A1 (en) 1991-04-25
KR910007911A (ko) 1991-05-30
PT95651A (pt) 1991-09-13
PH27409A (en) 1993-06-21
IL96081A0 (en) 1991-07-18
ATE123492T1 (de) 1995-06-15
US4992448A (en) 1991-02-12
PT95651B (pt) 1997-12-31
NO904575D0 (no) 1990-10-23
CA2028287C (en) 2001-04-03
KR0169109B1 (ko) 1999-01-15
DK0428878T3 (da) 1995-10-16
AU626470B2 (en) 1992-07-30
DE69019920T2 (de) 1995-11-16

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